Model of the toxic complex of anthrax: Responsive conformational changes in both the lethal factor and the protective antigen heptamer

Protein Science

Volumn 15, Issue 9, 2006, Pages 2190-2200

  Tama, Florence ^a,c   Ren, Gang ^a,d   Brooks III, Charles L ^a   Mitra, Alok K ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c UNIVERSITY OF ARIZONA   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Anthrax toxin complex; Conformational change; Cryo EM; Lethal factor; Normal mode flexible fitting

Indexed keywords

ANTHRAX TOXIN; ANTIGEN; MONOMER; PROTECTIVE ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CRYOELECTRON MICROSCOPY; LETHAL GENE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ANTIGENS, BACTERIAL; BACTERIAL TOXINS; BINDING SITES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 33748211202     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.062293906     Document Type: Article

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