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Volumn 2, Issue 20, 2000, Pages 3075-3078

Solid-phase synthesis of 1,2,3,4-tetrahydro-β-carboline-containing peptidomimetics

Author keywords

[No Author keywords available]

Indexed keywords

CARBOLINE DERIVATIVE; PEPTIDE; TRYPTOLINE; TRYPTOPHAN;

EID: 0034609697     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol006209z     Document Type: Article
Times cited : (34)

References (48)
  • 1
    • 33646449394 scopus 로고    scopus 로고
    • For recent reviews in solid-phase organic synthesis, see: (a) Lorsbach, B. A.; Kurth, M. J. Chem. Rev. 1999, 99, 1549-1581.
    • (1999) Chem. Rev. , vol.99 , pp. 1549-1581
    • Lorsbach, B.A.1    Kurth, M.J.2
  • 5
    • 0033156688 scopus 로고    scopus 로고
    • For recent reviews in combinatorial chemistry, see: (a) Dolle, R. E.; Nelson, K. H. J. Comb. Chem. 1999, 1, 235-282.
    • (1999) J. Comb. Chem. , vol.1 , pp. 235-282
    • Dolle, R.E.1    Nelson, K.H.2
  • 38
    • 0001926444 scopus 로고
    • Gross, E., Meienhofer, J., Eds.; Academic Press: New York
    • Barany, G.; Merrifield, R. B. In The Peptide; Gross, E., Meienhofer, J., Eds.; Academic Press: New York, 1979; Vol. 2, p 1.
    • (1979) The Peptide , vol.2 , pp. 1
    • Barany, G.1    Merrifield, R.B.2
  • 40
    • 85037500859 scopus 로고    scopus 로고
    • note
    • 2 (3 × 2 mL). If the ninhydrin test showed a positive result, then the procedure was repeated. The resin was used directly for the next step of the reaction. Final products were cleaved from the resin with TFA/water (95:5).
  • 42
    • 85037514954 scopus 로고    scopus 로고
    • 2O). Gradient: 10% to 100% B within 15 min. UV monitoring at 220 nm.
    • 2O). Gradient: 10% to 100% B within 15 min. UV monitoring at 220 nm.
  • 43
    • 85037505145 scopus 로고    scopus 로고
    • LC-MS was performed on a Hewlett-Packard 1100 system
    • LC-MS was performed on a Hewlett-Packard 1100 system.
  • 44
    • 85037503066 scopus 로고    scopus 로고
    • 6, 300 MHz), δ 11.1, 11.2 (s, 1H), 7.0-7.6 (m, 4H), 4.7-4.9 (m, 1H), 4.1-4.3 (m, 1H), 3.2-3.4 (m, 2H), 2.9-3.2 (m, 2H)
    • 6, 300 MHz), δ 11.1, 11.2 (s, 1H), 7.0-7.6 (m, 4H), 4.7-4.9 (m, 1H), 4.1-4.3 (m, 1H), 3.2-3.4 (m, 2H), 2.9-3.2 (m, 2H).
  • 45
    • 85037503028 scopus 로고    scopus 로고
    • 1H NMR analysis of the THBC core 7j indicated that the diastereomeric ratio is approximately 1:1 in the mixture
    • 1H NMR analysis of the THBC core 7j indicated that the diastereomeric ratio is approximately 1:1 in the mixture.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.