Viral delivery of shRNA

RNA Interference Technology: From Basic Science to Drug Development

Volumn 9780521836777, Issue , 2005, Pages 161-173

  Mao, Ying ^a   Mello, Chris ^a   Lamarcq, Laurence ^a   Scherer, Brad ^a   Quinn, Thomas ^a   Wong, Patty ^a   Farmer, Andrew ^a  

^a BD BIOSCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84926974293     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1017/CBO9780511546402.014     Document Type: Chapter

References (47)

1. Abremski, K. and Hoess, R. (1984). Bacteriophage P1 site-specific recombination. Purification and properties of the Cre recombinase protein. Journal of Biological Chemistry, 259, 1509-1514.
2. Agami, R. and Bernards, R. (2000). Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage. Cell, 102, 55-66.
3. Armentano, D., Yu S-F., Kantoff, P. W., von Ruden, T., Anderson, W. F., and Gilboa, E. (1987). Effect of internal viral sequences on the utility of retroviral vectors. Journal of Virology, 61, 1647-1650.
4. Baltimore, D. (2001). Our genome unveiled. Nature, 409, 814-816.
5. Barton, G. M., and Medzhitov, R. (2002). Retroviral delivery of small interfering RNA into primary cells. Proceedings of the National Academy of Sciences USA, 99, 14943-14945.
6. Brummelkamp, T. R., Bernards, R., and Agami, R. (2002a). A system for stable expression of short interfering RNAs in mammalian cells. Science, 296, 550-553.
7. Brummelkamp, T. R., Bernards, R., and Agami, R. (2002b). Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell, 2, 243-247.
8. Capecchi, M. R. (1989). Altering the genome by homologous recombination. Science, 244, 1288-1292.
9. Correll, P. H., Colilla, S., and Karlsson, S. (1994). Retroviral vector design for long-term expression in murine hematopoietic cells in vivo. Blood, 84, 1812-1822.
10. Devroe, E., and Silver, P. A. (2002). Retrovirus-delivered siRNA. BMC Biotechnology, 2, 15.
11. Donze, O., and Picard, D. (2002). RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Research, 30, e46.
12. Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001). Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 411, 494-498.
13. Emerman, M., and Temin, H. M. (1984). Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism. Cell, 39, 449-467.
14. Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., and Mello C. C. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 391, 806-811.
15. Graham, F. L., and Prevec L. (1991). Manipulation of adenovirus vectors. Methods in Molecular Biology, 7, 109-128.
16. Hacein-Bey-Abina, S., von Kalle, C., Schmidt, M., Le Deist, F., Wulffraat, N., McIntyre, E., Radford, I., Villeval, J. L., Fraser, C. C., Cavazzana-Calvo, M., and Fischer A. (2003). A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. New England Journal of Medicine, 348, 255-256.
17. Hammond, S. M., Caudy, A. A., and Hannon, G. J. (2001). Post-transcriptional gene silencing by double-stranded RNA. Nature Reviews Genetics, 2, 110-119.
18. Harlow, E. (1992). Retinoblastoma. For our eyes only. Nature, 359, 270-271.
19. Hawley, T. S., Sabourin, L. A., and Hawley, R. G. (1989). Comparative analysis of retroviral vector expression in mouse embryonal carcinoma cells. Plasmid, 22, 120-131.
20. Hemann, M. T., Fridman, J. S., Zilfou, J. T., Hernando, E., Paddison, P. J., Cordon-Cardo, C., Hannon, G. J., and Lowe, S. W. (2003). An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nature Genetics, 33, 396-400.
21. Hütvagner, G., and Zamore, P. D. (2002). RNAi: Nature abhors a double-strand. Current Opinion in Genetics and Development, 12, 225-232.
22. Ilves, H., Barske, C., Junker, U., Bohnlein, E., and Veres, G. (1996). Retroviral vectors designed for targeted expression of RNA polymerase III-driven transcripts: A comparative study. Gene, 171, 203-208.
23. Julius, M. A., Yan, Q., Zheng, Z., and Kitajewski, J. (2000). Q Vectors, Bicistronic retroviral vectors for gene transfer. BioTechniques, 28, 702-707.
24. Kawasaki, H., and Taira, K. (2003). Short hairpin type of dsRNAs that are controlled by tRNA (Val). promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells. Nucleic Acids Research, 31, 700-707.
25. Lee, E. Y., Chang, C. Y., Hu, N., Wang, Y. C., Lai, C. C., Herrup, K., Lee, W. H., and Bradley, A. (1992). Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature, 359, 288-294.
26. Lee, N. S., Dohjima, T., Bauer, G., Li, H., Li, M-J., Ehsani, A., Salvaterra, P., and Rossi, J. (2002). Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nature Biotechnology, 20, 500-505.
27. Liu, C. Y., Flesken-Nikitin, A., Li, S., Zeng, Y., and Lee, W. H. (1996). Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development. Genes & Development, 10, 1835-1843.
28. Miller, V. M., Xia, H., Marrs, G. L., Gouvion, C. M., Lee, G., Davidson, B. L., and Paulson, H. L. (2003). Allele-specific silencing of dominant disease genes. Proceedings of the National Academy of Sciences USA, 100, 195-7200.
29. Miyagishi, M., and Taira, K. (2002). U6-promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nature Biotechnology, 20, 497-500.
30. Mizuguchi, H., and Kay, M. A. (1998). Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method. Human Gene Therapy, 9, 2577-2583.
31. Nykanen, A., Haley, B., and Zamore, P. D. (2001). ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell, 107, 309-321.
32. Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J., and Conklin, D. S. (2002). Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes & Development, 16, 948-958.
33. Paul, C. P., Good, P. D., Winer, I., and Engelke, D. R. (2002). Effective expression of small interfering RNA in human cells. Nature Biotechnology, 20, 505-508.
34. Qin, X. F., An, D. S., Chen, I. S., and Baltimore, D. (2003). Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proceedings of the National Academy of Sciences USA, 100, 183-188.
35. Reynolds, A., Leake, D., Boese, Q., Scaringe, S., Marshall, W. S. and Khvorova, A. (2004). Rational siRNA design for RNA interference. Nature Biotechnology, 22, 326-330.
36. Robertson, E., Bradley, A., Kuehn, M., and Evans, M. (1986). Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector. Nature, 323, 445-448.
37. Rubinson, D. A., Dillon, C. P., Kwiatkowski, A. V., Sievers, C., Yang, L., Kopinja, J., Zhang, M., McManus, M. T., Gertler, F. B., Scott, M. L., and Van Parijs. L. (2003). A lentivirusbased system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nature Genetics, 33, 401-406.
38. Schroder, A. R., Shinn, P., Chen, H., Berry, C., Ecker, J. R., and Bushman, F. (2002). HIV-1 integration in the human genome favors active genes and local hotspots. Cell, 110, 521-529.
39. Sedivy, J. M., and Dutriaux, A. (1999). Gene targeting and somatic cell genetics-a rebirth or a coming of age? Trends in Genetics, 15, 88-90.
40. Sharp, P. A. (2001). RNA Interference-2001. Genes & Development, 15, 485-490.
41. Shen, C., Buck, A. K., Liu, X., Winkler, M., and Reske, S. N. (2003). Gene silencing by adenovirus-delivered siRNA. Federation of European Biochemical Society Letters, 539, 111-114.
42. Tiscornia, G., Singer, O., Ikawa, M., and Verma, I. M. (2003). A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proceedings of the National Academy of Sciences USA, 100, 1844-1848.
43. Yu, J-Y., DeRuiter, S. L., and Turner, D. L. (2002). RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proceedings of the National Academy of Sciences USA, 99, 6047-6052.
44. Yu, S. F., von Ruden, T., Kantoff, P. W., Garber, C., Seiberg, M., Ruther, U., Anderson, W. F., Wagner, E. F., and Gilboa, E. (1986). Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells. Proceedings of the National Academy of Sciences USA, 83, 3194-3198.
45. Van der Weyden, L., Adams, D. J., and Bradley, A. (2002). Tools for targeted manipulation of the mouse genome. Physiological Genomics, 11, 133-164.
46. Wu, X., Li, Y., Crise, B., and Burgess, S. M. (2003). Transcription start regions in the human genome are favored targets for MLV integration. Science, 300, 1749-1751.
47. Xia, H., Mao, Q., Paulson, H. L., and Davidson, B. L. (2002). siRNA-mediated gene silencing in vitro and in vivo. Nature Biotechnology, 20, 1006-1010.