Iron-Mediated Degradation of IRP2, an Unexpected Pathway Involving a 2-Oxoglutarate-Dependent Oxygenase Activity

Molecular and Cellular Biology

Volumn 24, Issue 3, 2004, Pages 954-965

  Wang, Jian ^a   Chen, Guohua ^a   Muckenthaler, Martina ^c   Galy, Bruno ^c   Hentze, Matthias W ^c   Pantopoulos, Kostas ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ACETYLCYSTEINE; ALPHA TOCOPHEROL; ASCORBIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRON; IRON REGULATORY PROTEIN 2; OXYGENASE;

ANIMAL CELL; ARTICLE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IRON BALANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN STABILITY; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; CYSTEINE; GENES, REPORTER; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IRON; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; KETOGLUTARIC ACIDS; MICE; MUTATION; OXIDATION-REDUCTION; OXYGENASES; PROTEIN STRUCTURE, TERTIARY; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 1642458415     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.3.954-965.2004     Document Type: Article

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