-
1
-
-
1542514021
-
Discovery of new G protein-coupled receptors for lipid mediators
-
Im D.S. Discovery of new G protein-coupled receptors for lipid mediators. J Lipid Res 45 3 (2004) 410-418
-
(2004)
J Lipid Res
, vol.45
, Issue.3
, pp. 410-418
-
-
Im, D.S.1
-
2
-
-
25144483917
-
GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release
-
Filardo E.J., and Thomas P. GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release. Trends Endocrinol Metab 16 8 (2005) 362-367
-
(2005)
Trends Endocrinol Metab
, vol.16
, Issue.8
, pp. 362-367
-
-
Filardo, E.J.1
Thomas, P.2
-
3
-
-
0036432845
-
Identification of membrane-type receptor for bile acids (M-BAR)
-
Maruyama T., Miyamoto Y., Nakamura T., et al. Identification of membrane-type receptor for bile acids (M-BAR). Biochem Biophys Res Commun 298 5 (2002) 714-719
-
(2002)
Biochem Biophys Res Commun
, vol.298
, Issue.5
, pp. 714-719
-
-
Maruyama, T.1
Miyamoto, Y.2
Nakamura, T.3
-
4
-
-
0003269455
-
A G protein-coupled receptor responsive to bile acids
-
Kawamata Y., Fujii R., Hosoya M., et al. A G protein-coupled receptor responsive to bile acids. J Biol Chem 278 11 (2003) 9435-9440
-
(2003)
J Biol Chem
, vol.278
, Issue.11
, pp. 9435-9440
-
-
Kawamata, Y.1
Fujii, R.2
Hosoya, M.3
-
5
-
-
39749097760
-
GPR30: a novel therapeutic target in estrogen-related disease
-
Prossnitz E.R., Sklar L.A., Oprea T.I., and Arterburn J.B. GPR30: a novel therapeutic target in estrogen-related disease. Trends Pharmacol Sci 29 3 (2008) 116-123
-
(2008)
Trends Pharmacol Sci
, vol.29
, Issue.3
, pp. 116-123
-
-
Prossnitz, E.R.1
Sklar, L.A.2
Oprea, T.I.3
Arterburn, J.B.4
-
7
-
-
0037422595
-
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist
-
McIntyre T.M., Pontsler A.V., Silva A.R., et al. Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist. Proc Natl Acad Sci USA 100 1 (2003) 131-136
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.1
, pp. 131-136
-
-
McIntyre, T.M.1
Pontsler, A.V.2
Silva, A.R.3
-
8
-
-
27944458624
-
GPCR agonists and antagonists in the clinic
-
Tyndall J.D., and Sandilya R. GPCR agonists and antagonists in the clinic. Med Chem 1 4 (2005) 405-421
-
(2005)
Med Chem
, vol.1
, Issue.4
, pp. 405-421
-
-
Tyndall, J.D.1
Sandilya, R.2
-
9
-
-
0037446894
-
The G protein-coupled receptor repertoires of human and mouse
-
Vassilatis D.K., Hohmann J.G., Zeng H., et al. The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci USA 100 8 (2003) 4903-4908
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.8
, pp. 4903-4908
-
-
Vassilatis, D.K.1
Hohmann, J.G.2
Zeng, H.3
-
10
-
-
0036804995
-
Orphan G protein-coupled receptors and beyond
-
Im D.S. Orphan G protein-coupled receptors and beyond. Jpn J Pharmacol 90 2 (2002) 101-106
-
(2002)
Jpn J Pharmacol
, vol.90
, Issue.2
, pp. 101-106
-
-
Im, D.S.1
-
11
-
-
65249119361
-
Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation
-
Shimizu T. Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation. Annu Rev Pharmacol Toxicol 49 (2009) 123-150
-
(2009)
Annu Rev Pharmacol Toxicol
, vol.49
, pp. 123-150
-
-
Shimizu, T.1
-
12
-
-
33947427567
-
Lysophospholipid receptors: signalling, pharmacology and regulation by lysophospholipid metabolism
-
Meyer zu Heringdorf D., and Jakobs K.H. Lysophospholipid receptors: signalling, pharmacology and regulation by lysophospholipid metabolism. Biochim Biophys Acta 1768 4 (2007) 923-940
-
(2007)
Biochim Biophys Acta
, vol.1768
, Issue.4
, pp. 923-940
-
-
Meyer zu Heringdorf, D.1
Jakobs, K.H.2
-
13
-
-
23044438288
-
A short guide to the nomenclature of seven-transmembrane spanning receptors for lipid mediators
-
Howlett A.C. A short guide to the nomenclature of seven-transmembrane spanning receptors for lipid mediators. Life Sci 77 14 (2005) 1522-1530
-
(2005)
Life Sci
, vol.77
, Issue.14
, pp. 1522-1530
-
-
Howlett, A.C.1
-
14
-
-
3042856569
-
A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands
-
Kostenis E. A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands. Pharmacol Ther 102 3 (2004) 243-257
-
(2004)
Pharmacol Ther
, vol.102
, Issue.3
, pp. 243-257
-
-
Kostenis, E.1
-
15
-
-
53849134126
-
Eicosanoids in asthma, allergic inflammation, and host defense
-
Boyce J.A. Eicosanoids in asthma, allergic inflammation, and host defense. Curr Mol Med 8 5 (2008) 335-349
-
(2008)
Curr Mol Med
, vol.8
, Issue.5
, pp. 335-349
-
-
Boyce, J.A.1
-
16
-
-
54549108771
-
Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases
-
Calder P.C. Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases. Mol Nutr Food Res 52 8 (2008) 885-897
-
(2008)
Mol Nutr Food Res
, vol.52
, Issue.8
, pp. 885-897
-
-
Calder, P.C.1
-
17
-
-
36749072778
-
The multi-functional role of sphingosylphosphorylcholine
-
Nixon G.F., Mathieson F.A., and Hunter I. The multi-functional role of sphingosylphosphorylcholine. Prog Lipid Res 47 1 (2008) 62-75
-
(2008)
Prog Lipid Res
, vol.47
, Issue.1
, pp. 62-75
-
-
Nixon, G.F.1
Mathieson, F.A.2
Hunter, I.3
-
18
-
-
34447315542
-
Bacterial-induced hepoxilin A3 secretion as a pro-inflammatory mediator
-
McCormick B.A. Bacterial-induced hepoxilin A3 secretion as a pro-inflammatory mediator. Febs J 274 14 (2007) 3513-3518
-
(2007)
Febs J
, vol.274
, Issue.14
, pp. 3513-3518
-
-
McCormick, B.A.1
-
20
-
-
39449124119
-
Bile acids and the membrane bile acid receptor TGR5-connecting nutrition and metabolism
-
Thomas C., Auwerx J., and Schoonjans K. Bile acids and the membrane bile acid receptor TGR5-connecting nutrition and metabolism. Thyroid 18 2 (2008) 167-174
-
(2008)
Thyroid
, vol.18
, Issue.2
, pp. 167-174
-
-
Thomas, C.1
Auwerx, J.2
Schoonjans, K.3
-
21
-
-
0032823306
-
Prostanoid receptors: structures, properties, and functions
-
Narumiya S., Sugimoto Y., and Ushikubi F. Prostanoid receptors: structures, properties, and functions. Physiol Rev 79 4 (1999) 1193-1226
-
(1999)
Physiol Rev
, vol.79
, Issue.4
, pp. 1193-1226
-
-
Narumiya, S.1
Sugimoto, Y.2
Ushikubi, F.3
-
22
-
-
0037372846
-
International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors
-
Brink C., Dahlen S.E., Drazen J., et al. International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors. Pharmacol Rev 55 1 (2003) 195-227
-
(2003)
Pharmacol Rev
, vol.55
, Issue.1
, pp. 195-227
-
-
Brink, C.1
Dahlen, S.E.2
Drazen, J.3
-
23
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda L.A., Lolait S.J., Brownstein M.J., Young A.C., and Bonner T.I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346 6284 (1990) 561-564
-
(1990)
Nature
, vol.346
, Issue.6284
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
24
-
-
0036266101
-
International Union of Pharmacology XXXIV. Lysophospholipid receptor nomenclature
-
Chun J., Goetzl E.J., Hla T., et al. International Union of Pharmacology XXXIV. Lysophospholipid receptor nomenclature. Pharmacol Rev 54 2 (2002) 265-269
-
(2002)
Pharmacol Rev
, vol.54
, Issue.2
, pp. 265-269
-
-
Chun, J.1
Goetzl, E.J.2
Hla, T.3
-
25
-
-
29044447488
-
Two ligands for a GPCR, proton vs lysolipid
-
Im D.S. Two ligands for a GPCR, proton vs lysolipid. Acta Pharmacol Sin 26 12 (2005) 1435-1441
-
(2005)
Acta Pharmacol Sin
, vol.26
, Issue.12
, pp. 1435-1441
-
-
Im, D.S.1
-
26
-
-
24344474845
-
Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: a novel type of multi-functional receptors
-
Tomura H., Mogi C., Sato K., and Okajima F. Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: a novel type of multi-functional receptors. Cell Signal 17 12 (2005) 1466-1476
-
(2005)
Cell Signal
, vol.17
, Issue.12
, pp. 1466-1476
-
-
Tomura, H.1
Mogi, C.2
Sato, K.3
Okajima, F.4
-
27
-
-
27344451242
-
Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation
-
Mogi C., Tomura H., Tobo M., et al. Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation. J Pharmacol Sci 99 2 (2005) 160-167
-
(2005)
J Pharmacol Sci
, vol.99
, Issue.2
, pp. 160-167
-
-
Mogi, C.1
Tomura, H.2
Tobo, M.3
-
28
-
-
8544247246
-
TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor
-
Wang J.Q., Kon J., Mogi C., et al. TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor. J Biol Chem 279 44 (2004) 45626-45633
-
(2004)
J Biol Chem
, vol.279
, Issue.44
, pp. 45626-45633
-
-
Wang, J.Q.1
Kon, J.2
Mogi, C.3
-
29
-
-
13444250893
-
Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells
-
Radu C.G., Nijagal A., McLaughlin J., Wang L., and Witte O.N. Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. Proc Natl Acad Sci USA 102 5 (2005) 1632-1637
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.5
, pp. 1632-1637
-
-
Radu, C.G.1
Nijagal, A.2
McLaughlin, J.3
Wang, L.4
Witte, O.N.5
-
30
-
-
5644250571
-
G2A is a proton-sensing G-protein coupled receptor antagonized by lysophosphatidylcholine
-
Murakami N., Yokomizo T., Okuno T., and Shimizu T. G2A is a proton-sensing G-protein coupled receptor antagonized by lysophosphatidylcholine. J Biol Chem 279 41 (2004) 42484-42491
-
(2004)
J Biol Chem
, vol.279
, Issue.41
, pp. 42484-42491
-
-
Murakami, N.1
Yokomizo, T.2
Okuno, T.3
Shimizu, T.4
-
31
-
-
41949104092
-
Migration to apoptotic "find-me" signals is mediated via the phagocyte receptor G2A
-
Peter C., Waibel M., Radu C.G., et al. Migration to apoptotic "find-me" signals is mediated via the phagocyte receptor G2A. J Biol Chem 283 9 (2008) 5296-5305
-
(2008)
J Biol Chem
, vol.283
, Issue.9
, pp. 5296-5305
-
-
Peter, C.1
Waibel, M.2
Radu, C.G.3
-
32
-
-
34247579208
-
Upregulation of endothelial adhesion molecules by lysophosphatidylcholine. Involvement of G protein-coupled receptor GPR4
-
Zou Y., Kim C.H., Chung J.H., et al. Upregulation of endothelial adhesion molecules by lysophosphatidylcholine. Involvement of G protein-coupled receptor GPR4. Febs J 274 10 (2007) 2573-2584
-
(2007)
Febs J
, vol.274
, Issue.10
, pp. 2573-2584
-
-
Zou, Y.1
Kim, C.H.2
Chung, J.H.3
-
33
-
-
34249849671
-
A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration
-
Huang F., Mehta D., Predescu S., Kim K.S., and Lum H. A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration. Endothelium 14 1 (2007) 25-34
-
(2007)
Endothelium
, vol.14
, Issue.1
, pp. 25-34
-
-
Huang, F.1
Mehta, D.2
Predescu, S.3
Kim, K.S.4
Lum, H.5
-
34
-
-
33745686063
-
Lysophosphatidylcholine impairs endothelial barrier function through the G protein-coupled receptor GPR4
-
Qiao J., Huang F., Naikawadi R.P., Kim K.S., Said T., and Lum H. Lysophosphatidylcholine impairs endothelial barrier function through the G protein-coupled receptor GPR4. Am J Physiol Lung Cell Mol Physiol 291 1 (2006) L91-101
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
, Issue.1
-
-
Qiao, J.1
Huang, F.2
Naikawadi, R.P.3
Kim, K.S.4
Said, T.5
Lum, H.6
-
35
-
-
20944433323
-
GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine
-
Kim K.S., Ren J., Jiang Y., et al. GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine. Faseb J 19 7 (2005) 819-821
-
(2005)
Faseb J
, vol.19
, Issue.7
, pp. 819-821
-
-
Kim, K.S.1
Ren, J.2
Jiang, Y.3
-
36
-
-
34250680538
-
Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms
-
Tobo M., Tomura H., Mogi C., et al. Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms. Cell Signal 19 8 (2007) 1745-1753
-
(2007)
Cell Signal
, vol.19
, Issue.8
, pp. 1745-1753
-
-
Tobo, M.1
Tomura, H.2
Mogi, C.3
-
37
-
-
33846912184
-
Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor
-
Yang L.V., Radu C.G., Roy M., et al. Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor. Mol Cell Biol 27 4 (2007) 1334-1347
-
(2007)
Mol Cell Biol
, vol.27
, Issue.4
, pp. 1334-1347
-
-
Yang, L.V.1
Radu, C.G.2
Roy, M.3
-
39
-
-
46249108801
-
2 production in response to acidic pH through OGR1 in a human osteoblastic cell line
-
2 production in response to acidic pH through OGR1 in a human osteoblastic cell line. J Bone Miner Res 23 7 (2008) 1129-1139
-
(2008)
J Bone Miner Res
, vol.23
, Issue.7
, pp. 1129-1139
-
-
Tomura, H.1
Wang, J.Q.2
Liu, J.P.3
-
40
-
-
37349122826
-
Extracellular acidification enhances osteoclast survival through an NFAT-independent, protein kinase C-dependent pathway
-
Pereverzev A., Komarova S.V., Korcok J., et al. Extracellular acidification enhances osteoclast survival through an NFAT-independent, protein kinase C-dependent pathway. Bone 42 1 (2008) 150-161
-
(2008)
Bone
, vol.42
, Issue.1
, pp. 150-161
-
-
Pereverzev, A.1
Komarova, S.V.2
Korcok, J.3
-
41
-
-
58649100005
-
Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1
-
Frick K.K., Krieger N.S., Nehrke K., and Bushinsky D.A. Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. J Bone Miner Res 24 (2009) 305-313
-
(2009)
J Bone Miner Res
, vol.24
, pp. 305-313
-
-
Frick, K.K.1
Krieger, N.S.2
Nehrke, K.3
Bushinsky, D.A.4
-
42
-
-
27144487492
-
2 production and cAMP accumulation in response to acidic extracellular pH through OGR1 in human aortic smooth muscle cells
-
2 production and cAMP accumulation in response to acidic extracellular pH through OGR1 in human aortic smooth muscle cells. J Biol Chem 280 41 (2005) 34458-34464
-
(2005)
J Biol Chem
, vol.280
, Issue.41
, pp. 34458-34464
-
-
Tomura, H.1
Wang, J.Q.2
Komachi, M.3
-
44
-
-
28844451017
-
Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A
-
Obinata H., Hattori T., Nakane S., Tatei K., and Izumi T. Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A. J Biol Chem 280 49 (2005) 40676-40683
-
(2005)
J Biol Chem
, vol.280
, Issue.49
, pp. 40676-40683
-
-
Obinata, H.1
Hattori, T.2
Nakane, S.3
Tatei, K.4
Izumi, T.5
-
46
-
-
69549108246
-
G2A and LPC: regulatory functions in adaptive immunity
-
Kabarowski J.H.S. G2A and LPC: regulatory functions in adaptive immunity. Prostaglandins Other Lipid Mediat 89 (2009) 73-81
-
(2009)
Prostaglandins Other Lipid Mediat
, vol.89
, pp. 73-81
-
-
Kabarowski, J.H.S.1
-
47
-
-
0029162147
-
Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase
-
Eggerickx D., Denef J.F., Labbe O., et al. Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase. Biochem J 309 Pt 3 (1995) 837-843
-
(1995)
Biochem J
, vol.309
, Issue.PART 3
, pp. 837-843
-
-
Eggerickx, D.1
Denef, J.F.2
Labbe, O.3
-
48
-
-
0036828332
-
Sphingosine 1-phosphate is a ligand of the human GPR3, GPR6 and GPR12 family of constitutively active G protein-coupled receptors
-
Uhlenbrock K., Gassenhuber H., and Kostenis E. Sphingosine 1-phosphate is a ligand of the human GPR3, GPR6 and GPR12 family of constitutively active G protein-coupled receptors. Cell Signal 14 11 (2002) 941-953
-
(2002)
Cell Signal
, vol.14
, Issue.11
, pp. 941-953
-
-
Uhlenbrock, K.1
Gassenhuber, H.2
Kostenis, E.3
-
49
-
-
0037321393
-
Role of the G-protein-coupled receptor GPR12 as high-affinity receptor for sphingosylphosphorylcholine and its expression and function in brain development
-
Ignatov A., Lintzel J., Hermans-Borgmeyer I., et al. Role of the G-protein-coupled receptor GPR12 as high-affinity receptor for sphingosylphosphorylcholine and its expression and function in brain development. J Neurosci 23 3 (2003) 907-914
-
(2003)
J Neurosci
, vol.23
, Issue.3
, pp. 907-914
-
-
Ignatov, A.1
Lintzel, J.2
Hermans-Borgmeyer, I.3
-
51
-
-
4344577277
-
Identification of signal transduction pathways used by orphan G protein-coupled receptors
-
Bresnick J.N., Skynner H.A., Chapman K.L., et al. Identification of signal transduction pathways used by orphan G protein-coupled receptors. Assay Drug Dev Technol 1 2 (2003) 239-249
-
(2003)
Assay Drug Dev Technol
, vol.1
, Issue.2
, pp. 239-249
-
-
Bresnick, J.N.1
Skynner, H.A.2
Chapman, K.L.3
-
52
-
-
21144441406
-
Premature ovarian aging in mice deficient for GPR3
-
Ledent C., Demeestere I., Blum D., et al. Premature ovarian aging in mice deficient for GPR3. Proc Natl Acad Sci USA 102 25 (2005) 8922-8926
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.25
, pp. 8922-8926
-
-
Ledent, C.1
Demeestere, I.2
Blum, D.3
-
53
-
-
10344258606
-
3 maintains meiotic arrest in mammalian oocytes
-
3 maintains meiotic arrest in mammalian oocytes. Science 306 5703 (2004) 1947-1950
-
(2004)
Science
, vol.306
, Issue.5703
, pp. 1947-1950
-
-
Mehlmann, L.M.1
Saeki, Y.2
Tanaka, S.3
-
54
-
-
27744545587
-
The G-protein-coupled receptors GPR3 and GPR12 are involved in cAMP signaling and maintenance of meiotic arrest in rodent oocytes
-
Hinckley M., Vaccari S., Horner K., Chen R., and Conti M. The G-protein-coupled receptors GPR3 and GPR12 are involved in cAMP signaling and maintenance of meiotic arrest in rodent oocytes. Dev Biol 287 2 (2005) 249-261
-
(2005)
Dev Biol
, vol.287
, Issue.2
, pp. 249-261
-
-
Hinckley, M.1
Vaccari, S.2
Horner, K.3
Chen, R.4
Conti, M.5
-
55
-
-
0038152846
-
Identification of p2y9/GPR23 as a novel G protein-coupled receptor for Lysophosphatidic acid, structurally distant from the Edg family
-
Noguchi K., Ishii S., and Shimizu T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for Lysophosphatidic acid, structurally distant from the Edg family. J Biol Chem 278 (2003) 25600-25606
-
(2003)
J Biol Chem
, vol.278
, pp. 25600-25606
-
-
Noguchi, K.1
Ishii, S.2
Shimizu, T.3
-
58
-
-
33745957774
-
Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastro-intestinal lymphocytes
-
Kotarsky K., Boketoft A., Bristulf J., et al. Lysophosphatidic acid binds to and activates GPR92, a G protein-coupled receptor highly expressed in gastro-intestinal lymphocytes. J Pharmacol Exp Ther 318 2 (2006) 619-628
-
(2006)
J Pharmacol Exp Ther
, vol.318
, Issue.2
, pp. 619-628
-
-
Kotarsky, K.1
Boketoft, A.2
Bristulf, J.3
-
59
-
-
39749127777
-
G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth
-
Pasternack S.M., von Kugelgen I., Aboud K.A., et al. G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth. Nat Genet 40 3 (2008) 329-334
-
(2008)
Nat Genet
, vol.40
, Issue.3
, pp. 329-334
-
-
Pasternack, S.M.1
von Kugelgen, I.2
Aboud, K.A.3
-
60
-
-
34948889998
-
The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor
-
Tabata K., Baba K., Shiraishi A., Ito M., and Fujita N. The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor. Biochem Biophys Res Commun 363 3 (2007) 861-866
-
(2007)
Biochem Biophys Res Commun
, vol.363
, Issue.3
, pp. 861-866
-
-
Tabata, K.1
Baba, K.2
Shiraishi, A.3
Ito, M.4
Fujita, N.5
-
61
-
-
51049093412
-
Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92
-
Oh da Y., Yoon J.M., Moon M.J., et al. Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92. J Biol Chem 283 30 (2008) 21054-21064
-
(2008)
J Biol Chem
, vol.283
, Issue.30
, pp. 21054-21064
-
-
Oh da, Y.1
Yoon, J.M.2
Moon, M.J.3
-
62
-
-
69549085467
-
-
5. Prostaglandins Other Lipid Mediat 2009:88, in press.
-
5. Prostaglandins Other Lipid Mediat 2009:88, in press.
-
-
-
-
63
-
-
0037838892
-
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids
-
Briscoe C.P., Tadayyon M., Andrews J.L., et al. The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem 278 13 (2003) 11303-11311
-
(2003)
J Biol Chem
, vol.278
, Issue.13
, pp. 11303-11311
-
-
Briscoe, C.P.1
Tadayyon, M.2
Andrews, J.L.3
-
64
-
-
0037434991
-
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40
-
Itoh Y., Kawamata Y., Harada M., et al. Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature 422 6928 (2003) 173-176
-
(2003)
Nature
, vol.422
, Issue.6928
, pp. 173-176
-
-
Itoh, Y.1
Kawamata, Y.2
Harada, M.3
-
65
-
-
0038363378
-
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
-
Brown A.J., Goldsworthy S.M., Barnes A.A., et al. The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 278 13 (2003) 11312-11319
-
(2003)
J Biol Chem
, vol.278
, Issue.13
, pp. 11312-11319
-
-
Brown, A.J.1
Goldsworthy, S.M.2
Barnes, A.A.3
-
66
-
-
0038491435
-
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cells activation
-
Le Poul E., Loison C., Struyf S., et al. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cells activation. J Biol Chem 278 (2003) 25481-25489
-
(2003)
J Biol Chem
, vol.278
, pp. 25481-25489
-
-
Le Poul, E.1
Loison, C.2
Struyf, S.3
-
67
-
-
0037453280
-
Identification of a free fatty acid receptor, FFA(2)R, expressed on leukocytes and activated by short-chain fatty acids
-
Nilsson N.E., Kotarsky K., Owman C., and Olde B. Identification of a free fatty acid receptor, FFA(2)R, expressed on leukocytes and activated by short-chain fatty acids. Biochem Biophys Res Commun 303 4 (2003) 1047-1052
-
(2003)
Biochem Biophys Res Commun
, vol.303
, Issue.4
, pp. 1047-1052
-
-
Nilsson, N.E.1
Kotarsky, K.2
Owman, C.3
Olde, B.4
-
68
-
-
13444263540
-
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
-
Hirasawa A., Tsumaya K., Awaji T., et al. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med 11 1 (2005) 90-94
-
(2005)
Nat Med
, vol.11
, Issue.1
, pp. 90-94
-
-
Hirasawa, A.1
Tsumaya, K.2
Awaji, T.3
-
69
-
-
69549137171
-
Fatty acids receptors (GPR40, GPR41, GPR43 and GPR120)
-
in press
-
Tsujimoto G. Fatty acids receptors (GPR40, GPR41, GPR43 and GPR120). Prostaglandins Other Lipid Mediat 2009:88, in press.
-
(2009)
Prostaglandins Other Lipid Mediat
, pp. 88
-
-
Tsujimoto, G.1
-
70
-
-
12244280857
-
Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63
-
Niedernberg A., Tunaru S., Blaukat A., Ardati A., and Kostenis E. Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for the orphan receptor GPR63. Cell Signal 15 4 (2003) 435-446
-
(2003)
Cell Signal
, vol.15
, Issue.4
, pp. 435-446
-
-
Niedernberg, A.1
Tunaru, S.2
Blaukat, A.3
Ardati, A.4
Kostenis, E.5
-
71
-
-
32344443978
-
Identification of a lysophosphatidylserine receptor on mast cells
-
Sugo T., Tachimoto H., Chikatsu T., et al. Identification of a lysophosphatidylserine receptor on mast cells. Biochem Biophys Res Commun 341 4 (2006) 1078-1087
-
(2006)
Biochem Biophys Res Commun
, vol.341
, Issue.4
, pp. 1078-1087
-
-
Sugo, T.1
Tachimoto, H.2
Chikatsu, T.3
-
72
-
-
69549103075
-
Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine, and lysophosphatidylglyreol
-
in press
-
Makido K., Kitamura H., Sato Y., Okutani M., and Aoki J. Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine, and lysophosphatidylglyreol. Prostaglandins Other Lipid Mediat (2009) 88 in press
-
(2009)
Prostaglandins Other Lipid Mediat
, pp. 88
-
-
Makido, K.1
Kitamura, H.2
Sato, Y.3
Okutani, M.4
Aoki, J.5
-
73
-
-
33846493012
-
Effect of lysophosphatidylglycerol on several signaling molecules in OVCAR-3 human ovarian cancer cells: involvement of pertussis toxin-sensitive G-protein coupled receptor
-
Park K.S., Kim M.K., Im D.S., and Bae Y.S. Effect of lysophosphatidylglycerol on several signaling molecules in OVCAR-3 human ovarian cancer cells: involvement of pertussis toxin-sensitive G-protein coupled receptor. Biochem Pharmacol 73 5 (2007) 675-681
-
(2007)
Biochem Pharmacol
, vol.73
, Issue.5
, pp. 675-681
-
-
Park, K.S.1
Kim, M.K.2
Im, D.S.3
Bae, Y.S.4
-
74
-
-
34548442406
-
Lysophosphatidylethanolamine stimulates chemotactic migration and cellular invasion in SK-OV3 human ovarian cancer cells: involvement of pertussis toxin-sensitive G-protein coupled receptor
-
Park K.S., Lee H.Y., Lee S.Y., et al. Lysophosphatidylethanolamine stimulates chemotactic migration and cellular invasion in SK-OV3 human ovarian cancer cells: involvement of pertussis toxin-sensitive G-protein coupled receptor. FEBS Lett 581 23 (2007) 4411-4416
-
(2007)
FEBS Lett
, vol.581
, Issue.23
, pp. 4411-4416
-
-
Park, K.S.1
Lee, H.Y.2
Lee, S.Y.3
-
75
-
-
30344476972
-
In silico patent searching reveals a new cannabinoid receptor
-
Baker D., Pryce G., Davies W.L., and Hiley C.R. In silico patent searching reveals a new cannabinoid receptor. Trends Pharmacol Sci 27 1 (2006) 1-4
-
(2006)
Trends Pharmacol Sci
, vol.27
, Issue.1
, pp. 1-4
-
-
Baker, D.1
Pryce, G.2
Davies, W.L.3
Hiley, C.R.4
-
76
-
-
35648959293
-
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects
-
Johns D.G., Behm D.J., Walker D.J., et al. The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. Br J Pharmacol 152 5 (2007) 825-831
-
(2007)
Br J Pharmacol
, vol.152
, Issue.5
, pp. 825-831
-
-
Johns, D.G.1
Behm, D.J.2
Walker, D.J.3
-
77
-
-
35649015179
-
The orphan receptor GPR55 is a novel cannabinoid receptor
-
Ryberg E., Larsson N., Sjogren S., et al. The orphan receptor GPR55 is a novel cannabinoid receptor. Br J Pharmacol 152 7 (2007) 1092-1101
-
(2007)
Br J Pharmacol
, vol.152
, Issue.7
, pp. 1092-1101
-
-
Ryberg, E.1
Larsson, N.2
Sjogren, S.3
-
78
-
-
34548591720
-
Identification of GPR55 as a lysophosphatidylinositol receptor
-
Oka S., Nakajima K., Yamashita A., Kishimoto S., and Sugiura T. Identification of GPR55 as a lysophosphatidylinositol receptor. Biochem Biophys Res Commun 362 4 (2007) 928-934
-
(2007)
Biochem Biophys Res Commun
, vol.362
, Issue.4
, pp. 928-934
-
-
Oka, S.1
Nakajima, K.2
Yamashita, A.3
Kishimoto, S.4
Sugiura, T.5
-
79
-
-
58149138962
-
2-Arachidonoyl-sn-glycero-3-phosphoinositol: a possible natural ligand for GPR55
-
Oka S., Toshida T., Maruyama K., Nakajima K., Yamashita A., and Sugiura T. 2-Arachidonoyl-sn-glycero-3-phosphoinositol: a possible natural ligand for GPR55. J Biochem 145 1 (2009) 13-20
-
(2009)
J Biochem
, vol.145
, Issue.1
, pp. 13-20
-
-
Oka, S.1
Toshida, T.2
Maruyama, K.3
Nakajima, K.4
Yamashita, A.5
Sugiura, T.6
-
81
-
-
51549099779
-
The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain
-
Staton P.C., Hatcher J.P., Walker D.J., et al. The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain. Pain 139 1 (2008) 225-236
-
(2008)
Pain
, vol.139
, Issue.1
, pp. 225-236
-
-
Staton, P.C.1
Hatcher, J.P.2
Walker, D.J.3
-
82
-
-
40649102938
-
GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current
-
Lauckner J.E., Jensen J.B., Chen H.Y., Lu H.C., Hille B., and Mackie K. GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proc Natl Acad Sci USA 105 7 (2008) 2699-2704
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.7
, pp. 2699-2704
-
-
Lauckner, J.E.1
Jensen, J.B.2
Chen, H.Y.3
Lu, H.C.4
Hille, B.5
Mackie, K.6
-
85
-
-
10644275303
-
Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor
-
Soga T., Ohishi T., Matsui T., et al. Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor. Biochem Biophys Res Commun 326 4 (2005) 744-751
-
(2005)
Biochem Biophys Res Commun
, vol.326
, Issue.4
, pp. 744-751
-
-
Soga, T.1
Ohishi, T.2
Matsui, T.3
-
86
-
-
33644627958
-
Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents
-
Overton H.A., Babbs A.J., Doel S.M., et al. Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab 3 3 (2006) 167-175
-
(2006)
Cell Metab
, vol.3
, Issue.3
, pp. 167-175
-
-
Overton, H.A.1
Babbs, A.J.2
Doel, S.M.3
-
87
-
-
40349114501
-
GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity
-
Overton H.A., Fyfe M.C., and Reynet C. GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity. Br J Pharmacol 153 Suppl 1 (2008) S76-81
-
(2008)
Br J Pharmacol
, vol.153
, Issue.SUPPL. 1
-
-
Overton, H.A.1
Fyfe, M.C.2
Reynet, C.3
-
88
-
-
35748973885
-
Novel cannabinoid receptors
-
Brown A.J. Novel cannabinoid receptors. Br J Pharmacol 152 5 (2007) 567-575
-
(2007)
Br J Pharmacol
, vol.152
, Issue.5
, pp. 567-575
-
-
Brown, A.J.1
-
90
-
-
0037333994
-
Expression and characterization of a 5-oxo-6E, 8Z, 11Z, 14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils
-
Jones C.E., Holden S., Tenaillon L., et al. Expression and characterization of a 5-oxo-6E, 8Z, 11Z, 14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils. Mol Pharmacol 63 3 (2003) 471-477
-
(2003)
Mol Pharmacol
, vol.63
, Issue.3
, pp. 471-477
-
-
Jones, C.E.1
Holden, S.2
Tenaillon, L.3
-
91
-
-
23044469567
-
i/o-protein-coupled receptor, mediates 5-oxo-eicosatetraenoic acid-induced chemotaxis
-
i/o-protein-coupled receptor, mediates 5-oxo-eicosatetraenoic acid-induced chemotaxis. Biochem Biophys Res Commun 334 4 (2005) 987-995
-
(2005)
Biochem Biophys Res Commun
, vol.334
, Issue.4
, pp. 987-995
-
-
Hosoi, T.1
Sugikawa, E.2
Chikada, A.3
Koguchi, Y.4
Ohnuki, T.5
-
93
-
-
1542347126
-
International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor
-
Brink C., Dahlen S.E., Drazen J., et al. International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor. Pharmacol Rev 56 1 (2004) 149-157
-
(2004)
Pharmacol Rev
, vol.56
, Issue.1
, pp. 149-157
-
-
Brink, C.1
Dahlen, S.E.2
Drazen, J.3
-
94
-
-
42449096851
-
Structural requirements for activation of the 5-oxo-6E, 8Z, 11Z, 14Z-eicosatetraenoic acid (5-oxo-ETE) receptor: identification of a mead acid metabolite with potent agonist activity
-
Patel P., Cossette C., Anumolu J.R., et al. Structural requirements for activation of the 5-oxo-6E, 8Z, 11Z, 14Z-eicosatetraenoic acid (5-oxo-ETE) receptor: identification of a mead acid metabolite with potent agonist activity. J Pharmacol Exp Ther 325 2 (2008) 698-707
-
(2008)
J Pharmacol Exp Ther
, vol.325
, Issue.2
, pp. 698-707
-
-
Patel, P.1
Cossette, C.2
Anumolu, J.R.3
-
96
-
-
31444454037
-
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
-
Watanabe M., Houten S.M., Mataki C., et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 439 7075 (2006) 484-489
-
(2006)
Nature
, vol.439
, Issue.7075
, pp. 484-489
-
-
Watanabe, M.1
Houten, S.M.2
Mataki, C.3
-
97
-
-
48749113401
-
Targeting bile-acid signalling for metabolic diseases
-
Thomas C., Pellicciari R., Pruzanski M., Auwerx J., and Schoonjans K. Targeting bile-acid signalling for metabolic diseases. Nat Rev Drug Discov 7 8 (2008) 678-693
-
(2008)
Nat Rev Drug Discov
, vol.7
, Issue.8
, pp. 678-693
-
-
Thomas, C.1
Pellicciari, R.2
Pruzanski, M.3
Auwerx, J.4
Schoonjans, K.5
-
98
-
-
33751066787
-
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice
-
Maruyama T., Tanaka K., Suzuki J., et al. Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice. J Endocrinol 191 1 (2006) 197-205
-
(2006)
J Endocrinol
, vol.191
, Issue.1
, pp. 197-205
-
-
Maruyama, T.1
Tanaka, K.2
Suzuki, J.3
-
99
-
-
33748757234
-
Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation
-
Vassileva G., Golovko A., Markowitz L., et al. Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation. Biochem J 398 3 (2006) 423-430
-
(2006)
Biochem J
, vol.398
, Issue.3
, pp. 423-430
-
-
Vassileva, G.1
Golovko, A.2
Markowitz, L.3
-
101
-
-
42649089790
-
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
-
Serhan C.N., Chiang N., and Van Dyke T.E. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol 8 5 (2008) 349-361
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.5
, pp. 349-361
-
-
Serhan, C.N.1
Chiang, N.2
Van Dyke, T.E.3
-
102
-
-
0037152160
-
Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
-
Serhan C.N., Hong S., Gronert K., et al. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 196 8 (2002) 1025-1037
-
(2002)
J Exp Med
, vol.196
, Issue.8
, pp. 1025-1037
-
-
Serhan, C.N.1
Hong, S.2
Gronert, K.3
-
103
-
-
38649115964
-
Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells
-
Feltenmark S., Gautam N., Brunnstrom A., et al. Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells. Proc Natl Acad Sci USA 105 2 (2008) 680-685
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.2
, pp. 680-685
-
-
Feltenmark, S.1
Gautam, N.2
Brunnstrom, A.3
-
104
-
-
69549086392
-
Omega-3 PUFA derived anti-inflammatory lipid mediator resolving E1
-
in press
-
Seki H., Tani Y., and Arita M. Omega-3 PUFA derived anti-inflammatory lipid mediator resolving E1. Prostaglandins Other Lipid Mediat (2009) 88 in press
-
(2009)
Prostaglandins Other Lipid Mediat
, pp. 88
-
-
Seki, H.1
Tani, Y.2
Arita, M.3
-
105
-
-
69549108552
-
On the biosynthesis and biological role of eoxins and 15-lipoxygenase-1 in airway inflammation and Hodgkin lymphoma
-
Claesson H.E. On the biosynthesis and biological role of eoxins and 15-lipoxygenase-1 in airway inflammation and Hodgkin lymphoma. Prostaglandins Other Lipid Mediat 89 (2009) 120-125
-
(2009)
Prostaglandins Other Lipid Mediat
, vol.89
, pp. 120-125
-
-
Claesson, H.E.1
-
106
-
-
45749119935
-
N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons
-
Rimmerman N., Bradshaw H.B., Hughes H.V., et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol 74 1 (2008) 213-224
-
(2008)
Mol Pharmacol
, vol.74
, Issue.1
, pp. 213-224
-
-
Rimmerman, N.1
Bradshaw, H.B.2
Hughes, H.V.3
-
107
-
-
34047158227
-
Potential anti-inflammatory actions of the elmiric (lipoamino) acids
-
Burstein S.H., Adams J.K., Bradshaw H.B., et al. Potential anti-inflammatory actions of the elmiric (lipoamino) acids. Bioorg Med Chem 15 10 (2007) 3345-3355
-
(2007)
Bioorg Med Chem
, vol.15
, Issue.10
, pp. 3345-3355
-
-
Burstein, S.H.1
Adams, J.K.2
Bradshaw, H.B.3
-
108
-
-
33746401106
-
Targeted lipidomics: discovery of new fatty acyl amides
-
Tan B., Bradshaw H.B., Rimmerman N., et al. Targeted lipidomics: discovery of new fatty acyl amides. Aaps J 8 3 (2006) E461-E465
-
(2006)
Aaps J
, vol.8
, Issue.3
-
-
Tan, B.1
Bradshaw, H.B.2
Rimmerman, N.3
-
111
-
-
77955799815
-
Oral fingolimod (FTY720) for relapsing multiple sclerosis
-
Kappos L., Antel J., Comi G., et al. Oral fingolimod (FTY720) for relapsing multiple sclerosis. N Engl J Med 355 11 (2006) 1124-1140
-
(2006)
N Engl J Med
, vol.355
, Issue.11
, pp. 1124-1140
-
-
Kappos, L.1
Antel, J.2
Comi, G.3
-
112
-
-
43249119649
-
FTY720 (fingolimod) for relapsing multiple sclerosis
-
Horga A., and Montalban X. FTY720 (fingolimod) for relapsing multiple sclerosis. Expert Rev Neurother 8 5 (2008) 699-714
-
(2008)
Expert Rev Neurother
, vol.8
, Issue.5
, pp. 699-714
-
-
Horga, A.1
Montalban, X.2
|