-
1
-
-
0029978038
-
Checkpoints in the progression of autoimmune disease: Lessons from diabetes models
-
Andre, I., A. Gonzalez, B. Wang, J. Katz, C. Benoist, and D. Mathis. 1996. Checkpoints in the progression of autoimmune disease: lessons from diabetes models. Proc. Natl. Acad. Sci. USA 93:2260.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2260
-
-
Andre, I.1
Gonzalez, A.2
Wang, B.3
Katz, J.4
Benoist, C.5
Mathis, D.6
-
2
-
-
0028779842
-
The pathogenesis of insulin-dependent diabetes mellitus
-
Atkinson, M. A., and N. K. Maclaren. 1994. The pathogenesis of insulin-dependent diabetes mellitus. N. Engl. J. Med. 331:1428.
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 1428
-
-
Atkinson, M.A.1
Maclaren, N.K.2
-
3
-
-
0009680955
-
-
Academic Press, Orlando, FL
-
Tarui, S., Y. Tochino, and K. Nonaka. 1986. Insulitis and Type I Diabetes -Lessons from the NOD Mouse. Academic Press, Orlando, FL.
-
(1986)
Insulitis and Type I Diabetes -Lessons from the NOD Mouse
-
-
Tarui, S.1
Tochino, Y.2
Nonaka, K.3
-
4
-
-
0025104170
-
Essential contribution of macrophages to islet cell destruction in vivo and in vitro
-
Kolb, H., V. Burkart, B. Appels, H. Hanenberg, G. Kantwerl-Funke, U. Kiesel, J. Funda, U. Schraermeyer, and V. Kolb-Bachofen. 1990. Essential contribution of macrophages to islet cell destruction in vivo and in vitro. J. Autoimmun. 3:117.
-
(1990)
J. Autoimmun.
, vol.3
, pp. 117
-
-
Kolb, H.1
Burkart, V.2
Appels, B.3
Hanenberg, H.4
Kantwerl-Funke, G.5
Kiesel, U.6
Funda, J.7
Schraermeyer, U.8
Kolb-Bachofen, V.9
-
5
-
-
0025647147
-
Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptors on macrophages
-
Hutchings, P., H. Rosen, L. O'Reilly, E. Simpson, S. Gordon, and A. Cooke. 1990. Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptors on macrophages. Nature 348:639.
-
(1990)
Nature
, vol.348
, pp. 639
-
-
Hutchings, P.1
Rosen, H.2
O'Reilly, L.3
Simpson, E.4
Gordon, S.5
Cooke, A.6
-
8
-
-
0029826977
-
B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: Analysis of a new "speed congenic" stock of NOD.Ig μ null mice
-
Serreze, D. V., H. D. Chapman, D. S Varnum, M. S. Hanson, P. C. Reifsnyder, S. D. Richard, S. A. Fleming, E. H. Leiter, and L. D. Shultz. 1996. B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig μ null mice. J. Exp. Med. 184:2049.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 2049
-
-
Serreze, D.V.1
Chapman, H.D.2
Varnum, D.S.3
Hanson, M.S.4
Reifsnyder, P.C.5
Richard, S.D.6
Fleming, S.A.7
Leiter, E.H.8
Shultz, L.D.9
-
9
-
-
0030969531
-
B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice
-
Noorchashm, H., N. Noorchashm, J. Kern, S. Y. Rostami, C. F. Barker, and A. Naji. 1997. B-cells are required for the initiation of insulitis and sialitis in nonobese diabetic mice. Diabetes 46:941.
-
(1997)
Diabetes
, vol.46
, pp. 941
-
-
Noorchashm, H.1
Noorchashm, N.2
Kern, J.3
Rostami, S.Y.4
Barker, C.F.5
Naji, A.6
-
10
-
-
8544271680
-
Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice
-
Akashi, T., S. Nagafuchi, K. Anzai, S. Kondo, D. Kitamura, S. Wakana, J. Ono, M. Kikuchi, Y. Niho, and T. Watanabe. 1997. Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice. Int. Immunol. 9:1159.
-
(1997)
Int. Immunol.
, vol.9
, pp. 1159
-
-
Akashi, T.1
Nagafuchi, S.2
Anzai, K.3
Kondo, S.4
Kitamura, D.5
Wakana, S.6
Ono, J.7
Kikuchi, M.8
Niho, Y.9
Watanabe, T.10
-
12
-
-
13344294394
-
CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells
-
Wong, F. S., I. Visintin, L. Wen, R. A. Flavell, and C. A. Janeway, Jr. 1996. CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. J. Exp. Med. 183:67.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 67
-
-
Wong, F.S.1
Visintin, I.2
Wen, L.3
Flavell, R.A.4
Janeway C.A., Jr.5
-
13
-
-
0032214715
-
Local expression of TNFα in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens
-
Green, E. A., E. E. Eynon, and R. A. Flavell. 1998. Local expression of TNFα in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens. Immunity 9:733.
-
(1998)
Immunity
, vol.9
, pp. 733
-
-
Green, E.A.1
Eynon, E.E.2
Flavell, R.A.3
-
14
-
-
0027170482
-
Antigen-presenting cells in adoptively transferred and spontaneous autoimmune diabetes
-
Lo, D., C. R. Reilly, B. Scott, R. Liblau, H. O. McDevitt, and L. C. Burkly. 1993. Antigen-presenting cells in adoptively transferred and spontaneous autoimmune diabetes. Eur. J. Immunol. 23:1693.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 1693
-
-
Lo, D.1
Reilly, C.R.2
Scott, B.3
Liblau, R.4
McDevitt, H.O.5
Burkly, L.C.6
-
15
-
-
0029927928
-
A new foreign policy: MHC class I molecules monitor the outside world
-
Rock, K. L. 1996. A new foreign policy: MHC class I molecules monitor the outside world. Immunol. Today 17:131.
-
(1996)
Immunol. Today
, vol.17
, pp. 131
-
-
Rock, K.L.1
-
17
-
-
0030845586
-
+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses
-
+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J. Exp. Med. 186:47.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 47
-
-
Shuford, W.W.1
Klussman, K.2
Tritchler, D.D.3
Loo, D.T.4
Chalupny, J.5
Siadak, A.W.6
Brown, T.J.7
Emswiler, J.8
Raecho, H.9
Larsen, C.P.10
Pearson, T.C.11
Ledbetter, J.A.12
Aruffo, A.13
Mittler, R.S.14
-
18
-
-
0029030393
-
Fibroblasts as efficient antigen-presenting cells in lymphoid organs
-
Kundig, T. M., M. F. Bachmann, C. DiPaolo, J. J. Simard, M. Battegay, H. Lother, A. Gessner, K. Kuhlcke, P. S. Ohashi, H. Hengartner, et al. 1995. Fibroblasts as efficient antigen-presenting cells in lymphoid organs. Science 268: 1343.
-
(1995)
Science
, vol.268
, pp. 1343
-
-
Kundig, T.M.1
Bachmann, M.F.2
Dipaolo, C.3
Simard, J.J.4
Battegay, M.5
Lother, H.6
Gessner, A.7
Kuhlcke, K.8
Ohashi, P.S.9
Hengartner, H.10
-
19
-
-
0030975532
-
Antigen localisation regulates immune responses in a dose- and time-dependent fashion: A geographical view of immune reactivity
-
Zinkernagel, R. M., S. Ehl, P. Aichele, S. Oehen, T. Kundig, and H. Hengartner. 1997. Antigen localisation regulates immune responses in a dose- and time-dependent fashion: a geographical view of immune reactivity. Immunol. Rev. 156: 199.
-
(1997)
Immunol. Rev.
, vol.156
, pp. 199
-
-
Zinkernagel, R.M.1
Ehl, S.2
Aichele, P.3
Oehen, S.4
Kundig, T.5
Hengartner, H.6
-
20
-
-
0025108875
-
Loss of pancreatic islet tolerance induced by β-cell expression of interferon-γ
-
Sarvetnick, N., J. Shizuru, D. Liggitt, L. Martin, B. McIntyre, A. Gregory, T. Parslow, and T. Stewart. 1990. Loss of pancreatic islet tolerance induced by β-cell expression of interferon-γ. Nature 346:844.
-
(1990)
Nature
, vol.346
, pp. 844
-
-
Sarvetnick, N.1
Shizuru, J.2
Liggitt, D.3
Martin, L.4
McIntyre, B.5
Gregory, A.6
Parslow, T.7
Stewart, T.8
-
21
-
-
0028842108
-
Sensitization to self (virus) antigen by in situ expression of murine interferon-γ
-
Lee, M. S., M. von Herrath, H. Reiser, M. B. Oldstone, and N. Sarvetnick. 1995. Sensitization to self (virus) antigen by in situ expression of murine interferon-γ. J. Clin. Invest. 95:486.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 486
-
-
Lee, M.S.1
Von Herrath, M.2
Reiser, H.3
Oldstone, M.B.4
Sarvetnick, N.5
-
22
-
-
0030030057
-
Cytokines and nitric oxide in islet inflammation and diabetes
-
McDaniel, M. L., G. Kwon, J. R. Hill, C. A. Marshall, and J. A. Corbett. 1996. Cytokines and nitric oxide in islet inflammation and diabetes. Proc. Soc. Exp. Biol. Med. 211:24.
-
(1996)
Proc. Soc. Exp. Biol. Med.
, vol.211
, pp. 24
-
-
McDaniel, M.L.1
Kwon, G.2
Hill, J.R.3
Marshall, C.A.4
Corbett, J.A.5
-
23
-
-
0030731917
-
Nitric oxide primes pancreatic β cells for Fas-mediated destruction in insulin-dependent diabetes mellitus
-
Stassi, G., R. D. Maria, G. Trucco, W. Rudert, R. Testi, A. Galluzzo, C. Giordano, and M. Trucco. 1997. Nitric oxide primes pancreatic β cells for Fas-mediated destruction in insulin-dependent diabetes mellitus. J. Exp. Med. 186:1193.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1193
-
-
Stassi, G.1
Maria, R.D.2
Trucco, G.3
Rudert, W.4
Testi, R.5
Galluzzo, A.6
Giordano, C.7
Trucco, M.8
-
24
-
-
0023872192
-
Establichment of mouse cell lines which constitutively produce large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors
-
Karasuyama, H., and F. Melchers. 1988. Establichment of mouse cell lines which constitutively produce large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol. 18:97.
-
(1988)
Eur. J. Immunol.
, vol.18
, pp. 97
-
-
Karasuyama, H.1
Melchers, F.2
-
25
-
-
0020317336
-
Resistance of established islet allografts to rejection by antibody and complement
-
Agostino, M., S. J. Prowse, and K. J. Lafferty. 1982. Resistance of established islet allografts to rejection by antibody and complement. Aust. J. Exp. Biol. Med. Sci. 60:219.
-
(1982)
Aust. J. Exp. Biol. Med. Sci.
, vol.60
, pp. 219
-
-
Agostino, M.1
Prowse, S.J.2
Lafferty, K.J.3
-
26
-
-
0025878776
-
NIT-1, a pancreatic β-cell line established from a transgenic NOD/Lt mouse
-
Hamaguchi, K., H. R. Gaskins, and E. H. Leiter. 1991. NIT-1, a pancreatic β-cell line established from a transgenic NOD/Lt mouse. Diabetes 40:842.
-
(1991)
Diabetes
, vol.40
, pp. 842
-
-
Hamaguchi, K.1
Gaskins, H.R.2
Leiter, E.H.3
-
27
-
-
0030005411
-
The harmony of the spheres: Inducible nitric oxide synthase and related genes in pancreatic β cells
-
Eizirik, D. L., M. Flodstrom, A. E. Karlsen, and N. Welsh. 1996. The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic β cells. Diabetologia 39:875.
-
(1996)
Diabetologia
, vol.39
, pp. 875
-
-
Eizirik, D.L.1
Flodstrom, M.2
Karlsen, A.E.3
Welsh, N.4
-
28
-
-
0030997703
-
Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin-1
-
Heitmeier, M. R., A. L. Scarim, and J. A. Corbett. 1997. Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin-1 J. Biol. Chem. 272:13697.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13697
-
-
Heitmeier, M.R.1
Scarim, A.L.2
Corbett, J.A.3
-
29
-
-
0032521025
-
Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes
-
Arnush, M., A. L. Scarim, M. R. Heitmeier, C. B. Kelly, and J. A. Corbett. 1998. Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes. J. Immunol. 160:2684.
-
(1998)
J. Immunol.
, vol.160
, pp. 2684
-
-
Arnush, M.1
Scarim, A.L.2
Heitmeier, M.R.3
Kelly, C.B.4
Corbett, J.A.5
-
31
-
-
0033579877
-
The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice
-
Jun, H. S., C. S. Yoon, L. Zbytnuik, N. van Rooijen, and J. W. Yoon. 1999. The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice. J. Exp. Med. 189:347.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 347
-
-
Jun, H.S.1
Yoon, C.S.2
Zbytnuik, L.3
Van Rooijen, N.4
Yoon, J.W.5
-
32
-
-
0032538522
-
Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking
-
Randolph, G. J., S. Beaulieu, S. Lebecque, R. M. Steinman, and W. A. Muller. 1998. Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking. Science 282:480.
-
(1998)
Science
, vol.282
, pp. 480
-
-
Randolph, G.J.1
Beaulieu, S.2
Lebecque, S.3
Steinman, R.M.4
Muller, W.A.5
-
34
-
-
0023784346
-
IFN-γ and tumor necrosis factor-α: Cytotoxicity to murine islets of Langerhans
-
Campbell, I. L., A. Iscaro, and L. C. Harrison. 1988. IFN-γ and tumor necrosis factor-α: cytotoxicity to murine islets of Langerhans. J. Immunol. 141:2325.
-
(1988)
J. Immunol.
, vol.141
, pp. 2325
-
-
Campbell, I.L.1
Iscaro, A.2
Harrison, L.C.3
-
35
-
-
0029948898
-
Genetic absence of γ-interferon delays but does not prevent diabetes in NOD mice
-
Hultgren, B., X. Huang, N. Dybdal, and T. A. Stewart. 1996. Genetic absence of γ-interferon delays but does not prevent diabetes in NOD mice. Diabetes 45:812.
-
(1996)
Diabetes
, vol.45
, pp. 812
-
-
Hultgren, B.1
Huang, X.2
Dybdal, N.3
Stewart, T.A.4
-
36
-
-
0031456802
-
Interferon-γ impacts at multiple points during the progression of autoimmune diabetes
-
Wang, B., I. Andre, A. Gonzalez, J. D. Katz, M. Aguet, C. Benoist, and D. Mathis. 1997. Interferon-γ impacts at multiple points during the progression of autoimmune diabetes. Proc. Nat. Acad. Sci. USA 94:13844.
-
(1997)
Proc. Nat. Acad. Sci. USA
, vol.94
, pp. 13844
-
-
Wang, B.1
Andre, I.2
Gonzalez, A.3
Katz, J.D.4
Aguet, M.5
Benoist, C.6
Mathis, D.7
-
37
-
-
0033526068
-
In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor α
-
Pakala, S. V., M. Chivetta, C. B. Kelly, and J. D. Katz. 1999. In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor α. J. Exp. Med. 189:1053.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1053
-
-
Pakala, S.V.1
Chivetta, M.2
Kelly, C.B.3
Katz, J.D.4
-
38
-
-
0028949955
-
Cytokines as mediators of autoimmune diabetes and diabetic complications
-
Pankewycz, O. G., J. X. Guan, and J. F. Benedict. 1995. Cytokines as mediators of autoimmune diabetes and diabetic complications. Endocr. Rev. 16:164.
-
(1995)
Endocr. Rev.
, vol.16
, pp. 164
-
-
Pankewycz, O.G.1
Guan, J.X.2
Benedict, J.F.3
-
39
-
-
0031871335
-
An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus
-
Rabinovitch A. 1998. An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus. Diab. Metabol. Rev. 14:129.
-
(1998)
Diab. Metabol. Rev.
, vol.14
, pp. 129
-
-
Rabinovitch, A.1
-
40
-
-
0030777296
-
Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2
-
Rothe, H., N. A. Jenkins, N. G. Copeland, and H. Kolb. 1997. Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2. J. Clin. Invest. 99:469.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 469
-
-
Rothe, H.1
Jenkins, N.A.2
Copeland, N.G.3
Kolb, H.4
-
41
-
-
0028989087
-
IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice
-
Rabinovitch, A., W. L. Suarez Pinzon, O. Sorensen, R. C. Bleackley, and R, F. Power. 1995. IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlates with autoimmune diabetes in nonobese diabetic mice. J. Immunol. 154:4874.
-
(1995)
J. Immunol.
, vol.154
, pp. 4874
-
-
Rabinovitch, A.1
Suarez Pinzon, W.L.2
Sorensen, O.3
Bleackley, R.C.4
Power, R.F.5
-
42
-
-
0033104985
-
+ T cells are required for IFN-γ gene expression in pancreatic islets and autoimmune diabetes development in biobreeding rats
-
+ T cells are required for IFN-γ gene expression in pancreatic islets and autoimmune diabetes development in biobreeding rats. J. Autoimmun. 12:109.
-
(1999)
J. Autoimmun.
, vol.12
, pp. 109
-
-
El-Sheikh, A.1
Suarez-Pinzon, W.L.2
Power, R.F.3
Rabinovitch, A.4
|