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Volumn 3, Issue 8, 2008, Pages

Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 1; DORSOMORPHIN; NOGGIN; PROTEIN INHIBITOR; (6 (4 (2 PIPERIDIN 1 YLETHOXY)PHENYL)) 3 PYRIDIN 4 YLPYRAZOLO(1,5 A)PYRIMIDINE; (6-(4-(2-PIPERIDIN-1-YLETHOXY)PHENYL))-3-PYRIDIN-4-YLPYRAZOLO(1,5-A)PYRIMIDINE; BONE MORPHOGENETIC PROTEIN; HEMOGLOBIN; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 51449091152     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002904     Document Type: Article
Times cited : (184)

References (30)
  • 1
    • 33646789159 scopus 로고    scopus 로고
    • Stem cells as a source of regenerative cardiomyocytes
    • Fukuda K, Yuasa S (2006) Stem cells as a source of regenerative cardiomyocytes. Circ Res 98: 1002-1013.
    • (2006) Circ Res , vol.98 , pp. 1002-1013
    • Fukuda, K.1    Yuasa, S.2
  • 2
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme MA, Chen KY, Naumova AV, Muskheli V, Fugate JA, et al. (2007) Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol 25: 1015-1024.
    • (2007) Nat Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3    Muskheli, V.4    Fugate, J.A.5
  • 3
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 4
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5
  • 5
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • Okita K, Ichisaka T, Yamanaka S (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-317.
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 6
    • 34249908901 scopus 로고    scopus 로고
    • In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
    • Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, et al. (2007) In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448: 318-324.
    • (2007) Nature , vol.448 , pp. 318-324
    • Wernig, M.1    Meissner, A.2    Foreman, R.3    Brambrink, T.4    Ku, M.5
  • 8
    • 24944570013 scopus 로고    scopus 로고
    • Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation
    • Kouskoff V, Lacaud G, Schwantz S, Fehling HJ, Keller G (2005) Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation. Proc Natl Acad Sci U S A 102: 13170-13175.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13170-13175
    • Kouskoff, V.1    Lacaud, G.2    Schwantz, S.3    Fehling, H.J.4    Keller, G.5
  • 9
    • 1242336840 scopus 로고    scopus 로고
    • Small molecules that induce cardiomyogenesis in embryonic stem cells
    • Wu X, Ding S, Ding Q, Gray NS, Schultz PG (2004) Small molecules that induce cardiomyogenesis in embryonic stem cells. J Am Chem Soc 126: 1590-1591.
    • (2004) J Am Chem Soc , vol.126 , pp. 1590-1591
    • Wu, X.1    Ding, S.2    Ding, Q.3    Gray, N.S.4    Schultz, P.G.5
  • 10
    • 22844439586 scopus 로고    scopus 로고
    • Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells
    • Yuasa S, Itabashi Y, Koshimizu U, Tanaka T, Sugimura K, et al. (2005) Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells. Nat Biotechnol 23: 607-611.
    • (2005) Nat Biotechnol , vol.23 , pp. 607-611
    • Yuasa, S.1    Itabashi, Y.2    Koshimizu, U.3    Tanaka, T.4    Sugimura, K.5
  • 11
    • 34250802982 scopus 로고    scopus 로고
    • Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells
    • Ueno S, Weidinger G, Osugi T, Kohn AD, Golob JL, et al. (2007) Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells. Proc Natl Acad Sci U S A 104: 9685-9690.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 9685-9690
    • Ueno, S.1    Weidinger, G.2    Osugi, T.3    Kohn, A.D.4    Golob, J.L.5
  • 12
    • 33845928762 scopus 로고    scopus 로고
    • Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis
    • Naito AT, Shiojima I, Akazawa H, Hidaka K, Morisaki T, et al. (2006) Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci U S A 103: 19812-19817.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 19812-19817
    • Naito, A.T.1    Shiojima, I.2    Akazawa, H.3    Hidaka, K.4    Morisaki, T.5
  • 13
    • 34250756145 scopus 로고    scopus 로고
    • A chemical approach to stem cell biology
    • Emre N, Coleman R, Ding S (2007) A chemical approach to stem cell biology. Curr Opin Chem Biol 11: 252-258.
    • (2007) Curr Opin Chem Biol , vol.11 , pp. 252-258
    • Emre, N.1    Coleman, R.2    Ding, S.3
  • 14
    • 33750456216 scopus 로고    scopus 로고
    • Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages
    • Kattman SJ, Huber TL, Keller GM (2006) Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev Cell 11: 723-732.
    • (2006) Dev Cell , vol.11 , pp. 723-732
    • Kattman, S.J.1    Huber, T.L.2    Keller, G.M.3
  • 16
    • 26444585020 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in stem cells and cancer
    • Mishra L, Derynck R, Mishra B (2005) Transforming growth factor-beta signaling in stem cells and cancer. Science 310: 68-71.
    • (2005) Science , vol.310 , pp. 68-71
    • Mishra, L.1    Derynck, R.2    Mishra, B.3
  • 17
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • Zhou G, Myers R, Li Y, Chen Y, Shen X, et al. (2001) Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108: 1167-1174.
    • (2001) J Clin Invest , vol.108 , pp. 1167-1174
    • Zhou, G.1    Myers, R.2    Li, Y.3    Chen, Y.4    Shen, X.5
  • 18
    • 37249010753 scopus 로고    scopus 로고
    • Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
    • Yu PB, Hong CC, Sachidanandan C, Babitt JL, Deng DY, et al. (2008) Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol 4: 33-41.
    • (2008) Nat Chem Biol , vol.4 , pp. 33-41
    • Yu, P.B.1    Hong, C.C.2    Sachidanandan, C.3    Babitt, J.L.4    Deng, D.Y.5
  • 19
    • 0030023987 scopus 로고    scopus 로고
    • Transgenic remodeling of the contractile apparatus in the mammalian heart
    • Palermo J, Gulick J, Colbert M, Fewell J, Robbins J (1996) Transgenic remodeling of the contractile apparatus in the mammalian heart. Circ Res 78: 504-509.
    • (1996) Circ Res , vol.78 , pp. 504-509
    • Palermo, J.1    Gulick, J.2    Colbert, M.3    Fewell, J.4    Robbins, J.5
  • 21
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • Ying QL, Nichols J, Chambers I, Smith A (2003) BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115: 281-292.
    • (2003) Cell , vol.115 , pp. 281-292
    • Ying, Q.L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 22
    • 0032841613 scopus 로고    scopus 로고
    • MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube
    • Saga Y, Miyagawa-Tomita S, Takagi A, Kitajima S, Miyazaki J, et al. (1999) MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube. Development 126: 3437-3447.
    • (1999) Development , vol.126 , pp. 3437-3447
    • Saga, Y.1    Miyagawa-Tomita, S.2    Takagi, A.3    Kitajima, S.4    Miyazaki, J.5
  • 23
    • 34247243159 scopus 로고    scopus 로고
    • Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells
    • Liu Y, Asakura M, Inoue H, Nakamura T, Sano M, et al. (2007) Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells. Proc Natl Acad Sci U S A 104: 3859-3864.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3859-3864
    • Liu, Y.1    Asakura, M.2    Inoue, H.3    Nakamura, T.4    Sano, M.5
  • 24
    • 36048953007 scopus 로고    scopus 로고
    • Characterization of embryoid bodies of mouse embryonic stem cells formed under various culture conditions and estimation of differentiation status of such bodies
    • Koike M, Sakaki S, Amano Y, Kurosawa H (2007) Characterization of embryoid bodies of mouse embryonic stem cells formed under various culture conditions and estimation of differentiation status of such bodies. J Biosci Bioeng 104: 294-299.
    • (2007) J Biosci Bioeng , vol.104 , pp. 294-299
    • Koike, M.1    Sakaki, S.2    Amano, Y.3    Kurosawa, H.4
  • 25
    • 0029583152 scopus 로고
    • Induction of avian cardiac myogenesis by anterior endoderm
    • Schultheiss TM, Xydas S, Lassar AB (1995) Induction of avian cardiac myogenesis by anterior endoderm. Development 121: 4203-4214.
    • (1995) Development , vol.121 , pp. 4203-4214
    • Schultheiss, T.M.1    Xydas, S.2    Lassar, A.B.3
  • 26
    • 0031018002 scopus 로고    scopus 로고
    • A role for bone morphogenetic proteins in the induction of cardiac myogenesis
    • Schultheiss TM, Burch JB, Lassar AB (1997) A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev 11: 451-462.
    • (1997) Genes Dev , vol.11 , pp. 451-462
    • Schultheiss, T.M.1    Burch, J.B.2    Lassar, A.B.3
  • 27
    • 34547482623 scopus 로고    scopus 로고
    • Vessel and blood specification override cardiac potential in anterior mesoderm
    • Schoenebeck JJ, Keegan BR, Yelon D (2007) Vessel and blood specification override cardiac potential in anterior mesoderm. Dev Cell 13: 254-267.
    • (2007) Dev Cell , vol.13 , pp. 254-267
    • Schoenebeck, J.J.1    Keegan, B.R.2    Yelon, D.3
  • 28
    • 33845457194 scopus 로고    scopus 로고
    • Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification
    • Moretti A, Caron L, Nakano A, Lam JT, Bernshausen A, et al. (2006) Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 127: 1151-1165.
    • (2006) Cell , vol.127 , pp. 1151-1165
    • Moretti, A.1    Caron, L.2    Nakano, A.3    Lam, J.T.4    Bernshausen, A.5
  • 29
    • 0035937728 scopus 로고    scopus 로고
    • Development. The path to the heart and the road not taken
    • Olson EN (2001) Development. The path to the heart and the road not taken. Science 291: 2327-2328.
    • (2001) Science , vol.291 , pp. 2327-2328
    • Olson, E.N.1
  • 30
    • 0035252357 scopus 로고    scopus 로고
    • Inhibition of Wnt activity induces heart formation from posterior mesoderm
    • Marvin MJ, Di Rocco G, Gardiner A, Bush SM, Lassar AB (2001) Inhibition of Wnt activity induces heart formation from posterior mesoderm. Genes Dev 15: 316-327.
    • (2001) Genes Dev , vol.15 , pp. 316-327
    • Marvin, M.J.1    Di Rocco, G.2    Gardiner, A.3    Bush, S.M.4    Lassar, A.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.