Combinatorial solid-phase synthesis of 6-hydroxy-1,2,3,4-tetrahydro-β- carbolines from L-5-hydroxytryptophan

Journal of Combinatorial Chemistry

Volumn 7, Issue 3, 2005, Pages 458-462

  Danieli, Bruno ^a   Giovanelli, Paola ^a   Lesma, Giordano ^a   Passarella, Daniele ^a   Sacchetti, Alessandro ^a   Silvani, Alessandra ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOLINE DERIVATIVE; POLYSTYRENE DERIVATIVE; RESIN; TRYPTOPHAN DERIVATIVE;

ARTICLE; COMBINATORIAL CHEMISTRY; COMBINATORIAL LIBRARY; DRUG SYNTHESIS; PICTET SPENGLER REACTION; POLYMERIZATION; REACTION OPTIMIZATION; SOLID PHASE SYNTHESIS;

5-HYDROXYTRYPTOPHAN; ALKALOIDS; CARBOLINES; CHEMISTRY, PHARMACEUTICAL; COMBINATORIAL CHEMISTRY TECHNIQUES; MOLECULAR STRUCTURE; POLYSTYRENES;

EID: 20044362033     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc049881m     Document Type: Article

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34. We found that this procedure was necessary in order to preserve the stability of the final products, especially in the cases of the ester derivatives.