A robotic system for F18 -FMISO PET-guided intratumoral p O2 measurements

Medical Physics

Volumn 36, Issue 11, 2009, Pages 5301-5309

  Chang, Jenghwa ^a,e   Wen, Bixiu ^a   Kazanzides, Peter ^b   Zanzonico, Pat ^a   Finn, Ronald D ^a   Fichtinger, Gabor ^b,c   Ling, C Clifton ^a,d  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Johns Hopkins University   (United States)

^c QUEEN S UNIVERSITY   (Canada)

^d VARIAN MEDICAL SYSTEMS   (United States)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hypoxia; Image guidance; Po2 measurement; Robot; Small animal imaging

Indexed keywords

CURVE FITTING; MEDICAL IMAGING; OXYGEN; POSITRON EMISSION TOMOGRAPHY; PROBES; RATS; ROBOTICS; ROBOTS;

CORRELATION COEFFICIENT; HYPOXIA; IMAGE GUIDANCES; MEASUREMENT POINTS; PEARSON COEFFICIENT; SMALL ANIMAL IMAGING; SMALL ANIMAL PET SCANNERS; TEMPORAL FLUCTUATION;

TUMORS;

1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL F 18; 1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL; DRUG DERIVATIVE; MISONIDAZOLE; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; IMAGE ANALYSIS; IMMUNOFLUORESCENCE TEST; NONHUMAN; OXYGEN TENSION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; RAT; ROBOTICS; THREE DIMENSIONAL IMAGING; TUMOR LOCALIZATION; TUMOR XENOGRAFT; ALGORITHM; ANIMAL; CELL HYPOXIA; EXPERIMENTAL NEOPLASM; FIBER OPTICS; IMMUNOHISTOCHEMISTRY; INSTRUMENTATION; METABOLISM; METHODOLOGY; NUDE RAT; PATHOLOGY; TUMOR CELL LINE;

ANIMALIA; RATTUS; RODENTIA;

ALGORITHMS; ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; FIBER OPTIC TECHNOLOGY; IMAGING, THREE-DIMENSIONAL; IMMUNOHISTOCHEMISTRY; MISONIDAZOLE; NEOPLASMS, EXPERIMENTAL; OXYGEN; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, NUDE; ROBOTICS;

EID: 70350710475     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.3239491     Document Type: Article

References (52)

1. M. Hockel, P. G. Knapstein, and J. Kutzner, " A novel combined operative and radiotherapeutic treatment approach for recurrent gynecologic malignant lesions infiltrating the pelvic wall.," Surg. Gynecol. Obstet. 173, 297-302 (1991).
2. P. Vaupel, " Oxygenation of human tumors: Evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements.," Cancer Res. 51, 3316-3322 (1991).
3. C. N. Coleman, " Hypoxia in tumors: A paradigm for the approach to biochemical and physiologic heterogeneity.," J. Natl. Cancer Inst. 80, 310-317 (1988). 10.1093/jnci/80.5.310
4. M. Hockel, " Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix.," Cancer Res. 56, 4509-4515 (1996).
5. M. Hockel, " Tumor oxygenation: A new predictive parameter in locally advanced cancer of the uterine cervix.," Gynecol. Oncol. 51, 141-149 (1993). 10.1006/gyno.1993.1262
6. M. Nordsmark, " Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p53 mutations.," Br. J. Cancer 84, 1070-1075 (2001). 10.1054/bjoc.2001.1728 (Pubitemid 32448504)
7. M. Nordsmark, M. Overgaard, and J. Overgaard, " Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck.," Radiother. Oncol. 41, 31-39 (1996).
8. P. L. Olive, J. P. Banath, and C. Aquino-Parsons, " Measuring hypoxia in solid tumours-Is there a gold standard?," Acta Oncol. 40, 917-923 (2001). 10.1080/02841860152708189 (Pubitemid 34098477)
9. P. Stadler, " Influence of the hypoxic subvolume on the survival of patients with head and neck cancer.," Int. J. Radiat. Oncol., Biol., Phys. 44, 749-754 (1999).
10. J. Chen, " Expression of carbonic anhydrase 9 at the invasion front of gastric cancers.," Gut 54, 920-927 (2005). 10.1136/gut.2004.047340 (Pubitemid 40873901)
11. J. L. Spivak, " The anaemia of cancer: Death by a thousand cuts.," Nat. Rev. Cancer 5, 543-555 (2005). 10.1038/nrc1648 (Pubitemid 40942830)
12. K. K. To, " Genetic instability: The dark side of the hypoxic response.," Cell Cycle 4, 881-882 (2005).
13. J. Bussink, " Effects of nicotinamide and carbogen on oxygenation in human tumor xenografts measured with luminescense based fiber-optic probes.," Radiother. Oncol. 57, 21-30 (2000). 10.1016/S0167-8140(00)00275-9 (Pubitemid 30734319)
14. D. R. Collingridge, " Measurement of tumor oxygenation: A comparison between polarographic needle electrodes and a time-resolved luminescence-based optical sensor.," Radiat. Res. 147, 329-334 (1997). 10.2307/3579340 (Pubitemid 27114389)
15. J. R. Griffiths and S. P. Robinson, " The OxyLite: A fibre-optic oxygen sensor.," Br. J. Radiol. 72, 627-630 (1999).
16. W. K. Young, B. Vojnovic, and P. Wardman, " Measurement of oxygen tension in tumours by time-resolved fluorescence.," Br. J. Cancer Suppl. 27, S256-S259 (1996).
17. 2 electrode measurements. Influence of tumour volume and carbogen breathing.," Acta Oncol. 41, 304-312 (2002). 10.1080/02841860260088863 (Pubitemid 34833056)
18. S. S. Foo, " Functional imaging of intratumoral hypoxia.," Mol. Imaging Biol. 6, 291-305 (2004). 10.1016/j.mibio.2004.06.007 (Pubitemid 39263636)
19. W. J. Koh, " Imaging of hypoxia in human tumors with [F-18]fluoromisonidazole.," Int. J. Radiat. Oncol., Biol., Phys. 22, 199-212 (1992).
20. 2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models.," Int. J. Radiat. Oncol., Biol., Phys. 61, 1493-1502 (2005).
21. J. A. Raleigh, " Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours.," Br. J. Cancer 56, 395-400 (1987).
22. F. A. Howe, " Issues in flow and oxygenation dependent contrast (FLOOD) imaging of tumours.," NMR Biomed. 14, 497-506 (2001). 10.1002/nbm.716 (Pubitemid 33150238)
23. V. D. Kodibagkar, " Novel 1H NMR approach to quantitative tissue oximetry using hexamethyldisiloxane.," Magn. Reson. Med. 55, 743-748 (2006). 10.1002/mrm.20826
24. J. M. Brown, " In vivo evaluation of the radiosensitizing and cytotoxic properties of newly synthesized electron-affinic drugs.," Br. J. Cancer Suppl. 37, 206-211 (1978).
25. J. G. Rajendran and K. A. Krohn, " Imaging hypoxia and angiogenesis in tumors.," Radiol. Clin. North Am. 43, 169-187 (2005). 10.1016/j.rcl.2004.08.004 (Pubitemid 40326567)
26. A. R. Padhani, " Imaging oxygenation of human tumours.," Eur. Radiol. 17, 861-872 (2007). 10.1007/s00330-006-0431-y (Pubitemid 46772763)
27. W. J. Koh, " Evaluation of oxygenation status during fractionated radiotherapy in human nonsmall cell lung cancers using [F-18]fluoromisonidazole positron emission tomography.," Int. J. Radiat. Oncol., Biol., Phys. 33, 391-398 (1995).
28. D. Thorwarth, " Combined uptake of [18F]FDG and [18F]FMISO correlates with radiation therapy outcome in head-and-neck cancer patients.," Radiother. Oncol. 80, 151-156 (2006). 10.1016/j.radonc.2006.07. 033 (Pubitemid 44301544)
29. J. M. Arbeit, " Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy.," Int. J. Radiat. Biol. 82, 699-757 (2006). 10.1080/ 09553000601002324 (Pubitemid 44832019)
30. M. Nordsmark, " Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas.," Radiother. Oncol. 67, 35-44 (2003). 10.1016/S0167-8140(03)00010-0 (Pubitemid 36570438)
31. L. Bentzen, " Tumour oxygenation assessed by 18F-fluoromisonidazole PET and polarographic needle electrodes in human soft tissue tumours.," Radiother. Oncol. 67, 339-344 (2003). 10.1016/S0167-8140(03)00081-1 (Pubitemid 36831089)
32. J. M. Brown, " Evidence for acutely hypoxic cells in mouse tumours, and a possible mechanism of reoxygenation.," Br. J. Radiol. 52, 650-656 (1979). 10.1259/0007-1285-52-620-650
33. D. Stoianovici, " MRI stealth' robot for prostate interventions.," Minimally Invasive Ther. Allied Technol. 16, 241-248 (2007). 10.1080/13645700701520735 (Pubitemid 47343471)
34. Y. Barzilay, " Miniature robotic guidance for spine surgery-Introduction of a novel system and analysis of challenges encountered during the clinical development phase at two spine centres.," Int. J. Med. Robotics Comput Assist Surg 2, 146-153 (2006). 10.1002/rcs.90 (Pubitemid 44580033)
35. K. Cleary, " Precision placement of instruments for minimally invasive procedures using a needle driver' robot.," Int. J. Med. Robotics Comput Assist Surg 1, 40-47 (2005). 10.1002/rcs.40
36. S. P. DiMaio, " Robot-assisted needle placement in open MRI: System architecture, integration and validation.," Comput. Aided Surg. 12, 15-24 (2007). 10.1080/10929080601168254 (Pubitemid 46280016)
37. J. R. Adler, Jr., " Image-guided robotic radiosurgery.," Neurosurgery 44, 1299-1307 (1999). 10.1097/00006123-199906000-00079 (Pubitemid 29252751)
38. P. Kazanzides, " Development of an image-guided robot for small animal research.," Comput. Aided Surg. 12, 357-365 (2007). 10.1080/10929080701732538 (Pubitemid 350232916)
39. A. C. Waspe, " Design, calibration and evaluation of a robotic needle-positioning system for small animal imaging applications.," Phys. Med. Biol. 52, 1863-1878 (2007). 10.1088/0031-9155/52/7/007 (Pubitemid 46646351)
40. A. Ayadi, " Fully automated image-guided needle insertion: Application to small animal biopsies.," Conference Proceedings IEEE Engineering Medicine and Biology Society (IEEE, Lyon, France, 2007), Vol. 2007, pp. 194-197.
41. P. Zanzonico, " Animal-specific positioning molds for registration of repeat imaging studies: Comparative microPET imaging of F18-labeled fluoro-deoxyglucose and fluoro-misonidazole in rodent tumors.," Nucl. Med. Biol. 33, 65-70 (2006). 10.1016/j.nucmedbio.2005.07.011 (Pubitemid 43184079)
42. A. Cherif, " Rapid synthesis of 3-[18F]fluoro-1-(2′ -nitro- 1′ -imidazolyl)-2-propanol ([18F]fluoromisonidazole).," Pharm. Res. 11, 466-469 (1994). 10.1023/A:1018937709835 (Pubitemid 24117371)
43. D. J. Yang, " Development of F-18-labeled fluoroerythronitroimidazole as a PET agent for imaging tumor hypoxia.," Radiology 194, 795-800 (1995).
44. 2) using the OxyLite system in R3327-AT tumors under isoflurane anesthesia.," Radiat. Res. 166, 512-518 (2006). 10.1667/RR3602.1 (Pubitemid 44353435)
45. F. He, " Noninvasive molecular imaging of hypoxia in human xenografts: Comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers.," Cancer Res. 68, 8597-8606 (2008). 10.1158/0008-5472.CAN-08-0677
46. J. S. Rasey, " Characteristics of the binding of labeled fluoromisonidazole in cells in vitro.," Radiat. Res. 122, 301-308 (1990). 10.2307/3577760 (Pubitemid 20214420)
47. L. I. Cardenas-Navia, T. W. Secomb, and M. W. Dewhirst, " Effects of fluctuating oxygenation on tirapazamine efficacy: Theoretical predictions.," Int. J. Radiat. Oncol., Biol., Phys. 67, 581-586 (2007).
48. M. Zhang, " Accuracy and reproducibility of tumor positioning during prolonged and multi-modality animal imaging studies.," Phys. Med. Biol. 53, 5867-5882 (2008). 10.1088/0031-9155/53/20/021
49. D. Thorwarth, " A kinetic model for dynamic [18F]-FMISO PET data to analyse tumour hypoxia.," Phys. Med. Biol. 50, 2209-2224 (2005). 10.1088/0031-9155/50/10/002 (Pubitemid 40767811)
50. H. Cho, " Noninvasive multimodality imaging of the tumor microenvironment: Registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia.," Neoplasia 11, 247-259 (2009).
51. J. J. Casciari, M. M. Graham, and J. S. Rasey, " A modeling approach for quantifying tumor hypoxia with [F-18]fluoromisonidazole PET time-activity data.," Med. Phys. 22, 1127-1139 (1995). 10.1118/1.597506
52. W. Wang, " Evaluation of a compartmental model for estimating tumor hypoxia via FMISO dynamic PET imaging.," Phys. Med. Biol. 54, 3083-3099 (2009). 10.1088/0031-9155/54/10/008