Solid-phase synthesis of complex and pharmacologically interesting heterocycles

Current Opinion in Drug Discovery and Development

Volumn 12, Issue 6, 2009, Pages 798-810

  Nielsen, Thomas E ^a   Meldal, Morten ^b  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b CARLSBERG LABORATORY   (Denmark)

Author keywords

Combinatorial chemistry; Heterocycle; N acyliminium chemistry; Pictet Spengler reaction; Solid phase synthesis

Indexed keywords

ALDEHYDE; AMIDE; BENZODIAZEPINE DERIVATIVE; BETA LACTAM; ELECTROPHILE; HETEROCYCLIC COMPOUND; IMIDAZOQUINOLINE DERIVATIVE; INDOLOQUINOLINE DERIVATIVE; LACTAM; NATURAL PRODUCT; OXAZOLINE DERIVATIVE; OXINDOLE; PYRROLIDINE DERIVATIVE;

ACYLATION; ALDOL REACTION; ALKYLATION; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CYCLIZATION; CYCLOADDITION; DIASTEREOISOMER; DRUG DNA BINDING; DRUG SCREENING; MANNICH REACTION; MICHAEL ADDITION; MOLECULAR INTERACTION; OXIDATION; PICTET SPENGLER REACTION; POLYMERIZATION; REVIEW; RING CLOSING METATHESIS; SOLID PHASE SYNTHESIS; STAUDINGER REACTION; STEREOCHEMISTRY; SUBSTITUTION REACTION;

CATALYSIS; CHEMISTRY, PHARMACEUTICAL; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIZATION; HETEROCYCLIC COMPOUNDS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 70350749437     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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