Structures of thymidine kinase 1 of human and mycoplasmic origin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 52, 2004, Pages 17970-17975

  Welin, Martin ^a   Kosinska, Urszula ^a   Mikkelsen, Nils Egil ^a   Carnrot, Cecilia ^a   Zhu, Chunying ^b   Wang, Liya ^a   Eriksson, Staffan ^a   Munch Petersen, Birgitte ^b   Eklund, Hans ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b ROSKILDE UNIVERSITY   (Denmark)

Author keywords

Crystal structures; Deoxynucleotide metabolism; Prodrug activation

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; DEOXYRIBONUCLEOSIDE; DEOXYRIBONUCLEOSIDE KINASE; PHOSPHOTRANSFERASE; PRODRUG; RECA PROTEIN; THYMIDINE KINASE; THYMIDINE KINASE 1; THYMIDINE TRIPHOSPHATE; UNCLASSIFIED DRUG; ZIDOVUDINE; ZINC;

ARTICLE; CELL CYCLE; CRYSTAL STRUCTURE; DRUG ACTIVATION; ENZYME STRUCTURE; ENZYME SUBUNIT; HUMAN; HYDROGEN BOND; MOLECULAR EVOLUTION; MYCOPLASMA; NONHUMAN; NUCLEOTIDE METABOLISM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; UREAPLASMA UREALYTICUM;

AMINO ACID SEQUENCE; ANTIMETABOLITES; BINDING SITES; CRYSTALLIZATION; DEOXYRIBONUCLEOSIDES; EVOLUTION, MOLECULAR; HUMANS; HYDROGEN BONDING; IONS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOPLASMA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; THYMIDINE KINASE; THYMINE NUCLEOTIDES; UREAPLASMA UREALYTICUM; ZIDOVUDINE; ZINC;

MYCOPLASMA; UREAPLASMA UREALYTICUM;

EID: 11144222319     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0406332102     Document Type: Article

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