Basic mechanisms for recognition and transport of synaptic cargos

Molecular Brain

Volumn 2, Issue 1, 2009, Pages

  Schlager, Max A ^a   Hoogenraad, Casper C ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; AMPA RECEPTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; GLYCINE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN TYROSINE KINASE A; RAB PROTEIN; RNA; SYNAPTOBREVIN 2; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNTAXIN 1;

CALCIUM TRANSPORT; CYTOSKELETON; DENDRITE; ENDOSOME; ENZYME ACTIVATION; MICROTUBULE; MITOCHONDRION; MOTOR ACTIVITY; NERVE CELL; NERVE FIBER; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROCESSING; RECEPTOR BINDING; RECOGNITION; REVIEW; SIGNAL TRANSDUCTION; SPATIAL DISCRIMINATION; SYNAPSE; TRANSPORT VESICLE; ANIMAL; HUMAN; METABOLISM; SYNAPSE VESICLE; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; HUMANS; MICROTUBULES; MOTOR ACTIVITY; NEURONS; SIGNAL TRANSDUCTION; SYNAPTIC VESICLES;

EID: 69449091821     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-2-25     Document Type: Review

References (143)

1. The postsynaptic architecture of excitatory synapses: a more quantitative view. M Sheng CC Hoogenraad, Annu Rev Biochem 2007 76 823 847
2. Balancing structure and function at hippocampal dendritic spines. JN Bourne KM Harris, Annu Rev Neurosci 2008 31 47 67
3. GABA(A) receptor trafficking and its role in the dynamic modulation of neuronal inhibition. TC Jacob SJ Moss R Jurd, Nat Rev Neurosci 2008 9 331 343
4. Trafficking and synaptic anchoring of ionotropic inhibitory neurotransmitter receptors. M Kneussel S Loebrich, Biol Cell 2007 99 297 309
5. Building a synapse: lessons on synaptic specificity and presynaptic assembly from the nematode C. elegans. MA Margeta K Shen B Grill, Curr Opin Neurobiol 2008 18 69 76
6. Cellular and molecular mechanisms of presynaptic assembly. NE Ziv CC Garner, Nat Rev Neurosci 2004 5 385 399
7. PDZ domain proteins of synapses. E Kim M Sheng, Nat Rev Neurosci 2004 5 771 781
8. Molecular motors and mechanisms of directional transport in neurons. N Hirokawa R Takemura, Nat Rev Neurosci 2005 6 201 214
9. Axonal transport and the delivery of pre-synaptic components. AY Goldstein X Wang TL Schwarz, Curr Opin Neurobiol 2008 18 495 503
10. Motor-cargo interactions: the key to transport specificity. RL Karcher SW Deacon VI Gelfand, Trends Cell Biol 2002 12 21 27
11. Analysis of the kinesin superfamily: insights into structure and function. H Miki Y Okada N Hirokawa, Trends Cell Biol 2005 15 467 476
12. The molecular motor toolbox for intracellular transport. RD Vale, Cell 2003 112 467 480
13. Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics. N Hirokawa Y Noda, Physiol Rev 2008 88 1089 1118
14. Organelles and trafficking machinery for postsynaptic plasticity. MJ Kennedy MD Ehlers, Annu Rev Neurosci 2006 29 325 362
15. The cell biology of synaptic plasticity: AMPA receptor trafficking. JD Shepherd RL Huganir, Annu Rev Cell Dev Biol 2007 23 613 643
16. Neuroligins and neurexins link synaptic function to cognitive disease. TC Sudhof, Nature 2008 455 903 911
17. NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. CG Lau RS Zukin, Nat Rev Neurosci 2007 8 413 426
18. Molecular motors. M Schliwa G Woehlke, Nature 2003 422 759 765
19. Cargo transport: two motors are sometimes better than one. SP Gross M Vershinin GT Shubeita, Curr Biol 2007 17 R478 486
20. Bidirectional transport along microtubules. MA Welte, Curr Biol 2004 14 R525 537
21. Microtubule assembly, organization and dynamics in axons and dendrites. C Conde A Caceres, Nat Rev Neurosci 2009 10 319 332
22. Cytoskeletal dynamics and transport in growth cone motility and axon guidance. EW Dent FB Gertler, Neuron 2003 40 209 227
23. Molecular dynamics of postsynaptic receptors and scaffold proteins. M Renner CG Specht A Triller, Curr Opin Neurobiol 2008 18 532 540
24. The role of receptor diffusion in the organization of the postsynaptic membrane. D Choquet A Triller, Nat Rev Neurosci 2003 4 251 265
25. The role of the cytoskeleton during neuronal polarization. H Witte F Bradke, Curr Opin Neurobiol 2008 18 479 487
26. Axonal transport and neurodegenerative disease. E Chevalier-Larsen EL Holzbaur, Biochim Biophys Acta 2006 1762 1094 1108
27. The genetics of axonal transport and axonal transport disorders. JE Duncan LS Goldstein, PLoS Genet 2006 2 e124
28. Tracking the ends: a dynamic protein network controls the fate of microtubule tips. A Akhmanova MO Steinmetz, Nat Rev Mol Cell Biol 2008 9 309 322
29. Molecular mechanisms of dendritic spine morphogenesis. T Tada M Sheng, Curr Opin Neurobiol 2006 16 95 101
30. Molecular mechanisms of dendritic spine development and remodeling. IM Ethell EB Pasquale, Prog Neurobiol 2005 75 161 205
31. The dynein family at a glance. P Hook RB Vallee, J Cell Sci 2006 119 4369 4371
32. Of rings and levers: the dynein motor comes of age. MP Koonce M Samso, Trends Cell Biol 2004 14 612 619
33. 'Should I stay or should I go?': myosin V function in organelle trafficking. C Desnos S Huet F Darchen, Biol Cell 2007 99 411 423
34. Myosin-Va facilitates the accumulation of mRNA/protein complex in dendritic spines. A Yoshimura R Fujii Y Watanabe S Okabe K Fukui T Takumi, Curr Biol 2006 16 2345 2351
35. Myosin-dependent transport in neurons. PC Bridgman, J Neurobiol 2004 58 164 174
36. Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrite. PW Baas JS Deitch MM Black GA Banker, Proc Natl Acad Sci USA 1988 85 8335 8339
37. Microtubule plus-end tracking proteins in differentiated mammalian cells. J Jaworski CC Hoogenraad A Akhmanova, Int J Biochem Cell Biol 2008 40 619 637
38. Activity-dependent dynamic microtubule invasion of dendritic spines. X Hu C Viesselmann S Nam E Merriam EW Dent, J Neurosci 2008 28 13094 13105
39. Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. J Jaworski LC Kapitein SM Gouveia BR Dortland PS Wulf I Grigoriev P Camera SA Spangler P Di Stefano J Demmers H Krugers P Defilippi A Akhmanova CC Hoogenraad, Neuron 2009 61 85 100
40. Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function. GJ Bassell ST Warren, Neuron 2008 60 201 214
41. Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. Y Kanai N Dohmae N Hirokawa, Neuron 2004 43 513 525
42. Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein. SC Ling PS Fahrner WT Greenough VI Gelfand, Proc Natl Acad Sci USA 2004 101 17428 17433
43. The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules. L Davidovic XH Jaglin AM Lepagnol-Bestel S Tremblay M Simonneau B Bardoni EW Khandjian, Hum Mol Genet 2007 16 3047 3058
44. Local calcium release in dendritic spines required for long-term synaptic depression. M Miyata EA Finch L Khiroug K Hashimoto S Hayasaka SI Oda M Inouye Y Takagishi GJ Augustine M Kano, Neuron 2000 28 233 244
45. Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity. Z Wang JG Edwards N Riley DW Provance Jr R Karcher XD Li IG Davison M Ikebe JA Mercer JA Kauer MD Ehlers, Cell 2008 135 535 548
46. Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation. SS Correia S Bassani TC Brown MF Lise DS Backos A El-Husseini M Passafaro JA Esteban, Nat Neurosci 2008 11 457 466
47. Post-translational modifications regulate microtubule function. S Westermann K Weber, Nat Rev Mol Cell Biol 2003 4 938 947
48. The tubulin code. KJ Verhey J Gaertig, Cell Cycle 2007 6 2152 2160
49. Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function. K Ikegami RL Heier M Taruishi H Takagi M Mukai S Shimma S Taira K Hatanaka N Morone I Yao PK Campbell S Yuasa C Janke GR Macgregor M Setou, Proc Natl Acad Sci USA 2007 104 3213 3218
50. Tubulin tyrosination navigates the kinesin-1 motor domain to axons. Y Konishi M Setou, Nat Neurosci 2009 12 559 567
51. Biochemistry. Processive motor movement. DD Hackney, Science 2007 316 58 59
52. Kinesin motor mechanics: binding, stepping, tracking, gating, and limping. SM Block, Biophys J 2007 92 2986 2995
53. AAA+ Ring and linker swing mechanism in the dynein motor. AJ Roberts N Numata ML Walker YS Kato B Malkova T Kon R Ohkura F Arisaka PJ Knight K Sutoh SA Burgess, Cell 2009 136 485 495
54. Intramolecular strain coordinates kinesin stepping behavior along microtubules. A Yildiz M Tomishige A Gennerich RD Vale, Cell 2008 134 1030 1041
55. Kinesin's tail domain is an inhibitory regulator of the motor domain. DL Coy WO Hancock M Wagenbach J Howard, Nat Cell Biol 1999 1 288 292
56. The cargo-binding domain regulates structure and activity of myosin 5. K Thirumurugan T Sakamoto JA Hammer 3rd JR Sellers PJ Knight, Nature 2006 442 212 215
57. Dynactin increases the processivity of the cytoplasmic dynein motor. SJ King TA Schroer, Nat Cell Biol 2000 2 20 24
58. Dynactin enhances the processivity of kinesin-2. MA Berezuk TA Schroer, Traffic 2007 8 124 129
59. Dynactin. TA Schroer, Annu Rev Cell Dev Biol 2004 20 759 779
60. Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors. MJ Muller S Klumpp R Lipowsky, Proc Natl Acad Sci USA 2008 105 4609 4614
61. Coordination of opposite-polarity microtubule motors. SP Gross MA Welte SM Block EF Wieschaus, J Cell Biol 2002 156 715 724
62. Building complexity: an in vitro study of cytoplasmic dynein with in vivo implications. R Mallik D Petrov SA Lex SJ King SP Gross, Curr Biol 2005 15 2075 2085
63. Multiple-motor based transport and its regulation by Tau. M Vershinin BC Carter DS Razafsky SJ King SP Gross, Proc Natl Acad Sci USA 2007 104 87 92
64. Consequences of motor copy number on the intracellular transport of kinesin-1-driven lipid droplets. GT Shubeita SL Tran J Xu M Vershinin S Cermelli SL Cotton MA Welte SP Gross, Cell 2008 135 1098 1107
65. Dynamics of myo1c (myosin-ibeta) lipid binding and dissociation. N Tang T Lin EM Ostap, J Biol Chem 2002 277 42763 42768
66. Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor. DR Klopfenstein M Tomishige N Stuurman RD Vale, Cell 2002 109 347 358
67. Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins: a role for spectrin and acidic phospholipids. V Muresan MC Stankewich W Steffen JS Morrow EL Holzbaur BJ Schnapp, Mol Cell 2001 7 173 183
68. Intact lysosome transport and phagosome function despite kinectin deficiency. T Plitz K Pfeffer, Mol Cell Biol 2001 21 6044 6055
69. Kinectin, a major kinesin-binding protein on ER. I Toyoshima H Yu ER Steuer MP Sheetz, J Cell Biol 1992 118 1121 1131
70. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. A Kamal GB Stokin Z Yang CH Xia LS Goldstein, Neuron 2000 28 449 459
71. Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. O Lazarov GA Morfini EB Lee MH Farah A Szodorai SR DeBoer VE Koliatsos S Kins VM Lee PC Wong DL Price ST Brady SS Sisodia, J Neurosci 2005 25 2386 2395
72. Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1. AW Tai JZ Chuang C Bode U Wolfrum CH Sung, Cell 1999 97 877 887
73. Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor. H Yano FS Lee H Kong J Chuang J Arevalo P Perez C Sung MV Chao, J Neurosci 2001 21 RC125
74. Dynein motors transport activated Trks to promote survival of target-dependent neurons. HM Heerssen MF Pazyra RA Segal, Nat Neurosci 2004 7 596 604
75. Myosin V and Kinesin act as tethers to enhance each others' processivity. MY Ali H Lu CS Bookwalter DM Warshaw KM Trybus, Proc Natl Acad Sci USA 2008 105 4691 4696
76. Direct interaction of microtubule- and actin-based transport motors. JD Huang ST Brady BW Richards D Stenolen JH Resau NG Copeland NA Jenkins, Nature 1999 397 267 270
77. A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. LA Ligon M Tokito JM Finklestein FE Grossman EL Holzbaur, J Biol Chem 2004 279 19201 19208
78. Dynactin is required for bidirectional organelle transport. SW Deacon AS Serpinskaya PS Vaughan M Lopez Fanarraga I Vernos KT Vaughan VI Gelfand, J Cell Biol 2003 160 297 301
79. "JIP"ing along the axon: the complex roles of JIPs in axonal transport. SP Koushika, Bioessays 2008 30 10 14
80. Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. KJ Verhey D Meyer R Deehan J Blenis BJ Schnapp TA Rapoport B Margolis, J Cell Biol 2001 152 959 970
81. Control of a kinesin-cargo linkage mechanism by JNK pathway kinases. D Horiuchi CA Collins P Bhat RV Barkus A Diantonio WM Saxton, Curr Biol 2007 17 1313 1317
82. Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons. AD Pilling D Horiuchi CM Lively WM Saxton, Mol Biol Cell 2006 17 2057 2068
83. Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. EE Glater LJ Megeath RS Stowers TL Schwarz, J Cell Biol 2006 173 545 557
84. The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses. X Guo GT Macleod A Wellington F Hu S Panchumarthi M Schoenfield L Marin MP Charlton HL Atwood KE Zinsmaier, Neuron 2005 47 379 393
85. Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. RS Stowers LJ Megeath J Gorska-Andrzejak IA Meinertzhagen TL Schwarz, Neuron 2002 36 1063 1077
86. Postsynaptic scaffold proteins at non-synaptic sites. The role of postsynaptic scaffold proteins in motor-protein-receptor complexes. M Kneussel, EMBO Rep 2005 6 22 27
87. Motor protein receptors: moonlighting on other jobs. DR Klopfenstein RD Vale SL Rogers, Cell 2000 103 537 540
88. Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. M Setou DH Seog Y Tanaka Y Kanai Y Takei M Kawagishi N Hirokawa, Nature 2002 417 83 87
89. Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. M Setou T Nakagawa DH Seog N Hirokawa, Science 2000 288 1796 1802
90. KIF17 dynamics and regulation of NR2B trafficking in hippocampal neurons. L Guillaud M Setou N Hirokawa, J Neurosci 2003 23 131 140
91. Association of the kinesin motor KIF1A with the multimodular protein liprin-alpha. H Shin M Wyszynski KH Huh JG Valtschanoff JR Lee J Ko M Streuli RJ Weinberg M Sheng E Kim, J Biol Chem 2003 278 11393 11401
92. Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. CC Hoogenraad P Wulf N Schiefermeier T Stepanova N Galjart JV Small F Grosveld CI de Zeeuw A Akhmanova, EMBO J 2003 22 6004 6015
93. Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein. S Naisbitt J Valtschanoff DW Allison C Sala E Kim AM Craig RJ Weinberg M Sheng, J Neurosci 2000 20 4524 4534
94. Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins. H Mok H Shin S Kim JR Lee J Yoon E Kim, J Neurosci 2002 22 5253 5258
95. mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression. N Sans PY Wang Q Du RS Petralia YX Wang S Nakka JB Blumer IG Macara RJ Wenthold, Nat Cell Biol 2005 7 1179 1190
96. Rab proteins, connecting transport and vesicle fusion. I Jordens M Marsman C Kuijl J Neefjes, Traffic 2005 6 1070 1077
97. Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B. S Hoepfner F Severin A Cabezas B Habermann A Runge D Gillooly H Stenmark M Zerial, Cell 2005 121 437 450
98. Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease. A Pal F Severin B Lommer A Shevchenko M Zerial, J Cell Biol 2006 172 605 618
99. Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin. T Imamura J Huang I Usui H Satoh J Bever JM Olefsky, Mol Cell Biol 2003 23 4892 4900
100. The small GTPase Rab4A interacts with the central region of cytoplasmic dynein light intermediate chain-1. A Bielli PO Thornqvist AG Hendrick R Finn K Fitzgerald MW McCaffrey, Biochem Biophys Res Commun 2001 281 1141 1153
101. The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors. I Jordens M Fernandez-Borja M Marsman S Dusseljee L Janssen J Calafat H Janssen R Wubbolts J Neefjes, Curr Biol 2001 11 1680 1685
102. Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. G Cantalupo P Alifano V Roberti CB Bruni C Bucci, EMBO J 2001 20 683 693
103. Rab GTPases and myosin motors in organelle motility. MC Seabra E Coudrier, Traffic 2004 5 393 399
104. KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD. S Niwa Y Tanaka N Hirokawa, Nat Cell Biol 2008 10 1269 1279
105. A complete genetic analysis of neuronal Rab3 function. OM Schluter F Schmitz R Jahn C Rosenmund TC Sudhof, J Neurosci 2004 24 6629 6637
106. Rab6 regulates transport and targeting of exocytotic carriers. I Grigoriev D Splinter N Keijzer PS Wulf J Demmers T Ohtsuka M Modesti IV Maly F Grosveld CC Hoogenraad A Akhmanova, Dev Cell 2007 13 305 314
107. Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. T Matanis A Akhmanova P Wulf E Del Nery T Weide T Stepanova N Galjart F Grosveld B Goud CI De Zeeuw A Barnekow CC Hoogenraad, Nat Cell Biol 2002 4 986 992
108. Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. CC Hoogenraad A Akhmanova SA Howell BR Dortland CI De Zeeuw R Willemsen P Visser F Grosveld N Galjart, EMBO J 2001 20 4041 4054
109. Recycling endosomes supply AMPA receptors for LTP. M Park EC Penick JG Edwards JA Kauer MD Ehlers, Science 2004 305 1972 1975
110. UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly. H Toda H Mochizuki R Flores 3rd R Josowitz TB Krasieva VJ Lamorte E Suzuki JG Gindhart K Furukubo-Tokunaga T Tomoda, Genes Dev 2008 22 3292 3307
111. Regulatory dissociation of Tctex-1 light chain from dynein complex is essential for the apical delivery of rhodopsin. TY Yeh D Peretti JZ Chuang E Rodriguez-Boulan CH Sung, Traffic 2006 7 1495 1502
112. 14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking. J Rong S Li G Sheng M Wu B Coblitz M Li H Fu XJ Li, J Biol Chem 2007 282 4748 4756
113. The kinesin-like motor protein KIF1C occurs in intact cells as a dimer and associates with proteins of the 14-3-3 family. C Dorner A Ullrich HU Haring R Lammers, J Biol Chem 1999 274 33654 33660
114. Activity-dependent regulation of dendritic growth and patterning. RO Wong A Ghosh, Nat Rev Neurosci 2002 3 803 812
115. Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recycling. CM Hales JP Vaerman JR Goldenring, J Biol Chem 2002 277 50415 50421
116. Myosin V: regulation by calcium, calmodulin, and the tail domain. DN Krementsov EB Krementsova KM Trybus, J Cell Biol 2004 164 877 886
117. Mitochondrial trafficking to synapses in cultured primary cortical neurons. DT Chang AS Honick IJ Reynolds, J Neurosci 2006 26 7035 7045
118. The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility. X Wang TL Schwarz, Cell 2009 136 163 174
119. Postsynaptic signaling and plasticity mechanisms. M Sheng MJ Kim, Science 2002 298 776 780
120. Integration of biochemical signalling in spines. MB Kennedy HC Beale HJ Carlisle LR Washburn, Nat Rev Neurosci 2005 6 423 434
121. Cell cycle regulation of myosin-V by calcium/calmodulin-dependent protein kinase II. RL Karcher JT Roland F Zappacosta MJ Huddleston RS Annan SA Carr VI Gelfand, Science 2001 293 1317 1320
122. Liprinalpha1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase distribution and dendrite development. CC Hoogenraad MI Feliu-Mojer SA Spangler AD Milstein AW Dunah AY Hung M Sheng, Dev Cell 2007 12 587 602
123. Liprin-alpha proteins: scaffold molecules for synapse maturation. SA Spangler CC Hoogenraad, Biochem Soc Trans 2007 35 1278 1282
124. Direct observation demonstrates that Liprin-alpha is required for trafficking of synaptic vesicles. KE Miller J DeProto N Kaufmann BN Patel A Duckworth D Van Vactor, Curr Biol 2005 15 684 689
125. Targeting Rab GTPases to distinct membrane compartments. S Pfeffer D Aivazian, Nat Rev Mol Cell Biol 2004 5 886 896
126. Neuronal polarity: from extracellular signals to intracellular mechanisms. N Arimura K Kaibuchi, Nat Rev Neurosci 2007 8 194 205
127. Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27. N Arimura T Kimura S Nakamuta S Taya Y Funahashi A Hattori A Shimada C Menager S Kawabata K Fujii A Iwamatsu RA Segal M Fukuda K Kaibuchi, Dev Cell 2009 16 675 686
128. A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. K Yamaguchi M Tanaka A Mizoguchi Y Hirata H Ishizaki K Kaneko J Miyoshi Y Takai, Proc Natl Acad Sci USA 2002 99 14536 14541
129. Towards an understanding of kinesin-1 dependent transport pathways through the study of protein-protein interactions. JG Gindhart, Brief Funct Genomic Proteomic 2006 5 74 86
130. Interaction of SAP97 with minus-end-directed actin motor myosin VI. Implications for AMPA receptor trafficking. H Wu JE Nash P Zamorano CC Garner, J Biol Chem 2002 277 30928 30934
131. Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes. JC Fuhrmann S Kins P Rostaing O El Far J Kirsch M Sheng A Triller H Betz M Kneussel, J Neurosci 2002 22 5393 5402
132. Synaptic activation modifies microtubules underlying transport of postsynaptic cargo. C Maas D Belgardt HK Lee FF Heisler C Lappe-Siefke MM Magiera J van Dijk TJ Hausrat C Janke M Kneussel, Proc Natl Acad Sci USA 2009 106 8731 8736
133. BDNF-mediated neurotransmission relies upon a myosin VI motor complex. H Yano I Ninan H Zhang TA Milner O Arancio MV Chao, Nat Neurosci 2006 9 1009 1018
134. Brain myosin V is a synaptic vesicle-associated motor protein: evidence for a Ca2+-dependent interaction with the synaptobrevin-synaptophysin complex. R Prekeris DM Terrian, J Cell Biol 1997 137 1589 1601
135. Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon. A Fejtova D Davydova F Bischof V Lazarevic WD Altrock S Romorini C Schone W Zuschratter MR Kreutz CC Garner NE Ziv ED Gundelfinger, J Cell Biol 2009 185 341 355
136. Syntabulin-kinesin-1 family member 5B-mediated axonal transport contributes to activity-dependent presynaptic assembly. Q Cai PY Pan ZH Sheng, J Neurosci 2007 27 7284 7296
137. The heavy chain of conventional kinesin interacts with the SNARE proteins SNAP25 and SNAP23. RJ Diefenbach E Diefenbach MW Douglas AL Cunningham, Biochemistry 2002 41 14906 14915 (Pubitemid 35470669)
138. APLIP1, a kinesin binding JIP-1/JNK scaffold protein, influences the axonal transport of both vesicles and mitochondria in Drosophila. D Horiuchi RV Barkus AD Pilling A Gassman WM Saxton, Curr Biol 2005 15 2137 2141
139. Syntabulin-mediated anterograde transport of mitochondria along neuronal processes. Q Cai C Gerwin ZH Sheng, J Cell Biol 2005 170 959 969
140. Drosophila Miro is required for both anterograde and retrograde axonal mitochondrial transport. GJ Russo K Louie A Wellington GT Macleod F Hu S Panchumarthi KE Zinsmaier, J Neurosci 2009 29 5443 5455
141. Regulation of AMPA receptor extrasynaptic insertion by 4.1N, phosphorylation and palmitoylation. DT Lin Y Makino K Sharma T Hayashi R Neve K Takamiya RL Huganir, Nat Neurosci 2009 12 879 887
142. Endocytic Trafficking and Recycling Maintain a Pool of Mobile Surface AMPA Receptors Required for Synaptic Potentiation. EM Petrini J Lu L Cognet B Lounis MD Ehlers D Choquet, Neuron 2009 63 92 105
143. Plasticity of polarization: changing dendrites into axons in neurons integrated in neuronal circuits. S Gomis-Ruth CJ Wierenga F Bradke, Curr Biol 2008 18 992 1000