Evidence for early supply independent mitochondrial dysfunction in patients developing multiple organ failure after trauma

Journal of Trauma - Injury, Infection and Critical Care

Volumn 42, Issue 3, 1997, Pages 532-536

  Cairns, Charles B ^a   Moore, Frederick A ^d   Haenel, James B ^c   Gallea, Barbara L ^e   Ortner, Joseph P ^e   Rose, Shane J ^b   Moore, Ernest E ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c DENVER HEALTH MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^e Hutchinson Technology Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXYHEMOGLOBIN;

ADULT; CLINICAL ARTICLE; CLINICAL PROTOCOL; CONFERENCE PAPER; HUMAN; MITOCHONDRIAL RESPIRATION; MULTIPLE ORGAN FAILURE; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PATIENT CARE; PATIENT MONITORING; PRIORITY JOURNAL; RESUSCITATION; TRAUMATOLOGY; TREATMENT OUTCOME;

EID: 0030989547     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/00005373-199703000-00023     Document Type: Conference Paper

References (38)

1. Moore FA, Moore EE: Evolving concepts in the pathogenesis of postinjury multiple organ failure. Chapter in Horizons in Trauma Surgery. Surg Clin North Am 75:257, 1995
2. Tilney NL, Bailey GL, Morgan AP: Sequential system failure after rupture of abdominal aortic aneurysms: An unsolved problem in postoperative care. Ann Surg 178:117, 1973
3. Eiseman B, Beart R, Norton L: Multiple organ failure. Surg Gynecol Obstet 144:323, 1977
4. Shoemaker WC, Montgomery ES, Kaplan E, et al: Physiologic patterns in surviving and nonsurviving shock patients: Use of sequential cardiorespiratory variables in defining criteria for therapeutic goals and early warning of death. Arch Surg 106:630, 1973
5. Shoemaker WC, Appel PL, Kram HB: Role of oxygen debt in the development of organ failure, sepsis and death in high-risk surgical patients. Chest 102:208, 1992
6. Shoemaker WC, Appel PL, Kram HB, et al: Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest 94:1176, 1988
7. Moore FA, Haenel JB, Moore EE, et al: Incommensurate oxygen consumption in response to maximal oxygen availability predicts postinjury multisystem organ failure. J Trauma 33:58, 1992
8. Sauaia A, Moore FA, Moore EE, et al: Early predictors of postinjury multiple organ failure. Arch Surg 129:39, 1994
9. Moore FA, Moore EE: Trauma resuscitation. In Wilmore DW, Brennen MF, Harken AH (eds): Scientific American Surgery, New York, Scientific American, 1995, Chapter 2.
10. Jobsis FF: Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science 198:1264, 1977
11. Proctor HJ, Palladino GW, Cairns CB, et al: An evaluation of perfluorochemical resuscitation after hypoxic hypotension. J Trauma 23:79, 1983
12. Moore FA, Sauaia A, Moore EE, et al: Postinjury multiple organ failure: A bimodal phenomenon. J Trauma 40:1, 1996
13. Alberts B: Energy conversion: Mitochondria and chloroplasts. In Alberts B, Bray D, Lewis J, et al. (eds): Molecular Biology of the Cell. New York, Garland Publishing, 1994, pp 676-677
14. Boyd O, Grounds RM, Bennett ED: A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high-risk surgical patients. JAMA 270:2699, 1993
15. Gattinoni L, Brazzi L, Pelosi P, et al: A trial of goal-oriented hemodynamic therapy in critically ill patients. N Engl J Med 333:1025, 1995
16. Hinds C, Watson D. Manipulating hemodynamics and oxygen transport in critically ill patients. N Engl J Med 333:1025, 1995
17. Waxman K, Annas C, Daughters K, et al: A method to determine the adequacy of resuscitation using tissue oxygen monitoring. J Trauma 36:852, 1994
18. Gletcher WM, Hopkins FG: Lactic acid in amphibian muscle. J Physiol (Lond) 35:247, 1906
19. Opie LH: Cardiac metabolism: Emergence, decline, and resurgence. Cardiovasc Res 26:721, 1992
20. Cairns CB, Filipo D, Palladino GW, et al: Direct noninvasive assessment of brain metabolism during increased intracranial pressure: Potential therapeutic vistas. J Trauma 26:863, 1986
21. Chance B, Williams GR: A method for the localization of sites for oxidative phosphorylation. Nature 176:250, 1955
22. 3 induced cellular oxidation during global ischemia. Circulation 94:8:I-362, 1996
23. Proctor HJ, Sylvia AL, Jobsis FF: Failure of brain cytochrome a,a3 redox recovery after hypoxic hypotension as determined by in vivo reflectance spectrophotometry. Stroke 13:89, 1982
24. Zhang J, Piantados CA: Mitochondrial oxidative stress after carbon monoxide hypoxia in the rat brain. J Clin Invest 90:1193, 1992
25. Boveris A, Chance B. The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134:707, 1973
26. Cross AR, Jones OTG: Enzymatic mechanisms of superoxide production. Biochim Biophys Acta 1057:281, 1991
27. Chance B, Williams G: The respiratory chain and oxidative phosphorylation. Adv Enzymol 17:65-134, 1956
28. Cairns CB, Walther JM, Harken AH, et al: Mitochondrial oxidative phosphorylation thermodynamic efficiencies reflect physiologic organ roles in the rat. Am J Physiol. In press
29. 3 during lethal endotoxemia. J Surg Res 51:382, 1991
30. Schumer W, Das D, Gupta TK, et al: Effect of endotoxemia on liver cell mitochondria in man. Ann Surg 171:875, 1970
31. Mela L: Direct and indirect effects of endotoxin on mitochondrial function. In Majde JA, Person RJ (eds): Pathophysiological Effects of Endotoxins at the Cellular Level. New York, Alan R Liss, 1981, pp 15-21
32. Cairns CB, Bensard DD, Winter CB, et al: A rapid effect of endotoxin on the myocardium. Surg Forum 43:22, 1992
33. Stadler J, Bentz BG, Harbrecht BG, et al: Tumor necrosis factor alpha inhibits hepatocyte mitochondrial respiration. Ann Surg 216:539, 1992
34. Stuehr DG, Nathan CF: Nitric oxide: A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J Exp Med 169:1543, 1989
35. Radi R, Rodriguez M, Castro L, et al: Inhibition of mitochondrial electron transport by peroxynitrite. Arch Biochem Biophys 308:89, 1994
36. Hoch RC, Rodriguez R, Manning T, et al: Effects of accidental trauma on cytokine and endotoxin production. Crit Care Med 21:839, 1993
37. Prough DS, Pollard V: Cerebral near-infrared spectroscopy: Ready for prime time? Crit Care Med 23:1624, 1995
38. Tateishi A, Maekawa T, Soejima Y, et al: Qualitative comparison of carbon dioxide-induced change in cerebral near-infrared spectroscopy versus jugular venous oxygen saturation in adults with acute brain disease. Crit Care Med 23:1734, 1995