The effect of formulation variables on the characteristics of insulin-loaded poly(lactic-co-glycolic acid) microspheres prepared by a single phase oil in oil solvent evaporation method

Colloids and Surfaces B: Biointerfaces

Volumn 74, Issue 1, 2009, Pages 340-349

  Hamishehkar, Hamed ^a   Emami, Jaber ^b   Najafabadi, Abdolhossein Rouholamini ^c   Gilani, Kambiz ^c   Minaiyan, Mohsen ^b   Mahdavi, Hamid ^d   Nokhodchi, Ali ^e  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d IRAN POLYMER AND PETROCHEMICAL INSTITUTE   (Iran)

^e MEDWAY SCHOOL OF PHARMACY   (United Kingdom)

Author keywords

Biodegradable microspheres; Insulin; Microencapsulation; PLGA; Protein delivery; Solvent evaporation

Indexed keywords

BIODEGRADABLE MICROSPHERES; MICROENCAPSULATION; PLGA; PROTEIN DELIVERY; SOLVENT EVAPORATION;

ACIDS; AMINES; CONCENTRATION (PROCESS); DRUG DELIVERY; DRUG INTERACTIONS; EMULSIFICATION; ENCAPSULATION; EVAPORATION; FOURIER TRANSFORM INFRARED SPECTROSCOPY; INSULIN; MICROSPHERES; MOLECULAR WEIGHT; PROTEINS; SCANNING ELECTRON MICROSCOPY; SOLVENTS; SURFACE ACTIVE AGENTS; SURFACE STRUCTURE; VAPORS;

BIODEGRADABLE POLYMERS;

MICROSPHERE; OIL; POLYGLACTIN; POLYMER; RECOMBINANT HUMAN INSULIN; SURFACTANT;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG FORMULATION; DRUG IDENTIFICATION; DRUG RELEASE; DRUG SCREENING; DRUG SYNTHESIS; EVAPORATION; EXPERIMENTAL DESIGN; FACTORIAL DESIGN; INFRARED SPECTROSCOPY; MICROEMULSION; MICROENCAPSULATION; MOLECULAR WEIGHT; PARTICLE SIZE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SCANNING ELECTRON MICROSCOPY; SOLVENT EXTRACTION; STRUCTURE ANALYSIS; SURFACE PROPERTY;

CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, GEL; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; HUMANS; INSULIN; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR WEIGHT; OILS; PARTICLE SIZE; POLYGLYCOLIC ACID; SOLVENTS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; VOLATILIZATION; X-RAY DIFFRACTION;

EID: 70349279873     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2009.08.003     Document Type: Article

References (54)

1. Vila A., Sanchez A., Tobio M., Calvo P., and Alonso M.J. J. Control. Release 78 (2002) 15
2. Cohen S., Chen L., and Apte R.N. React. Polym. 25 (1995) 177
3. Dai C., Wang B., and Zhao H. Colloid Surf. B 41 (2005) 117
4. Kim B., and Peppas N.A. Int. J. Pharm. 266 (2003) 29
5. Yushu H., and Venkatraman S. J. Appl. Polym. Sci. 101 (2006) 3053
6. Narayani R., and Rao K.P. Int. J. Pharm. 143 (1996) 255
7. Le Ray A.M., Chiffoleau S., Iooss P., Grimandi G., Gouyette A., Daculsi G., and Merle C. Biomaterials 24 (2003) 443
8. Jain R.A., Rhodes C.T., Railkar A.M., Malick A.W., and Shah N.H. Eur. J. Pharm. Biopharm. 50 (2000) 257
9. Herrman J., and Bodmeier R. Int. J. Pharm. 126 (1995) 129
10. Langer R. Acc. Chem. Res. 33 (2000) 94
11. Zhu G., Mallery S.R., and Schwendeman S.P. Nat. Biotechnol. 18 (2000) 52
12. Ruiz J.M., Tissier B., and Benoit J.P. Int. J. Pharm. 49 (1989) 69
13. Bodmeier R., and Chen H. Pharm. Pharmacol. 40 (1988) 754
14. Herrmann J., and Bodmeier R. Eur. J. Pharm. Biopharm. 45 (1998) 75
15. Emami J., Hamishehkar H., Rouholamini Najafabadi A., Gilani K., Minaiyan M., Mahdavi H., and Nokhodchi A. J. Pharm. Sci. 98 (2009) 1712
16. Agnihotri S.A., and Aminabhavi T.M. Int. J. Pharm. 324 (2006) 103
17. Emami J., Hamishehkar H., Rouholamini Najafabadi A., Gilani K., Minaiyan M., Mahdavi H., Mirzadeh H., Fakhari A., and Nokhodchi A. J. Microencapsul. 26 (2009) 1
18. Fiegel J., Fu J., and Hanes J. J. Control. Release 96 (2004) 411
19. Boury F., Marchais H., Proust J.E., and Benoit J.P. J. Control. Release 45 (1997) 75
20. Makino K., Nakajima T., Shikamura M., Ito F., Ando S., Kochi C., Inagawa H., Soma G.I., and Terada H. Colloid Surf. B 36 (2004) 35
21. Blanco D., and Alonso M.J. Eur. J. Pharm. Biopharm. 45 (1998) 285
22. Gaspar M.M., Blanco D., Cruz M.E.M., and Alonso M.J. J. Control. Release 52 (1998) 53
23. Yang Y.Y., Chung T.S., and Ng N.P. Biomaterials 22 (2001) 231
24. Freitas S., Merkle H.P., and Gander B. J. Control. Release 102 (2005) 313
25. Yang Y.Y., Chia H.H., and Chung T.S. J. Control. Release 69 (2000) 81
26. Mehta R.C., Thanoo B.C., and DeLuca P.P. J. Control. Release 41 (1996) 249
27. Crotts G., Sah H., and Park T.G. J. Control. Release 47 (1997) 101
28. Bittner B., Morlock M., Koll H., Winter G., and Kissel T. Eur. J. Pharm. Biopharm. 45 (1998) 295
29. Carrascosa C., Espejo L., Torrado S., and Torrado J.J. J. Biomater. Appl. 18 (2003) 95
30. Rojas J., Pinto-Alphandary H., Leo E., Pecquet S., Couvreur P., and Fattal E. Int. J. Pharm. 183 (1999) 67
31. Jiang G., Woo B.H., Kang F., Singh J., and DeLuca P.P. J. Control. Release 79 (2002) 137
32. Alonso M.J., Gupta R.K., Min C., Siber G.R., and Langer R. Vaccine 12 (1994) 299
33. Varde N.K., and Pack D.W. Expert Opin. Biol. Ther. 4 (2004) 35
34. Cui F., Shi K., Zhang L., Tao A., and Kawashima Y. J. Control. Release 114 (2006) 242
35. Leach W.T., Simpson D.T., Val T.N., Yu Z., Lim K.T., Park E.J., Williams R.O., and Johnston K.P. AAPS Pharm. Sci. Technol. 6 (2005) E605
36. Vandervoort J., and Ludwig A. Int. J. Pharm. 238 (2002) 77
37. Ma G.H., Nagai M., and Omi S. Colloid Surf. A 153 (1999) 383
38. Freiberg S., and Zhu X.X. Int. J. Pharm. 282 (2004) 1
39. Namur J.A., Cabral-Albuquerque E.C., Quintilio W., Santana M.H., Politi M.J., de Araujo P.S., Lopes A.C., and da Costa M.H. J. Nanosci. Nanotechnol. 6 (2006) 2403
40. Sansdrap P., and Moës A.J. Int. J. Pharm. 98 (1993) 157
41. Gabor F., Ertl B., Wirth M., and Mallinger R. J. Microencapsul. 16 (1999) 1
42. Marchais H., Boury F., Damgé C., Proust J.E., and Benoit J.P. S.T.P. Pharm. Sci. 6 (1996) 417
43. Jeyanthi R., Mehta R.C., Thanoo B.C., and DeLuca P.P. J. Microencapsul. 14 (1997) 163
44. Viswanathan N.B., Thomas P.A., Pandit J.K., Kulkarni M.G., and Mashelkar R.A. J. Control. Release 58 (1999) 9
45. Gélinas S., Chapados C., Beauregard M., Gosselin I., and Martinoli M.G. Biochem. Cell Biol. 78 (2000) 667
46. Park T.G., Lee H.Y., and Nam Y.S. J. Control. Release 55 (1998) 181
47. Coppi G., Iannuccelli V., Leo E., Bernabei M.T., and Cameroni R. J. Microencapsul. 19 (2002) 37
48. Huus K., Havelund S., Olsen H.B., van de Weert M., and Frokjaer S. Pharm. Res. 23 (2006) 2611
49. Sarmento B., Ferreira D., Veiga F., and Ribeiro A. Carbohydr. Polym. 66 (2006) 1
50. Lai M.C., and Topp E.M. J. Pharm. Sci. 88 (1999) 489
51. Wang W. Int. J. Pharm. 185 (1999) 129
52. Yamaguchi Y., Takenaga M., Kitagawa A., Ogawa Y., Mizushima Y., and Igarashi R. J. Control. Release 81 (2002) 235
53. Zhou S., Deng X., and Li X. J. Control. Release 75 (2001) 27
54. Aso Y., Yoshioka S., Wan Po A.L., and Terao T. J. Control. Release 31 (1994) 33