HIF-2α, but not HIF-1α, promotes iron absorption in mice

Journal of Clinical Investigation

Volumn 119, Issue 5, 2009, Pages 1159-1166

  Mastrogiannaki, Maria ^a,b   Matak, Pavle ^a,b   Keith, Brian ^c   Simon, M Celeste ^c   Vaulont, Sophie ^a,b   Peyssonnaux, Carole ^a,b  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPCIDIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IRON; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; ANTIMICROBIAL CATIONIC PEPTIDE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CATION TRANSPORT PROTEIN; CYTOCHROME B; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HEMOGLOBIN; HIF1A PROTEIN, MOUSE; METAL TRANSPORTING PROTEIN 1; SOLUTE CARRIER FAMILY 11 (PROTON COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2; SOLUTE CARRIER FAMILY 11- (PROTON-COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2;

5' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DUODENUM; GENE DELETION; GENE FUNCTION; HUMAN; HUMAN CELL; HYPOXIA; INTESTINE ABSORPTION; INTESTINE CELL; IRON ABSORPTION; IRON BALANCE; IRON BLOOD LEVEL; IRON DEFICIENCY; KNOCKOUT MOUSE; LIVER LEVEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSACTIVATION; TRANSCRIPTION REGULATION; ANIMAL; BLOOD; C57BL MOUSE; CELL HYPOXIA; CELL STRAIN CACO 2; CHEMISTRY; CYTOLOGY; DNA RESPONSIVE ELEMENT; ERYTHROCYTE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; LIVER; METABOLISM; PHYSIOLOGY; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CACO-2 CELLS; CATION TRANSPORT PROTEINS; CELL HYPOXIA; CYTOCHROMES B; DUODENUM; ERYTHROCYTES; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEMOGLOBINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTESTINAL ABSORPTION; IRON; LIVER; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RESPONSE ELEMENTS; TRANSCRIPTIONAL ACTIVATION;

EID: 66449124596     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI38499     Document Type: Article

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