Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis

Journal of Neurochemistry

Volumn 98, Issue 4, 2006, Pages 1141-1148

  Petri, Susanne ^a,b   Kiaei, Mahmoud ^a   Damiano, Maria ^a   Hiller, Andrew ^a   Wille, Elizabeth ^a   Manfredi, Giovanni ^a   Calingasan, Noel Y ^a   Szeto, Hazel H ^a   Beal, M Flint ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Amyotrophic lateral sclerosis; Apoptosis; G93A transgenic mouse model; Mitochondria; Reactive oxygen species

Indexed keywords

ANTIOXIDANT; BIOLOGICAL MARKER; COPPER ZINC SUPEROXIDE DISMUTASE; DEXTRO ARGININE 2',6' DIMETHYLTYROSYLLYSYLPHENYLALANINAMIDE; HYDROGEN PEROXIDE; PEPTIDE DERIVATIVE; SS 31; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CELL LOSS; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG PENETRATION; DRUG TARGETING; FEMALE; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRIAL MEMBRANE; MOTOR PERFORMANCE; MOUSE; MUTANT; NERVE CELL; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SURVIVAL; THERAPY EFFECT; TRANSGENIC MOUSE; WILD TYPE;

AGING; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTIOXIDANTS; BODY WEIGHT; CELL COUNT; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; DISEASE MODELS, ANIMAL; MICE; MICE, TRANSGENIC; PEPTIDES; PSYCHOMOTOR PERFORMANCE; REACTIVE OXYGEN SPECIES; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 33746397617     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04018.x     Document Type: Article

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