-
1
-
-
0001359591
-
Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
-
Napoli C, Lemieux C, Jorgensen R. Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 1990;2(4):279-289
-
(1990)
Plant Cell
, vol.2
, Issue.4
, pp. 279-289
-
-
Napoli, C.1
Lemieux, C.2
Jorgensen, R.3
-
2
-
-
0026441194
-
Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
-
Romano N, Macino G. Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Mol Microbiol 1992;6(22):3343-3353
-
(1992)
Mol Microbiol
, vol.6
, Issue.22
, pp. 3343-3353
-
-
Romano, N.1
MacIno, G.2
-
3
-
-
0029024475
-
Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
-
Guo S, Kemphues KJ. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 1995;81(4):611-620
-
(1995)
Cell
, vol.81
, Issue.4
, pp. 611-620
-
-
Guo, S.1
Kemphues, K.J.2
-
4
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
-
DOI 10.1038/35888
-
Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans. Nature 1998;391(6669):806-811 (Pubitemid 28099681)
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
5
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in drosophila cells
-
Hammond SM, Bernstein E, Beach D, Hannon GJ. An RNA-directed nuclease mediates post-transcriptional gene silencing in drosophila cells. Nature 2000;404(6775):293-296
-
(2000)
Nature
, vol.404
, Issue.6775
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
6
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001;411(6836):494-498
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
-
7
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 2004;116(2):281-297
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 281-297
-
-
Bartel, D.P.1
-
8
-
-
63049085576
-
MicroRNAs-the micro steering wheel of tumour metastases
-
Nicoloso MS, Spizzo R, Shimizu M, et al. MicroRNAs-the micro steering wheel of tumour metastases. Nat Rev Cancer 2009;9(4):293-302
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.4
, pp. 293-302
-
-
Nicoloso, M.S.1
Spizzo, R.2
Shimizu, M.3
-
9
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006;6(11):857-866
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.11
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
10
-
-
33751163757
-
MicroRNA expression and function in cancer
-
Garzon R, Fabbri M, Cimmino A, et al. MicroRNA expression and function in cancer. Trends Mol Med 2006;12(12):580-587
-
(2006)
Trends Mol Med
, vol.12
, Issue.12
, pp. 580-587
-
-
Garzon, R.1
Fabbri, M.2
Cimmino, A.3
-
11
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
DOI 10.1101/gad.862301
-
Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001;15(2):188-200 (Pubitemid 32107664)
-
(2001)
Genes and Development
, vol.15
, Issue.2
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
12
-
-
0033615491
-
A species of small antisense RNA in posttranscriptional gene silencing in plants
-
Hamilton AJ, Baulcombe DC. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 1999;286(5441):950-952
-
(1999)
Science
, vol.286
, Issue.5441
, pp. 950-952
-
-
Hamilton, A.J.1
Baulcombe, D.C.2
-
13
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001;409(6818):363-366
-
(2001)
Nature
, vol.409
, Issue.6818
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
14
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez J, Patkaniowska A, Urlaub H, et al. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 2002;110(5):563-574
-
(2002)
Cell
, vol.110
, Issue.5
, pp. 563-574
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
-
15
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu J, Carmell MA, Rivas FV, et al. Argonaute2 is the catalytic engine of mammalian RNAi. Science 2004;305(5689):1437-1441
-
(2004)
Science
, vol.305
, Issue.5689
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
-
16
-
-
27744537851
-
Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
-
Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 2005;123(4):631-640
-
(2005)
Cell
, vol.123
, Issue.4
, pp. 631-640
-
-
Gregory, R.I.1
Chendrimada, T.P.2
Cooch, N.3
Shiekhattar, R.4
-
17
-
-
0038385504
-
RNA interference in mammalian cells by chemically-modified RNA
-
Braasch DA, Jensen S, Liu Y, et al. RNA interference in mammalian cells by chemically-modified RNA. Biochemistry 2003;42(26):7967-7975
-
(2003)
Biochemistry
, vol.42
, Issue.26
, pp. 7967-7975
-
-
Braasch, D.A.1
Jensen, S.2
Liu, Y.3
-
18
-
-
0041331496
-
SiRNA function in RNAi: A chemical modification analysis
-
Chiu YL, Rana TM. siRNA function in RNAi: A chemical modification analysis. RNA 2003;9(9):1034-1048
-
(2003)
RNA
, vol.9
, Issue.9
, pp. 1034-1048
-
-
Chiu, Y.L.1
Rana, T.M.2
-
19
-
-
0037391391
-
A simple and cost-effective method for producing small interfering RNAs with high efficacy
-
Published online 7 February 2003, doi: 10.1093/nar/gng038
-
Sohail M, Doran G, Riedemann J, et al. A simple and cost-effective method for producing small interfering RNAs with high efficacy. Nucleic Acids Res 2003;31(7):e38. Published online 7 February 2003, doi: 10.1093/nar/gng038
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.7
-
-
Sohail, M.1
Doran, G.2
Riedemann, J.3
-
20
-
-
0012756249
-
RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase
-
Donze O, Picard D. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res 2002;30(10):e46
-
(2002)
Nucleic Acids Res
, vol.30
, Issue.10
-
-
Donze, O.1
Picard, D.2
-
21
-
-
1542306855
-
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase
-
Kim DH, Longo M, Han Y, et al. Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase. Nat Biotechnol 2004;22(3):321-325
-
(2004)
Nat Biotechnol
, vol.22
, Issue.3
, pp. 321-325
-
-
Kim, D.H.1
Longo, M.2
Han, Y.3
-
22
-
-
59849090457
-
Cellular delivery in vivo of siRNA-based therapeutics
-
Aigner A. Cellular delivery in vivo of siRNA-based therapeutics. Curr Pharm Des 2008;14(34):3603-3619
-
(2008)
Curr Pharm des
, vol.14
, Issue.34
, pp. 3603-3619
-
-
Aigner, A.1
-
23
-
-
34249064319
-
RNA interference and innate immunity
-
Sioud M. RNA interference and innate immunity. Adv Drug Deliv Rev 2007;59(2-3):153-163
-
(2007)
Adv Drug Deliv Rev
, vol.59
, Issue.2-3
, pp. 153-163
-
-
Sioud, M.1
-
24
-
-
34547866454
-
Nonviral in vivo delivery of therapeutic small interfering RNAs
-
Aigner A. Nonviral in vivo delivery of therapeutic small interfering RNAs. Curr Opin Mol Ther 2007;9(4):345-352
-
(2007)
Curr Opin Mol Ther
, vol.9
, Issue.4
, pp. 345-352
-
-
Aigner, A.1
-
25
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296(5567):550-553
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
26
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison PJ, Caudy AA, Bernstein E, et al. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev 2002;16(8):948-958
-
(2002)
Genes Dev
, vol.16
, Issue.8
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
-
27
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
Harborth J, Elbashir SM, Vandenburgh K, et al. Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Antisense Nucleic Acid Drug Dev 2003;13(2):83-105
-
(2003)
Antisense Nucleic Acid Drug Dev
, vol.13
, Issue.2
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
-
28
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee NS, Dohjima T, Bauer G, et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 2002;20(5):500-505
-
(2002)
Nat Biotechnol
, vol.20
, Issue.5
, pp. 500-505
-
-
Lee, N.S.1
Dohjima, T.2
Bauer, G.3
-
29
-
-
84926974293
-
Viral delivery of shRNA
-
Appasani K, editor, . Cambridge, UK: Cambridge University Press
-
Mao Y, Mello C, Lamarcq L, et al. Viral delivery of shRNA. In: Appasani K, editor, RNA interference technology. Cambridge, UK: Cambridge University Press; 2004. p. 161-173
-
(2004)
RNA Interference Technology
, pp. 161-173
-
-
Mao, Y.1
Mello, C.2
Lamarcq, L.3
-
30
-
-
33749681890
-
Delivery of RNA interference
-
Li CX, Parker A, Menocal E, et al. Delivery of RNA interference. Cell Cycle 2006;5(18):2103-2109
-
(2006)
Cell Cycle
, vol.5
, Issue.18
, pp. 2103-2109
-
-
Li, C.X.1
Parker, A.2
Menocal, E.3
-
31
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm D, Streetz KL, Jopling CL, et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 2006;441(7092):537-541
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
-
32
-
-
51349090473
-
Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1
-
Hacein-Bey-Abina S, Garrigue A, Wang GP, et al. Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1. J Clin Invest 2008;118(9):3132-3142
-
(2008)
J Clin Invest
, vol.118
, Issue.9
, pp. 3132-3142
-
-
Hacein-Bey-Abina, S.1
Garrigue, A.2
Wang, G.P.3
-
33
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S, von Kalle C, Schmidt M, et al. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N Engl J Med 2003;348(3):255-256
-
(2003)
N Engl J Med
, vol.348
, Issue.3
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
34
-
-
12544259115
-
A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication
-
Xiang R, Mizutani N, Luo Y, et al. A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication. Cancer Res 2005;65(2):553-561
-
(2005)
Cancer Res
, vol.65
, Issue.2
, pp. 553-561
-
-
Xiang, R.1
Mizutani, N.2
Luo, Y.3
-
35
-
-
0035839429
-
A phase i trial of genetically modified Salmonella typhimurium expressing cytosine deaminase (TAPET-CD VNP20029) administered by intratumoral injection in combination with 5-fluorocytosine for patients with advanced or metastatic cancer
-
Protocol no: CL-017. Version: April 9 2001
-
Cunningham C, Nemunaitis J. A phase I trial of genetically modified Salmonella typhimurium expressing cytosine deaminase (TAPET-CD, VNP20029) administered by intratumoral injection in combination with 5-fluorocytosine for patients with advanced or metastatic cancer. Protocol no: CL-017. Version: April 9, 2001. Hum Gene Ther 2001;12(12):1594-1596
-
(2001)
Hum Gene Ther
, vol.12
, Issue.12
, pp. 1594-1596
-
-
Cunningham, C.1
Nemunaitis, J.2
-
36
-
-
0036019203
-
Tumor-targeted Salmonella expressing cytosine deaminase as an anticancer agent
-
King I, Bermudes D, Lin S, et al. Tumor-targeted Salmonella expressing cytosine deaminase as an anticancer agent. Hum Gene Ther 2002;13(10):1225-1233
-
(2002)
Hum Gene Ther
, vol.13
, Issue.10
, pp. 1225-1233
-
-
King, I.1
Bermudes, D.2
Lin, S.3
-
38
-
-
33645243935
-
Use of bacteria in anti-cancer therapies
-
Ryan RM, Green J, Lewis CE. Use of bacteria in anti-cancer therapies. Bioessays 2006;28(1):84-94
-
(2006)
Bioessays
, vol.28
, Issue.1
, pp. 84-94
-
-
Ryan, R.M.1
Green, J.2
Lewis, C.E.3
-
39
-
-
33846576538
-
Facultative or obligate anaerobic bacteria have the potential for multimodality therapy of solid tumours
-
Wei MQ, Ellem KA, Dunn P, et al. Facultative or obligate anaerobic bacteria have the potential for multimodality therapy of solid tumours. Eur J Cancer 2007;43(3):490-496
-
(2007)
Eur J Cancer
, vol.43
, Issue.3
, pp. 490-496
-
-
Wei, M.Q.1
Ellem, K.A.2
Dunn, P.3
-
40
-
-
33745085925
-
Short hairpin RNA-expressing bacteria elicit RNA interference in mammals
-
Xiang S, Fruehauf J, Li CJ. Short hairpin RNA-expressing bacteria elicit RNA interference in mammals. Nat Biotechnol 2006;24(6):697-702
-
(2006)
Nat Biotechnol
, vol.24
, Issue.6
, pp. 697-702
-
-
Xiang, S.1
Fruehauf, J.2
Li, C.J.3
-
41
-
-
0023667057
-
Identification of invasin: A protein that allows enteric bacteria to penetrate cultured mammalian cells
-
Isberg RR, Voorhis DL, Falkow S. Identification of invasin: A protein that allows enteric bacteria to penetrate cultured mammalian cells. Cell 1987;50(5):769-778
-
(1987)
Cell
, vol.50
, Issue.5
, pp. 769-778
-
-
Isberg, R.R.1
Voorhis, D.L.2
Falkow, S.3
-
42
-
-
0026580262
-
The invasin protein of Yersinia enterocolitica: Internalization of invasin-bearing bacteria by eukaryotic cells is associated with reorganization of the cytoskeleton
-
Young VB, Falkow S, Schoolnik GK. The invasin protein of Yersinia enterocolitica: Internalization of invasin-bearing bacteria by eukaryotic cells is associated with reorganization of the cytoskeleton. J Cell Biol 1992;116(1):197-207
-
(1992)
J Cell Biol
, vol.116
, Issue.1
, pp. 197-207
-
-
Young, V.B.1
Falkow, S.2
Schoolnik, G.K.3
-
44
-
-
0031721556
-
Functional gene transfer from intracellular bacteria to mammalian cells
-
Grillot-Courvalin C, Goussard S, Huetz F, et al. Functional gene transfer from intracellular bacteria to mammalian cells. Nat Biotechnol 1998;16(9):862-866
-
(1998)
Nat Biotechnol
, vol.16
, Issue.9
, pp. 862-866
-
-
Grillot-Courvalin, C.1
Goussard, S.2
Huetz, F.3
-
45
-
-
0038601430
-
Cytosolic delivery of antisense oligonucleotides by listeriolysin O-containing liposomes
-
Mathew E, Hardee GE, Bennett CF, Lee KD. Cytosolic delivery of antisense oligonucleotides by listeriolysin O-containing liposomes. Gene Ther 2003;10(13):1105-1115
-
(2003)
Gene Ther
, vol.10
, Issue.13
, pp. 1105-1115
-
-
Mathew, E.1
Hardee, G.E.2
Bennett, C.F.3
Lee, K.D.4
-
46
-
-
13244284605
-
Beta-Catenin activates the growth factor endothelin-1 in colon cancer cells
-
Kim TH, Xiong H, Zhang Z, Ren B. Beta-Catenin activates the growth factor endothelin-1 in colon cancer cells. Oncogene 2005;24(4):597-604
-
(2005)
Oncogene
, vol.24
, Issue.4
, pp. 597-604
-
-
Kim, T.H.1
Xiong, H.2
Zhang, Z.3
Ren, B.4
-
47
-
-
70450217576
-
Bacterial vectors for RNAi delivery
-
Slator R, Hill C, editors, Austin, TX, USA: Landes Bioscience and Springer Science
-
Nguyen T, Fruehauf J. Bacterial vectors for RNAi delivery. In: Slator R, Hill C, editors, Patho-Biotechnology. Austin, TX, USA: Landes Bioscience and Springer Science; 2008. p. 121-125
-
(2008)
Patho-Biotechnology
, pp. 121-125
-
-
Nguyen, T.1
Fruehauf, J.2
-
48
-
-
0034849063
-
Eukaryotic expression plasmid transfer from the intracellular bacterium Listeria monocytogenes to host cells
-
Hense M, Domann E, Krusch S, et al. Eukaryotic expression plasmid transfer from the intracellular bacterium Listeria monocytogenes to host cells. Cell Microbiol 2001;3(9):599-609
-
(2001)
Cell Microbiol
, vol.3
, Issue.9
, pp. 599-609
-
-
Hense, M.1
Domann, E.2
Krusch, S.3
-
49
-
-
0035477892
-
Transfer of eukaryotic expression plasmids to mammalian host cells by bacterial carriers
-
DOI 10.1016/S0958-1669(00)00247-0
-
Weiss S, Chakraborty T. Transfer of eukaryotic expression plasmids to mammalian host cells by bacterial carriers. Curr Opin Biotechnol 2001;12(5):467-472 (Pubitemid 32972171)
-
(2001)
Current Opinion in Biotechnology
, vol.12
, Issue.5
, pp. 467-472
-
-
Weiss, S.1
Chakraborty, T.2
-
50
-
-
0036489891
-
Live bacteria as anticancer agents and tumor-selective protein delivery vectors
-
Bermudes D, Zheng LM, King IC. Live bacteria as anticancer agents and tumor-selective protein delivery vectors. Curr Opin Drug Discov Devel 2002;5(2):194-199
-
(2002)
Curr Opin Drug Discov Devel
, vol.5
, Issue.2
, pp. 194-199
-
-
Bermudes, D.1
Zheng, L.M.2
King, I.C.3
-
51
-
-
0033758836
-
In vivo correction of genetic defects of monocyte/macrophages using attenuated Salmonella as oral vectors for targeted gene delivery
-
Paglia P, Terrazzini N, Schulze K, et al. In vivo correction of genetic defects of monocyte/macrophages using attenuated Salmonella as oral vectors for targeted gene delivery. Gene Ther 2000;7(20):1725-1730
-
(2000)
Gene Ther
, vol.7
, Issue.20
, pp. 1725-1730
-
-
Paglia, P.1
Terrazzini, N.2
Schulze, K.3
-
52
-
-
0019407618
-
Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
-
Hoiseth SK, Stocker BA. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature 1981;291(5812):238-239
-
(1981)
Nature
, vol.291
, Issue.5812
, pp. 238-239
-
-
Hoiseth, S.K.1
Stocker, B.A.2
-
53
-
-
0030854392
-
Tumor-targeted salmonella as a novel anticancer vector
-
Pawelek JM, Low KB, Bermudes D. Tumor-targeted salmonella as a novel anticancer vector. Cancer Res 1997;57(20):4537-4544
-
(1997)
Cancer Res
, vol.57
, Issue.20
, pp. 4537-4544
-
-
Pawelek, J.M.1
Low, K.B.2
Bermudes, D.3
-
54
-
-
0032927753
-
Lipid A mutant salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivo
-
Low KB, Ittensohn M, Le T, et al. Lipid A mutant salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivo. Nat Biotechnol 1999;17(1):37-41
-
(1999)
Nat Biotechnol
, vol.17
, Issue.1
, pp. 37-41
-
-
Low, K.B.1
Ittensohn Le M, T.2
-
55
-
-
34250857547
-
Intratumoral delivery and suppression of prostate tumor growth by attenuated salmonella enterica serovar typhimurium carrying plasmid-based small interfering RNAs
-
Zhang L, Gao L, Zhao L, et al. Intratumoral delivery and suppression of prostate tumor growth by attenuated salmonella enterica serovar typhimurium carrying plasmid-based small interfering RNAs. Cancer Res 2007;67(12):5859-5864
-
(2007)
Cancer Res
, vol.67
, Issue.12
, pp. 5859-5864
-
-
Zhang, L.1
Gao, L.2
Zhao, L.3
-
56
-
-
0003582512
-
A two-component regulatory system (phoP phoQ) controls salmonella typhimurium virulence
-
Miller SI, Kukral AM, Mekalanos JJ. A two-component regulatory system (phoP phoQ) controls salmonella typhimurium virulence. Proc Natl Acad Sci USA 1989;86(13):5054-5058
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, Issue.13
, pp. 5054-5058
-
-
Miller, S.I.1
Kukral, A.M.2
Mekalanos, J.J.3
-
57
-
-
0343575172
-
Salmonella typhimurium phoP virulence gene is a transcriptional regulator
-
Groisman EA, Chiao E, Lipps CJ, Heffron F. Salmonella typhimurium phoP virulence gene is a transcriptional regulator. Proc Natl Acad Sci USA 1989;86(18):7077-7081
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, Issue.18
, pp. 7077-7081
-
-
Groisman, E.A.1
Chiao, E.2
Lipps, C.J.3
Heffron, F.4
-
58
-
-
0024445956
-
Virulence and vaccine potential of phoP mutants of Salmonella typhimurium
-
Galan JE, Curtiss R 3rd. Virulence and vaccine potential of phoP mutants of Salmonella typhimurium. Microb Pathog 1989;6(6):433-443
-
(1989)
Microb Pathog
, vol.6
, Issue.6
, pp. 433-443
-
-
Galan, J.E.1
Curtiss Iii, R.2
-
59
-
-
0011736531
-
Mutants of salmonella typhimurium that cannot survive within the macrophage are avirulent
-
Fields PI, Swanson RV, Haidaris CG, Heffron F. Mutants of salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc Natl Acad Sci USA 1986;83(14):5189-5193
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, Issue.14
, pp. 5189-5193
-
-
Fields, P.I.1
Swanson, R.V.2
Haidaris, C.G.3
Heffron, F.4
-
60
-
-
0034116071
-
Pilot study of phoP/phoQ-deleted salmonella enterica serovar typhimurium expressing helicobacter pylori urease in adult volunteers
-
Angelakopoulos H, Hohmann EL. Pilot study of phoP/phoQ-deleted salmonella enterica serovar typhimurium expressing helicobacter pylori urease in adult volunteers. Infect Immun 2000;68(4):2135-2141
-
(2000)
Infect Immun
, vol.68
, Issue.4
, pp. 2135-2141
-
-
Angelakopoulos, H.1
Hohmann, E.L.2
-
61
-
-
0035816147
-
Salmonella-based tumor-targeted cancer therapy: Tumor amplified protein expression therapy (TAPET) for diagnostic imaging
-
Tjuvajev J, Blasberg R, Luo X, et al. Salmonella-based tumor-targeted cancer therapy: Tumor amplified protein expression therapy (TAPET) for diagnostic imaging. J Control Release 2001;74(1-3):313-315
-
(2001)
J Control Release
, vol.74
, Issue.1-3
, pp. 313-315
-
-
Tjuvajev, J.1
Blasberg, R.2
Luo, X.3
-
62
-
-
0032726122
-
STAT proteins as novel targets for cancer therapy
-
Catlett-Falcone R, Dalton WS, Jove R. STAT proteins as novel targets for cancer therapy. Curr Opin Oncol 1999;11(6):490-496
-
(1999)
Curr Opin Oncol
, vol.11
, Issue.6
, pp. 490-496
-
-
Catlett-Falcone, R.1
Dalton, W.S.2
Jove, R.3
-
63
-
-
0037112367
-
Constitutive activation of Stat3 in human prostate tumors and cell lines: Direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells
-
Mora LB, Buettner R, Seigne J, et al. Constitutive activation of Stat3 in human prostate tumors and cell lines: Direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells. Cancer Res 2002;62(22):6659-6666
-
(2002)
Cancer Res
, vol.62
, Issue.22
, pp. 6659-6666
-
-
Mora, L.B.1
Buettner, R.2
Seigne, J.3
-
64
-
-
0033034365
-
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
-
Takeda K, Clausen BE, Kaisho T, et al. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 1999;10(1):39-49
-
(1999)
Immunity
, vol.10
, Issue.1
, pp. 39-49
-
-
Takeda, K.1
Clausen, B.E.2
Kaisho, T.3
-
65
-
-
39549102220
-
STAT3: A critical transcription activator in angiogenesis
-
Chen Z, Han ZC. STAT3: A critical transcription activator in angiogenesis. Med Res Rev 2008;28(2):185-200
-
(2008)
Med Res Rev
, vol.28
, Issue.2
, pp. 185-200
-
-
Chen, Z.1
Han, Z.C.2
-
66
-
-
38849199799
-
STAT3 as a target for inducing apoptosis in solid and hematological tumors
-
Al Zaid Siddiquee K, Turkson J. STAT3 as a target for inducing apoptosis in solid and hematological tumors. Cell Res 2008;18(2):254-267
-
(2008)
Cell Res
, vol.18
, Issue.2
, pp. 254-267
-
-
Al Zaid Siddiquee, K.1
Turkson, J.2
-
67
-
-
44349087591
-
STAT 3 as a target for cancer drug discovery
-
Costantino L, Barlocco D. STAT 3 as a target for cancer drug discovery. Curr Med Chem 2008;15(9):834-843
-
(2008)
Curr Med Chem
, vol.15
, Issue.9
, pp. 834-843
-
-
Costantino, L.1
Barlocco, D.2
-
68
-
-
20444486755
-
GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells
-
Barnich N, Hisamatsu T, Aguirre JE, et al. GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells. J Biol Chem 2005;280(19):19021-19026
-
(2005)
J Biol Chem
, vol.280
, Issue.19
, pp. 19021-19026
-
-
Barnich, N.1
Hisamatsu, T.2
Aguirre, J.E.3
-
69
-
-
0037451235
-
GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction
-
Lufei C, Ma J, Huang G, et al. GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction. EMBO J 2003;22(6):1325-1335
-
(2003)
EMBO J
, vol.22
, Issue.6
, pp. 1325-1335
-
-
Lufei, C.1
Ma, J.2
Huang, G.3
-
70
-
-
0042925385
-
The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3
-
Zhang J, Yang J, Roy SK, et al. The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3. Proc Natl Acad Sci USA 2003;100(16):9342-9347
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.16
, pp. 9342-9347
-
-
Zhang, J.1
Yang, J.2
Roy, S.K.3
-
71
-
-
30944440768
-
High-throughput screening of effective siRNAs from RNAi libraries delivered via bacterial invasion
-
Zhao HF, L'Abbe D, Jolicoeur N, et al. High-throughput screening of effective siRNAs from RNAi libraries delivered via bacterial invasion. Nat Methods 2005;2(12):967-973
-
(2005)
Nat Methods
, vol.2
, Issue.12
, pp. 967-973
-
-
Zhao, H.F.1
L'Abbe, D.2
Jolicoeur, N.3
-
72
-
-
65949106130
-
Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation
-
Aouadi M, Tesz GJ, Nicoloro SM, et al. Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation. Nature 2009;458(7242):1180- 1184
-
(2009)
Nature
, vol.458
, Issue.7242
, pp. 1180-1184
-
-
Aouadi, M.1
Tesz, G.J.2
Nicoloro, S.M.3
-
73
-
-
13844280638
-
Synthetic shRNAs as potent RNAi triggers
-
Siolas D, Lerner C, Burchard J, et al. Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol 2005;23(2):227-231
-
(2005)
Nat Biotechnol
, vol.23
, Issue.2
, pp. 227-231
-
-
Siolas, D.1
Lerner, C.2
Burchard, J.3
-
74
-
-
13844281898
-
Synthetic dsRNA dicer substrates enhance RNAi potency and efficacy
-
Kim DH, Behlke MA, Rose SD, et al. Synthetic dsRNA dicer substrates enhance RNAi potency and efficacy. Nat Biotechnol 2005;23(2):222-226
-
(2005)
Nat Biotechnol
, vol.23
, Issue.2
, pp. 222-226
-
-
Kim, D.H.1
Behlke, M.A.2
Rose, S.D.3
-
75
-
-
35148845281
-
Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway
-
John M, Constien R, Akinc A, et al. Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway. Nature 2007;449(7163):745-747
-
(2007)
Nature
, vol.449
, Issue.7163
, pp. 745-747
-
-
John, M.1
Constien, R.2
Akinc, A.3
-
76
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota J, Chivukula RR, O'Donnell KA, et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 2009;137(6):1005-1017
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'Donnell, K.A.3
-
77
-
-
14144251067
-
Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium
-
DOI 10.1073/pnas.0408422102
-
Zhao M, Yang M, Li XM, et al. Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing salmonella typhimurium. Proc Natl Acad Sci USA 2005;102(3):755-760 (Pubitemid 40282738)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.3
, pp. 755-760
-
-
Zhao, M.1
Yang, M.2
Li, X.-M.3
Jiang, P.4
Baranov, E.5
Li, S.6
Xu, M.7
Penman, S.8
Hoffman, R.M.9
-
78
-
-
33747878325
-
Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude mice
-
Zhao M, Yang M, Ma H, et al. Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude mice. Cancer Res 2006;66(15):7647-7652
-
(2006)
Cancer Res
, vol.66
, Issue.15
, pp. 7647-7652
-
-
Zhao, M.1
Yang, M.2
Ma, H.3
-
79
-
-
0034572185
-
Tumor amplified protein expression therapy: Salmonella as a tumor-selective protein delivery vector
-
Zheng LM, Luo X, Feng M, et al. Tumor amplified protein expression therapy: Salmonella as a tumor-selective protein delivery vector. Oncol Res 2001;12(3):127-135
-
(2001)
Oncol Res
, vol.12
, Issue.3
, pp. 127-135
-
-
Zheng, L.M.1
Luo, X.2
Feng, M.3
-
80
-
-
14744302999
-
Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: Development of a single-dose oral tetanus vaccine
-
Chatfield SN, Charles IG, Makoff AJ, et al. Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: Development of a single-dose oral tetanus vaccine. Biotechnology (NY) 1992;10(8):888-892
-
(1992)
Biotechnology (NY)
, vol.10
, Issue.8
, pp. 888-892
-
-
Chatfield, S.N.1
Charles, I.G.2
Makoff, A.J.3
-
81
-
-
0032873474
-
Safety and immunogenicity of phoP/phoQ-deleted Salmonella typhi expressing helicobacter pylori urease in adult volunteers
-
DiPetrillo MD, Tibbetts T, Kleanthous H, et al. Safety and immunogenicity of phoP/phoQ-deleted Salmonella typhi expressing helicobacter pylori urease in adult volunteers. Vaccine 1999;18(5-6):449-459
-
(1999)
Vaccine
, vol.18
, Issue.5-6
, pp. 449-459
-
-
Dipetrillo, M.D.1
Tibbetts, T.2
Kleanthous, H.3
-
82
-
-
0029799771
-
PhoP/phoQ-deleted Salmonella typhi (Ty800) is a safe and immunogenic single-dose typhoid fever vaccine in volunteers
-
Hohmann EL, Oletta CA, Killeen KP, Miller SI. phoP/phoQ-deleted Salmonella typhi (Ty800) is a safe and immunogenic single-dose typhoid fever vaccine in volunteers. J Infect Dis 1996;173(6):1408-1414
-
(1996)
J Infect Dis
, vol.173
, Issue.6
, pp. 1408-1414
-
-
Hohmann, E.L.1
Oletta, C.A.2
Killeen, K.P.3
Miller, S.I.4
-
83
-
-
0032750184
-
Live attenuated salmonella: A paradigm of mucosal vaccines
-
Sirard JC, Niedergang F, Kraehenbuhl JP. Live attenuated salmonella: A paradigm of mucosal vaccines. Immunol Rev 1999;171:5-26
-
(1999)
Immunol Rev
, vol.171
, pp. 5-26
-
-
Sirard, J.C.1
Niedergang, F.2
Kraehenbuhl, J.P.3
-
84
-
-
0036140068
-
Phase i study of the intravenous administration of attenuated salmonella typhimurium to patients with metastatic melanoma
-
Toso JF, Gill VJ, Hwu P, et al. Phase I study of the intravenous administration of attenuated salmonella typhimurium to patients with metastatic melanoma. J Clin Oncol 2002;20(1):142-152
-
(2002)
J Clin Oncol
, vol.20
, Issue.1
, pp. 142-152
-
-
Toso, J.F.1
Gill, V.J.2
Hwu, P.3
|