Kinetic analysis of Mad2-Cdc20 formation: Conformational changes in Mad2 are catalyzed by a C-Mad2-ligand complex

Biochemistry

Volumn 48, Issue 40, 2009, Pages 9503-9515

  Lad, Latesh ^a   Lichtsteiner, Serge ^a   Hartman, James J ^a   Wood, Kenneth W ^a   Sakowicz, Roman ^a,b  

^a Cytokinetics Inc   (United States)

^b GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVITY ASSAYS; BINDING INTERACTION; CHECKPOINT ACTIVATION; CONFORMATIONAL CHANGE; CORE COMPLEX; CURRENT MODELS; IN-VITRO; KINETIC ANALYSIS; LIGAND COMPLEXES; MITOTIC ARREST; SMALL-MOLECULE DRUGS; STRUCTURAL CHANGE; STRUCTURAL TRANSITIONS;

BINDING ENERGY; COMPLEXATION; LIGANDS;

CONFORMATIONS;

CELL CYCLE PROTEIN 20; LIGAND; PROTEIN MAD2;

ARTICLE; CATALYSIS; CENTROMERE; CONFORMATIONAL TRANSITION; KINETICS; MITOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DETERMINATION;

AMINO ACID SEQUENCE; CALCIUM-BINDING PROTEINS; CATALYSIS; CELL CYCLE PROTEINS; FLUORESCENCE POLARIZATION; HUMANS; KINETICS; LIGANDS; MITOTIC SPINDLE APPARATUS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; REPRESSOR PROTEINS;

EID: 70350070129     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900718e     Document Type: Article

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