A pharmacokinetic/pharmacodynamic approach vs. a dose titration for the determination of a dosage regimen: The case of nimesulide, a Cox-2 selective nonsteroidal anti-inflammatory drug in the dog

Journal of Veterinary Pharmacology and Therapeutics

Volumn 24, Issue 1, 2001, Pages 43-55

  Toutain, P L ^a   Cester, C C ^a   Haak, T ^a   Laroute, V ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; FREUND ADJUVANT; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; SULIDENE;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIPYRETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; ENZYME INHIBITION; HYPERTHERMIA; IC 50; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS; CROSS-OVER STUDIES; DOG DISEASES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEVER; FREUND'S ADJUVANT; LAMENESS, ANIMAL; SULFONAMIDES;

ANIMALIA; CANIS FAMILIARIS;

EID: 0035029513     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2885.2001.00304.x     Document Type: Article

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