Low-dose N-acetylcysteine protects rats against endotoxin-mediated oxidative stress, but high-dose increases mortality

American Journal of Respiratory and Critical Care Medicine

Volumn 157, Issue 4 PART I, 1998, Pages 1283-1293

  Sprong, R Corinne ^a   Winkelhuyzen Janssen, A Miranda L ^a   Aarsman, Colinda J M ^a   Van Oirschot, Johannes F L M ^a   Van Der Bruggen, Tjomme ^a   Van Asbeck, B Sweder ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; HYDROGEN PEROXIDE;

ANIMAL EXPERIMENT; ARTICLE; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; GLUTATHIONE METABOLISM; LUNG INJURY; MALE; MORTALITY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; CELL LINE; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; INFUSIONS, INTRAVENOUS; LIPOPOLYSACCHARIDES; LUNG; MALE; MONOCYTES; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, WISTAR; SERINE; SURVIVAL RATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031968245     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.157.4.9508063     Document Type: Article

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