Spectroscopic and theoretical approaches for the determination of heparin saccharide structure and the study of protein-glycosaminoglycan complexes in solution

Current Medicinal Chemistry

Volumn 16, Issue 35, 2009, Pages 4750-4766

  Rudd, T R ^a   Yates, E A ^a   Hricovini M ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Circular dichroism; GAG; Heparin; Molecular modelling; NMR; Protein glycosaminoglycan complex; Structure

Indexed keywords

CARBOHYDRATE DERIVATIVE; GLYCOSAMINOGLYCAN PEPTIDE; HEPARAN SULFATE; HEPARIN; HEPARIN SACCHARIDE; POLYSACCHARIDE; UNCLASSIFIED DRUG;

CARBOHYDRATE ANALYSIS; CIRCULAR DICHROISM; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DENSITY FUNCTIONAL THEORY; DRUG MECHANISM; HUMAN; INFRARED SPECTROSCOPY; ISOTOPE LABELING; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOLECULAR PROBE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN DENATURATION; PROTEIN SECONDARY STRUCTURE; REVIEW; SPECTROSCOPY; STRUCTURE ANALYSIS; THEORETICAL STUDY;

ALGORITHMS; CIRCULAR DICHROISM; GLYCOSAMINOGLYCANS; HEPARIN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEINS; SOLUTIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 72449173485     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709789878193     Document Type: Review

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