Noninvaise multimodality imaging of the tumor microenvironment:tegistered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia1,2

Neoplasia

Volumn 11, Issue 3, 2009, Pages 247-259

  HyungJoon, Cho ^a   Ackurstaff, Ellen ^a   Carlin, Sean ^a   Lupu, Mihaela E ^a   Ya, Wang ^a   Rizwan, Asif ^a   O'Donoghue, Joseph ^a   Clifton Ling, C ^a   Humm, John L ^a   Zamonico, Pal B ^a   Koutcher, Jason A ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL F 18; GADOLINIUM PENTETATE; 1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL; DIAGNOSTIC AGENT; DRUG DERIVATIVE; MISONIDAZOLE; NITROIMIDAZOLE DERIVATIVE; PIMONIDAZOLE; RADIOPHARMACEUTICAL AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; CONTRAST ENHANCEMENT; DIAGNOSTIC VALUE; DRUG UPTAKE; HYPOXIA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSTATE TUMOR; RAT; STEREOTACTIC PROCEDURE; TUMOR DIAGNOSIS; TUMOR VASCULARIZATION; ANIMAL; CELL HYPOXIA; DISEASE MODEL; IMAGE PROCESSING; MALE; METHODOLOGY; PATHOLOGY;

ANIMALS; AUTORADIOGRAPHY; CELL HYPOXIA; DISEASE MODELS, ANIMAL; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MISONIDAZOLE; NITROIMIDAZOLES; POSITRON-EMISSION TOMOGRAPHY; PROSTATIC NEOPLASMS; RADIOPHARMACEUTICALS; RATS;

EID: 62549157852     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.81360     Document Type: Article

References (38)

1. Chaudary N and Hill RP (2006). Hypoxia and metastasis in breast cancer. Breast Dis 26, 55-64.
2. Hockel M, Schlenger K, Mitze M, Schaffer U, and Vaupel P (1996). Hypoxia and radiation response in human tumors. Semin Radiat Oncol 6, 3-9.
3. Vaupel P, Mayer A, Briest S, and Hockel M (2005). Hypoxia in bteast cancer: role of blood flow, oxygen diffusion distances, and anemia in the development of oxygen depletion. Adv Exp Med Biol 566, 333-342.
4. Menon C and Fraker DL (2005). Tumor oxygenation status as a prognostic matket. Cancer Lett 221, 225-235.
5. Dachs GU and Chaplin DJ (1998). Microenvironmental control of gene expres sion: implications for tumor angiogenesis, progression, and metastasis. Semin Radiat Oncol 8, 208-216.
6. Secomb TW, Hsu R, Braun RD, Ross JR, Gross JF, and Dewhirst MW (1998). Theotetical simulation of oxygen transport to tumors by three-dimensional networks of microvessels. Adv Exp Med Biol 454, 629-634.
7. Haroon ZA, Peters KG, Greenberg CS, and Dewhirst MW (1998). Angiogenesis and oxygen ttanspott in solid tumots. In BATeicher (Ed.). AntiangiogenicAgents in Cancer Therapy, Totowa, NJ: Humana Press Inc., pp. 3-21.
8. Neeman M, Provenzale JM, and Dewhirst MW (2001). Magnetic resonance imaging applications in the evaluation of tumor angiogenesis. Semin Radiat Oncol 11, 70-82.
9. Koh WJ, Rasey JS, Evans ML, Grierson JR, Lewellen TK, Graham MM, Krohn KA, and Griffin TW (1992). Imaging of hypoxia in human tumors with [F-18] fluoromisonidazole. Int J Radiat Oncol Biol Phys 22, 199-212.
10. Casciari JJ, Graham MM, and Rasey JS (1995). A modeling approach for quan tifying tumor hypoxia with [F-l 8]fluotomisonidazole PET time-activity data. Med Phys 22, 1127-1139.
11. Serganova I, HunimJ, Ling C, and Blasberg R (2006). Tumor hypoxia imaging. Clin Cancer Res 12, 5260-5264.
12. l8F-fluoromisonidazole. Semin Nuel Med 37, 451-461.
13. Tofts PS (1997). Modeling tracer kinetics in dynamic Gd-DTPA MR imaging. J Magn Reson Imaging,91-101.
14. Kuhl CK, Mielcareck P, Klaschik S, Leutner C, Wardelmann E, Gieseke J, and Schild HH (1999). Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions? Radiobgy211, 101-110.
15. Ogawa S, Lee TM, Kay AR, and Tank DW (1990). Brain magnetic resonance imaging with conttast dependent on blood oxygenation. Proc Natl Acad Sci USA 87, 9868-9872.
16. Sotak CH, Hees PS, Huang HN, Hung MH, Krespan CG, and Raynolds S (1993). A new perfluorocarbon for use in fluorine-19 magnetic resonance imaging and spectroscopy. Magn Reson Med 29, 188-195.
17. 19F magnetic resonance spectroscopy and chemical shift imaging of tri-fluoro-nitroimidazole as a potential hypoxia reporter in solid tumors. Clin Cancer Res 13, 3738-3747.
18. Mason RP, Antich PP, Babcock EE, Constantinescu A, Peschke P, and Hahn EW (1994). Non-invasive determination of tumor oxygen tension and local vari ation with growth. Int J Radiat Oncol Biol Phys 29, 95-103.
19. HeQ, Shungu DC, van Zijl PC, BhujwallaZM, andGlicksonJD (1995). Single-scan in vivo lactate editing with complete lipid and water suppression by selective multiple-quantum-coherence transfer (Sel-MQC) with application to tumors. J Magn Reson B 106, 203-211.
20. Jue T, Arias-Mendoza F, Gonnella NC, Shulman GI, and Shulman RG (1985). A lH NMR technique for observing metabolite signals in the spectrum of perfused liver. Proc Natl Acad Sci USA 82, 5246-5249.
21. Hylton N (2006). Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker. J Clin Oncol 24, 3293-3298
22. Egeland TA, Gaustad JV, Benjaminsen IC, Hedalen K, Mathiesen B, and Rofstad EK (2008). Assessment of fraction of hypoxic cells in human tumor xenografts with necrotic regions by dynamic contrast-enhanced MRI. Radiat Res 169, 689-699.
23. Isaacs JT, Isaacs WB, Feitz WF, and Scheres J (1986). Establishment and char-acterization of seven Dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers. Pros tate 9, 261-281
24. Euhus DM, Hudd C, LaRegina MC, and Johnson FE (1986). Tumor measure ment in the nude mouse. J Surg Oncol 31, 229-234.
25. Humm JL, Ballon D, Hu YC, Ruan S, Chui C, Tulipano PK, Erdi A, Koutcher J, Zakian K, Urano M, et al. (2003). A stereotactic method for the three-dimensional registration of multi-modality biologic images in animals: NMR, PET, histology, and autoradiography. Med Phys 30, 2303-2314.
26. Zhang M, Huang M, Le C, Zanzonico PB, Claus F, Kolbert KS, Martin K, Ling CC, Koutcher JA, and Humm JL (2008). Accuracy and reproducibility of tu-mor positioning during prolonged and multi-modality animal imaging studies. Phys Med Biol 53, 5867-5882.
27. Zanzonico P, CampaJ, Polycarpe-HolmanD, ForsterG, Finn R, Larson S, Humm J, and Ling C (2006). Animal-specific positioning molds for registration of repeat imaging studies: comparative microPET imaging of FISTabeled fluoro-deoxyglucose and fluoro-misonidazole in rodent tumors. Nucl Med Biol 33, 65-70.
28. Engelhardt EL, Schneider RF, Seeholzer SH, Stobbe CC, and Chapman JD (2002). The synthesis and radiolabeling of 2-nitroimidazole derivatives of cyclam and their preclinical evaluation as positive markers of tumor hypoxia. J Nucl Med 43, 837-850.
29. Hoffmann U, Brix G, Knopp MV, Hess T, and Lorenz WJ (1995). Pharmacokinetic mapping of the breast: a new method for dynamic MR mammography. Magn Reson Med33, 506-514.
30. Thorwarth D, Eschmann SM, Paulsen F, and Alber M (2005). A kinetic model for dynamic [ F]-Fmiso PET data to analyse tumour hypoxia. Phys Med Biol 50, 2209-2224.
31. Thorndyke C, Meeker BE, Thomas G, Lakey WH, McPhee MS, and Chapman JD (1985). The radiation sensitivities of R3327-H and R3327-ATtat prostate adenocarcinomas.J Urol 134, 191-198.
32. Hunjan S, Zhao D, Constantinescu A, Hahn EW, Antich PP, and Mason RP (2001). Tumot oximetry: demonsttation of an enhanced dynamic mapping pro cedure using fluorine-19 echo planar magnetic resonance imaging in the Dunning prostate R3327-AT1 rat tumor. Int J Radiat Oncol Biol Phys 49, 1097-1108.
33. Catana C, Procissi D, Wu Y, Judenhofer MS, Qi J, Pichler BJ, Jacobs RE, and Cherry SR (2008). Simultaneous in vivo positron emission tomography and magnetic resonance imaging. Proc Natl Acad Sci USA 105, 3705-3710.
34. Judenhofer MS, Wehrl HF, Newport DF, Catana C, Siegel SB, Becker M, Thielscher A, Kneilling M, Lichy MR Eichner M, et al. (2008). Simultaneous PET-MRI: a new approach for functional and motphological imaging. Nat Med 14, 459-465.
35. Schlemmer HP Pichler BJ, Krieg R, and Heiss WD (2008). An integrated MR/PET system: prospective applications. Abdom Imaging.
36. Schlemmer HP, Pichler BJ, Schmand M, Burbar Z, Michel C, Ladebeck R, Jattke K, Townsend D, Nahmias C, Jacob PK, et al. (2008). Simultaneous MR/ PET imaging of the human brain: feasibility study. Radiology 248, 1028-1035.
37. 20. J Nucl Med 45, 1851-1859.
38. 18 F-fluoromisonidazole PET correlates with radia tion treatment outcome in head-and-neck cancer. BMC Cancer 5, 152.