Biased coarse-grained molecular dynamics simulation approach for flexible fitting of X-ray structure into cryo electron microscopy maps

Journal of Structural Biology

Volumn 169, Issue 1, 2010, Pages 95-105

  Grubisic, Ivan ^a   Shokhirev, Maxim N ^a   Orzechowski, Marek ^a   Miyashita, Osamu ^a   Tama, Florence ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Cryo EM; Flexible fitting; Go model; Refinement; Targeted MD

Indexed keywords

ELONGATION FACTOR G; RNA POLYMERASE;

ACCURACY; ANALYTICAL ERROR; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; ESCHERICHIA COLI; INTERMETHOD COMPARISON; MATHEMATICAL MODEL; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROCESS MODEL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; REPRODUCIBILITY; STRUCTURE ANALYSIS; TEMPERATURE DEPENDENCE; VALIDITY; X RAY ANALYSIS;

CRYOELECTRON MICROSCOPY; CRYSTALLOGRAPHY, X-RAY; MOLECULAR DYNAMICS SIMULATION; PROTEINS;

ESCHERICHIA COLI;

EID: 72449186057     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2009.09.010     Document Type: Article

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