Serum deprivation induced autophagy and predominantly an AIF-dependent apoptosis in hippocampal HT22 neurons

Apoptosis

Volumn 14, Issue 11, 2009, Pages 1274-1288

  Steiger Barraissoul, S ^a   Rami, A ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

AIF; Autophagy; Beclin 1; Caspase 3; HT22 cells; LC3

Indexed keywords

3 METHYLADENINE; ALLOGRAFT INFLAMMATORY FACTOR 1; BAFILOMYCIN A1; BECLIN 1; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL PROTECTION; CONTROLLED STUDY; HIPPOCAMPUS; HUMAN; HUMAN CELL; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; PRIORITY JOURNAL; SERUM;

ADENINE; AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CASPASE 3; CELL LINE; CULTURE MEDIA, SERUM-FREE; HIPPOCAMPUS; MACROLIDES; MICE; MICROTUBULE-ASSOCIATED PROTEINS; NERVE DEGENERATION;

EID: 70349777675     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-009-0396-9     Document Type: Article

References (46)

1. M Villalba 1998 A possible role for PKC delta in cerebellar granule cells apoptosis NeuroReport 9 2381 2385 9694232 1:CAS:528:DyaK1cXltVKlt7c%3D (Pubitemid 28338238)
2. XH Liang LK Kleeman HH Jiang G Gordon JE Goldman G Berry B Herman B Levine 1998 Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein J Virol 72 8586 8596 9765397 1:CAS:528:DyaK1cXmslait7o%3D
3. T Yorimitsu DJ Klionsky 2005 Atg11 links cargo to the vesicle-forming machinery in the cytoplasm to vacuole targeting pathway Mol Biol Cell 16 1593 1605 15659643 10.1091/mbc.E04-11-1035 1:CAS:528:DC%2BD2MXjt1Kqtrs%3D (Pubitemid 40471933)
4. Z Yue A Horton M Bravin PL DeJager F Selimi N Heintz 2002 A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice Neuron 35 921 933 12372286 10.1016/S0896-6273(02)00861-9 1:CAS:528:DC%2BD38XntFSksrw%3D
5. AM Cuervo 2004 Autophagy: many paths to the same end Mol Cell Biochem 263 55 72 15524167 10.1023/B:MCBI.0000041848.57020.57 1:CAS:528: DC%2BD2cXotlCrtr4%3D (Pubitemid 39256145)
6. DJ Klionsky H Abeliovich P Agostinis DK Agrawal G Aliev DS Askew M Baba EH Baehrecke BA Bahr A Ballabio BA Bamber DC Bassham E Bergamini X Bi M Biard-Piechaczyk JS Blum DE Bredesen JL Brodsky JH Brumell UT Brunk W Bursch N Camougrand E Cebollero F Cecconi Y Chen LS Chin A Choi CT Chu J Chung PG Clarke RS Clark SG Clarke C Clave JL Cleveland P Codogno MI Colombo A Coto-Montes JM Cregg AM Cuervo J Debnath F Demarchi PB Dennis PA Dennis V Deretic RJ Devenish SF Di JF Dice M Difiglia S Dinesh-Kumar CW Distelhorst M Djavaheri-Mergny FC Dorsey W Droge M Dron WA Dunn Jr M Duszenko NT Eissa Z Elazar A Esclatine EL Eskelinen L Fesus KD Finley JM Fuentes J Fueyo K Fujisaki B Galliot FB Gao DA Gewirtz SB Gibson A Gohla AL Goldberg R Gonzalez C Gonzalez-Estevez S Gorski RA Gottlieb D Haussinger YW He K Heidenreich JA Hill M Hoyer-Hansen X Hu WP Huang A Iwasaki M Jaattela WT Jackson X Jiang S Jin T Johansen JU Jung M Kadowaki C Kang A Kelekar DH Kessel JA Kiel HP Kim A Kimchi TJ Kinsella K Kiselyov K Kitamoto E Knecht M Komatsu E Kominami S Kondo AL Kovacs G Kroemer CY Kuan R Kumar M Kundu J Landry M Laporte W Le HY Lei MJ Lenardo B Levine A Lieberman KL Lim FC Lin W Liou LF Liu G Lopez-Berestein C Lopez-Otin B Lu KF Macleod W Malorni W Martinet K Matsuoka J Mautner AJ Meijer A Melendez P Michels G Miotto WP Mistiaen N Mizushima B Mograbi I Monastyrska MN Moore PI Moreira Y Moriyasu T Motyl C Munz LO Murphy NI Naqvi TP Neufeld I Nishino RA Nixon T Noda B Nurnberg M Ogawa NL Oleinick LJ Olsen B Ozpolat S Paglin GE Palmer I Papassideri M Parkes DH Perlmutter G Perry M Piacentini R Pinkas-Kramarski M Prescott T Proikas-Cezanne N Raben A Rami F Reggiori B Rohrer DC Rubinsztein KM Ryan J Sadoshima H Sakagami Y Sakai M Sandri C Sasakawa M Sass C Schneider PO Seglen O Seleverstov J Settleman JJ Shacka IM Shapiro A Sibirny EC Silva-Zacarin HU Simon C Simone A Simonsen MA Smith K Spanel-Borowski V Srinivas M Steeves H Stenmark PE Stromhaug CS Subauste S Sugimoto D Sulzer T Suzuki MS Swanson I Tabas F Takeshita NJ Talbot Z Talloczy K Tanaka K Tanaka I Tanida GS Taylor JP Taylor A Terman G Tettamanti CB Thompson M Thumm AM Tolkovsky SA Tooze R Truant LV Tumanovska Y Uchiyama T Ueno NL Uzcategui I van der Klei EC Vaquero T Vellai MW Vogel HG Wang P Webster JW Wiley Z Xi G Xiao J Yahalom JM Yang G Yap XM Yin T Yoshimori L Yu Z Yue M Yuzaki O Zabirnyk X Zheng X Zhu RL Deter 2008 Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes Autophagy 4 151 175 18188003 1:CAS:528:DC%2BD1cXksFGrtLg%3D
7. KE Larsen D Sulzer 2002 Autophagy in neurons: a review Histol Histopathol 17 897 908 12168801 1:STN:280:DC%2BD38vhsVyjtA%3D%3D
8. C Gomez-Santos I Ferrer AF Santidrian M Barrachina J Gil S Ambrosio 2003 Dopamine induces autophagic cell death and alpha-synuclein increase in human neuroblastoma SH-SY5Y cells J Neurosci Res 73 341 350 12868068 10.1002/jnr.10663 1:CAS:528:DC%2BD3sXmt1Gjsrk%3D (Pubitemid 36918098)
9. L Xue GC Fletcher AM Tolkovsky 1999 Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death execution Mol Cell Neurosci 14 180 198 10576889 10.1006/mcne.1999.0780 1:CAS:528:DyaK1MXmtFOltLg%3D (Pubitemid 29449222)
10. KE Larsen EA Fon TG Hastings RH Edwards D Sulzer 2002 Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis J Neurosci 22 8951 8960 12388602 1:CAS:528:DC%2BD38XosV2isr4%3D
11. W Bursch 2001 The autophagosomal-lysosomal compartment in programmed cell death Cell Death Differ 8 569 581 11536007 10.1038/sj.cdd.4400852 1:CAS:528:DC%2BD3MXltFarurw%3D (Pubitemid 32590778)
12. N Canu R Tufi AL Serafino G Amadoro MT Ciotti P Calissano 2005 Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells J Neurochem 92 1228 1242 15715672 10.1111/j.1471-4159. 2004.02956.x 1:CAS:528:DC%2BD2MXitlehsr0%3D (Pubitemid 40344312)
13. A Rami A Langhagen S Steiger 2008 Focal cerebral ischemia induces upregulation of beclin 1 and autophagy-like cell death Neurobiol Dis 29 132 141 17936001 10.1016/j.nbd.2007.08.005 1:CAS:528:DC%2BD2sXhsVSns7fE (Pubitemid 350186114)
14. A Rami 2009 Autophagy in neurodegeneration: firefighter and/or incendiarist? Neuropath Appl Neurobiol 55 449 461 10.1111/j.1365-2990.2009. 01034.x
15. QJ Wang Y Ding DS Kohtz N Mizushima IM Cristea MP Rout BT Chait Y Zhong N Heintz Z Yue 2006 Induction of autophagy in axonal dystrophy and degeneration J Neurosci 26 8057 8068 16885219 10.1523/JNEUROSCI.2261-06.2006 1:CAS:528:DC%2BD28XosVeiu74%3D (Pubitemid 44315130)
16. B Boland V Campbell 2004 Abeta-mediated activation of the apoptotic cascade in cultured cortical neurones: a role for cathepsin-l Neurobiol Aging 25 83 91 14675734 10.1016/S0197-4580(03)00034-4 1:CAS:528:DC%2BD3sXpvVaitL8%3D (Pubitemid 37522196)
17. Y Uchiyama 2001 Autophagic cell death and its execution by lysosomal cathepsins Arch Histol Cytol 64 233 246 11575420 10.1679/aohc.64.233 1:STN:280:DC%2BD3MrivFGksA%3D%3D
18. M Koike H Nakanishi P Saftig J Ezaki K Isahara Y Ohsawa W Schulz-Schaeffer T Watanabe S Waguri S Kametaka M Shibata K Yamamoto E Kominami C Peters K von Figura Y Uchiyama 2000 Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons J Neurosci 20 6898 6906 10995834 1:CAS:528:DC%2BD3cXmvVGhsrc%3D
19. M Leist M Jaattela 2001 Four deaths and a funeral: from caspases to alternative mechanisms Nat Rev Mol Cell Biol 2 589 598 11483992 10.1038/35085008 1:CAS:528:DC%2BD3MXlvVOqs78%3D (Pubitemid 33674010)
20. M Leist M Jaattela 2001 Triggering of apoptosis by cathepsins Cell Death Differ 8 324 326 11550083 10.1038/sj.cdd.4400859 1:CAS:528:DC%2BD3MXktVOmsb0%3D (Pubitemid 32409602)
21. JM Adams 2003 Ways of dying: multiple pathways to apoptosis Genes Dev 17 2481 2495 14561771 10.1101/gad.1126903 1:CAS:528:DC%2BD3sXotlWjtL8%3D (Pubitemid 37271417)
22. D Green G Kroemer 1998 The central executioners of apoptosis: caspases or mitochondria? Trends Cell Biol 8 267 271 9714597 10.1016/S0962-8924(98)01273-2 1:CAS:528:DyaK1cXks1ylsrw%3D (Pubitemid 28310224)
23. DR Green JC Reed 1998 Mitochondria and apoptosis Science 281 1309 1312 9721092 10.1126/science.281.5381.1309 1:CAS:528:DyaK1cXlvVegsLo%3D
24. RM Friedlander 2003 Apoptosis and caspases in neurodegenerative diseases N Engl J Med 348 1365 1375 12672865 10.1056/NEJMra022366 1:CAS:528: DC%2BD3sXis1egtLw%3D (Pubitemid 36384105)
25. DJ Klionsky SD Emr 2000 Autophagy as a regulated pathway of cellular degradation Science 290 1717 1721 11099404 10.1126/science.290.5497.1717 1:CAS:528:DC%2BD3cXovVOitbw%3D (Pubitemid 32004796)
26. SA Susin HK Lorenzo N Zamzami I Marzo BE Snow GM Brothers J Mangion E Jacotot P Costantini M Loeffler N Larochette DR Goodlett R Aebersold DP Siderovski JM Penninger G Kroemer 1999 Molecular characterization of mitochondrial apoptosis-inducing factor Nature 397 441 446 9989411 10.1038/17135 1:CAS:528:DyaK1MXhtFOhu78%3D
27. E Daugas SA Susin N Zamzami KF Ferri T Irinopoulou N Larochette MC Prevost B Leber D Andrews J Penninger G Kroemer 2000 Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis FASEB J 14 729 739 10744629 1:CAS:528:DC%2BD3cXisFyhs7s%3D
28. C Cande F Cecconi P Dessen G Kroemer 2002 Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? J Cell Sci 115 4727 4734 12432061 10.1242/jcs.00210 1:CAS:528:DC%2BD3sXis1Kkuw%3D%3D (Pubitemid 36054627)
29. C Culmsee C Zhu S Landshamer B Becattini E Wagner M Pellecchia K Blomgren 2005 Plesnila N (2005) Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia J Neurosci 25 10262 10272 16267234 10.1523/JNEUROSCI.2818-05.2005 1:CAS:528:DC%2BD2MXht1Wqt7%2FP (Pubitemid 41636223)
30. C Zhu X Wang Z Huang L Qiu F Xu N Vahsen M Nilsson PS Eriksson H Hagberg C Culmsee N Plesnila G Kroemer K Blomgren 2007 Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia Cell Death Differ 14 775 784 17039248 10.1038/sj.cdd.4402053 1:CAS:528:DC%2BD2sXjt1Sku70%3D (Pubitemid 46444515)
31. N Plesnila C Zhu C Culmsee M Gröger MA Moskowitz K Blomgren 2004 Nucleartranslocation of apoptosis-inducing factor after focal cerebral ischemia J Cereb Blood Flow Metab 24 458 466 15087715 10.1097/00004647-200404000-00011 (Pubitemid 38452237)
32. A Rami I Bechmann JH Stehle 2008 Exploiting endogenous anti-apoptotic proteins for novel therapeutic strategies in cerebral ischemia Prog Neurobiol 85 273 296 18511172 10.1016/j.pneurobio.2008.04.003 1:CAS:528:DC%2BD1cXosVymurs%3D
33. A Rami D Kogel 2008 Apoptosis meets autophagy-like cell death in the ischemic penumbra: two sides of the same coin? Autophagy 4 422 426 18319639 1:CAS:528:DC%2BD1cXntFyntbw%3D
34. JC Reed G Kroemer 2000 Mechanisms of mitochondrial membrane permeabilization Cell Death Differ 7 1145 11175250 10.1038/sj.cdd.4400777 1:STN:280:DC%2BD3M3isVKmug%3D%3D (Pubitemid 32042220)
35. Y Kabeya N Mizushima T Ueno A Yamamoto T Kirisako T Noda E Kominami Y Ohsumi T Yoshimori 2000 LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing EMBO J 19 5720 5728 11060023 10.1093/emboj/19.21.5720 1:CAS:528:DC%2BD3cXovFaiurk%3D
36. N Mizushima A Yamamoto M Matsui T Yoshimori Y Ohsumi 2004 In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker Mol Biol Cell 15 1101 1111 14699058 10.1091/mbc.E03-09-0704 1:CAS:528:DC%2BD2cXitlGhu7g%3D (Pubitemid 38316219)
37. B Levine DJ Klionsky 2004 Development by self-digestion: molecular mechanisms and biological functions of autophagy Dev Cell 6 463 477 15068787 10.1016/S1534-5807(04)00099-1 1:CAS:528:DC%2BD2cXjsFeqsbs%3D (Pubitemid 38456176)
38. X Qu J Yu G Bhagat N Furuya H Hibshoosh A Troxel J Rosen EL Eskelinen N Mizushima Y Ohsumi G Cattoretti B Levine 2003 Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene J Clin Invest 112 1809 1820 14638851 1:CAS:528:DC%2BD3sXhtVSmtLvP
39. A Kihara Y Kabeya Y Ohsumi T Yoshimori 2001 Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network EMBO Rep 2 330 335 11306555 10.1093/embo-reports/kve061 1:CAS:528:DC%2BD3MXks1Cqtbc%3D (Pubitemid 32401529)
40. Z Yue S Jin C Yang AJ Levine N Heintz 2003 Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor Proc Natl Acad Sci USA 100 15077 15082 14657337 10.1073/pnas. 2436255100 1:CAS:528:DC%2BD3sXpvFaqtbg%3D (Pubitemid 37518019)
41. M Komatsu S Waguri T Chiba S Murata J Iwata I Tanida T Ueno M Koike Y Uchiyama E Kominami K Tanaka 2006 Loss of autophagy in the central nervous system causes neurodegeneration in mice Nature 441 880 884 16625205 10.1038/nature04723 1:CAS:528:DC%2BD28XlvVGlsbY%3D (Pubitemid 43910422)
42. T Hara K Nakamura M Matsui A Yamamoto Y Nakahara R Suzuki-Migishima M Yokoyama K Mishima I Saito H Okano N Mizushima 2006 Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice Nature 441 885 889 16625204 10.1038/nature04724 1:CAS:528:DC%2BD28XlvVGlsbc%3D (Pubitemid 43910423)
43. A Rami 2008 Upregulation of beclin 1 in the ischemic penumbra Autophagy 4 227 229 18075295 1:CAS:528:DC%2BD1cXksFGrurg%3D
44. HT Orr 2002 Lurcher, nPIST, and autophagy Neuron 35 813 814 12372273 10.1016/S0896-6273(02)00871-1 1:CAS:528:DC%2BD38XntFSjtL4%3D
45. J Hitomi DE Christofferson A Ng J Yao A Degterev RJ Xavier J Yuan 2008 Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway Cell 135 1311 1323 19109899 10.1016/j.cell.2008.10. 044 1:CAS:528:DC%2BD1MXisFyitg%3D%3D
46. A Kuma M Hatano M Matsui A Yamamoto H Nakaya T Yoshimori Y Ohsumi T Tokuhisa N Mizushima 2004 The role of autophagy during the early neonatal starvation period Nature 432 1032 1036 15525940 10.1038/nature03029 1:CAS:528:DC%2BD2cXhtFeisrnJ (Pubitemid 40052234)