A systematic review of experimental treatments for mitochondrial dysfunction in sepsis and multiple organ dysfunction syndrome

Free Radical Biology and Medicine

Volumn 47, Issue 11, 2009, Pages 1517-1525

  Dare, Anna J ^a   Phillips, Anthony R J ^a,b   Hickey, Anthony J R ^b   Mittal, Anubhav ^a   Loveday, Benjamin ^a   Thompson, Nichola ^a   Windsor, John A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Cytopathic hypoxia; Free radicals; Mitochondria; Multiple organ dysfunction syndrome; Sepsis

Indexed keywords

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE MAGNESIUM; AMINOGUANIDE; ANTIOXIDANT; CAFFEINE; CARNITINE; CASPASE; CYCLOSPORIN A; CYTOCHROME C; CYTOKINE; DEFEROXAMINE; GLUTATHIONE CHOLINE ESTER; MANGANESE 5,10,15,20 TETRAKIS(N ETHYLPYRIDINIUM 2 YL)PORPHYRIN; MELATONIN; MITOQUINONE; N TERT BUTYL ALPHA PHENYLNITRONE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; PYRUVIC ACID DERIVATIVE; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SKQ; SUCCINIC ACID; SYNTHETIC PEPTIDE; SZETO SCHILLER PEPTIDE; TEMPOL; THIOCTIC ACID; UBIQUINONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

BIOENERGY; CELL FUNCTION; CELL HYPOXIA; CELL ORGANELLE; CHRONIC INFLAMMATION; DEGENERATIVE DISEASE; DIAPHRAGM DISEASE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG MECHANISM; DRUG SCREENING; ENDOTOXEMIA; ENZYME ACTIVATION; EXPERIMENTAL MODEL; EXPERIMENTAL THERAPY; HEART DISEASE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HUMAN; ISCHEMIA; KIDNEY DYSFUNCTION; LIVER DYSFUNCTION; LIVER NECROSIS; MEMBRANE PERMEABILITY; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL MEMBRANE; MULTIPLE ORGAN FAILURE; NONHUMAN; ORGAN INJURY; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; SEPSIS; SEPTIC SHOCK; SINGLE DRUG DOSE; SYSTEMATIC REVIEW; TARGET CELL;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL HYPOXIA; COENZYMES; ELECTRON TRANSPORT; FREE RADICAL SCAVENGERS; HUMANS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MULTIPLE ORGAN FAILURE; OXIDATIVE STRESS; RECOVERY OF FUNCTION; SEPSIS;

EID: 70350620444     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.08.019     Document Type: Review

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