Extracellular acidification enhances osteoclast survival through an NFAT-independent, protein kinase C-dependent pathway

Bone

Volumn 42, Issue 1, 2008, Pages 150-161

  Pereverzev, Alexey ^a   Komarova, Svetlana V ^b   Korčok, Jasminka ^a   Armstrong, Souzan ^a   Tremblay, Gilles B ^c   Dixon, S Jeffrey ^a   Sims, Stephen M ^a  

^a WESTERN UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c Alethia BioTherapeutics Incorporated   (Canada)

Author keywords

Acidosis; Apoptosis; Bone resorption; Cytosolic calcium; Ovarian cancer G protein coupled receptor 1 (OGR1)

Indexed keywords

AMINO ACID DERIVATIVE; ARGINYLARGINYLARGINYLARGINYLARGINYLARGINYLARGINYLARGINYLARGINYL ARGINYLARGINYLGLYCYLGLYCYLGLYCYLMETHIONYLALANYLGLYCYLPROLYLHISTIDYL PROLYLVALYLISOLEUCYLVALYLISOLEUCYLTHREONYLGLYCYLPROLYLHISTIDYLGLUTAMYLGLUTAMINE; CUPRIC ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FURA 2; G PROTEIN COUPLED RECEPTOR; OSTEOCLAST DIFFERENTIATION FACTOR; OVARIAN CANCER G PROTEIN COUPLED RECEPTOR 1; PROTEIN KINASE C; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ACIDIFICATION; ACIDOSIS; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL ISOLATION; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CHELATION; CYTOSOL; ENZYME INHIBITION; GENETIC TRANSCRIPTION; LONG BONE; MOUSE; MULTINUCLEAR CELL; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOCLAST; OSTEOLYSIS; PH; PROTEIN DEPLETION; PROTEIN FUNCTION; RAT; RNA INTERFERENCE;

ACIDS; ANIMALS; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; ENZYME ACTIVATION; EXTRACELLULAR SPACE; HYDROGEN-ION CONCENTRATION; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NFATC TRANSCRIPTION FACTORS; OSTEOCLASTS; PROTEIN KINASE C; RATS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 37349122826     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2007.08.044     Document Type: Article

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