CTLA-4-Ig activates Forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice

Journal of Experimental Medicine

Volumn 200, Issue 8, 2004, Pages 1051-1062

  Fallarino, Francesca ^a   Bianchi, Roberta ^a   Orabona, Ciriana ^a   Vacca, Carmine ^a   Belladonna, Maria L ^a   Fioretti, Maria C ^a   Serreze, David V ^b   Grohmann, Ursula ^a   Puccetti, Paolo ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b JACKSON LABORATORY   (United States)

Author keywords

CTLA 4; Dendritic cells; NOD mice; Signal transduction; Superoxide dismutase

Indexed keywords

1 METHYL DEXTRO TRYPTOPHAN; 2 METHOXYESTRADIOL; 2 MORPHOLINO 8 PHENYLCHROMONE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DISULFIDE; ENZYME INHIBITOR; GAMMA INTERFERON; GUANIDINOETHYL DISULFIDE; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN CHLORIDE; PEROXYNITRITE; PORPHYRIN DERIVATIVE; STAT1 PROTEIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; TRYPTOPHAN; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CELL PROTECTION; CONTROLLED STUDY; DENDRITIC CELL; DIABETES MELLITUS; FEMALE; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SOLUBILITY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CHROMONES; DENDRITIC CELLS; DNA-BINDING PROTEINS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; IMMUNOCONJUGATES; INTERFERON TYPE II; MALE; METALLOPORPHYRINS; MICE; MICE, INBRED NOD; MORPHOLINES; OXIDATIVE STRESS; PEROXYNITROUS ACID; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 7244231007     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20040942     Document Type: Article

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