메뉴 건너뛰기




Volumn 17, Issue 1, 2001, Pages 219-237

Cytopathic hypoxia: Mitochondrial dysfunction as mechanism contributing to organ dysfunction in sepsis

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; PEROXYNITRITE; PYRUVATE DEHYDROGENASE; UNCOUPLING PROTEIN;

EID: 0035115951     PISSN: 07490704     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0749-0704(05)70161-5     Document Type: Article
Times cited : (270)

References (96)
  • 10
    • 0029963244 scopus 로고    scopus 로고
    • Rapid reduction of nitric oxide by mitochondria, and reversible inhibition of mitochondrial respiration by nitric oxide
    • (1996) Biochem J , vol.315 , pp. 295
    • Borutaité, V.1    Brown, G.C.2
  • 19
    • 0028075423 scopus 로고
    • Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel
    • (1994) Biochem J , vol.302 , pp. 321
    • Connern, C.P.1    Halestrap, A.P.2
  • 25
    • 0029916746 scopus 로고    scopus 로고
    • The role of nitric oxide in sepsis and ARDS: Synopsis of a roundtable conference held in Brussels on 18-20 March 1995
    • (1996) Intsiv Care Med , vol.22 , pp. 158
    • Fink, M.P.1    Payen, D.2
  • 29
    • 0033615544 scopus 로고    scopus 로고
    • Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria. Evidence for intramitochondrial peroxynitrite formation
    • (1999) J Biol Chem , vol.27 , pp. 31185
    • Ghafourifar, P.1    Schenk, U.2    Klein, S.D.3
  • 34
    • 0027101755 scopus 로고
    • Tetrahydrobiopterin synthesis. An absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle
    • (1992) J Biol Chem , vol.267 , pp. 25722
    • Gross, S.S.1    Levi, R.2
  • 38
  • 42
    • 0029130793 scopus 로고
    • Breakdown of adenine nucleotides, formation of oxygen free radicals, and early markers of cellular injury in endotoxic shock
    • (1995) Eur J Surg , vol.161 , pp. 147
    • Jabs, C.M.1    Neglen, P.2    Eklof, B.3
  • 72
    • 0023118342 scopus 로고
    • Pathophysiology of acute renal failure following living Escherichia coli injection in rats: High-energy metabolism and renal functions
    • (1987) Circ Shock , vol.21 , pp. 197
    • Shimahara, Y.1    Kono, Y.2    Tanaka, J.3
  • 78
    • 0029934194 scopus 로고    scopus 로고
    • Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite
    • (1996) Circ Res , vol.78 , pp. 1051
    • Szabo, C.1    Zingarelli, B.2    Salzman, A.L.3
  • 79
    • 0032582792 scopus 로고    scopus 로고
    • Poly (ADP-ribose) synthetase activation mediates pulmonary microvascular and intestinal mucosal dysfunction in endotoxin shock
    • (1998) Life Sci , vol.63 , pp. 2133
    • Szabo, A.1    Salzman, A.L.2    Szabo, C.3
  • 85
    • 0031006460 scopus 로고    scopus 로고
    • Acidic conditions ameliorate both ATP depletion and the development of hyperpermeability in cultured Caco-2 enterocytic monolayers subjected to metabolic inhibition
    • (1997) Surgery , vol.121 , pp. 668
    • Unno, N.1    Menconi, M.J.2    Smith, M.3
  • 90
    • 0025798603 scopus 로고
    • Increased pyruvate dehydrogenase kinase activity in response to sepsis
    • (1991) Am J Physiol , vol.250
    • Vary, T.C.1
  • 91
    • 0030203145 scopus 로고    scopus 로고
    • Sepsis-induced alterations in pyruvate dehydrogenase complex activity in rat skeletal muscle: Effects on plasma lactate
    • (1996) Shock , vol.6 , pp. 89
    • Vary, T.C.1
  • 95
    • 0030124761 scopus 로고    scopus 로고
    • Protective effects of nicotinamide against nitric oxide-mediated delayed vascular failure in endotoxic shock: Potential involvement of polyADP ribosyl synthetase
    • (1996) Shock , vol.5 , pp. 258
    • Zingarelli, B.1    Salzman, A.L.2    Szabo, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.