The basic helix-loop-helix protein beta2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells

Genes and Development

Volumn 12, Issue 6, 1998, Pages 820-830

  Mutoh, Hiroyuki ^a   Naya, Francisco J ^b,c   Tsai, Ming Jer ^b   Leiter, Andrew B ^a  

^a TUFTS MEDICAL CENTER   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

BETA2; Enteroendocrine; Intestine; NeuroD; P300; Transcription factor

Indexed keywords

HELIX LOOP HELIX PROTEIN; SECRETIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; ENZYME ACTIVATION; GROWTH REGULATION; HUMAN; HUMAN CELL; INTESTINE CRYPT; INTESTINE EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; REGENERATION; STEM CELL; TRANSCRIPTION REGULATION;

ANIMALIA; RODENTIA;

EID: 0032521448     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.6.820     Document Type: Article

References (36)

1. Ahlgren, U., S.L. Pfaff, T.M. Jessell, T. Edlund, and H. Edlund. 1997. Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. Nature 385: 257-260.
2. Arany, Z., L.E. Huang, R. Eckner, S. Bhattacharya, C. Jiang, M.A. Goldberg, H.F. Bunn, and D.M. Livingston. 1996. An essential role for p300/CBP in the cellular response to hypoxia. Proc. Natl. Acad. Sci. 93: 12969-12973.
3. Arias, J., A.S. Alberts, P. Brindle, F.X. Claret, T. Smeal, M. Karin, J. Feramisco, and M. Montminy. 1994. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature 370: 226-229.
4. Avantaggiati, M.L., M. Carbone, A. Graessmann, Y. Nakatani, B. Howard, and A.S. Levine. 1996. The SV40 large T antigen and adenovirus E1a oncoproteins interact with distinct isoforms of the transcriptional co-activator, p300. EMBO J. 15: 2236-2246.
5. Bhattacharya, S., R. Eckner, S. Grossman, E. Oldread, Z. Arany, A. D'Andrea, and D.M. Livingston. 1996. Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature 383: 344-347.
6. Chakravarti, D., V.J. LaMorte, M.C. Nelson, T. Nakajima, I.G. Schulman, H. Juguilon, M. Montminy, and R.M. Evans. 1996. Role of CBP/P300 in nuclear receptor signalling. Nature 383: 99-103.
7. Chrivia, J.C., R.P. Kwok, N. Lamb, M. Hagiwara, M.R. Montminy, and R.H. Goodman. 1993. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365: 855-859.
8. Dai, P., H. Akimaru, Y. Tanaka, D. Hou, T. Yasukawa, C. Kanei-Ishii, T. Takahashi, and S. Ishii. 1996. CBP as a transcriptional coactivator of c-Myb. Genes &. Dev. 10: 528-540.
9. Eckner, R., M.E. Ewen, D. Newsome, M. Gerdes, J.A. DeCaprio, J.B. Lawrence, and D.M. Livingston. 1994. Molecular cloning and functional analysis of the adenovirus-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes & Dev. 8: 869-884.
10. Eckner, R., J.W. Ludlow, N.L. Lill, E. Oldread, Z. Arany, N. Modjtahedi, J.A. DeCaprio, D.M. Livingston, and J.A. Morgan. 1996a. Association of p300 and CBP with simian virus 40 large T antigen. Mol. Cell. Biol. 16: 3454-3464.
11. Eckner, R., T.-P. Yao, E. Oldread, and D.M. Livingston. 1996b. Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes & Dev. 10: 2478-2490.
12. El-Deiry, W.S., T. Tokino, T. Waldman, J.D. Oliner, V.E. Velculescu, M. Burrell, D.E. Hill, E. Healy, J.L. Rees, S.R. Hamilton, K.W. Kinzler, and B. Vogelstein. 1995. Topological control of p21 expression in normal and neoplastic tissues. Cancer Res. 55: 2910-2919.
13. Halevy, O., B.G. Novitch, D.B. Spicer, S.X. Skapek, J. Rhee, G.J. Hannon, D. Beach, and A.B. Lassar. 1995. Correlation of terminal cell cycle arrest of skeletal muscle with induction fo p21 by MyoD. Science 267: 1018-1021.
14. Hall, P.A., P.J. Coates, B. Ansari, and D. Hopwood. 1994. Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis. J. Cell Sci. 107: 3569-3577.
15. Inokuchi, H., S. Fujimoto, T. Hattori, and K. Kawai. 1985. Tritiated thymidine radioautographic study on the origin and renewal of secretin cells in the rat duodenum. Gastroenterology 89: 1014-1020.
16. Jonsson, J., U. Ahlgren, T. Edlund, and H. Edlund. 1995. IPF1, a homeodomain protein with a dual function in pancreas development. Int. J. Dev. Biol. 39: 789-798.
17. Kamei, Y., L. Xu, T. Heinzel, J. Torchia, R. Kurokawa, B. Gloss, S.C. Lin, R.A. Heyman, D.W. Rose, C.K. Glass, and M.G. Rosenfeld. 1996. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85: 403-414.
18. Kwok, R.P., J.R. Lundblad, J.C. Chrivia, J.P. Richards, H.P. Bachinger, R.G. Brennan, S.G. Roberts, M.R. Green, and R.H. Goodman. 1994. Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370: 223-226.
19. Lee, J., K.M. Galvin, R.H. See, R. Eckner, D. Livingston, E. Moran, and Y. Shi. 1995a. Relief of YY1 transcriptional repression by adenovirus E1A-associated protein p300. Genes & Dev. 9: 1188-1198.
20. Lee, J.E., S.M. Hollenberg, L. Snider, D.L. Turner, N. Lipnick, and H. Weintraub. 1995b. Conversion of Xenopus ectoderm into neurons by neuroD, a basic helix-loop-helix protein. Science 268: 836-844.
21. Lee, J.S., R.H. See, T. Deng, and Y. Shi. 1996a. Adenovirus E1A downregulates cJun-and JunB-mediated transcription by targeting their coactivator p300. Mol. Cell. Biol. 16: 4312-4326.
22. Lee, J.S., X. Zhang, and Y. Shi. 1996b. Differential interactions of the CREB/ATF family of transcription factors with p300 and adenovirus E1A. J. Biol. Chem. 271: 17666-17674.
23. Lopez, M.J., B.H. Upchurch, G. Rindi, and A.B. Leiter. 1995. Studies in transgenic mice reveal potential relationships between secretin-producing cells and other endocrine cell types. J. Biol. Chem. 270: 885-891.
24. Missero, C., E. Calautti, R. Eckner, J. Chin, L.H. Tsai, D.M. Livingston, and G.P. Dotto. 1995. Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc. Natl. Acad. Sci. 92: 5451-5455.
25. Mutoh, H., B. Fung, F. Naya, M.-J. Tsai, J. Nishitani, and A.B. Leiter. 1997. The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression. Proc. Natl. Acad. Sci. 94: 3560-3564.
26. Naya, F.J., C.M.M. Stellrecht, and M.-J. Tsai. 1995. Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes & Dev. 9: 1009-1019.
27. Naya, F.J., H. Huang, Y. Qiu, H. Mutoh, F. DeMayo, A.B. Leiter, and M.-J. Tsai. 1997. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice. Genes & Dev. 11: 2323-2334.
28. Perkins, N.D., L.K. Felzien, J.C. Betts, K. Leung, D.H. Beach, and G.J. Nabel. 1997. Regulation of NF-κB by cyclin dependent kinases associated with the p300 coactivator. Nature 275: 523-527.
29. Puri, P.L., M.L. Avantaggiati, C. Balsano, N. Sang, A. Graessmann, A. Giordano, and M. Levrero. 1997. p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription. EMBO J. 16: 369-383.
30. Sartorelli, V., J. Huang, Y. Hamamori, and L. Kedes. 1997. Molecular mechanisms of myogenic coactivation by p300: Direct interaction. Mol. Cell. Biol. 17: 1010-1026.
31. Scaglia, L., C.J. Cahill, D.T. Finegood, and S. Bonner-Weir. 1997. Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat. Endocrinology 138: 1736-1741.
32. Sosa-Pineda, B., K. Chowdhury, M. Torres, G. Oliver, and P. Gruss. 1997. The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature 386: 399-402.
33. St-Onge, L., B. Sosa-Pineda, K. Chowdhury, A. Mansouri, and P. Gruss. 1997. Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas. Nature 387: 406-409.
34. Wang, J. and K. Walsh. 1996. Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science 273: 359-361.
35. Yuan, W., G. Condorelli, M. Caruso, A. Felsani, and A. Giordano. 1996. Human p300 protein is a coactivator for the transcription factor MyoD. J. Biol. Chem. 271: 9009-9013.
36. Zhang, J.J., U. Vinkemeier, W. Gu, D. Chakvravarti, C. Horvath, and J.E. Darnell. 1996. Two contact regions between Stat1 and CBP/p300 in Interferon γ signalling. Proc. Natl. Acad. Sci. 93: 15092-15096.