On the biosynthesis and biological role of eoxins and 15-lipoxygenase-1 in airway inflammation and Hodgkin lymphoma

Prostaglandins and Other Lipid Mediators

Volumn 89, Issue 3-4, 2009, Pages 120-125

  Claesson, Hans Erik ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

12 15 Lipoxygenase; 15 HETE; Arachidonic acid; Eosinophils; L1236

Indexed keywords

15 LIPOXYGENASE 1; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONIC ACID; EOXIN DERIVATIVE; LIPOXIN; UNCLASSIFIED DRUG;

ASTHMA; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHRONIC OBSTRUCTIVE LUNG DISEASE; EOSINOPHIL; EPITHELIUM CELL; FATTY ACID SYNTHESIS; HODGKIN DISEASE; HUMAN; HUMAN CELL; MAST CELL; PATHOPHYSIOLOGY; PNEUMONIA; PROTEIN EXPRESSION; REVIEW; WILD TYPE;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; ASTHMA; EOSINOPHILS; HODGKIN DISEASE; HUMANS; INFLAMMATION; LEUKOTRIENE D4; LEUKOTRIENES; LUNG; MICE; ORGAN SPECIFICITY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REED-STERNBERG CELLS;

EID: 69549108552     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2008.12.003     Document Type: Review

References (58)

1. Claesson H.E., and Dahlen S.E. Asthma and leukotrienes: antileukotrienes as novel anti-asthmatic drugs. J Intern Med 245 3 (1999) 205-227
2. Johnson E.N., Brass L.F., and Funk C.D. Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase. Proc Natl Acad Sci USA 95 6 (1998) 3100-3105
3. Brash A.R., Boeglin W.E., and Chang M.S. Discovery of a second 15S-lipoxygenase in humans. Proc Natl Acad Sci USA 94 12 (1997) 6148-6152
4. Kuhn H., and O'Donnell V.B. Inflammation and immune regulation by 12/15-lipoxygenases. Prog Lipid Res 45 4 (2006) 334-356
5. Kuhn H., Heydeck D., Brinckman R., and Trebus F. Regulation of cellular 15-lipoxygenase activity on pretranslational, translational, and posttranslational levels. Lipids 34 Suppl (1999) S273-S279
6. Liu C., Xu D., Sjoberg J., Forsell P., Bjorkholm M., and Claesson H.E. Transcriptional regulation of 15-lipoxygenase expression by promoter methylation. Exp Cell Res 297 1 (2004) 61-67
7. Zuo X., Morris J.S., and Shureiqi I. Chromatin modification requirements for 15-lipoxygenase-1 transcriptional reactivation in colon cancer cells. J Biol Chem 283 46 (2008) 31341-31347
8. Kuhn H., Walther M., and Kuban R.J. Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications. Prostaglandins Other Lipid Mediat 68-69 (2002) 263-290
9. Conrad D.J., Kuhn H., Mulkins M., Highland E., and Sigal E. Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase. Proc Natl Acad Sci USA 89 1 (1992) 217-221
10. Brinckmann R., Topp M.S., Zalan I., et al. Regulation of 15-lipoxygenase expression in lung epithelial cells by interleukin-4. Biochem J 318 Pt 1 (1996) 305-312
11. Gulliksson M., Brunnstrom A., Johannesson M., et al. Expression of 15-lipoxygenase type-1 in human mast cells. Biochim Biophys Acta 1771 9 (2007) 1156-1165
12. Shannon V.R., Chanez P., Bousquet J., and Holtzman M.J. Histochemical evidence for induction of arachidonate 15-lipoxygenase in airway disease. Am Rev Respir Dis 147 4 (1993) 1024-1028
13. Chu H.W., Balzar S., Westcott J.Y., et al. Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition. Clin Exp Allergy 32 11 (2002) 1558-1565
14. Laprise C., Sladek R., Ponton A., Bernier M.C., Hudson T.J., and Laviolette M. Functional classes of bronchial mucosa genes that are differentially expressed in asthma. BMC Genomics 5 1 (2004) 21
15. Zhu J., Kilty I., Granger H., et al. Gene expression and immunolocalization of 15-lipoxygenase isozymes in the airway mucosa of smokers with chronic bronchitis. Am J Respir Cell Mol Biol 27 6 (2002) 666-677
16. Kumlin M., Hamberg M., Granstrom E., et al. 15(S)-hydroxyeicosatetraenoic acid is the major arachidonic acid metabolite in human bronchi: association with airway epithelium. Arch Biochem Biophys 282 2 (1990) 254-262
17. Koskela H., Di Sciascio M.B., Anderson S.D., et al. Nasal hyperosmolar challenge with a dry powder of mannitol in patients with allergic rhinitis. Evidence for epithelial cell involvement. Clin Exp Allergy 30 11 (2000) 1627-1636
18. Schwenk U., Morita E., Engel R., and Schroder J.M. Identification of 5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid as a novel and potent human eosinophil chemotactic eicosanoid. J Biol Chem 267 18 (1992) 12482-12488
19. Serhan C.N. Lipoxin biosynthesis and its impact in inflammatory and vascular events. Biochim Biophys Acta 1212 1 (1994) 1-25
20. Yao Y., Clark C.M., Trojanowski J.Q., Lee V.M., and Pratico D. Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment. Ann Neurol 58 4 (2005) 623-626
21. Pratico D., Zhukareva V., Yao Y., et al. 12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress. Am J Pathol 164 5 (2004) 1655-1662
22. Cyrus T., Witztum J.L., Rader D.J., et al. Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. J Clin Invest 103 11 (1999) 1597-1604
23. Huo Y., Zhao L., Hyman M.C., et al. Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice. Circulation 110 14 (2004) 2024-2031
24. Spanbroek R., Grabner R., Lotzer K., et al. Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis. Proc Natl Acad Sci USA 100 3 (2003) 1238-1243
25. van Leyen K., Duvoisin R.M., Engelhardt H., and Wiedmann M. A function for lipoxygenase in programmed organelle degradation. Nature 395 6700 (1998) 392-395
26. Kelavkar U., Cohen C., Eling T., and Badr K. 15-lipoxygenase-1 overexpression in prostate adenocarcinoma. Adv Exp Med Biol 507 (2002) 133-145
27. Turk J., Maas R.L., Brash A.R., Roberts II L.J., and Oates J.A. Arachidonic acid 15-lipoxygenase products from human eosinophils. J Biol Chem 257 12 (1982) 7068-7076
28. Feltenmark S., Gautam N., Brunnstrom A., et al. Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells. Proc Natl Acad Sci USA 105 2 (2008) 680-685
29. Hunter J.A., Finkbeiner W.E., Nadel J.A., Goetzl E.J., and Holtzman M.J. Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea. Proc Natl Acad Sci USA 82 14 (1985) 4633-4637
30. Gautam N., Hedqvist P., and Lindbom L. Kinetics of leukocyte-induced changes in endothelial barrier function. Br J Pharmacol 125 5 (1998) 1109-1114
31. Turk J., Rand T.H., Maas R.L., et al. Identification of lipoxygenase products from arachidonic acid metabolism in stimulated murine eosinophils. Biochim Biophys Acta 750 1 (1983) 78-90
32. Shannon V.R., Crouch E.C., Takahashi Y., Ueda N., Yamamoto S., and Holtzman M.J. Related expression of arachidonate 12- and 15-lipoxygenases in animal and human lung tissue. Am J Physiol 261 6 Pt 1 (1991) L399-L405
33. Kuperman D.A., Lewis C.C., Woodruff P.G., et al. Dissecting asthma using focused transgenic modeling and functional genomics. J Allergy Clin Immunol 116 2 (2005) 305-311
34. Andersson C.K., Claesson H.E., Rydell-Tormanen K., Swedmark S., Hallgren A., and Erjefalt J.S. Mice lacking 12/15-lipoxygenase have attenuated airway allergic inflammation and remodeling. Am J Respir Cell Mol Biol 39 6 (2008) 648-656
35. Li S.L., Dwarakanath R.S., Cai Q., Lanting L., and Natarajan R. Effects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAs. J Lipid Res 46 2 (2005) 220-229
36. Wen Y., Gu J., Chakrabarti S.K., et al. The role of 12/15-lipoxygenase in the expression of interleukin-6 and tumor necrosis factor-alpha in macrophages. Endocrinology 148 3 (2007) 1313-1322
37. Brauninger A., Schmitz R., Bechtel D., Renne C., Hansmann M.L., and Kuppers R. Molecular biology of Hodgkin's and Reed/Sternberg cells in Hodgkin's lymphoma. Int J Cancer 118 8 (2006) 1853-1861
38. Re D., Kuppers R., and Diehl V. Molecular pathogenesis of Hodgkin's lymphoma. J Clin Oncol 23 26 (2005) 6379-6386
39. Poppema S., and van den Berg A. Interaction between host T cells and Reed-Sternberg cells in Hodgkin lymphomas. Semin Cancer Biol 10 5 (2000) 345-350
40. Claesson H.E., Griffiths W.J., Brunnstrom A., et al. Hodgkin Reed-Sternberg cells express 15-lipoxygenase-1 and are putative producers of eoxins in vivo: novel insight into the inflammatory features of classical Hodgkin lymphoma. Febs J 275 16 (2008) 4222-4234
41. Wolf J., Kapp U., Bohlen H., et al. Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells. Blood 87 8 (1996) 3418-3428
42. Kanzler H., Hansmann M.L., Kapp U., et al. Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient. Blood 87 8 (1996) 3429-3436
43. Schain F., Tryselius Y., Sjoberg J., et al. Evidence for a pathophysiological role of cysteinyl leukotrienes in classical Hodgkin lymphoma. Int J Cancer 123 10 (2008) 2285-2293
44. Schain F., Schain D., Mahshid Y., Liu C., et al. Differential expression of cysteinyl leukotriene receptor 1 and 15-lipoxygenase-1 in non-Hodgkin lymphomas. Clin Lymphoma Myeloma 8 6 (2008) 340-347
45. Nassar G.M., Morrow J.D., Roberts II L.J., Lakkis F.G., and Badr K.F. Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes. J Biol Chem 269 44 (1994) 27631-27634
46. Shirasaki H., Seki N., Fujita M., et al. Agonist- and T(H)2 cytokine-induced up-regulation of cysteinyl leukotriene receptor messenger RNA in human monocytes. Ann Allergy Asthma Immunol 99 4 (2007) 340-347
47. Kim E.Y., Battaile J.T., Patel A.C., et al. Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat Med 14 6 (2008) 633-640
48. Skinnider B.F., Kapp U., and Mak T.W. Interleukin 13: a growth factor in hodgkin lymphoma. Int Arch Allergy Immunol 126 4 (2001) 267-276
49. Holtzman M.J., Hansbrough J.R., Rosen G.D., and Turk J. Uptake, release and novel species-dependent oxygenation of arachidonic acid in human and animal airway epithelial cells. Biochim Biophys Acta 963 3 (1988) 401-413
50. Liminga M., Hornsten L., Sprecher H.W., and Oliw E.H. Arachidonate 15-lipoxygenase in human corneal epithelium and 12- and 15-lipoxygenases in bovine corneal epithelium: comparison with other bovine 12-lipoxygenases. Biochim Biophys Acta 1210 3 (1994) 288-296
51. Levy B.D., Romano M., Chapman H.A., Reilly J.J., Drazen J., and Serhan C.N. Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. J Clin Invest 92 3 (1993) 1572-1579
52. Spanbroek R., Hildner M., Kohler A., et al. IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression. Proc Natl Acad Sci USA 98 9 (2001) 5152-5157
53. Kroschwald P., Kroschwald A., Kuhn H., et al. Occurrence of the erythroid cell specific arachidonate 15-lipoxygenase in human reticulocytes. Biochem Biophys Res Commun 160 2 (1989) 954-960
54. Liagre B., Vergne P., Rigaud M., and Beneytout J.L. Arachidonate 15-lipoxygenase of reticulocyte-type in human rheumatoid arthritis type B synoviocytes and modulation of its activity by proinflammatory cytokines. J Rheumatol 26 5 (1999) 1044-1051
55. McGuire J., McGee J., Crittenden N., and Fitzpatrick F. Cell damage unmasks 15-lipoxygenase activity in human neutrophils. J Biol Chem 260 14 (1985) 8316-8319
56. Lee Y.W., Kuhn H., Kaiser S., Hennig B., Daugherty A., and Toborek M. Interleukin 4 induces transcription of the 15-lipoxygenase I gene in human endothelial cells. J Lipid Res 42 5 (2001) 783-791
57. Chen B., Tsui S., Boeglin W.E., Douglas R.S., Brash A.R., and Smith T.J. Interleukin-4 induces 15-lipoxygenase-1 expression in human orbital fibroblasts from patients with Graves disease. Evidence for anatomic site-selective actions of Th2 cytokines. J Biol Chem 281 27 (2006) 18296-18306
58. Oliw E.H., and Sprecher H. Metabolism of polyunsaturated fatty acids by an (n - 6)-lipoxygenase associated with human ejaculates. Biochim Biophys Acta 1002 3 (1989) 283-291