CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment

Cell

Volumn 91, Issue 3, 1997, Pages 357-366

  Wood, Kenneth W ^a   Sakowicz, Roman ^a   Goldstein, Lawrence S B ^a   Cleveland, Don W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KINESIN; MICROTUBULE PROTEIN;

ANIMAL CELL; ARTICLE; CENTROMERE; CHROMOSOME; CONTROLLED STUDY; IMMUNOFLUORESCENCE MICROSCOPY; METAPHASE; METAPHASE CHROMOSOME; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOPUS;

ANIMALIA;

EID: 0030665077     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80419-5     Document Type: Article

References (50)

1. Bajer, A.S. (1982). Functional autonomy of monopolar spindle and evidence for oscillating movement in mitosis. J. Cell Biol. 93, 33-48.
2. Berger, B., Wilson, D.B., Wolf, E., Tonchev, T., Milla, M., and Kim, P.S. (1995). Predicting coiled coils by use of pairwise residue correlations. Proc. Natl. Acad. Sci. USA 92, 8259-8263.
3. Boulikas, T. (1993). Nuclear localization signals. Grit. Rev. Eukar. Gene Express. 3, 193-227.
4. Brown, K.D., Wood, K.W., and Cleveland, D.W. (1996). The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A. J. Cell Sci. 109, 961-969.
5. Case, R.B., Pierce, D.W., Hom-Booher, N., Hart, C., and Vale, R.D. (1997). The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain. Cell 90, 959-966.
6. Cassimeris, L., Rieder, C.L., and Salmon, E.D. (1994). Microtubule assembly and kinetochore directional instability in vertebrate monopolar spindles: implications for the mechanism of chromosome congression. J. Cell Sci. 107, 285-297.
7. Church, G.M., and Gilbert, W. (1984). Genomic sequencing. Proc. Natl. Acac. Sci. USA 81, 1991-1995.
8. Duesbery, N., Choi, T., Brown, K.D., Wood, K.W., Resau, J., Fukasawa, K., Cleveland, D.W., and Vande Woude, G.F. (1997). CENP-E is an essential kinetochore motor in maturing oocytes and is masked during Mos-dependent cell cycle arrest in metaphase II. Proc. Natl. Acad. Sci. USA 94, 9165-9170.
9. Evans, G.I., and Bishop, J.M. (1985). Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5, 3610-3616.
10. Heald, R., Tournebize, R., Blank, T., Sandaltzopoulos, R., Becker, P., Hyman, A., and Karsenti, E. (1996). Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature 382, 420-425.
11. Heald, R., Tournebize, R., Haberman, A., Karsenti, E., and Hyman, A. (1997). Spindle assembly in Xenopus egg extracts: respective roles of centrosomes and microtubule self-organization. J. Cell Biol. 138, 615-628.
12. Henningsen, U., and Schliwa, M. (1997). Reversal in the direction of movement of a molecular motor. Nature 389, 93-96.
13. Howard, J., and Hyman, A.A. (1993). Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence microscopy. In Motility Assays for Motor Proteins, J.M. Scholey, ed. (San Diego, CA: Academic Press, Inc.), pp. 105-113.
14. Hyman, A.A., and Karsenti, E. (1996). Morphogenetic properties of microtubules and mitotic spindle assembly. Cell 84, 401-410.
15. Hyman, A.A., and Mitchison, T.J. (1991). Two different microtubule-based motor activities with opposite polarities in kinetochores. Nature 351, 206-211.
16. Hyman, A.A., Drechsel, D., Kellogg, D., Salser, S., Sawin, K., Steffen, P., Wordeman, L., and Mitchison, T.J. (1992). Preparation of modified tubulins. In Methods in Enzymology, R.B. Vallee, ed. (San Diego, CA: Academic Press), pp. 478-485.
17. Inoue, S., and Salmon, E.D. (1996). Force generation by microtubule assembly/disassembly in mitosis and related movements. Mol. Biol. Cell 6, 1619-1640.
18. Khodjakov, A., and Rieder, C.L. (1996). Kinetochores moving away from their associated pole to not exert a significant pushing force on the chromosome. J. Cell Biol. 135, 315-327.
19. Kishino, A., and Yanagida, T. (1989). Force measurements by manipulation of a single actin filament. Nature 334, 74-76.
20. Kull, F.J., Sablin, E.P., Lau, R., Fletterick, R.J., and Vale, R.D. (1996). Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature 380, 550-555.
21. Lombillo, V.A., Nislow, C., Yen, T.J., Gelfand, V.I., and McIntosh, J.R. (1995a). Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro. J. Cell Biol. 128, 107-115.
22. Lombillo, V.A., Stewart, R.J., and McIntosh, R.J. (1995b). Kinesin supports minus end-directed, depolymerization-driven motility of microspheres coupled to shortening microtubules. Nature 373, 161-164.
23. Lupas, A., Van Dyke, M., and Stock, J. (1991). Predicting coiled coils from protein sequences. Science 252, 1162-1164.
24. Matthies, H.J.G., McDonald, H.B., Goldstein, L.S.B., and Theurkauf, W.E. (1996). Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein. J. Cell Biol. 134, 455-464.
25. McIntosh, J.R., and Euteneur, U. (1984). Tubulin hooks as probes for microtubule polarity: an analysis of the method and an evaluation of data on microtubule polarity in the mitotic spindle. J. Cell Biol. 98, 525-533.
26. Merdes, A., Ramyar, K., Vechio, J.D., and Cleveland, D.W. (1996). A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell 87, 447-458.
27. Mitchison, T.J. (1988). Microtubule dynamics and kinetochore function in mitosis. Annu. Rev. Cell Biol. 4, 527-549.
28. Mitchison, T.J., and Kirschner, M.W. (1985). Properties of the kinetochore in vitro. II. Microtubule capture and translocation. J. Cell Biol. 101, 766-777.
29. Mitchison, T.J., Evans, L., Schultz, E., and Kirschner, M.W. (1986). Sites of microtubule assembly and disassembly in the mitotic spindle. Cell 45, 515-527.
30. Moore, J.D., and Endow, S.A. (1996). Kinesin proteins: a phylum of motors for microtubule-based motility. Bioessays 18, 207-219. See also Kinesin Home Page http://www.blocks.fhcrc.org/̃kinesin/KinesinTree.html.
31. Murray, A.W. (1991). Cell cycle extracts. In Methods in Cell Biology, B.K. Kay and H.B. Peng, eds. (San Diego, CA: Academic Press), pp. 581-605.
32. Nicklas, R.B., and Kubai, D.F. (1985). Microtubules, chromosome movement, and reorientation after chromosomes are detached from the spindle by micromanipulation. Chromosoma 92, 313-324.
33. Nicklas, R.B., Ward, S.C., and Gorbsky, G.J. (1995). Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint. J. Cell Biol. 130, 929-939.
34. Rebagliati, M.R., Weeks, D.L., Harvey, R.P., and Melton, D.A. (1985). Identification and cloning of localized maternal mRNAs from Xenopus eggs. Cell 42, 769-777.
35. Rieder, C.L. (1982). The formation, structure, and composition of the mammalian kinetochore and kinetochore fiber. Int. Rev. Cytol. 79, 1-57.
36. Rieder, C.L., and Salmon, E.D. (1994). Motile kinetochores and polar ejection forces dictate chromosome position. J. Cell Biol. 124, 223-233.
37. Rieder, C.L., Davison, E.A., Jensen, L.C., Cassimeris, L., and Salmon, E.D. (1986). Oscillatory movements of monooriented chromosomes, and their position relative to the spindle pole, result from the ejection properties of the aster and half spindle. J. Cell Biol. 103, 581-591.
38. Roos, U.-P. (1976). Light and electron microscopy of rat kangaroo cells in mitosis. III. Patterns of chromosome behavior during prometaphase. Chromosoma 54, 363-385.
39. Sablin, E.P., Kull, F.J., Cooke, R., Vale, R.D., and Fletterick, R.J. (1996). Crystal structure of the motor domain of the kinesin-related motor ncd. Nature 380, 555-559.
40. Sawin, K.E., and Mitchison, T.J. (1991). Mitotic spindle assembly by two different pathways in vitro. J. Cell Biol. 112, 929-940.
41. Skibbens, R.V., Skeen, V.P., and Salmon, E.D. (1993). Directional instability of kinetochore motility during chomosome congression and segregation in mitotic newt lung cells: a push-pull mechanism. J. Cell Biol. 122, 859-876.
42. Skibbens, R.V., Rieder, C.L., and Salmon, E.D. (1995). Kinetochore motility after severing between sister centromeres using laser microsurgery: evidence that kinetochore directional instability and position is regulated by tension. J. Cell Sci. 108, 2537-2548.
43. Theurkauf, W.E., and Hawley, R.S. (1992). Meiotic spindle assembly in Drosophila females: behavior of non-exchange chromosome and the effects of mutations in the nod kinesin-like protein. J. Cell Biol. 116, 1167-1180.
44. Thrower, D.A., Jordan, M.A., Schaar, B.T., Yen, T.J., and Wilson, L. (1995). Mitotic HeLa cells contain a CENP-E-associated minus end-directed microtubule motor. EMBO J. 14, 918-926.
45. Walczak, C.E., Mitchison, T.J., and Desai, A. (1996). XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly. Cell 84, 37-47.
46. Waters, J.C., Skibbens, R.V., and Salmon, E.D. (1996). Oscillating mitotic newt lung kinetochores are, on average, under tension and rarely push. J. Cell Sci. 109, 2823-2831.
47. Wilson, P.G., Fuller, M.T., and Borisy, G.G. (1997). Monastral spindles: implications for dynamic centrosome organization. J. Cell Sci. 110, 451-464.
48. Yao, X., Anderson, K.L., and Cleveland, D.W. (1997). The microtubule motor CENP-E is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules. J. Cell Biol., in press.
49. Yen, T.J., Compton, D.A., Wise, D., Zinkowski, R., Brinkley, B.R., Earnshaw, W.C., and Cleveland, D.W. (1991). CENP-E, a novel centromere associated protein required for progression from metaphase to anaphase. EMBO J. 10, 1245-1254.
50. Yen, T.J., Li, G., Schaar, B.T., Szilak, I., and Cleveland, D.W. (1992). CENP-E is a putative kinetochore motor that accumulates just before mitosis. Nature 359, 536-539.