Combination of MafA, PDX-1 and NeuroD is a useful tool to efficiently induce insulin-producing surrogate β-cells

Current Medicinal Chemistry

Volumn 16, Issue 24, 2009, Pages 3144-3151

  Kaneto, Hideaki ^a   Matsuoka, Taka Aki ^a   Katakami, Naoto ^a   Matsuhisa, Munehide ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

cell differentiation; MafA; NeuroD; PDX 1; Surrogate cells

Indexed keywords

ADENOVIRUS VECTOR; HYBRID PROTEIN; MESSENGER RNA; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 3; PROTEIN P300; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR PDX 1 PROTEIN VP16 FUSION PROTEIN; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HOMEODOMAIN PROTEIN; INSULIN; INSULIN PROMOTER FACTOR 1; NERVE PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR MAF;

DIABETES MELLITUS; DRUG POTENTIATION; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HORMONAL REGULATION; HUMAN; INSULIN SYNTHESIS; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; VIRAL GENE DELIVERY SYSTEM; ANIMAL; BIOSYNTHESIS; CELL DIFFERENTIATION; CYTOLOGY; METABOLISM; MOUSE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; HOMEODOMAIN PROTEINS; INSULIN; INSULIN-SECRETING CELLS; MAF TRANSCRIPTION FACTORS, LARGE; MICE; NERVE TISSUE PROTEINS; TRANS-ACTIVATORS;

EID: 70350741391     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986709788802980     Document Type: Review

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