Disrupting surfaces of Nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo

Journal of Virology

Volumn 74, Issue 21, 2000, Pages 9836-9844

  Iafrate, A J ^a   Carl, S ^a   Bronson, S ^a   Stahl Hennig, C ^a   Swigut, T ^a   Skowronski, J ^a   Kirchhoff, F ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEF PROTEIN; VIRUS DNA; VIRUS PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL MODEL; ARTICLE; DOWN REGULATION; LEUKOCYTE COUNT; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRION; VIRUS INFECTION; VIRUS LOAD; VIRUS REPLICATION;

AMINO ACID SUBSTITUTION; ANIMAL; ANTIGENS, CD4; DOWN-REGULATION; GENE PRODUCTS, NEF; MACACA MULATTA; MUTATION; SEQUENCE ANALYSIS, DNA; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIV; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; VIRAL LOAD; VIRION; VIRULENCE; VIRUS REPLICATION;

EID: 0033775488     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.21.9836-9844.2000     Document Type: Article

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