Cytoskeletal dynamics and transport in growth cone motility and guidance

Neuron

Volumn 40, Issue 2, 2003, Pages 209-227

  Dent, Erik W ^a   Gertler, Frank B ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; F ACTIN; G ACTIN; PACLITAXEL; POLYMER; PROTEIN; VINBLASTINE;

CELL VACUOLE; CYTOSKELETON; DRUG MECHANISM; FILOPODIUM; LAMELLIPODIUM; MICROTUBULE; MICROTUBULE ASSEMBLY; MORPHOLOGY; NERVE CELL; NERVE CELL CULTURE; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; REVIEW; THIN FILAMENT;

EID: 0141953237     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(03)00633-0     Document Type: Review

References (231)

1. Abe T.K., Tanaka H., Iwanaga T., Odani S., Kuwano R. The presence of the 50-kDa subunit of dynactin complex in the nerve growth cone. Biochem. Biophys. Res. Commun. 233:1997;295-299.
2. Ahmad F.J., Echeverri C.J., Vallee R.B., Baas P.W. Cytoplasmic dynein and dynactin are required for the transport of microtubules into the axon. J. Cell Biol. 140:1998;391-401.
3. Ahmad F.J., Yu W., McNally F.J., Baas P.W. An essential role for katanin in severing microtubules in the neuron. J. Cell Biol. 145:1999;305-315.
4. Ahmad F.J., Hughey J., Wittmann T., Hyman A., Greaser M., Baas P.W. Motor proteins regulate force interactions between microtubules and microfilaments in the axon. Nat. Cell Biol. 2:2000;276-280.
5. Aizawa H., Wakatsuki S., Ishii A., Moriyama K., Sasaki Y., Ohashi K., Sekine-Aizawa Y., Sehara-Fujisawa A., Mizuno K., Goshima Y., Yahara I. Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse. Nat. Neurosci. 4:2001;367-373.
6. Aletta J.M., Greene L.A. Growth cone configuration and advance. a time-lapse study using video-enhanced differential interference contrast microscopy J. Neurosci. 8:1988;1425-1435.
7. Allen R.D. New observations on cell architecture and dynamics by video-enhanced contrast optical microscopy. Annu. Rev. Biophys. Biophys. Chem. 14:1985;265-290.
8. Arakawa Y., Bito H., Furuyashiki T., Tsuji T., Takemoto-Kimura S., Kimura K., Nozaki K., Hashimoto N., Narumiya S. Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons. J. Cell Biol. 161:2003;381-391.
9. Argiro V., Bunge M.B., Johnson M.I. Correlation between growth form and movement and their dependence on neuronal age. J. Neurosci. 4:1984;3051-3062.
10. Argiro V., Bunge M.B., Johnson M.I. A quantitative study of growth cone filopodial extension. J. Neurosci. Res. 13:1985;149-162.
11. Baas P.W. Microtubule transport in the axon. Int. Rev. Cytol. 212:2002;41-62.
12. Baas P.W., Black M.M. Individual microtubules in the axon consist of domains that differ in both composition and stability. J. Cell Biol. 111:1990;495-509.
13. Baas P.W., Black M.M., Banker G.A. Changes in microtubule polarity orientation during the development of hippocampal neurons in culture. J. Cell Biol. 109:1989;3085-3094.
14. Barra H.S., Arce C.A., Argarana C.E. Posttranslational tyrosination/detyrosination of tubulin. Mol. Neurobiol. 2:1988;133-153.
15. Bashaw G.J., Kidd T., Murray D., Pawson T., Goodman C.S. Repulsive axon guidance. Abelson and Enabled play opposing roles downstream of the roundabout receptor Cell. 101:2000;703-715.
16. Bassell G.J., Zhang H., Byrd A.L., Femino A.M., Singer R.H., Taneja K.L., Lifshitz L.M., Herman I.M., Kosik K.S. Sorting of beta-actin mRNA and protein to neurites and growth cones in culture. J. Neurosci. 18:1998;251-265.
17. Bear J.E., Svitkina T.M., Krause M., Schafer D.A., Loureiro J.J., Strasser G.A., Maly I.V., Chaga O.Y., Cooper J.A., Borisy G.G., Gertler F.B. Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility. Cell. 109:2002;509-521.
18. Benfenati F., Valtorta F., Chieregatti E., Greengard P. Interaction of free and synaptic vesicle-bound synapsin I with F-actin. Neuron. 8:1992;377-386.
19. Bentley D., O'Connor T.P. Cytoskeletal events in growth cone steering. Curr. Opin. Neurobiol. 4:1994;43-48.
20. Bentley D., Toroian-Raymond A. Disoriented pathfinding by pioneer neurone growth cones deprived of filopodia by cytochalasin treatment. Nature. 323:1986;712-715.
21. Berg J.S., Cheney R.E. Myosin-X is an unconventional myosin that undergoes intrafilopodial motility. Nat. Cell Biol. 4:2002;246-250.
22. Black M.M. Microtubule transport and assembly cooperate to generate the microtubule array of growing axons. Prog. Brain Res. 102:1994;61-77.
23. Black M.M., Slaughter T., Moshiach S., Obrocka M., Fischer I. Tau is enriched on dynamic microtubules in the distal region of growing axons. J. Neurosci. 16:1996;3601-3619.
24. Bode C.J., Gupta M.L., Suprenant K.A., Himes R.H. The two alpha-tubulin isotypes in budding yeast have opposing effects on microtubule dynamics in vitro. EMBO Rep. 4:2003;94-99.
25. Bonnet C., Boucher D., Lazereg S., Pedrotti B., Islam K., Denoulet P., Larcher J.C. Differential binding regulation of microtubule-associated proteins MAP1A, MAP1B, and MAP2 by tubulin polyglutamylation. J. Biol. Chem. 276:2001;12839-12848.
26. Boquet I., Boujemaa R., Carlier M.F., Preat T. Ciboulot regulates actin assembly during Drosophila brain metamorphosis. Cell. 102:2000;797-808.
27. Boucher D., Larcher J.C., Gros F., Denoulet P. Polyglutamylation of tubulin as a progressive regulator of in vitro interactions between the microtubule-associated protein Tau and tubulin. Biochemistry. 33:1994;12471-12477.
28. Bray D., Chapman K. Analysis of microspike movements on the neuronal growth cone. J. Neurosci. 5:1985;3204-3213.
29. Bray D., Thomas C., Shaw G. Growth cone formation in cultures of sensory neurons. Proc. Natl. Acad. Sci. USA. 75:1978;5226-5229.
30. Bridgman P.C., Dailey M.E. The organization of myosin and actin in rapid frozen nerve growth cones. J. Cell Biol. 108:1989;95-109.
31. Bridgman P.C., Dave S., Asnes C.F., Tullio A.N., Adelstein R.S. Myosin IIB is required for growth cone motility. J. Neurosci. 21:2001;6159-6169.
32. Brown A. Axonal transport of membranous and nonmembranous cargoes. a unified perspective J. Cell Biol. 160:2003;817-821.
33. Brown J., Bridgman P.C. Role of myosin II in axon outgrowth. J. Histochem. Cytochem. 51:2003;421-428. a.
34. Brown M.E., Bridgman P.C. Retrograde flow rate is increased in growth cones from myosin IIB knockout mice. J. Cell Sci. 116:2003;1087-1094. b.
35. Brown A., Li Y., Slaughter T., Black M.M. Composite microtubules of the axon. quantitative analysis of tyrosinated and acetylated tubulin along individual axonal microtubules J. Cell Sci. 104:1993;339-352.
36. Buck K.B., Zheng J.Q. Growth cone turning induced by direct local modification of microtubule dynamics. J. Neurosci. 22:2002;9358-9367.
37. Bunge M.B. Fine structure of nerve fibers and growth cones of isolated sympathetic neurons in culture. J. Cell Biol. 56:1973;713-735.
38. Byk T., Dobransky T., Cifuentes-Diaz C., Sobel A. Identification and molecular characterization of Unc-33-like phosphoprotein (Ulip), a putative mammalian homolog of the axonal guidance-associated unc-33 gene product. J. Neurosci. 16:1996;688-701.
39. Cajal S.R. À quelle époque apparaissent les expansions des cellules nerveuses de la moëlle épinière du poulet? Anatomomischer Anzeiger. 21-22:1890;609-639.
40. Carvalho P., Tirnauer J.S., Pellman D. Surfing on microtubule ends. Trends Cell Biol. 13:2003;229-237.
41. Cassimeris L., Spittle C. Regulation of microtubule-associated proteins. Int. Rev. Cytol. 210:2001;163-226.
42. Castelo L., Jay D.G. Radixin is involved in lamellipodial stability during nerve growth cone motility. Mol. Biol. Cell. 10:1999;1511-1520.
43. Challacombe J.F., Snow D.M., Letourneau P.C. Actin filament bundles are required for microtubule reorientation during growth cone turning to avoid an inhibitory guidance cue. J. Cell Sci. 109:1996;2031-2040.
44. Challacombe J.F., Snow D.M., Letourneau P.C. Dynamic microtubule ends are required for growth cone turning to avoid an inhibitory guidance cue. J. Neurosci. 17:1997;3085-3095.
45. Chien C.B., Rosenthal D.E., Harris W.A., Holt C.E. Navigational errors made by growth cones without filopodia in the embryonic Xenopus brain. Neuron. 11:1993;237-251.
46. Choo Q.L., Bray D. Two forms of neuronal actin. J. Neurochem. 31:1978;217-224.
47. Cohan C.S., Welnhofer E.A., Zhao L., Matsumura F., Yamashiro S. Role of the actin bundling protein fascin in growth cone morphogenesis. localization in filopodia and lamellipodia Cell Motil. Cytoskeleton. 48:2001;109-120.
48. Colavita A., Culotti J.G. Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans. Dev. Biol. 194:1998;72-85.
49. Contin M.A., Arce C.A. Tubulin carboxypeptidase/microtubules association can be detected in the distal region of neural processes. Neurochem. Res. 25:2000;27-36.
50. da Silva J.S., Dotti C.G. Breaking the neuronal sphere. regulation of the actin cytoskeleton in neuritogenesis Nat. Rev. Neurosci. 3:2002;694-704.
51. Dailey M.E., Bridgman P.C. Structure and organization of membrane organelles along distal microtubule segments in growth cones. J. Neurosci. Res. 30:1991;242-258.
52. Danuser G., Waterman-Storer C.M. Quantitative fluorescent speckle microscopy. where it came from and where it is going J. Microsc. 211:2003;191-207.
53. Davare M.A., Dong F., Rubin C.S., Hell J.W. The A-kinase anchor protein MAP2B and cAMP-dependent protein kinase are associated with class C L-type calcium channels in neurons. J. Biol. Chem. 274:1999;30280-30287.
54. Dent E.W., Kalil K. Axon branching requires interactions between dynamic microtubules and actin filaments. J. Neurosci. 21:2001;9757-9769.
55. Dent E.W., Meiri K.F. GAP-43 phosphorylation is dynamically regulated in individual growth cones. J. Neurobiol. 23:1992;1037-1053.
56. Dent E.W., Meiri K.F. Distribution of phosphorylated GAP-43 (neuromodulin) in growth cones directly reflects growth cone behavior. J. Neurobiol. 35:1998;287-299.
57. Dent E.W., Callaway J.L., Szebenyi G., Baas P.W., Kalil K. Reorganization and movement of microtubules in axonal growth cones and developing interstitial branches. J. Neurosci. 19:1999;8894-8908.
58. Derry W.B., Wilson L., Khan I.A., Luduena R.F., Jordan M.A. Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes. Biochemistry. 36:1997;3554-3562.
59. Di Paolo G., Antonsson B., Kassel D., Riederer B.M., Grenningloh G. Phosphorylation regulates the microtubule-destabilizing activity of stathmin and its interaction with tubulin. FEBS Lett. 416:1997;149-152. a.
60. Di Paolo G., Lutjens R., Osen-Sand A., Sobel A., Catsicas S., Grenningloh G. Differential distribution of stathmin and SCG10 in developing neurons in culture. J. Neurosci. Res. 50:1997;1000-1009. b.
61. Dickson B.J. Molecular mechanisms of axon guidance. Science. 298:2002;1959-1964.
62. Diefenbach T.J., Latham V.M., Yimlamai D., Liu C.A., Herman I.M., Jay D.G. Myosin 1c and myosin IIB serve opposing roles in lamellipodial dynamics of the neuronal growth cone. J. Cell Biol. 158:2002;1207-1217.
63. Du Y., Weed S.A., Xiong W.C., Marshall T.D., Parsons J.T. Identification of a novel cortactin SH3 domain-binding protein and its localization to growth cones of cultured neurons. Mol. Cell. Biol. 18:1998;5838-5851.
64. Endo M., Ohashi K., Sasaki Y., Goshima Y., Niwa R., Uemura T., Mizuno K. Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin. J. Neurosci. 23:2003;2527-2537.
65. Evans L.L., Hammer J., Bridgman P.C. Subcellular localization of myosin V in nerve growth cones and outgrowth from dilute-lethal neurons. J. Cell Sci. 110:1997;439-449.
66. Eyer J., Peterson A. Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-beta-galactosidase fusion protein. Neuron. 12:1994;389-405.
67. Faivre-Sarrailh C., Lena J.Y., Had L., Vignes M., Lindberg U. Location of profilin at presynaptic sites in the cerebellar cortex; implication for the regulation of the actin-polymerization state during axonal elongation and synaptogenesis. J. Neurocytol. 22:1993;1060-1072.
68. Feng Y., Walsh C.A. Protein-protein interactions, cytoskeletal regulation and neuronal migration. Nat. Rev. Neurosci. 2:2001;408-416.
69. Ferhat L., Cook C., Chauviere M., Harper M., Kress M., Lyons G.E., Baas P.W. Expression of the mitotic motor protein Eg5 in postmitotic neurons. implications for neuronal development J. Neurosci. 18:1998;7822-7835.
70. Ferreira A., Kao H.T., Feng J., Rapoport M., Greengard P. Synapsin III. developmental expression, subcellular localization, and role in axon formation J. Neurosci. 20:2000;3736-3744.
71. Fischer I., Shea T.B., Sapirstein V.S., Kosik K.S. Expression and distribution of microtubule-associated protein 2 (MAP2) in neuroblastoma and primary neuronal cells. Brain Res. 390:1986;99-109.
72. Fletcher T.L., Cameron P., De Camilli P., Banker G. The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture. J. Neurosci. 11:1991;1617-1626.
73. Forscher P., Smith S.J. Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone. J. Cell Biol. 107:1988;1505-1516.
74. Fowler V.M. Capping actin filament growth. tropomodulin in muscle and nonmuscle cells Soc. Gen. Physiol. Ser. 52:1997;79-89.
75. Francis F., Koulakoff A., Boucher D., Chafey P., Schaar B., Vinet M.C., Friocourt G., McDonnell N., Reiner O., Kahn A.et al. Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons. Neuron. 23:1999;247-256.
76. Frey D., Laux T., Xu L., Schneider C., Caroni P. Shared and unique roles of CAP23 and GAP43 in actin regulation, neurite outgrowth, and anatomical plasticity. J. Cell Biol. 149:2000;1443-1454.
77. Fritsche J., Reber B.F., Schindelholz B., Bandtlow C.E. Differential cytoskeletal changes during growth cone collapse in response to hSema III and thrombin. Mol. Cell. Neurosci. 14:1999;398-418.
78. Fukata M., Watanabe T., Noritake J., Nakagawa M., Yamaga M., Kuroda S., Matsuura Y., Iwamatsu A., Perez F., Kaibuchi K. Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell. 109:2002;873-885. a.
79. Fukata Y., Itoh T.J., Kimura T., Menager C., Nishimura T., Shiromizu T., Watanabe H., Inagaki N., Iwamatsu A., Hotani H., Kaibuchi K. CRMP-2 binds to tubulin heterodimers to promote microtubule assembly. Nat. Cell Biol. 4:2002;583-591. b.
80. Galjart N., Perez F. A plus-end raft to control microtubule dynamics and function. Curr. Opin. Cell Biol. 15:2003;48-53.
81. Gallo G., Letourneau P.C. Different contributions of microtubule dynamics and transport to the growth of axons and collateral sprouts. J. Neurosci. 19:1999;3860-3873.
82. Gallo G., Yee H.F. Jr., Letourneau P.C. Actin turnover is required to prevent axon retraction driven by endogenous actomyosin contractility. J. Cell Biol. 158:2002;1219-1228.
83. Gitai Z., Yu T.W., Lundquist E.A., Tessier-Lavigne M., Bargmann C.I. The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM. Neuron. 37:2003;53-65.
84. Godement P., Wang L.C., Mason C.A. Retinal axon divergence in the optic chiasm. dynamics of growth cone behavior at the midline J. Neurosci. 14:1994;7024-7039.
85. Goldberg D.J., Burmeister D.W. Stages in axon formation. observations of growth of Aplysia axons in culture using video-enhanced contrast-differential interference contrast microscopy J. Cell Biol. 103:1986;1921-1931.
86. Goldberg D.J., Foley M.S., Tang D., Grabham P.W. Recruitment of the Arp2/3 complex and mena for the stimulation of actin polymerization in growth cones by nerve growth factor. J. Neurosci. Res. 60:2000;458-467.
87. Gonzalez-Billault C., Avila J., Caceres A. Evidence for the role of MAP1B in axon formation. Mol. Biol. Cell. 12:2001;2087-2098.
88. Gordon-Weeks P.R. Evidence for microtubule capture by filopodial actin filaments in growth cones. Neuroreport. 2:1991;573-576.
89. Gordon-Weeks P.R. Neuronal Growth Cones, Volume 37. 2000;Cambridge University Press, Cambridge, UK.
90. Gordon-Weeks P.R., Fischer I. MAP1B expression and microtubule stability in growing and regenerating axons. Microsc. Res. Tech. 48:2000;63-74.
91. Gundersen G.G. Evolutionary conservation of microtubule-capture mechanisms. Nat. Rev. Mol. Cell Biol. 3:2002;296-304.
92. Gungabissoon R.A., Bamburg J.R. Regulation of growth cone actin dynamics by ADF/Cofilin. J. Histochem. Cytochem. 51:2003;411-420.
93. Gunning P., Hardeman E., Jeffrey P., Weinberger R. Creating intracellular structural domains. spatial segregation of actin and tropomyosin isoforms in neurons Bioessays. 20:1998;892-900.
94. Gurland G., Gundersen G.G. Stable, detyrosinated microtubules function to localize vimentin intermediate filaments in fibroblasts. J. Cell Biol. 131:1995;1275-1290.
95. Halloran M.C., Kalil K. Dynamic behaviors of growth cones extending in the corpus callosum of living cortical brain slices observed with video microscopy. J. Neurosci. 14:1994;2161-2177.
96. Harris W.A., Holt C.E., Bonhoeffer F. Retinal axons with and without their somata, growing to and arborizing in the tectum of Xenopus embryos. a time-lapse video study of single fibres in vivo Development. 101:1987;123-133.
97. Harrison R.G. Observations on the living developing nerve fiber. Anat. Rec. 1:1907;116-118.
98. Harrison R.G. The outgrowth of the nerve fiber as a mode of protoplasmic movement. J. Exp. Zool. 9:1910;787-848.
99. He Q., Dent E.W., Meiri K.F. Modulation of actin filament behavior by GAP-43 (neuromodulin) is dependent on the phosphorylation status of serine 41, the protein kinase C site. J. Neurosci. 17:1997;3515-3524.
100. Ho H.Y., Rohatgi R., Ma L., Kirschner M.W. CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family. Proc. Natl. Acad. Sci. USA. 98:2001;11306-11311.
101. Holy T.E., Leibler S. Dynamic instability of microtubules as an efficient way to search in space. Proc. Natl. Acad. Sci. USA. 91:1994;5682-5685.
102. Homma N., Takei Y., Tanaka Y., Nakata T., Terada S., Kikkawa M., Noda Y., Hirokawa N. Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension. Cell. 114:2003;229-239.
103. Huber A.B., Kolodkin A.L., Ginty D.D., Cloutier J.F. Signaling at the growth cone. ligand-receptor complexes and the control of axon growth and guidance Annu. Rev. Neurosci. 26:2003;509-563.
104. Hughes A. The growth of embryonic neurites. A study on cultures of chick neural tissues. J. Anat. 87:1953;150-162.
105. Kabir N., Schaefer A.W., Nakhost A., Sossin W.S., Forscher P. Protein kinase C activation promotes microtubule advance in neuronal growth cones by increasing average microtubule growth lifetimes. J. Cell Biol. 152:2001;1033-1044.
106. Kalil K. Growth cone behaviors during axon guidance in the developing cerebral cortex. Prog. Brain Res. 108:1996;31-40.
107. Kalil K., Szebenyi G., Dent E.W. Common mechanisms underlying growth cone guidance and axon branching. J. Neurobiol. 44:2000;145-158.
108. Katoh K., Hammar K., Smith P.J., Oldenbourg R. Arrangement of radial actin bundles in the growth cone of Aplysia bag cell neurons shows the immediate past history of filopodial behavior. Proc. Natl. Acad. Sci. USA. 96:1999;7928-7931.
109. Katsetos C.D., Herman M.M., Mork S.J. Class III beta-tubulin in human development and cancer. Cell Motil. Cytoskeleton. 55:2003;77-96.
110. Kaufmann N., Wills Z.P., Van Vactor D. Drosophila Rac1 controls motor axon guidance. Development. 125:1998;453-461.
111. Khan I.A., Luduena R.F. Different effects of vinblastine on the polymerization of isotypically purified tubulins from bovine brain. Invest. New Drugs. 21:2003;3-13.
112. Khawaja S., Gundersen G.G., Bulinski J.C. Enhanced stability of microtubules enriched in detyrosinated tubulin is not a direct function of detyrosination level. J. Cell Biol. 106:1988;141-149.
113. Kim Y.S., Furman S., Sink H., VanBerkum M.F. Calmodulin and profilin coregulate axon outgrowth in Drosophila. J. Neurobiol. 47:2001;26-38.
114. Kim Y.S., Fritz J.L., Seneviratne A.K., VanBerkum M.F. Constitutively active myosin light chain kinase alters axon guidance decisions in Drosophila embryos. Dev. Biol. 249:2002;367-381.
115. Kreitzer G., Liao G., Gundersen G.G. Detyrosination of tubulin regulates the interaction of intermediate filaments with microtubules in vivo via a kinesin-dependent mechanism. Mol. Biol. Cell. 10:1999;1105-1118.
116. Krylova O., Messenger M.J., Salinas P.C. Dishevelled-1 regulates microtubule stability. a new function mediated by glycogen synthase kinase-3beta J. Cell Biol. 151:2000;83-94.
117. Krylyshkina O., Anderson K.I., Kaverina I., Upmann I., Manstein D.J., Small J.V., Toomre D.K. Nanometer targeting of microtubules to focal adhesions. J. Cell Biol. 161:2003;853-859.
118. Lafanechere L., Job D. The third tubulin pool. Neurochem. Res. 25:2000;11-18.
119. Lafont F., Rouget M., Rousselet A., Valenza C., Prochiantz A. Specific responses of axons and dendrites to cytoskeleton perturbations. an in vitro study J. Cell Sci. 104:1993;433-443.
120. Lambert de Rouvroit C., Goffinet A.M. Neuronal migration. Mech. Dev. 105:2001;47-56.
121. Lanier L.M., Gates M.A., Witke W., Menzies A.S., Wehman A.M., Macklis J.D., Kwiatkowski D., Soriano P., Gertler F.B. Mena is required for neurulation and commissure formation. Neuron. 22:1999;313-325.
122. Larcher J.C., Boucher D., Lazereg S., Gros F., Denoulet P. Interaction of kinesin motor domains with alpha- and beta-tubulin subunits at a tau-independent binding site. Regulation by polyglutamylation. J. Biol. Chem. 271:1996;22117-22124.
123. Lee S., Kolodziej P.A. Short Stop provides an essential link between F-actin and microtubules during axon extension. Development. 129:2002;1195-1204.
124. Lee H., Van Vactor D. Neurons take shape. Curr. Biol. 13:2003;R152-R161.
125. Letourneau P.C. Differences in the organization of actin in the growth cones compared with the neurites of cultured neurons from chick embryos. J. Cell Biol. 97:1983;963-973.
126. Letourneau P.C., Shattuck T.A. Distribution and possible interactions of actin-associated proteins and cell adhesion molecules of nerve growth cones. Development. 105:1989;505-519.
127. Lewis A.K., Bridgman P.C. Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarity. J. Cell Biol. 119:1992;1219-1243.
128. Lewis A.K., Bridgman P.C. Mammalian myosin I alpha is concentrated near the plasma membrane in nerve growth cones. Cell Motil. Cytoskeleton. 33:1996;130-150.
129. Li Y., Black M.M. Microtubule assembly and turnover in growing axons. J. Neurosci. 16:1996;531-544.
130. Liao G., Gundersen G.G. Kinesin is a candidate for cross-bridging microtubules and intermediate filaments. Selective binding of kinesin to detyrosinated tubulin and vimentin. J. Biol. Chem. 273:1998;9797-9803.
131. Lin C.H., Forscher P. Cytoskeletal remodeling during growth cone-target interactions. J. Cell Biol. 121:1993;1369-1383.
132. Lin C.H., Forscher P. Growth cone advance is inversely proportional to retrograde F-actin flow. Neuron. 14:1995;763-771.
133. Lin W., Szaro B.G. Neurofilaments help maintain normal morphologies and support elongation of neurites in Xenopus laevis cultured embryonic spinal cord neurons. J. Neurosci. 15:1995;8331-8344.
134. Lin C.H., Thompson C.A., Forscher P. Cytoskeletal reorganization underlying growth cone motility. Curr. Opin. Neurobiol. 4:1994;640-647.
135. Lin C.H., Espreafico E.M., Mooseker M.S., Forscher P. Myosin drives retrograde F-actin flow in neuronal growth cones. Neuron. 16:1996;769-782.
136. Lu M., Witke W., Kwiatkowski D.J., Kosik K.S. Delayed retraction of filopodia in gelsolin null mice. J. Cell Biol. 138:1997;1279-1287.
137. Luduena R.F. Multiple forms of tubulin. different gene products and covalent modifications Int. Rev. Cytol. 178:1998;207-275.
138. Lundquist E.A., Herman R.K., Shaw J.E., Bargmann C.I. UNC-115, a conserved protein with predicted LIM and actin-binding domains, mediates axon guidance in C. elegans. Neuron. 21:1998;385-392.
139. Luo L. Rho GTPases in neuronal morphogenesis. Nat. Rev. Neurosci. 1:2000;173-180.
140. Luo L. Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity. Annu. Rev. Cell Dev. Biol. 18:2002;601-635.
141. Mack T.G., Koester M.P., Pollerberg G.E. The microtubule-associated protein MAP1B is involved in local stabilization of turning growth cones. Mol. Cell. Neurosci. 15:2000;51-65.
142. MacRae T.H. Tubulin post-translational modifications - enzymes and their mechanisms of action. Eur. J. Biochem. 244:1997;265-278.
143. Mallavarapu A., Mitchison T. Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retraction. J. Cell Biol. 146:1999;1097-1106.
144. Marsh L., Letourneau P.C. Growth of neurites without filopodial or lamellipodial activity in the presence of cytochalasin B. J. Cell Biol. 99:1984;2041-2047.
145. Matus A. Microtubule-associated proteins and neuronal morphogenesis. J. Cell Sci. Suppl. 15:1991;61-67.
146. Meberg P.J., Bamburg J.R. Increase in neurite outgrowth mediated by overexpression of actin depolymerizing factor. J. Neurosci. 20:2000;2459-2469.
147. Meyer G., Feldman E.L. Signaling mechanisms that regulate actin-based motility processes in the nervous system. J. Neurochem. 83:2002;490-503.
148. Mitchison T., Kirschner M. Dynamic instability of microtubule growth. Nature. 312:1984;237-242.
149. Moresco E.M.Y., Koleske A.J. Regulation of neuronal morphogenesis and synaptic function by Abl family kinases. Curr. Opin. Neurobiol. 13:2003;1-10.
150. Morfini G., DiTella M.C., Feiguin F., Carri N., Caceres A. Neurotrophin-3 enhances neurite outgrowth in cultured hippocampal pyramidal neurons. J. Neurosci. Res. 39:1994;219-232.
151. Morfini G., Quiroga S., Rosa A., Kosik K., Caceres A. Suppression of KIF2 in PC12 cells alters the distribution of a growth cone nonsynaptic membrane receptor and inhibits neurite extension. J. Cell Biol. 138:1997;657-669.
152. Morfini G., Szebenyi G., Richards B., Brady S.T. Regulation of kinesin. implications for neuronal development Dev. Neurosci. 23:2001;364-376.
153. Mori N., Morii H. SCG10-related neuronal growth-associated proteins in neural development, plasticity, degeneration, and aging. J. Neurosci. Res. 70:2002;264-273.
154. Morrison E.E., Moncur P.M., Askham J.M. EB1 identifies sites of microtubule polymerisation during neurite development. Brain Res. Mol. Brain Res. 98:2002;145-152.
155. Mueller B.K. Growth cone guidance. first steps towards a deeper understanding Annu. Rev. Neurosci. 22:1999;351-388.
156. Nakai J. Dissociated dorsal root ganglia in tissue culture. Am. J. Anat. 99:1956;81-129.
157. Nakamura T., Takeuchi K., Muraoka S., Takezoe H., Takahashi N., Mori N. A neurally enriched coronin-like protein, ClipinC, is a novel candidate for an actin cytoskeleton-cortical membrane-linking protein. J. Biol. Chem. 274:1999;13322-13327.
158. Ng J., Nardine T., Harms M., Tzu J., Goldstein A., Sun Y., Dietzl G., Dickson B.J., Luo L. Rac GTPases control axon growth, guidance and branching. Nature. 416:2002;442-447.
159. Niethammer M., Smith D.S., Ayala R., Peng J., Ko J., Lee M.S., Morabito M., Tsai L.H. NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron. 28:2000;697-711.
160. Nogales E., Whittaker M., Milligan R.A., Downing K.H. High-resolution model of the microtubule. Cell. 96:1999;79-88.
161. Okabe S., Hirokawa N. Actin dynamics in growth cones. J. Neurosci. 11:1991;1918-1929.
162. O'Leary D.D., Bicknese A.R., De Carlos J.A., Heffner C.D., Koester S.E., Kutka L.J., Terashima T. Target selection by cortical axons. alternative mechanisms to establish axonal connections in the developing brain Cold Spring Harb. Symp. Quant. Biol. 55:1990;453-468.
163. Ozer R.S., Halpain S. Phosphorylation-dependent localization of microtubule-associated protein MAP2c to the actin cytoskeleton. Mol. Biol. Cell. 11:2000;3573-3587.
164. Paglini G., Kunda P., Quiroga S., Kosik K., Caceres A. Suppression of radixin and moesin alters growth cone morphology, motility, and process formation in primary cultured neurons. J. Cell Biol. 143:1998;443-455.
165. Panda D., Miller H.P., Banerjee A., Luduena R.F., Wilson L. Microtubule dynamics in vitro are regulated by the tubulin isotype composition. Proc. Natl. Acad. Sci. USA. 91:1994;11358-11362.
166. Paturle-Lafanechere L., Manier M., Trigault N., Pirollet F., Mazarguil H., Job D. Accumulation of delta 2-tubulin, a major tubulin variant that cannot be tyrosinated, in neuronal tissues and in stable microtubule assemblies. J. Cell Sci. 107:1994;1529-1543.
167. Plantier M., Fattoum A., Menn B., Ben-Ari Y., Der Terrossian E., Represa A. Acidic calponin immunoreactivity in postnatal rat brain and cultures. subcellular localization in growth cones, under the plasma membrane and along actin and glial filaments Eur. J. Neurosci. 11:1999;2801-2812.
168. Pollard T.D., Borisy G.G. Cellular motility driven by assembly and disassembly of actin filaments. Cell. 112:2003;453-465.
169. Ponti A., Vallotton P., Salmon W.C., Waterman-Storer C.M., Danuser G. Computational analysis of f-actin turnover in cortical actin meshworks using fluorescent speckle microscopy. Biophys. J. 84:2003;3336-3352.
170. Quinn C.C., Chen E., Kinjo T.G., Kelly G., Bell A.W., Elliott R.C., McPherson P.S., Hockfield S. TUC-4b, a novel TUC family variant, regulates neurite outgrowth and associates with vesicles in the growth cone. J. Neurosci. 23:2003;2815-2823.
171. Ranganathan S., Benetatos C.A., Colarusso P.J., Dexter D.W., Hudes G.R. Altered beta-tubulin isotype expression in paclitaxel-resistant human prostate carcinoma cells. Br. J. Cancer. 77:1998;562-566.
172. Rochlin M.W., Itoh K., Adelstein R.S., Bridgman P.C. Localization of myosin II A and B isoforms in cultured neurons. J. Cell Sci. 108:1995;3661-3670.
173. Rochlin M.W., Wickline K.M., Bridgman P.C. Microtubule stability decreases axon elongation but not axoplasm production. J. Neurosci. 16:1996;3236-3246.
174. Rochlin M.W., Dailey M.E., Bridgman P.C. Polymerizing microtubules activate site-directed F-actin assembly in nerve growth cones. Mol. Biol. Cell. 10:1999;2309-2327.
175. Rodriguez O.C., Schaefer A.W., Mandato C.A., Forscher P., Bement W.M., Waterman-Storer C.M. Conserved microtubule-actin interactions in cell movement and morphogenesis. Nat. Cell Biol. 5:2003;599-609.
176. Roos J., Hummel T., Ng N., Klambt C., Davis G.W. Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth. Neuron. 26:2000;371-382.
177. Roth L.W., Bormann P., Bonnet A., Reinhard E. beta-thymosin is required for axonal tract formation in developing zebrafish brain. Development. 126:1999;1365-1374.
178. Rothenberg M.E., Rogers S.L., Vale R.D., Jan L.Y., Jan Y.-N. Drosophila Pod-1 crosslinks both actin and microtubules and controls targeting of axons. Neuron. 39:2003;779-791.
179. Sabry J.H., O'Connor T.P., Evans L., Toroian-Raymond A., Kirschner M., Bentley D. Microtubule behavior during guidance of pioneer neuron growth cones in situ. J. Cell Biol. 115:1991;381-395.
180. Sammak P.J., Borisy G.G. Direct observation of microtubule dynamics in living cells. Nature. 332:1988;724-726.
181. Sanchez-Martin C., Ledesma D., Dotti C.G., Avila J. Microtubule-associated protein-2 located in growth regions of rat hippocampal neurons is highly phosphorylated at its proline-rich region. Neuroscience. 101:2000;885-893.
182. Sasaki S., Shionoya A., Ishida M., Gambello M.J., Yingling J., Wynshaw-Boris A., Hirotsune S. A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron. 28:2000;681-696.
183. Schaefer A.W., Kabir N., Forscher P. Filopodia and actin arcs guide the assembly and transport of two populations of microtubules with unique dynamic parameters in neuronal growth cones. J. Cell Biol. 158:2002;139-152.
184. Schevzov G., Gunning P., Jeffrey P.L., Temm-Grove C., Helfman D.M., Lin J.J., Weinberger R.P. Tropomyosin localization reveals distinct populations of microfilaments in neurites and growth cones. Mol. Cell. Neurosci. 8:1997;439-454.
185. Schnapp B.J., Reese T.S. Cytoplasmic structure in rapid-frozen axons. J. Cell Biol. 94:1982;667-669.
186. Schulze E., Kirschner M. New features of microtubule behaviour observed in vivo. Nature. 334:1988;356-359.
187. Schuyler S.C., Pellman D. Microtubule "plus-end-tracking proteins" the end is just the beginning Cell. 105:2001;421-424.
188. Schwarz P.M., Liggins J.R., Luduena R.F. Beta-tubulin isotypes purified from bovine brain have different relative stabilities. Biochemistry. 37:1998;4687-4692.
189. Shaw G., Osborn M., Weber K. Arrangement of neurofilaments, microtubules and microfilament-associated proteins in cultured dorsal root ganglia cells. Eur. J. Cell Biol. 24:1981;20-27.
190. Shaw G., Banker G.A., Weber K. An immunofluorescence study of neurofilament protein expression by developing hippocampal neurons in tissue culture. Eur. J. Cell Biol. 39:1985;205-216.
191. Sheetz M.P., Steuer E.R., Schroer T.A. The mechanism and regulation of fast axonal transport. Trends Neurosci. 12:1989;474-478.
192. Slaughter T., Wang J., Black M.M. Microtubule transport from the cell body into the axons of growing neurons. J. Neurosci. 17:1997;5807-5819.
193. Smith S.J. Neuronal cytomechanics. the actin-based motility of growth cones Science. 242:1988;708-715.
194. Sobue K. Actin-based cytoskeleton in growth cone activity. Neurosci. Res. 18:1993;91-102.
195. Sobue K., Kanda K. Alpha-actinins, calspectin (brain spectrin or fodrin), and actin participate in adhesion and movement of growth cones. Neuron. 3:1989;311-319.
196. Song H., Poo M. The cell biology of neuronal navigation. Nat. Cell Biol. 3:2001;E81-E88.
197. Speidel C.C. Studies of living nerves II. Activities of ameboid growth cones, sheath cells, and myelin segments, as revealed by prolonged observation of individual nerve fibers in frog tadpoles. Am. J. Anat. 52:1933;1-79.
198. Steketee M.B., Tosney K.W. Three functionally distinct adhesions in filopodia. shaft adhesions control lamellar extension J. Neurosci. 22:2002;8071-8083.
199. Stepanova T., Slemmer J., Hoogenraad C.C., Lansbergen G., Dortland B., De Zeeuw C.I., Grosveld F., van Cappellen G., Akhmanova A., Galjart N. Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). J. Neurosci. 23:2003;2655-2664.
200. Suter D.M., Forscher P. Substrate-cytoskeletal coupling as a mechanism for the regulation of growth cone motility and guidance. J. Neurobiol. 44:2000;97-113.
201. Suter D.M., Errante L.D., Belotserkovsky V., Forscher P. The Ig superfamily cell adhesion molecule, apCAM, mediates growth cone steering by substrate-cytoskeletal coupling. J. Cell Biol. 141:1998;227-240.
202. Suter D.M., Espindola F.S., Lin C.H., Forscher P., Mooseker M.S. Localization of unconventional myosins V and VI in neuronal growth cones. J. Neurobiol. 42:2000;370-382.
203. Sydor A.M., Su A.L., Wang F.S., Xu A., Jay D.G. Talin and vinculin play distinct roles in filopodial motility in the neuronal growth cone. J. Cell Biol. 134:1996;1197-1207.
204. Tanaka E.M., Kirschner M.W. Microtubule behavior in the growth cones of living neurons during axon elongation. J. Cell Biol. 115:1991;345-363.
205. Tanaka E., Kirschner M.W. The role of microtubules in growth cone turning at substrate boundaries. J. Cell Biol. 128:1995;127-137.
206. Tanaka E., Sabry J. Making the connection. cytoskeletal rearrangements during growth cone guidance Cell. 83:1995;171-176.
207. Tanaka J., Kira M., Sobue K. Gelsolin is localized in neuronal growth cones. Brain Res. Dev. Brain Res. 76:1993;268-271.
208. Tanaka E., Ho T., Kirschner M.W. The role of microtubule dynamics in growth cone motility and axonal growth. J. Cell Biol. 128:1995;139-155.
209. Tennyson V.M. The fine structure of the axon and growth cone of the dorsal root neuroblast of the rabbit embryo. J. Cell Biol. 44:1970;62-79.
210. Tsui H.T., Lankford K.L., Ris H., Klein W.L. Novel organization of microtubules in cultured central nervous system neurons. formation of hairpin loops at ends of maturing neurites J. Neurosci. 4:1984;3002-3013.
211. Verdier-Pinard P., Wang F., Martello L., Burd B., Orr G.A., Horwitz S.B. Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry. Biochemistry. 42:2003;5349-5357.
212. Walker R.A., O'Brien E.T., Pryer N.K., Soboeiro M.F., Voter W.A., Erickson H.P., Salmon E.D. Dynamic instability of individual microtubules analyzed by video light microscopy. rate constants and transition frequencies J. Cell Biol. 107:1988;1437-1448.
213. Wang L., Brown A. Rapid movement of microtubules in axons. Curr. Biol. 12:2002;1496-1501.
214. Watakabe A., Kobayashi R., Helfman D.M. N-tropomodulin. a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin J. Cell Sci. 109:1996;2299-2310.
215. Waterman-Storer C.M., Worthylake R.A., Liu B.P., Burridge K., Salmon E.D. Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts. Nat. Cell Biol. 1:1999;45-50.
216. Weaver A.M., Young M.E., Lee W.L., Cooper J.A. Integration of signals to the Arp2/3 complex. Curr. Opin. Cell Biol. 15:2003;23-30.
217. Welnhofer E.A., Zhao L., Cohan C.S. Actin dynamics and organization during growth cone morphogenesis in Helisoma neurons. Cell Motil. Cytoskeleton. 37:1997;54-71.
218. Welnhofer E.A., Zhao L., Cohan C.S. Calcium influx alters actin bundle dynamics and retrograde flow in Helisoma growth cones. J. Neurosci. 19:1999;7971-7982.
219. Williamson T., Gordon-Weeks P.R., Schachner M., Taylor J. Microtubule reorganization is obligatory for growth cone turning. Proc. Natl. Acad. Sci. USA. 93:1996;15221-15226.
220. Wills Z., Bateman J., Korey C.A., Comer A., Van Vactor D. The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance. Neuron. 22:1999;301-312.
221. Wills Z., Emerson M., Rusch J., Bikoff J., Baum B., Perrimon N., Van Vactor D. A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding. Neuron. 36:2002;611-622.
222. Wittmann T., Waterman-Storer C.M. Cell motility. can Rho GTPases and microtubules point the way? J. Cell Sci. 114:2001;3795-3803.
223. Wittmann T., Bokoch G.M., Waterman-Storer C.M. Regulation of leading edge microtubule and actin dynamics downstream of Rac1. J. Cell Biol. 161:2003;845-851.
224. Yamada K.M., Spooner B.S., Wessells N.K. Axon growth. roles of microfilaments and microtubules Proc. Natl. Acad. Sci. USA. 66:1970;1206-1212.
225. Yamada K.M., Spooner B.S., Wessells N.K. Ultrastructure and function of growth cones and axons of cultured nerve cells. J. Cell Biol. 49:1971;614-635.
226. Yu W., Schwei M.J., Baas P.W. Microtubule transport and assembly during axon growth. J. Cell Biol. 133:1996;151-157.
227. Yuasa-Kawada J., Suzuki R., Kano F., Ohkawara T., Murata M., Noda M. Axonal morphogenesis controlled by antagonistic roles of two CRMP subtypes in microtubule organization. Eur. J. Neurosci. 17:2003;2329-2343.
228. Yuste R., Lanni F., Konnerth A. Imaging Neurons. A Laboratory Manual:2000;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
229. Zakharenko S., Popov S. Dynamics of axonal microtubules regulate the topology of new membrane insertion into the growing neurites. J. Cell Biol. 143:1998;1077-1086.
230. Zhou F.Q., Cohan C.S. Growth cone collapse through coincident loss of actin bundles and leading edge actin without actin depolymerization. J. Cell Biol. 153:2001;1071-1084.
231. Zhou F.Q., Waterman-Storer C.M., Cohan C.S. Focal loss of actin bundles causes microtubule redistribution and growth cone turning. J. Cell Biol. 157:2002;839-849.