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Volumn 170, Issue , 2008, Pages 589-601

Potential utility of aquaporin modulators for therapy of brain disorders

Author keywords

AQP4; brain oedema; cell migration; epilepsy; transgenic mouse; water transport

Indexed keywords

AQUAPORIN 4;

EID: 47749144297     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(08)00446-9     Document Type: Review
Times cited : (83)

References (65)
  • 4
    • 2442638032 scopus 로고    scopus 로고
    • Alpha-syntrophin deletion removes the perivascular but not endothelial pool of aquaporin-4 at the blood-brain barrier and delays the development of brain edema in an experimental model of acute hyponatremia
    • Amiry-Moghaddam M., Xue R., Haug F.M., Neely J.D., Bhardwaj A., Agre P., Adams M.E., Froehner S.C., Mori S., and Ottersen O.P. Alpha-syntrophin deletion removes the perivascular but not endothelial pool of aquaporin-4 at the blood-brain barrier and delays the development of brain edema in an experimental model of acute hyponatremia. Faseb J. 18 (2004) 542-544
    • (2004) Faseb J. , vol.18 , pp. 542-544
    • Amiry-Moghaddam, M.1    Xue, R.2    Haug, F.M.3    Neely, J.D.4    Bhardwaj, A.5    Agre, P.6    Adams, M.E.7    Froehner, S.C.8    Mori, S.9    Ottersen, O.P.10
  • 6
    • 33845974872 scopus 로고    scopus 로고
    • Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury
    • Auguste K.I., Jin S., Uchida K., Yan D., Manley G.T., Papadopoulos M.C., and Verkman A.S. Greatly impaired migration of implanted aquaporin-4-deficient astroglial cells in mouse brain toward a site of injury. Faseb J. 21 (2007) 108-116
    • (2007) Faseb J. , vol.21 , pp. 108-116
    • Auguste, K.I.1    Jin, S.2    Uchida, K.3    Yan, D.4    Manley, G.T.5    Papadopoulos, M.C.6    Verkman, A.S.7
  • 7
    • 34548119130 scopus 로고    scopus 로고
    • Temporal and regional evolution of aquaporin-4 expression and magnetic resonance imaging in a rat pup model of neonatal stroke
    • Badaut J., Ashwal S., Tone B., Regli L., Tian H.R., and Obenaus A. Temporal and regional evolution of aquaporin-4 expression and magnetic resonance imaging in a rat pup model of neonatal stroke. Pediatr. Res. 62 (2007) 248-254
    • (2007) Pediatr. Res. , vol.62 , pp. 248-254
    • Badaut, J.1    Ashwal, S.2    Tone, B.3    Regli, L.4    Tian, H.R.5    Obenaus, A.6
  • 9
    • 9344238209 scopus 로고    scopus 로고
    • Distribution and possible roles of aquaporin 9 in the brain
    • Badaut J., and Regli L. Distribution and possible roles of aquaporin 9 in the brain. Neuroscience 129 (2004) 971-981
    • (2004) Neuroscience , vol.129 , pp. 971-981
    • Badaut, J.1    Regli, L.2
  • 10
    • 1542290152 scopus 로고    scopus 로고
    • Increased seizure threshold in mice lacking aquaporin-4 water channels
    • Binder D.K., Oshio K., Ma T., Verkman A.S., and Manley G.T. Increased seizure threshold in mice lacking aquaporin-4 water channels. Neuroreport 15 (2004) 259-262
    • (2004) Neuroreport , vol.15 , pp. 259-262
    • Binder, D.K.1    Oshio, K.2    Ma, T.3    Verkman, A.S.4    Manley, G.T.5
  • 11
    • 4644268435 scopus 로고    scopus 로고
    • In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching
    • Binder D.K., Papadopoulos M.C., Haggie P.M., and Verkman A.S. In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching. J. Neurosci. 24 (2004) 8049-8056
    • (2004) J. Neurosci. , vol.24 , pp. 8049-8056
    • Binder, D.K.1    Papadopoulos, M.C.2    Haggie, P.M.3    Verkman, A.S.4
  • 12
    • 33646000806 scopus 로고    scopus 로고
    • Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels
    • Binder D.K., Yao X., Zador Z., Sick T.J., Verkman A.S., and Manley G.T. Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia 53 (2006) 631-636
    • (2006) Glia , vol.53 , pp. 631-636
    • Binder, D.K.1    Yao, X.2    Zador, Z.3    Sick, T.J.4    Verkman, A.S.5    Manley, G.T.6
  • 13
    • 33745066806 scopus 로고    scopus 로고
    • Accelerated progression of kaolin-induced hydrocephalus in aquaporin-4-deficient mice
    • Bloch O., Auguste K.I., Manley G.T., and Verkman A.S. Accelerated progression of kaolin-induced hydrocephalus in aquaporin-4-deficient mice. J. Cereb. Blood Flow Metab. 26 (2006) 1527-1537
    • (2006) J. Cereb. Blood Flow Metab. , vol.26 , pp. 1527-1537
    • Bloch, O.1    Auguste, K.I.2    Manley, G.T.3    Verkman, A.S.4
  • 14
    • 24344500555 scopus 로고    scopus 로고
    • Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess
    • Bloch O., Papadopoulos M.C., Manley G.T., and Verkman A.S. Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess. J. Neurochem. 95 (2005) 254-262
    • (2005) J. Neurochem. , vol.95 , pp. 254-262
    • Bloch, O.1    Papadopoulos, M.C.2    Manley, G.T.3    Verkman, A.S.4
  • 15
    • 0034014858 scopus 로고    scopus 로고
    • Inhibition of aquaporin-1 water permeability by tetraethylammonium: involvement of the loop E pore region
    • Brooks H.L., Regan J.W., and Yool A.J. Inhibition of aquaporin-1 water permeability by tetraethylammonium: involvement of the loop E pore region. Mol. Pharmacol. 57 (2000) 1021-1026
    • (2000) Mol. Pharmacol. , vol.57 , pp. 1021-1026
    • Brooks, H.L.1    Regan, J.W.2    Yool, A.J.3
  • 16
    • 36949031918 scopus 로고    scopus 로고
    • Effect of osmotherapy with hypertonic saline on regional cerebral edema following experimental stroke: a study utilizing magnetic resonance imaging
    • Chen C.H., Xue R., Zhang J., Li X., Mori S., and Bhardwaj A. Effect of osmotherapy with hypertonic saline on regional cerebral edema following experimental stroke: a study utilizing magnetic resonance imaging. Neurocrit. Care 7 (2007) 92-100
    • (2007) Neurocrit. Care , vol.7 , pp. 92-100
    • Chen, C.H.1    Xue, R.2    Zhang, J.3    Li, X.4    Mori, S.5    Bhardwaj, A.6
  • 17
    • 18844451469 scopus 로고    scopus 로고
    • Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture
    • Dolman D., Drndarski S., Abbott N.J., and Rattray M. Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture. J. Neurochem. 93 (2005) 825-833
    • (2005) J. Neurochem. , vol.93 , pp. 825-833
    • Dolman, D.1    Drndarski, S.2    Abbott, N.J.3    Rattray, M.4
  • 18
    • 0033180342 scopus 로고    scopus 로고
    • The glial scar and central nervous system repair
    • Fawcett J.W., and Asher R.A. The glial scar and central nervous system repair. Brain Res. Bull. 49 (1999) 377-391
    • (1999) Brain Res. Bull. , vol.49 , pp. 377-391
    • Fawcett, J.W.1    Asher, R.A.2
  • 20
    • 33645457522 scopus 로고    scopus 로고
    • Aquaporin-1 facilitates epithelial cell migration in kidney proximal tubule
    • Hara-Chikuma M., and Verkman A.S. Aquaporin-1 facilitates epithelial cell migration in kidney proximal tubule. J. Am. Soc. Nephrol. 17 (2006) 39-45
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 39-45
    • Hara-Chikuma, M.1    Verkman, A.S.2
  • 21
    • 33845591614 scopus 로고    scopus 로고
    • Increased migration and metastatic potential of tumor cells expressing aquaporin water channels
    • Hu J., and Verkman A.S. Increased migration and metastatic potential of tumor cells expressing aquaporin water channels. Faseb J. 20 (2006) 1892-1894
    • (2006) Faseb J. , vol.20 , pp. 1892-1894
    • Hu, J.1    Verkman, A.S.2
  • 23
    • 0023064395 scopus 로고
    • Comparative studies on the astrocytic reaction in the lesioned central nervous system of different vertebrates
    • Kastner R. Comparative studies on the astrocytic reaction in the lesioned central nervous system of different vertebrates. J. Hirnforsch 28 (1987) 221-232
    • (1987) J. Hirnforsch , vol.28 , pp. 221-232
    • Kastner, R.1
  • 24
    • 0036935126 scopus 로고    scopus 로고
    • Impact of experimental acute hyponatremia on severe traumatic brain injury in rats: influences on injuries, permeability of blood-brain barrier, ultrastructural features, and aquaporin-4 expression
    • Ke C., Poon W.S., Ng H.K., Lai F.M., Tang N.L., and Pang J.C. Impact of experimental acute hyponatremia on severe traumatic brain injury in rats: influences on injuries, permeability of blood-brain barrier, ultrastructural features, and aquaporin-4 expression. Exp. Neurol. 178 (2002) 194-206
    • (2002) Exp. Neurol. , vol.178 , pp. 194-206
    • Ke, C.1    Poon, W.S.2    Ng, H.K.3    Lai, F.M.4    Tang, N.L.5    Pang, J.C.6
  • 27
    • 33846846104 scopus 로고    scopus 로고
    • Urearetics: a small molecule screen yields nanomolar potency inhibitors of urea transporter UT-B
    • Levin M.H., de la Fuente R., and Verkman A.S. Urearetics: a small molecule screen yields nanomolar potency inhibitors of urea transporter UT-B. Faseb J. 21 (2007) 551-563
    • (2007) Faseb J. , vol.21 , pp. 551-563
    • Levin, M.H.1    de la Fuente, R.2    Verkman, A.S.3
  • 28
    • 33750584875 scopus 로고    scopus 로고
    • Aquaporin-3-dependent cell migration and proliferation during corneal re-epithelialization
    • Levin M.H., and Verkman A.S. Aquaporin-3-dependent cell migration and proliferation during corneal re-epithelialization. Invest. Ophthalmol. Vis. Sci. 47 (2006) 4365-4372
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 4365-4372
    • Levin, M.H.1    Verkman, A.S.2
  • 29
    • 0036156831 scopus 로고    scopus 로고
    • Mildly abnormal retinal function in transgenic mice without Muller cell aquaporin-4 water channels
    • Li J., Patil R.V., and Verkman A.S. Mildly abnormal retinal function in transgenic mice without Muller cell aquaporin-4 water channels. Invest. Ophthalmol. Vis. Sci. 43 (2002) 573-579
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 573-579
    • Li, J.1    Patil, R.V.2    Verkman, A.S.3
  • 30
    • 0035903098 scopus 로고    scopus 로고
    • Impaired hearing in mice lacking aquaporin-4 water channels
    • Li J., and Verkman A.S. Impaired hearing in mice lacking aquaporin-4 water channels. J. Biol. Chem. 276 (2001) 31233-31237
    • (2001) J. Biol. Chem. , vol.276 , pp. 31233-31237
    • Li, J.1    Verkman, A.S.2
  • 31
  • 33
    • 0347654959 scopus 로고    scopus 로고
    • Effects of acetazolamide and anordiol on osmotic water permeability in AQP1-cRNA injected Xenopus oocyte
    • Ma B., Xiang Y., Mu S.M., Li T., Yu H.M., and Li X.J. Effects of acetazolamide and anordiol on osmotic water permeability in AQP1-cRNA injected Xenopus oocyte. Acta Pharmacol. Sin. 25 (2004) 90-97
    • (2004) Acta Pharmacol. Sin. , vol.25 , pp. 90-97
    • Ma, B.1    Xiang, Y.2    Mu, S.M.3    Li, T.4    Yu, H.M.5    Li, X.J.6
  • 34
    • 0033966090 scopus 로고    scopus 로고
    • Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke
    • Manley G.T., Fujimura M., Ma T., Noshita N., Filiz F., Bollen A.W., Chan P., and Verkman A.S. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat. Med. 6 (2000) 159-163
    • (2000) Nat. Med. , vol.6 , pp. 159-163
    • Manley, G.T.1    Fujimura, M.2    Ma, T.3    Noshita, N.4    Filiz, F.5    Bollen, A.W.6    Chan, P.7    Verkman, A.S.8
  • 35
    • 2342507683 scopus 로고    scopus 로고
    • Correspondence of AQP4 expression and hypoxic-ischaemic brain oedema monitored by magnetic resonance imaging in the immature and juvenile rat
    • Meng S., Qiao M., Lin L., Del Bigio M.R., Tomanek B., and Tuor U.I. Correspondence of AQP4 expression and hypoxic-ischaemic brain oedema monitored by magnetic resonance imaging in the immature and juvenile rat. Eur. J. Neurosci. 19 (2004) 2261-2269
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 2261-2269
    • Meng, S.1    Qiao, M.2    Lin, L.3    Del Bigio, M.R.4    Tomanek, B.5    Tuor, U.I.6
  • 36
    • 0031022918 scopus 로고    scopus 로고
    • Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain
    • Nielsen S., Nagelhus E.A., Amiry-Moghaddam M., Bourque C., Agre P., and Ottersen O.P. Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J. Neurosci. 17 (1997) 171-180
    • (1997) J. Neurosci. , vol.17 , pp. 171-180
    • Nielsen, S.1    Nagelhus, E.A.2    Amiry-Moghaddam, M.3    Bourque, C.4    Agre, P.5    Ottersen, O.P.6
  • 37
    • 0027306170 scopus 로고
    • Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia
    • Nielsen S., Smith B.L., Christensen E.I., and Agre P. Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 7275-7279
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 7275-7279
    • Nielsen, S.1    Smith, B.L.2    Christensen, E.I.3    Agre, P.4
  • 38
    • 0037145839 scopus 로고    scopus 로고
    • New potent inhibitors of aquaporins: silver and gold compounds inhibit aquaporins of plant and human origin
    • Niemietz C.M., and Tyerman S.D. New potent inhibitors of aquaporins: silver and gold compounds inhibit aquaporins of plant and human origin. FEBS Lett. 531 (2002) 443-447
    • (2002) FEBS Lett. , vol.531 , pp. 443-447
    • Niemietz, C.M.1    Tyerman, S.D.2
  • 39
    • 11244254968 scopus 로고    scopus 로고
    • Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel aquaporin-1
    • Oshio K., Watanabe H., Song Y., Verkman A.S., and Manley G.T. Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel aquaporin-1. Faseb J. 19 (2005) 76-78
    • (2005) Faseb J. , vol.19 , pp. 76-78
    • Oshio, K.1    Watanabe, H.2    Song, Y.3    Verkman, A.S.4    Manley, G.T.5
  • 41
    • 4644314913 scopus 로고    scopus 로고
    • Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema
    • Papadopoulos M.C., Manley G.T., Krishna S., and Verkman A.S. Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. Faseb J. 18 (2004) 1291-1293
    • (2004) Faseb J. , vol.18 , pp. 1291-1293
    • Papadopoulos, M.C.1    Manley, G.T.2    Krishna, S.3    Verkman, A.S.4
  • 42
    • 43749084882 scopus 로고    scopus 로고
    • Papadopoulos, M.C., Saadoun, S. and Verkman, A.S. (2008) Aquaporins and cell migration. Pflugers Archiv, In press.
    • Papadopoulos, M.C., Saadoun, S. and Verkman, A.S. (2008) Aquaporins and cell migration. Pflugers Archiv, In press.
  • 43
    • 17144383572 scopus 로고    scopus 로고
    • Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis
    • Papadopoulos M.C., and Verkman A.S. Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis. J. Biol. Chem. 280 (2005) 13906-13912
    • (2005) J. Biol. Chem. , vol.280 , pp. 13906-13912
    • Papadopoulos, M.C.1    Verkman, A.S.2
  • 45
    • 9344233836 scopus 로고    scopus 로고
    • Freeze-fracture and immunogold analysis of aquaporin-4 (AQP4) square arrays, with models of AQP4 lattice assembly
    • Rash J.E., Davidson K.G., Yasumura T., and Furman C.S. Freeze-fracture and immunogold analysis of aquaporin-4 (AQP4) square arrays, with models of AQP4 lattice assembly. Neuroscience 129 (2004) 915-934
    • (2004) Neuroscience , vol.129 , pp. 915-934
    • Rash, J.E.1    Davidson, K.G.2    Yasumura, T.3    Furman, C.S.4
  • 46
    • 0032578454 scopus 로고    scopus 로고
    • Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord
    • Rash J.E., Yasumura T., Hudson C.S., Agre P., and Nielsen S. Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 11981-11986
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 11981-11986
    • Rash, J.E.1    Yasumura, T.2    Hudson, C.S.3    Agre, P.4    Nielsen, S.5
  • 47
    • 33646367654 scopus 로고    scopus 로고
    • Time course of aquaporin expression after transient focal cerebral ischemia in mice
    • Ribeiro Mde C., Hirt L., Bogousslavsky J., Regli L., and Badaut J. Time course of aquaporin expression after transient focal cerebral ischemia in mice. J. Neurosci. Res. 83 (2006) 1231-1240
    • (2006) J. Neurosci. Res. , vol.83 , pp. 1231-1240
    • Ribeiro Mde, C.1    Hirt, L.2    Bogousslavsky, J.3    Regli, L.4    Badaut, J.5
  • 49
    • 34547568729 scopus 로고    scopus 로고
    • Evidence against functional interaction between aquaporin-4 water channels and Kir4.1 potassium channels in retinal Muller cells
    • Ruiz-Ederra J., Zhang H., and Verkman A.S. Evidence against functional interaction between aquaporin-4 water channels and Kir4.1 potassium channels in retinal Muller cells. J. Biol. Chem. 282 (2007) 21866-21872
    • (2007) J. Biol. Chem. , vol.282 , pp. 21866-21872
    • Ruiz-Ederra, J.1    Zhang, H.2    Verkman, A.S.3
  • 51
    • 17144379334 scopus 로고    scopus 로고
    • Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption
    • Saadoun S., Papadopoulos M.C., Hara-Chikuma M., and Verkman A.S. Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature 434 (2005) 786-792
    • (2005) Nature , vol.434 , pp. 786-792
    • Saadoun, S.1    Papadopoulos, M.C.2    Hara-Chikuma, M.3    Verkman, A.S.4
  • 54
    • 0037372090 scopus 로고    scopus 로고
    • Regulation of aquaporin-4 in a traumatic brain injury model in rats
    • Sun M.C., Honey C.R., Berk C., Wong N.L., and Tsui J.K. Regulation of aquaporin-4 in a traumatic brain injury model in rats. J. Neurosurg. 98 (2003) 565-569
    • (2003) J. Neurosurg. , vol.98 , pp. 565-569
    • Sun, M.C.1    Honey, C.R.2    Berk, C.3    Wong, N.L.4    Tsui, J.K.5
  • 55
    • 0025245706 scopus 로고
    • Effects of dimethylsulfoxide and mercurial sulfhydryl reagents on water and solute permeability of rat kidney brush border membranes
    • van Hoek A.N., de Jong M.D., and van Os C.H. Effects of dimethylsulfoxide and mercurial sulfhydryl reagents on water and solute permeability of rat kidney brush border membranes. Biochim. Biophys. Acta 1030 (1990) 203-210
    • (1990) Biochim. Biophys. Acta , vol.1030 , pp. 203-210
    • van Hoek, A.N.1    de Jong, M.D.2    van Os, C.H.3
  • 56
    • 0030775672 scopus 로고    scopus 로고
    • Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4
    • Verbavatz J.M., Ma T., Gobin R., and Verkman A.S. Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4. J. Cell Sci. 110 (1997) 2855-2860
    • (1997) J. Cell Sci. , vol.110 , pp. 2855-2860
    • Verbavatz, J.M.1    Ma, T.2    Gobin, R.3    Verkman, A.S.4
  • 57
    • 0035214988 scopus 로고    scopus 로고
    • Potential utility of aquaporin blockers as aquaretics
    • Verkman A.S. Potential utility of aquaporin blockers as aquaretics. Drug News Perspect. 14 (2001) 412-420
    • (2001) Drug News Perspect. , vol.14 , pp. 412-420
    • Verkman, A.S.1
  • 59
    • 0032886241 scopus 로고    scopus 로고
    • Differential upregulation of aquaporin-4 mRNA expression in reactive astrocytes after brain injury: potential role in brain edema
    • Vizuete M.L., Venero J.L., Vargas C., Ilundain A.A., Echevarria M., Machado A., and Cano J. Differential upregulation of aquaporin-4 mRNA expression in reactive astrocytes after brain injury: potential role in brain edema. Neurobiol. Dis. 6 (1999) 245-258
    • (1999) Neurobiol. Dis. , vol.6 , pp. 245-258
    • Vizuete, M.L.1    Venero, J.L.2    Vargas, C.3    Ilundain, A.A.4    Echevarria, M.5    Machado, A.6    Cano, J.7
  • 61
    • 0029926097 scopus 로고    scopus 로고
    • The mercurial insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected Chinese hamster ovary cells
    • Yang B., Brown D., and Verkman A.S. The mercurial insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected Chinese hamster ovary cells. J. Biol. Chem. 271 (1996) 4577-4580
    • (1996) J. Biol. Chem. , vol.271 , pp. 4577-4580
    • Yang, B.1    Brown, D.2    Verkman, A.S.3
  • 63
    • 33745206921 scopus 로고    scopus 로고
    • Evidence against functionally significant aquaporin expression in mitochondria
    • Yang B., Zhao D., and Verkman A.S. Evidence against functionally significant aquaporin expression in mitochondria. J. Biol. Chem. 281 (2006) 16202-16206
    • (2006) J. Biol. Chem. , vol.281 , pp. 16202-16206
    • Yang, B.1    Zhao, D.2    Verkman, A.S.3
  • 64
    • 40449126722 scopus 로고    scopus 로고
    • Microfiberoptic fluorescence photobleaching reveals size-dependent macromolecule diffusion in extracellular space deep in brain
    • Zador Z., Magzoub S., Jin S., Manley G.T., Papadopoulos M.C., and Verkman A.S. Microfiberoptic fluorescence photobleaching reveals size-dependent macromolecule diffusion in extracellular space deep in brain. Faseb. J. 22 (2008) 870-879
    • (2008) Faseb. J. , vol.22 , pp. 870-879
    • Zador, Z.1    Magzoub, S.2    Jin, S.3    Manley, G.T.4    Papadopoulos, M.C.5    Verkman, A.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.