-
1
-
-
0030835321
-
Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A
-
Aiken, C. 1997. Pseudotyping human immunodeficiency virus type 1 (HIV-1) by the glycoprotein of vesicular stomatitis virus targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A. J. Virol. 71:5871-5877.
-
(1997)
J. Virol.
, vol.71
, pp. 5871-5877
-
-
Aiken, C.1
-
2
-
-
0029015330
-
Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis
-
Aiken, C., and D. Trono. 1995. Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis. J. Virol. 69:5048-5056.
-
(1995)
J. Virol.
, vol.69
, pp. 5048-5056
-
-
Aiken, C.1
Trono, D.2
-
3
-
-
0031872106
-
Regions of human immunodeficiency virus type 1 nef required for function in vivo
-
Aldrovandi, G. M., L. Gao, G. Bristol, and J. A. Zack. 1998. Regions of human immunodeficiency virus type 1 nef required for function in vivo. J. Virol. 72:7032-7039.
-
(1998)
J. Virol.
, vol.72
, pp. 7032-7039
-
-
Aldrovandi, G.M.1
Gao, L.2
Bristol, G.3
Zack, J.A.4
-
4
-
-
0029670763
-
Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice
-
Aldrovandi, G. M., and J. A. Zack. 1996. Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice. J. Virol. 70:1505-1511.
-
(1996)
J. Virol.
, vol.70
, pp. 1505-1511
-
-
Aldrovandi, G.M.1
Zack, J.A.2
-
5
-
-
0028944667
-
Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques
-
Baba, T. W., Y. S. Jeong, D. Penninck, R. Bronson, M. F. Greene, and R. M. Ruprecht. 1995. Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science 267:1820-1825.
-
(1995)
Science
, vol.267
, pp. 1820-1825
-
-
Baba, T.W.1
Jeong, Y.S.2
Penninck, D.3
Bronson, R.4
Greene, M.F.5
Ruprecht, R.M.6
-
6
-
-
0032905068
-
Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques
-
Baba, T. W., V. Liska, A. H. Khimani, N. B. Ray, P. J. Dailey, D. Penninck, R. Bronson, M. F. Greene, H. M. McClure, L. N. Martin, and R. M. Ruprecht. 1999. Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques. Nat. Med. 5:194-203.
-
(1999)
Nat. Med.
, vol.5
, pp. 194-203
-
-
Baba, T.W.1
Liska, V.2
Khimani, A.H.3
Ray, N.B.4
Dailey, P.J.5
Penninck, D.6
Bronson, R.7
Greene, M.F.8
McClure, H.M.9
Martin, L.N.10
Ruprecht, R.M.11
-
7
-
-
0027158904
-
Downregulation of cell surface CD4 expression by SIV Nef prevents viral superinfection
-
Benson, R. E., A. Sanfridson, J. S. Ottinger, C. Doyle, and B. R. Cullen. 1993. Downregulation of cell surface CD4 expression by SIV Nef prevents viral superinfection. J. Exp. Med. 177:1561-1566.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1561-1566
-
-
Benson, R.E.1
Sanfridson, A.2
Ottinger, J.S.3
Doyle, C.4
Cullen, B.R.5
-
8
-
-
0024437414
-
A function for the Ick proto-oncogene
-
Bolen, J. B., and A. Veillette. 1989. A function for the Ick proto-oncogene. Trends Biochem. Sci. 14:404-407.
-
(1989)
Trends Biochem. Sci.
, vol.14
, pp. 404-407
-
-
Bolen, J.B.1
Veillette, A.2
-
9
-
-
0032488027
-
A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
-
Bresnahan, P. A., W. Yonemoto, S. Ferrell, D. Williams-Herman, R. Geleziunas, and W. C. Greene. 1998. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Curr. Biol. 8:1235-1238.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1235-1238
-
-
Bresnahan, P.A.1
Yonemoto, W.2
Ferrell, S.3
Williams-Herman, D.4
Geleziunas, R.5
Greene, W.C.6
-
10
-
-
0032750417
-
Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex
-
Brown, A., X. Wang, E. Sawai, and C. Cheng-Mayer. 1999. Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex. J. Virol. 73:9899-9907.
-
(1999)
J. Virol.
, vol.73
, pp. 9899-9907
-
-
Brown, A.1
Wang, X.2
Sawai, E.3
Cheng-Mayer, C.4
-
11
-
-
0028820530
-
The growth advantage conferred by HIV-1 Nef is determined at the level of viral DNA formation and is independent of CD4 downregulation
-
Chowers, M. Y., M. W. Pandori, C. A. Spina, D. D. Richman, and J. C. Guatelli. 1995. The growth advantage conferred by HIV-1 Nef is determined at the level of viral DNA formation and is independent of CD4 downregulation. Virology 212:451-457.
-
(1995)
Virology.
, vol.212
, pp. 451-457
-
-
Chowers, M.Y.1
Pandori, M.W.2
Spina, C.A.3
Richman, D.D.4
Guatelli, J.C.5
-
12
-
-
0028302998
-
Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene
-
Chowers, M. Y., C. A. Spina, T. J. Kwoh, N. J. S. Fitch, D. D. Richman, and J. C. Guatelli. 1994. Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene. J. Virol. 68:2906-2914.
-
(1994)
J. Virol.
, vol.68
, pp. 2906-2914
-
-
Chowers, M.Y.1
Spina, C.A.2
Kwoh, T.J.3
Fitch, N.J.S.4
Richman, D.D.5
Guatelli, J.C.6
-
13
-
-
0032556872
-
HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
-
Collins, K. L., B. K. Chen, S. A. Kalams, B. D. Walker, and D. Baltimore. 1998. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature 391:397-401.
-
(1998)
Nature
, vol.391
, pp. 397-401
-
-
Collins, K.L.1
Chen, B.K.2
Kalams, S.A.3
Walker, B.D.4
Baltimore, D.5
-
14
-
-
0032577444
-
HIV-1 auxilliary proteins: Making connections in a dying cell
-
Cullen, B. R. 1998. HIV-1 auxilliary proteins: making connections in a dying cell. Cell 93:685-692.
-
(1998)
Cell
, vol.93
, pp. 685-692
-
-
Cullen, B.R.1
-
15
-
-
0028804160
-
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
-
Deacon, N. J., A. Tsykin, A. Solomon, K. Smith, M. Ludford-Menting, A. Ellett, D. J. Hooker, D. A. McPhee, A. L. Greenway, C. Chatfield, V. A. Lawson, S. Crowe, A. Maerz, S. Sonza, J. Learmont, J. S. Sullivan, A. Cunningham, D. Dwyer, D. Dowton, and J. Mills. 1995. Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients. Science 270:988-991.
-
(1995)
Science
, vol.270
, pp. 988-991
-
-
Deacon, N.J.1
Tsykin, A.2
Solomon, A.3
Smith, K.4
Ludford-Menting, M.5
Ellett, A.6
Hooker, D.J.7
McPhee, D.A.8
Greenway, A.L.9
Chatfield, C.10
Lawson, V.A.11
Crowe, S.12
Maerz, A.13
Sonza, S.14
Learmont, J.15
Sullivan, J.S.16
Cunningham, A.17
Dwyer, D.18
Dowton, D.19
Mills, J.20
more..
-
16
-
-
0035083650
-
Separation of human immunodeficiency virus type 1 replication from Nef-mediated pathogenesis in the human thymus
-
Duus, K. M., E. D. Miller, J. A. Smith, G. I. Kovalev, and L. Su. 2001. Separation of human immunodeficiency virus type 1 replication from Nef-mediated pathogenesis in the human thymus. J. Virol. 8:3916-3924.
-
(2001)
J. Virol.
, vol.8
, pp. 3916-3924
-
-
Duus, K.M.1
Miller, E.D.2
Smith, J.A.3
Kovalev, G.I.4
Su, L.5
-
17
-
-
0034064726
-
p21-activated kinase 1 plays a critical role in cellular activation by Nef
-
Fackler, O. T., X. Lu, J. A. Frost, M. Geyer, B. Jiang, W. Luo, A. Abo, A. S. Alberts, and B. M. Peterlin. 2000. p21-activated kinase 1 plays a critical role in cellular activation by Nef. Mol. Cell. Biol. 20:2619-2627.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2619-2627
-
-
Fackler, O.T.1
Lu, X.2
Frost, J.A.3
Geyer, M.4
Jiang, B.5
Luo, W.6
Abo, A.7
Alberts, A.S.8
Peterlin, B.M.9
-
18
-
-
0033153464
-
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
-
Fackler, O. T., W. Luo, M. Geyer, A. S. Alberts, and B. M. Peterlin. 1999. Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol. Cell 3:729-739.
-
(1999)
Mol. Cell
, vol.3
, pp. 729-739
-
-
Fackler, O.T.1
Luo, W.2
Geyer, M.3
Alberts, A.S.4
Peterlin, B.M.5
-
19
-
-
0025733252
-
Serine phosphorylation-independent downregulation of cell surface CD4 by Nef
-
Garcia, J. V., and A. D. Miller. 1991. Serine phosphorylation-independent downregulation of cell surface CD4 by Nef. Nature 350:508-511.
-
(1991)
Nature
, vol.350
, pp. 508-511
-
-
Garcia, J.V.1
Miller, A.D.2
-
21
-
-
0035848864
-
HIV-1 Nef inhibits ASK-1-dependent death signalling providing a potential mechanism for protecting the infected host cell
-
Geleziunas, R., W. Xu, K. Takeda, H. Ichijo, and W. C. Greene. 2001. HIV-1 Nef inhibits ASK-1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 410:834-838.
-
(2001)
Nature
, vol.410
, pp. 834-838
-
-
Geleziunas, R.1
Xu, W.2
Takeda, K.3
Ichijo, H.4
Greene, W.C.5
-
23
-
-
0033591684
-
Human herpesvirus 6 (HHV-6) causes severe thymocyte depletion in SCID-hu Thy/Liv mice
-
Gobbi, A., C. A. Stoddart, M. S. Malnati, G. Locatelli, F. Santoro, N. W. Abbey, C. Bare, V. Linquist-Stepps, M. B. Moreno, B. G. Herndier, P. Lusso, and J. M. McCune. 1999. Human herpesvirus 6 (HHV-6) causes severe thymocyte depletion in SCID-hu Thy/Liv mice. J. Exp. Med. 189:1953-1960.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1953-1960
-
-
Gobbi, A.1
Stoddart, C.A.2
Malnati, M.S.3
Locatelli, G.4
Santoro, F.5
Abbey, N.W.6
Bare, C.7
Linquist-Stepps, V.8
Moreno, M.B.9
Herndier, B.G.10
Lusso, P.11
McCune, J.M.12
-
24
-
-
0029046227
-
Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef
-
Goldsmith, M. A., M. T. Warmerdam, R. E. Atchison, M. D. Miller, and W. C. Greene. 1995. Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef. J. Virol. 69:4112-4121.
-
(1995)
J. Virol.
, vol.69
, pp. 4112-4121
-
-
Goldsmith, M.A.1
Warmerdam, M.T.2
Atchison, R.E.3
Miller, M.D.4
Greene, W.C.5
-
25
-
-
0032488055
-
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
-
Greenberg, M., L. DeTulleo, I. Rapoport, J. Skowronski, and T. Kirchhausen. 1998. A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. Curr. Biol. 8:1239-1242.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1239-1242
-
-
Greenberg, M.1
DeTulleo, L.2
Rapoport, I.3
Skowronski, J.4
Kirchhausen, T.5
-
26
-
-
0032525137
-
The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes
-
Greenberg, M. E., A. J. Iafrate, and J. Skowronski. 1998. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. EMBO J. 17:2777-2789.
-
(1998)
EMBO J.
, vol.17
, pp. 2777-2789
-
-
Greenberg, M.E.1
Iafrate, A.J.2
Skowronski, J.3
-
27
-
-
0033590405
-
Declining CD4 T-cell counts in a person infected with Nef-deleted HIV-1
-
Greenough, T. C., J. L. Sullivan, and R. C. Desrosiers. 1999. Declining CD4 T-cell counts in a person infected with Nef-deleted HIV-1. N. Engl. J. Med. 340:236-237.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 236-237
-
-
Greenough, T.C.1
Sullivan, J.L.2
Desrosiers, R.C.3
-
28
-
-
0029795040
-
The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef: Mapping of the Nef binding surface by NMR
-
Grzesiek, S., S. J. Stahl, P. T. Wingfield, and A. Bax. 1996. The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef: mapping of the Nef binding surface by NMR. Biochemistry 35:10256-10261.
-
(1996)
Biochemistry
, vol.35
, pp. 10256-10261
-
-
Grzesiek, S.1
Stahl, S.J.2
Wingfield, P.T.3
Bax, A.4
-
29
-
-
0032538278
-
Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
-
Hanna, Z., D. G. Kay, N. Rebai, A. Guimond, S. Jothy, and P. Jolicoeur. 1998. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 95:163-175.
-
(1998)
Cell
, vol.95
, pp. 163-175
-
-
Hanna, Z.1
Kay, D.G.2
Rebai, N.3
Guimond, A.4
Jothy, S.5
Jolicoeur, P.6
-
30
-
-
0033775488
-
Disrupting surfaces of Nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo
-
Iafrate, A. J., S. Carl, S. Bronson, C. Stahl-Hennig, T. Swigut, J. Skowronski, and F. Kirchhoff. 2000. Disrupting surfaces of Nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo. J. Virol. 74:9836-9844.
-
(2000)
J. Virol.
, vol.74
, pp. 9836-9844
-
-
Iafrate, A.J.1
Carl, S.2
Bronson, S.3
Stahl-Hennig, C.4
Swigut, T.5
Skowronski, J.6
Kirchhoff, F.7
-
31
-
-
0028246191
-
Requirement of human immunodeficiency virus type 1 Nef for in vivo replication and pathogenicity
-
Jamieson, B. D., G. M. Aldrovandi, V. Planelles, J. B. Jowett, L. Gao, L. M. Bloch, I. S. Chen, and J. A. Zack. 1994. Requirement of human immunodeficiency virus type 1 Nef for in vivo replication and pathogenicity. J. Virol. 68:3478-3485.
-
(1994)
J. Virol.
, vol.68
, pp. 3478-3485
-
-
Jamieson, B.D.1
Aldrovandi, G.M.2
Planelles, V.3
Jowett, J.B.4
Gao, L.5
Bloch, L.M.6
Chen, I.S.7
Zack, J.A.8
-
32
-
-
0002051756
-
Quantitative assays for virus infectivity
-
A. Aldovini and B. D. Walker (ed.). Stockton Press, London, United Kingdom
-
Johnson, V. A., and R. E. Byington. 1990. Quantitative assays for virus infectivity, p. 71. In A. Aldovini and B. D. Walker (ed.), Techniques in HIV research. Stockton Press, London, United Kingdom.
-
(1990)
Techniques in HIV Research
, pp. 71
-
-
Johnson, V.A.1
Byington, R.E.2
-
33
-
-
0025743306
-
Importance of the nef gene for maintenance of high virus loads and for development of AIDS
-
Kestler, H. W. d., D. J. Ringler, K. Mori, D. L. Panicali, P. K. Sehgal, M. D. Daniel, and R. C. Desrosiers. 1991. Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 65:651-662.
-
(1991)
Cell
, vol.65
, pp. 651-662
-
-
Kestler, H.W.D.1
Ringler, D.J.2
Mori, K.3
Panicali, D.L.4
Sehgal, P.K.5
Daniel, M.D.6
Desrosiers, R.C.7
-
34
-
-
0031777959
-
Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaques
-
Khan, 1. H., E. T. Sawai, E. Antonio, C. J. Weber, C. P. Mandell, P. Montbriand, and P. A. Luciw. 1998. Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaques. J. Virol. 72:5820-5830.
-
(1998)
J. Virol.
, vol.72
, pp. 5820-5830
-
-
Khan, I.H.1
Sawai, E.T.2
Antonio, E.3
Weber, C.J.4
Mandell, C.P.5
Montbriand, P.6
Luciw, P.A.7
-
35
-
-
0028835788
-
Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
-
Kirchhoff, F., T. C. Greenough, D. B. Brettler, J. L. Sullivan, and R. C. Desrosiers. 1995. Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N. Engl. J. Med. 332:228-232.
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 228-232
-
-
Kirchhoff, F.1
Greenough, T.C.2
Brettler, D.B.3
Sullivan, J.L.4
Desrosiers, R.C.5
-
36
-
-
0033578072
-
Cell surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner
-
Lama, J., A. Mangasarian, and D. Trono. 1999. Cell surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner. Curr. Biol. 9:622-631.
-
(1999)
Curr. Biol.
, vol.9
, pp. 622-631
-
-
Lama, J.1
Mangasarian, A.2
Trono, D.3
-
37
-
-
0030836543
-
Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques
-
Lang, S. M., A. J. Iafrate, H. C. Stahl, E. M. Kuhn, T. Nisslein, F. J. Kaup, M. Haupt, G. Hunsmann, J. Skowronski, and F. Kirchhoff. 1997. Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques. Nat. Med. 3:860-865.
-
(1997)
Nat. Med.
, vol.3
, pp. 860-865
-
-
Lang, S.M.1
Iafrate, A.J.2
Stahl, H.C.3
Kuhn, E.M.4
Nisslein, T.5
Kaup, F.J.6
Haupt, M.7
Hunsmann, G.8
Skowronski, J.9
Kirchhoff, F.10
-
38
-
-
0033519616
-
Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1: A report from the Sydney Blood Bank Cohort
-
Learmont, J. C., A. F. Geczy, J. Mills, L. J. Ashton, C. H. Raynes-Greenow, R. J. Garsia, W. B. Dyer, L. McIntyre, R. B. Oelrichs, D. I. Rhodes, N. J. Deacon, and J. S. Sullivan. 1999. Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1: a report from the Sydney Blood Bank Cohort. N. Engl. J. Med. 340:1715-1722.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1715-1722
-
-
Learmont, J.C.1
Geczy, A.F.2
Mills, J.3
Ashton, L.J.4
Raynes-Greenow, C.H.5
Garsia, R.J.6
Dyer, W.B.7
McIntyre, L.8
Oelrichs, R.B.9
Rhodes, D.I.10
Deacon, N.J.11
Sullivan, J.S.12
-
39
-
-
0032055774
-
Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules
-
Le Gall, S., L. Erdtmann, S. Benichou, C. Berlioz-Torrent, L. Liu, R. Benarous, J. M. Heard, and O. Schwartz. 1998. Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. Immunity 8:483-495.
-
(1998)
Immunity
, vol.8
, pp. 483-495
-
-
Le Gall, S.1
Erdtmann, L.2
Benichou, S.3
Berlioz-Torrent, C.4
Liu, L.5
Benarous, R.6
Heard, J.M.7
Schwartz, O.8
-
40
-
-
0027955426
-
Severe immunodeficiency associated with an HIV-1 Nef/3′ long terminal repeat transgene
-
Lindemann, D., R. Wilhelm, P. Renard, A. Althage, R. Zinkernagel, and J. Mous. 1994. Severe immunodeficiency associated with an HIV-1 Nef/3′ long terminal repeat transgene. J. Exp. Med. 179:797-807.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 797-807
-
-
Lindemann, D.1
Wilhelm, R.2
Renard, P.3
Althage, A.4
Zinkernagel, R.5
Mous, J.6
-
41
-
-
0033577730
-
Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis
-
Lock, M., M. E. Greenberg, A. J. Iafrate, T. Swigut, J. Muench, F. Kirchhoff, N. Shohdy, and J. Skowronski. 1999. Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis. EMBO J. 18:2722-2733.
-
(1999)
EMBO J.
, vol.18
, pp. 2722-2733
-
-
Lock, M.1
Greenberg, M.E.2
Iafrate, A.J.3
Swigut, T.4
Muench, J.5
Kirchhoff, F.6
Shohdy, N.7
Skowronski, J.8
-
42
-
-
0032076086
-
Interactions between HIV-1 Nef and vacuolar ATPase facilitate the internalization of CD4
-
Lu, X., H. Yu, S. H. Liu, F. M. Brodsky, and B. M. Peterlin. 1998. Interactions between HIV-1 Nef and vacuolar ATPase facilitate the internalization of CD4. Immunity 8:647-656.
-
(1998)
Immunity
, vol.8
, pp. 647-656
-
-
Lu, X.1
Yu, H.2
Liu, S.H.3
Brodsky, F.M.4
Peterlin, B.M.5
-
43
-
-
0036231461
-
Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes
-
Lundquist, C. A., M. Tobiume, J. Zhou, D. Unutmaz, and C. Aiken. 2002. Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes. J. Virol. 9:4625-4633.
-
(2002)
J. Virol.
, vol.9
, pp. 4625-4633
-
-
Lundquist, C.A.1
Tobiume, M.2
Zhou, J.3
Unutmaz, D.4
Aiken, C.5
-
44
-
-
0030614819
-
The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane
-
Mangasarian, A., M. Foti, C. Aiken, D. Chin, J. L. Carpentier, and D. Trono. 1997. The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane. Immunity 6:67-77.
-
(1997)
Immunity
, vol.6
, pp. 67-77
-
-
Mangasarian, A.1
Foti, M.2
Aiken, C.3
Chin, D.4
Carpentier, J.L.5
Trono, D.6
-
45
-
-
0033013962
-
Nef-induced CD4 and major histocompatibility complex class I (MHC class I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC class I trafficking
-
Mangasarian, A., V. Piguet, J. K. Wang, Y. L. Chen, and D. Trono. 1999. Nef-induced CD4 and major histocompatibility complex class I (MHC class I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC class I trafficking. J. Virol. 73:1964-1973.
-
(1999)
J. Virol.
, vol.73
, pp. 1964-1973
-
-
Mangasarian, A.1
Piguet, V.2
Wang, J.K.3
Chen, Y.L.4
Trono, D.5
-
46
-
-
0029846223
-
High frequency of defective nef alleles in a longterm survivor with nonprogressive human immunodeficiency virus type 1 infection
-
Mariani, R., F. Kirchhoff, T. C. Greenough, J. L. Sullivan, R. C. Desrosiers, and J. Skowronski. 1996. High frequency of defective nef alleles in a longterm survivor with nonprogressive human immunodeficiency virus type 1 infection. J. Virol. 70:7752-7764.
-
(1996)
J. Virol.
, vol.70
, pp. 7752-7764
-
-
Mariani, R.1
Kirchhoff, F.2
Greenough, T.C.3
Sullivan, J.L.4
Desrosiers, R.C.5
Skowronski, J.6
-
47
-
-
0033562115
-
The numerous effector functions of Nef
-
Marsh, J. W. 1999. The numerous effector functions of Nef. Arch. Biochem. Biophys. 365:192-198.
-
(1999)
Arch. Biochem. Biophys.
, vol.365
, pp. 192-198
-
-
Marsh, J.W.1
-
48
-
-
0028006247
-
The HIV-1 Nef gene product: A positive factor for viral infection and replication in primary lymphocytes and macrophages
-
Miller, M. D., M. T. Warmerdam, I. Gaston, W. C. Greene, and M. B. Feinberg. 1994. The HIV-1 Nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J. Exp. Med. 179:101-113.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 101-113
-
-
Miller, M.D.1
Warmerdam, M.T.2
Gaston, I.3
Greene, W.C.4
Feinberg, M.B.5
-
49
-
-
0028936207
-
Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry
-
Miller, M. D., M. T. Warmerdam, K. A. Page, M. B. Feinberg, and W. C. Greene. 1995. Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry. J. Virol. 69:570-584.
-
(1995)
J. Virol.
, vol.69
, pp. 570-584
-
-
Miller, M.D.1
Warmerdam, M.T.2
Page, K.A.3
Feinberg, M.B.4
Greene, W.C.5
-
50
-
-
0025052646
-
Long-term human hematopoiesis in the SCID-hu mouse
-
Namikawa, R., K. N. Weilbaecher, H. Kaneshima, E. J. Yee, and J. M. McCune. 1990. Long-term human hematopoiesis in the SCID-hu mouse. J. Exp. Med. 172:1055-1063.
-
(1990)
J. Exp. Med.
, vol.172
, pp. 1055-1063
-
-
Namikawa, R.1
Weilbaecher, K.N.2
Kaneshima, H.3
Yee, E.J.4
McCune, J.M.5
-
51
-
-
0029793714
-
Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family
-
Nunn, M. F., and J. W. Marsh. 1996. Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family. J. Virol. 70:6157-6161.
-
(1996)
J. Virol.
, vol.70
, pp. 6157-6161
-
-
Nunn, M.F.1
Marsh, J.W.2
-
52
-
-
0030014162
-
Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein
-
Pandori, M. W., N. J. S. Fitch, H. M. Craig, D. D. Richman, C. A. Spina, and J. C. Guatelli. 1996. Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein. J. Virol. 70:4283-4290.
-
(1996)
J. Virol.
, vol.70
, pp. 4283-4290
-
-
Pandori, M.W.1
Fitch, N.J.S.2
Craig, H.M.3
Richman, D.D.4
Spina, C.A.5
Guatelli, J.C.6
-
53
-
-
0032191169
-
HIV Nef: The mother of all evil?
-
Peter, F. 1998. HIV Nef: the mother of all evil? Immunity 9:433-437.
-
(1998)
Immunity
, vol.9
, pp. 433-437
-
-
Peter, F.1
-
54
-
-
0032079665
-
Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes
-
Piguet, V., Y. L. Chen, A. Mangasarian, M. Foti, J. L. Carpentier, and D. Trono. 1998. Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. EMBO J. 17:2472-2481.
-
(1998)
EMBO J.
, vol.17
, pp. 2472-2481
-
-
Piguet, V.1
Chen, Y.L.2
Mangasarian, A.3
Foti, M.4
Carpentier, J.L.5
Trono, D.6
-
55
-
-
0033776709
-
HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes
-
Piguet, V., L. Wan, C. Borel, A. Mangasarian, N. Demaurex, G. Thomas, and D. Trono. 2000. HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes. Nat. Cell Biol. 2:163-167.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 163-167
-
-
Piguet, V.1
Wan, L.2
Borel, C.3
Mangasarian, A.4
Demaurex, N.5
Thomas, G.6
Trono, D.7
-
56
-
-
9044240866
-
Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds
-
Rabin, L., M. Hincenbergs, M. B. Moreno, S. Warren, V. Linquist, R. Datema, B. Charpiot, J. Seifert, H. Kaneshima, and J. M. McCune. 1996. Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds. Antimicrob. Agents Chemother. 40:755-762.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 755-762
-
-
Rabin, L.1
Hincenbergs, M.2
Moreno, M.B.3
Warren, S.4
Linquist, V.5
Datema, R.6
Charpiot, B.7
Seifert, J.8
Kaneshima, H.9
McCune, J.M.10
-
57
-
-
0033518291
-
Identification of the Nef-associated kinase as p21-activated kinase 2
-
Renkema, G. H., A. Manninen, D. A. Mann, M. Harris, and K. Saksela. 1999. Identification of the Nef-associated kinase as p21-activated kinase 2. Curr. Biol. 9:1407-1410.
-
(1999)
Curr. Biol.
, vol.9
, pp. 1407-1410
-
-
Renkema, G.H.1
Manninen, A.2
Mann, D.A.3
Harris, M.4
Saksela, K.5
-
58
-
-
0033230961
-
Identification of a new recipient in the Sydney Blood Bank Cohort: A long-term HIV type 1-infected seroindeterminate individual
-
Rhodes, D., A. Solomon, W. Bolton, J. Wood, J. Sullivan, J. Learmont, and N. Deacon. 1999. Identification of a new recipient in the Sydney Blood Bank Cohort: a long-term HIV type 1-infected seroindeterminate individual. AIDS Res. Hum. Retrovir. 15:1433-1439.
-
(1999)
AIDS Res. Hum. Retrovir.
, vol.15
, pp. 1433-1439
-
-
Rhodes, D.1
Solomon, A.2
Bolton, W.3
Wood, J.4
Sullivan, J.5
Learmont, J.6
Deacon, N.7
-
59
-
-
0029014901
-
Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae
-
Robbins, S. M., N. A. Quintrell, and J. M. Bishop. 1995. Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae. Mol. Cell. Biol. 15:3507-3515.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3507-3515
-
-
Robbins, S.M.1
Quintrell, N.A.2
Bishop, J.M.3
-
60
-
-
0033578016
-
Inhibition of HIV-1 progeny virion release by cell surface CD4 is relieved by expression of the viral Nef protein
-
Ross, T. M., A. E. Oran, and B. R. Cullen. 1999. Inhibition of HIV-1 progeny virion release by cell surface CD4 is relieved by expression of the viral Nef protein. Curr. Biol. 9:613-621.
-
(1999)
Curr. Biol.
, vol.9
, pp. 613-621
-
-
Ross, T.M.1
Oran, A.E.2
Cullen, B.R.3
-
62
-
-
0031979771
-
Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor
-
Salvi, R., A. R. Garbuglia, A. Di Caro, S. Pulciani, F. Montella, and A. Benedetto. 1998. Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor. J. Virol. 72: 3646-3657.
-
(1998)
J. Virol.
, vol.72
, pp. 3646-3657
-
-
Salvi, R.1
Garbuglia, A.R.2
Di Caro, A.3
Pulciani, S.4
Montella, F.5
Benedetto, A.6
-
63
-
-
0030292953
-
Activation of PAK by HIV and SIV Nef: Importance for AIDS in rhesus macaques
-
Sawai, E. T., I. H. Khan, P. M. Montbriand, B. M. Peterlin, M. C. Cheng, and P. A. Luciw. 1996. Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques. Curr. Biol. 6:1519-1527.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1519-1527
-
-
Sawai, E.T.1
Khan, I.H.2
Montbriand, P.M.3
Peterlin, B.M.4
Cheng, M.C.5
Luciw, P.A.6
-
64
-
-
0035120461
-
Human immunodeficiency virus type I Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions
-
Schaeffer, E., R. Geleziunas, and W. C. Greene. 2001. Human immunodeficiency virus type I Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions. J. Virol. 75:2993-3000.
-
(2001)
J. Virol.
, vol.75
, pp. 2993-3000
-
-
Schaeffer, E.1
Geleziunas, R.2
Greene, W.C.3
-
65
-
-
0033529258
-
HIV-1 Nef increases T-cell activation in a stimulus-dependent manner
-
Schrager, J. A., and J. W. Marsh. 1999. HIV-1 Nef increases T-cell activation in a stimulus-dependent manner. Proc. Natl. Acad. Sci. USA 96:8167-8172.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8167-8172
-
-
Schrager, J.A.1
Marsh, J.W.2
-
66
-
-
0029045360
-
Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell
-
Schwartz, O., V. Marechal, O. Danos, and J. M. Heard. 1995. Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell. J. Virol. 69:93-100.
-
(1995)
J. Virol.
, vol.69
, pp. 93-100
-
-
Schwartz, O.1
Marechal, V.2
Danos, O.3
Heard, J.M.4
-
67
-
-
0029875421
-
Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein
-
Schwartz, O., V. Marechal, G. S. Le, F. Lemonnier, and J. M. Heard. 1996. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nat. Med. 2:338-342.
-
(1996)
Nat. Med.
, vol.2
, pp. 338-342
-
-
Schwartz, O.1
Marechal, V.2
Le, G.S.3
Lemonnier, F.4
Heard, J.M.5
-
68
-
-
0027533215
-
Altered T-cell activation and development in transgenic mice expressing the HIV-1 nef gene
-
Skowronski, J., D. Parks, and R. Mariani. 1993. Altered T-cell activation and development in transgenic mice expressing the HIV-1 nef gene. EMBO J. 12:703-713.
-
(1993)
EMBO J.
, vol.12
, pp. 703-713
-
-
Skowronski, J.1
Parks, D.2
Mariani, R.3
-
69
-
-
0027952787
-
The importance of Nef in the induction of HIV-1 replication from primary quiescent CD4 lymphocytes
-
Spina, C. A., T. J. Kwoh, M. Y. Chowers, J. C. Guatelli, and D. D. Richman. 1994. The importance of Nef in the induction of HIV-1 replication from primary quiescent CD4 lymphocytes. J. Exp. Med. 179:115-123.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 115-123
-
-
Spina, C.A.1
Kwoh, T.J.2
Chowers, M.Y.3
Guatelli, J.C.4
Richman, D.D.5
-
70
-
-
0035836367
-
HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway
-
Swann, S. A., M. Williams, C. M. Story., K. R. Bobbitt, R. Fleis, and K. L. Collins. 2001. HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway. Virology 282:267-277.
-
(2001)
Virology
, vol.282
, pp. 267-277
-
-
Swann, S.A.1
Williams, M.2
Story, C.M.3
Bobbitt, K.R.4
Fleis, R.5
Collins, K.L.6
-
71
-
-
17344373542
-
Evidence of Nef truncation in human immunodeficiency virus type 2 infection
-
Switzer, W. M., S. Wiktor, V. Soriano, A. Silva-Graga, K. Mansinho, I. M. Coulibaly, E. Ekpini, A. E. Greenberg, T. M. Folks, and W. Heneine. 1998. Evidence of Nef truncation in human immunodeficiency virus type 2 infection. J. Infect. Dis. 177:65-71.
-
(1998)
J. Infect. Dis.
, vol.177
, pp. 65-71
-
-
Switzer, W.M.1
Wiktor, S.2
Soriano, V.3
Silva-Graga, A.4
Mansinho, K.5
Coulibaly, I.M.6
Ekpini, E.7
Greenberg, A.E.8
Folks, T.M.9
Heneine, W.10
-
72
-
-
0034602776
-
The Nef protein of HIV-1 associates with rafts and primes T cells for activation
-
Wang, J. K., E. Kiyokawa, E. Verdin, and D. Trono. 2000. The Nef protein of HIV-1 associates with rafts and primes T cells for activation. Proc. Natl. Acad. Sci. USA 97:394-399.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 394-399
-
-
Wang, J.K.1
Kiyokawa, E.2
Verdin, E.3
Trono, D.4
-
73
-
-
0030273317
-
HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis
-
Wiskerchen, M., and M. C. Cheng. 1996. HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis. Virology 224:292-301.
-
(1996)
Virology
, vol.224
, pp. 292-301
-
-
Wiskerchen, M.1
Cheng, M.C.2
-
74
-
-
0035811040
-
Nef increases infectivity of HIV via lipid rafts
-
Zheng, Y., A. Plemenitas, T. Linnemann, O. T. Fackler, and B. M. Peterlin. 2001. Nef increases infectivity of HIV via lipid rafts. Curr. Biol. 11:875-879.
-
(2001)
Curr. Biol.
, vol.11
, pp. 875-879
-
-
Zheng, Y.1
Plemenitas, A.2
Linnemann, T.3
Fackler, O.T.4
Peterlin, B.M.5
|