Issues in flow and oxygenation dependent contrast (FLOOD) imaging of tumours

NMR in Biomedicine

Volumn 14, Issue 7-8, 2001, Pages 497-506

  Howe, F A ^a   Robinson, S P ^a   McIntyre, D J O ^a   Stubbs, M ^a   Griffiths, J R ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

BOLD; Carbogen; MRI; Oxygenation; Perfusion; Tumor

Indexed keywords

BLOOD; GENES; GLUCOSE; MAGNETIC RESONANCE IMAGING; METABOLISM; NITROGEN; OXYGENATORS; PH EFFECTS; TUMORS;

CALCITONIN GENE RELATED PEPTIDES (CGRP);

MEDICINE;

CALCITONIN GENE RELATED PEPTIDE; CARBOGEN; DEOXYHEMOGLOBIN; GLUCOSE; HYDRALAZINE; NICOTINAMIDE; NITROGEN; OXYGEN; VASOACTIVE AGENT;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOENERGY; BLOOD OXYGENATION; BLOOD PH; BLOOD VOLUME; CANCER THERAPY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC IMAGING; EXTRACTION; GAS; GLUCOSE BLOOD LEVEL; GLYCOLYSIS; HYPOXIA; MEASUREMENT; NONHUMAN; PARAMETER; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHYSIOLOGY; PRIORITY JOURNAL; PROLACTINOMA; RAT; SENSITIVITY AND SPECIFICITY; STIMULUS; TUMOR BLOOD FLOW; TUMOR DIAGNOSIS; TUMOR VASCULARIZATION;

ANIMALS; BLOOD PRESSURE; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE IMAGING; NEOPLASMS, EXPERIMENTAL; OXYGEN; PITUITARY NEOPLASMS; PROLACTINOMA; RATS;

EID: 0035216751     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/nbm.716     Document Type: Article

References (42)

1. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging
2. 31P MRS
3. Tumour response to hypercapnia and hyperoxia monitored by FLOOD magnetic resonance imaging
4. Flow and oxygenation dependent (FLOOD) contrast in MR imaging to monitor the response of rat tumors to carbogen breathing
5. Effects of Nicotinamide and carbogen on tumor oxygenation, blood flow, energetics and blood glucose levels
6. 2* and arterial blood gases
7. 2 breathing causes vascular collapse in some subcutaneous tumors
8. On the correlation of FLOOD/MGRE imaging and dynamic contrast agent imaging with dimeglumine gadopentate
9. 2* weighted magnetic resonance images of tumors in a rodent model
10. In vivo prediction of vascular susceptibility to vascular endothelial growth factor withdrawal: Magnetic resonance imaging of C6 rat glioma in nude mice
11. Carbogen and nicotinamide in the treatment of bladder cancer with radical radiotherapy
12. The potential for prazosin and calcitonin gene-related peptide (CGRP) in causing hypoxia in tumours
13. From hydralazine to CGRP to man?
14. Theory of NMR signal behaviour in magnetically inhomogeneous tissues: The static dephasing regime
15. Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging
16. 2* of brain parenchyma accurately reflect the combined effects of changes in arterial and cerebral venous oxygen saturation
17. MRI Measurements of cerebral deoxyhaemoglobin concentration [dHb]-correlation with near infrared spectroscopy (NIRS)
18. On the characteristics of functional magnetic resonance imaging of the brain
19. Simulataneous measurement of perfusion and oxygenation changes using a multiple gradient-echo sequence: Application to human muscle study
20. Blood flow and oxygenation of tumors in mice
21. Arteriolar oxygenation in tumor and subcutaneous arterioles: Effects of inspired air oxygen content
22. The sensitivity of magnetic resonance image signals of a rat brain to changes in the cerebral venous blood oxygenation
23. Analysis of subcutaneous angiogenesis by gradient echo magnetic resonance imaging
24. Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood
25. NMR imaging of changes in vascular morphology due to tumor angiogenesis
26. 2 changes: Simulations using a deterministic diffusion model
27. Determinants of tumor blood flow
28. Magnetic resonance spectroscopy studies on experimental murine and human tumors: Comparison of changes in phosphorus metabolism with induced changes in vascular volume
29. The radiosensitiser nicotinamide inhibits arterial vasoconstriction
30. Nicotinamide can lower tumor interstitial fluid pressure: Mechanistic and therapeutic implications
31. The effects of hyperoxic and hypercarbic gases on tumor blood flow
32. The mechanisms by which hyperbaric oxygen and carbogen improve tumor oxygenation
33. Transport of oxygen and carbon dioxide in the blood and body fluids
34. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
35. Effect of glucose on BOLD contrast in tumors during normoxia and hypoxia
36. 2) breathing on metabolic characteristics of Morris hepatoma 9618a
37. Noninvasive investigation of blood oxygenation dynamics of tumors by near-infrared spectroscopy
38. The Oxylite: A fibre-optic oxygen sensor
39. Analysis of subcutaneous angiogenesis by gradient echo magnetic resonance imaging
40. Correlation of magnetic resonance and oxygen microelectrode measurements of carbogen-induced changes in tumor oxygenation
41. MRI measurements correctly predict the relative effects of tumor oxygenating agents on hypoxic fraction in rodent BA1112 tumors
42. 2* with response to radiotherapy