Effect of γ-sterilization process on PLGA microspheres loaded with insulin-like growth factor - I (IGF-I)

Journal of Biomaterials Applications

Volumn 18, Issue 2, 2003, Pages 95-108

  Carrascosa, C ^a   Espejo, L ^a   Torrado, S ^a   Torrado, J J ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Gamma irradiation; Microspheres; Poly(D, L lactide co glycolide); Recombinant human insulin like growth factor I

Indexed keywords

DIFFERENTIAL SCANNING CALORIMETRY; DOSIMETRY; ELECTROPHORESIS; EVAPORATION; INSULIN; IRRADIATION; PROTEINS; SCANNING ELECTRON MICROSCOPY; STERILIZATION (CLEANING);

CIRCULAR DICHROISM; GAMMA IRRADIATION; MICROSPHERES; PHYSICOCHEMICAL PROPERTIES; POLYLACTIDE-CO-GLYCOLIDE; RECOMBINANT HUMAN INSULIN LIKE GROWTH FACTOR; SODIUM DODECYL SULFATE POLYACRYLAMIDE GEL ELECTROPHORESIS; WATER-IN-OIL-IN-WATER SOLVENT EVAPORATION TECHNIQUE;

CONTROLLED DRUG DELIVERY;

LACTIC ACID; LIPOSOME; MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER; SOMATOMEDIN C;

ARTICLE; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG STABILITY; GAMMA RADIATION; INSTRUMENT STERILIZATION; METHODOLOGY; RADIATION EXPOSURE;

DELAYED-ACTION PREPARATIONS; DRUG STABILITY; GAMMA RAYS; INSULIN-LIKE GROWTH FACTOR I; LACTIC ACID; LIPOSOMES; MICROSPHERES; POLYGLYCOLIC ACID; POLYMERS; STERILIZATION;

EID: 0242365719     PISSN: 08853282     EISSN: None     Source Type: Journal    
DOI: 10.1177/088532803038026     Document Type: Article

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