Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors

PLoS ONE

Volumn 4, Issue 11, 2009, Pages

  Volke, Melanie ^a   Gale, Daniel P ^b   Maegdefrau, Ulrike ^c   Schley, Gunnar ^a   Klanke, Bernd ^a   Bosserhoff, Anja Katrin ^c   Maxwell, Patrick H ^b   Eckardt, Kai Uwe ^a   Warnecke, Christina ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD71 ANTIGEN; HEPCIDIN; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IRON REGULATORY FACTOR; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSFERRIN RECEPTOR 2; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANTIMICROBIAL CATIONIC PEPTIDE; CHROMONE DERIVATIVE; HYPOXIA INDUCIBLE FACTOR 1; INTERLEUKIN 6; LEUKOCYTE ANTIGEN; MORPHOLINE DERIVATIVE; TFR2 PROTEIN, HUMAN; TRANSFERRIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DOWN REGULATION; GENE DELETION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; CHEMISTRY; METABOLISM; MOLECULAR GENETICS;

MUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID MOTIFS; ANIMALS; ANTIGENS, CD; ANTIMICROBIAL CATIONIC PEPTIDES; BASE SEQUENCE; CHROMONES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INTERLEUKIN-6; IRON-REGULATORY PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MORPHOLINES; PROMOTER REGIONS, GENETIC; RECEPTORS, TRANSFERRIN;

EID: 70849095971     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007875     Document Type: Article

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