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Volumn 22, Issue 13, 2002, Pages 5393-5402

Gephyrin interacts with dynein light chains 1 and 2, components of motor protein complexes

Author keywords

Cytoplasmic dynein; Dlc 1; Dlc 2; Gephyrin; Inhibitory synapse; LC8; Motor protein; Myosin Va; PIN

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; DYNEIN LIGHT CHAIN 1; DYNEIN LIGHT CHAIN 2; GEPHYRIN; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN INHIBITOR; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

EID: 0036663045     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-13-05393.2002     Document Type: Article
Times cited : (167)

References (53)
  • 1
    • 0034659732 scopus 로고    scopus 로고
    • Postsynaptic scaffolds of excitatory and inhibitory synapses in hippocampal neurons: Maintenance of core components independent of actin filaments and microtubules
    • Allison DW, Chervin AS, Gelfand VI, Craig AM (2000) Postsynaptic scaffolds of excitatory and inhibitory synapses in hippocampal neurons: Maintenance of core components independent of actin filaments and microtubules. J Neurosci 20:4545-4554.
    • (2000) J Neurosci , vol.20 , pp. 4545-4554
    • Allison, D.W.1    Chervin, A.S.2    Gelfand, V.I.3    Craig, A.M.4
  • 3
    • 0342419162 scopus 로고
    • Polarity orientation of microtubules in hippocampal neurons: Uniformity in the axon and nonuniformity in the dendrite
    • Baas PW, Deitch JS, Black MM, Banker GA (1988) Polarity orientation of microtubules in hippocampal neurons: Uniformity in the axon and nonuniformity in the dendrite. Proc Natl Acad Sci USA 85:8335-8339.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8335-8339
    • Baas, P.W.1    Deitch, J.S.2    Black, M.M.3    Banker, G.A.4
  • 4
    • 0028210635 scopus 로고
    • Inhibitory neurotransmission in rat spinal cord: Co-localization of glycine- and GABAA-receptors at GABAergic synaptic contacts demonstrated by triple immunofluorescence staining
    • Bohlhalter S, Möhler H, Fritschy JM (1994) Inhibitory neurotransmission in rat spinal cord: Co-localization of glycine- and GABAA-receptors at GABAergic synaptic contacts demonstrated by triple immunofluorescence staining. Brain Res 642:59-69.
    • (1994) Brain Res , vol.642 , pp. 59-69
    • Bohlhalter, S.1    Möhler, H.2    Fritschy, J.M.3
  • 5
    • 0033697715 scopus 로고    scopus 로고
    • The role of selective transport in neuronal protein sorting
    • Burack MA, Silverman MA, Banker G (2000) The role of selective transport in neuronal protein sorting. Neuron 26:465-472.
    • (2000) Neuron , vol.26 , pp. 465-472
    • Burack, M.A.1    Silverman, M.A.2    Banker, G.3
  • 6
    • 0032585033 scopus 로고    scopus 로고
    • Localization of components of glycinergic synapses during rat spinal cord development
    • Colin I, Rostaing P, Augustin A, Triller A (1998) Localization of components of glycinergic synapses during rat spinal cord development. J Comp Neurol 398:359-372.
    • (1998) J Comp Neurol , vol.398 , pp. 359-372
    • Colin, I.1    Rostaing, P.2    Augustin, A.3    Triller, A.4
  • 8
    • 0032924485 scopus 로고    scopus 로고
    • Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic synaptic terminal boutons
    • Dumoulin A, Rostaing P, Bedet C, Lévi S, Isambert MF, Henry JP, Triller A, Gasnier B (1999) Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic synaptic terminal boutons. J Cell Sci 112:811-823.
    • (1999) J Cell Sci , vol.112 , pp. 811-823
    • Dumoulin, A.1    Rostaing, P.2    Bedet, C.3    Lévi, S.4    Isambert, M.F.5    Henry, J.P.6    Triller, A.7    Gasnier, B.8
  • 9
    • 0034627757 scopus 로고    scopus 로고
    • Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering
    • El-Husseini AE, Craven SE, Chetkovich DM, Firestein BL, Schnell E, Aoki C, Bredt DS (2000) Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering. J Cell Biol 148:159-171.
    • (2000) J Cell Biol , vol.148 , pp. 159-171
    • El-Husseini, A.E.1    Craven, S.E.2    Chetkovich, D.M.3    Firestein, B.L.4    Schnell, E.5    Aoki, C.6    Bredt, D.S.7
  • 11
    • 33644665247 scopus 로고    scopus 로고
    • Postsynaptic clustering of major GABAA receptor subtypes requires the γ2 subunit and gephyrin
    • Essrich C, Lorez M, Benson JA, Fritschy JM, Lüscher B (1998) Postsynaptic clustering of major GABAA receptor subtypes requires the γ2 subunit and gephyrin. Nat Neurosci 7:563-571.
    • (1998) Nat Neurosci , vol.7 , pp. 563-571
    • Essrich, C.1    Lorez, M.2    Benson, J.A.3    Fritschy, J.M.4    Lüscher, B.5
  • 12
    • 0032514872 scopus 로고    scopus 로고
    • Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
    • Feng G, Tintrup H, Kirsch J, Nichol MC, Kuhse J, Betz H, Sanes JR (1998) Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity. Science 282:1321-1324.
    • (1998) Science , vol.282 , pp. 1321-1324
    • Feng, G.1    Tintrup, H.2    Kirsch, J.3    Nichol, M.C.4    Kuhse, J.5    Betz, H.6    Sanes, J.R.7
  • 13
    • 0032963006 scopus 로고    scopus 로고
    • Dendritic and postsynaptic protein synthetic machinery
    • Gardiol A, Racca C, Triller A (1999) Dendritic and postsynaptic protein synthetic machinery. J Neurosci 19:168-179.
    • (1999) J Neurosci , vol.19 , pp. 168-179
    • Gardiol, A.1    Racca, C.2    Triller, A.3
  • 14
    • 0035167517 scopus 로고    scopus 로고
    • Identification of a gephyrin-binding motif in the GDP/GTP exchange factor collybistin
    • Grosskreutz Y, Hermann A, Kins S, Fuhrmann JC, Betz H, Kneussel M (2001) Identification of a gephyrin-binding motif in the GDP/GTP exchange factor collybistin. Biol Chem 382:1455-1462.
    • (2001) Biol Chem , vol.382 , pp. 1455-1462
    • Grosskreutz, Y.1    Hermann, A.2    Kins, S.3    Fuhrmann, J.C.4    Betz, H.5    Kneussel, M.6
  • 15
    • 0034529440 scopus 로고    scopus 로고
    • Dynein light chain interacts with NRF-1 and EWG, structurally and functionally related transcription factors from humans and Drosophila
    • Herzig RP, Andersson U, Scarpulla RC (2000) Dynein light chain interacts with NRF-1 and EWG, structurally and functionally related transcription factors from humans and Drosophila. J Cell Sci 113:4263-4273.
    • (2000) J Cell Sci , vol.113 , pp. 4263-4273
    • Herzig, R.P.1    Andersson, U.2    Scarpulla, R.C.3
  • 16
    • 0030028366 scopus 로고    scopus 로고
    • Selective stabilization of tau in axons and microtubule-associated protein 2C in cell bodies and dendrites contributes to polarized localization of cytoskeletal proteins in mature neurons
    • Hirokawa N, Funakoshi T, Sato-Harada R, Kanai Y (1996) Selective stabilization of tau in axons and microtubule-associated protein 2C in cell bodies and dendrites contributes to polarized localization of cytoskeletal proteins in mature neurons. J Cell Biol 132:667-679.
    • (1996) J Cell Biol , vol.132 , pp. 667-679
    • Hirokawa, N.1    Funakoshi, T.2    Sato-Harada, R.3    Kanai, Y.4
  • 17
    • 0032005975 scopus 로고    scopus 로고
    • Kinesin and dynein superfamily proteins in organelle transport and cell division
    • Hirokawa N, Noda Y, Okada Y (1998) Kinesin and dynein superfamily proteins in organelle transport and cell division. Curr Opin Cell Biol 10:60-73.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 60-73
    • Hirokawa, N.1    Noda, Y.2    Okada, Y.3
  • 18
    • 0029858301 scopus 로고    scopus 로고
    • PIN: An associated protein inhibitor of neuronal nitric oxide synthase
    • Jaffrey SR, Snyder SH (1996) PIN: An associated protein inhibitor of neuronal nitric oxide synthase. Science 274:774-777.
    • (1996) Science , vol.274 , pp. 774-777
    • Jaffrey, S.R.1    Snyder, S.H.2
  • 19
    • 0034677929 scopus 로고    scopus 로고
    • The dynein microtubule motor
    • King SM (2000) The dynein microtubule motor. Biochim Biophys Acta 1496:60-75.
    • (2000) Biochim Biophys Acta , vol.1496 , pp. 60-75
    • King, S.M.1
  • 20
  • 21
    • 0033994755 scopus 로고    scopus 로고
    • Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin
    • Kins S, Betz H, Kirsch A (2000) Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin. Nat Neurosci 3:22-29.
    • (2000) Nat Neurosci , vol.3 , pp. 22-29
    • Kins, S.1    Betz, H.2    Kirsch, A.3
  • 22
    • 0028998303 scopus 로고
    • The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton
    • Kirsch J, Betz H (1995) The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeleton. J Neurosci 15:4148-4156.
    • (1995) J Neurosci , vol.15 , pp. 4148-4156
    • Kirsch, J.1    Betz, H.2
  • 24
    • 0027723681 scopus 로고
    • Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons
    • Kirsch J, Wolters I, Triller A, Betz H (1993) Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons. Nature 366:745-748.
    • (1993) Nature , vol.366 , pp. 745-748
    • Kirsch, J.1    Wolters, I.2    Triller, A.3    Betz, H.4
  • 25
    • 0028848501 scopus 로고
    • Targeting of glycine receptor subunits to gephyrin-rich domains in transfected human embryonic kidney cells
    • Kirsch J, Kuhse J, Betz H (1995) Targeting of glycine receptor subunits to gephyrin-rich domains in transfected human embryonic kidney cells. Mol Cell Neurosci 6:450-461.
    • (1995) Mol Cell Neurosci , vol.6 , pp. 450-461
    • Kirsch, J.1    Kuhse, J.2    Betz, H.3
  • 26
    • 0034284148 scopus 로고    scopus 로고
    • Clustering of inhibitory neurotransmitter receptors at developing postsynaptic sites: The membrane activation model
    • Kneussel M, Betz H (2000) Clustering of inhibitory neurotransmitter receptors at developing postsynaptic sites: The membrane activation model. Trends Neurosci 23:429-435.
    • (2000) Trends Neurosci , vol.23 , pp. 429-435
    • Kneussel, M.1    Betz, H.2
  • 29
    • 0033560859 scopus 로고    scopus 로고
    • Quantal size is correlated with receptor cluster area at glycinergic synapses in the rat brainstem
    • 516.2
    • Lim R, Alvarez FJ, Walmsley B (1999) Quantal size is correlated with receptor cluster area at glycinergic synapses in the rat brainstem. J Physiol (Lond) 516.2:505-512.
    • (1999) J Physiol (Lond) , pp. 505-512
    • Lim, R.1    Alvarez, F.J.2    Walmsley, B.3
  • 30
    • 0032005206 scopus 로고    scopus 로고
    • Cytoskeletal proteins and golgi dynamics
    • Lippincott-Schwartz J (1998) Cytoskeletal proteins and golgi dynamics. Curr Opin Cell Biol 10:52-59.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 52-59
    • Lippincott-Schwartz, J.1
  • 31
    • 0035112736 scopus 로고    scopus 로고
    • Fast and reversible trapping of surface glycine receptors by gephyrin
    • Meier J, Vannier C, Serge A, Triller A, Choquet D (2001) Fast and reversible trapping of surface glycine receptors by gephyrin. Nat Neurosci 4:253-260.
    • (2001) Nat Neurosci , vol.4 , pp. 253-260
    • Meier, J.1    Vannier, C.2    Serge, A.3    Triller, A.4    Choquet, D.5
  • 32
    • 0029124881 scopus 로고
    • Identification of a gephyrin binding motif on the glycine receptor β subunit
    • Meyer G, Kirsch J, Betz H, Langosch D (1995) Identification of a gephyrin binding motif on the glycine receptor β subunit. Neuron 15:563-572.
    • (1995) Neuron , vol.15 , pp. 563-572
    • Meyer, G.1    Kirsch, J.2    Betz, H.3    Langosch, D.4
  • 33
    • 0034660288 scopus 로고    scopus 로고
    • Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin V, dynein
    • Naisbitt S, Valtschanoff J, Allison DW, Sala C, Kim E, Craig AM, Weinberg RJ, Sheng M (2000) Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin V, dynein. J Neurosci 20:4524-4534.
    • (2000) J Neurosci , vol.20 , pp. 4524-4534
    • Naisbitt, S.1    Valtschanoff, J.2    Allison, D.W.3    Sala, C.4    Kim, E.5    Craig, A.M.6    Weinberg, R.J.7    Sheng, M.8
  • 34
    • 0021751227 scopus 로고
    • Monoclonal antibodies and peptide mapping reveal structural similarities between the subunits of the glycine receptor of rat spinal cord
    • Pfeiffer F, Simler R, Grenningloh G, Betz H (1984) Monoclonal antibodies and peptide mapping reveal structural similarities between the subunits of the glycine receptor of rat spinal cord. Proc Natl Acad Sci USA 81:7224-7227.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 7224-7227
    • Pfeiffer, F.1    Simler, R.2    Grenningloh, G.3    Betz, H.4
  • 36
    • 0033104996 scopus 로고    scopus 로고
    • The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
    • Puthalakath H, Huang DCS, O'Reilly LA, King SM, Strasser A (1999) The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell 3:287-296.
    • (1999) Mol Cell , vol.3 , pp. 287-296
    • Puthalakath, H.1    Huang, D.C.S.2    O'Reilly, L.A.3    King, S.M.4    Strasser, A.5
  • 39
    • 0033787039 scopus 로고    scopus 로고
    • The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes
    • Schnorrer F, Bohmann K, Nüsslein-Volhard C (2000) The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes. Nat Cell Biol 2:185-190.
    • (2000) Nat Cell Biol , vol.2 , pp. 185-190
    • Schnorrer, F.1    Bohmann, K.2    Nüsslein-Volhard, C.3
  • 40
    • 0035860322 scopus 로고    scopus 로고
    • Crystal structure of human gephyrin and plant Cnx1 G domains: Comparative analysis and functional implications
    • Schwarz G, Schrader N, Mendel RR, Hecht HJ, Schindelin H (2001) Crystal structure of human gephyrin and plant Cnx1 G domains: Comparative analysis and functional implications. J Mol Biol 312:405-418.
    • (2001) J Mol Biol , vol.312 , pp. 405-418
    • Schwarz, G.1    Schrader, N.2    Mendel, R.R.3    Hecht, H.J.4    Schindelin, H.5
  • 41
    • 0034625631 scopus 로고    scopus 로고
    • Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport
    • Setou M, Nakagawa T, Seog DH, Hirokawa N (2000) Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science 288:1796-1802.
    • (2000) Science , vol.288 , pp. 1796-1802
    • Setou, M.1    Nakagawa, T.2    Seog, D.H.3    Hirokawa, N.4
  • 42
    • 0033860051 scopus 로고    scopus 로고
    • Ligand-gated ion channel interactions with cytoskeletal and signaling proteins
    • Sheng M, Pak DT (2000) Ligand-gated ion channel interactions with cytoskeletal and signaling proteins. Annu Rev Physiol 62:755-778.
    • (2000) Annu Rev Physiol , vol.62 , pp. 755-778
    • Sheng, M.1    Pak, D.T.2
  • 43
    • 0035816706 scopus 로고    scopus 로고
    • X-ray crystal structure of the trimeric N-terminal domain of gephyrin
    • Sola M, Kneussel M, Heck IS, Betz H, Weissenhorn W (2001) X-ray crystal structure of the trimeric N-terminal domain of gephyrin. J Biol Chem 276:25294-25301.
    • (2001) J Biol Chem , vol.276 , pp. 25294-25301
    • Sola, M.1    Kneussel, M.2    Heck, I.S.3    Betz, H.4    Weissenhorn, W.5
  • 44
    • 0033603239 scopus 로고    scopus 로고
    • Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain tctex-1
    • Tai AW, Chuang JZ, Bode C, Wolfrum U, Sung CH (1999) Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain tctex-1. Cell 97:877-887.
    • (1999) Cell , vol.97 , pp. 877-887
    • Tai, A.W.1    Chuang, J.Z.2    Bode, C.3    Wolfrum, U.4    Sung, C.H.5
  • 45
    • 0031791314 scopus 로고    scopus 로고
    • Solution structure of a protein inhibitor of neuronal nitric oxide synthase
    • Tochio H, Ohki S, Zhang Q LiM, Zhang M (1998) Solution structure of a protein inhibitor of neuronal nitric oxide synthase. Nat Struct Biol 5:965-969.
    • (1998) Nat Struct Biol , vol.5 , pp. 965-969
    • Tochio, H.1    Ohki, S.2    Zhang, Q.3    Li, M.4    Zhang, M.5
  • 46
    • 0029927346 scopus 로고    scopus 로고
    • Colocalization of GABA, glycine, and their receptors at synapses in the rat spinal cord
    • Todd AJ, Watt C, Spike RC, Sieghart W (1996) Colocalization of GABA, glycine, and their receptors at synapses in the rat spinal cord. J Neurosci 16:974-982.
    • (1996) J Neurosci , vol.16 , pp. 974-982
    • Todd, A.J.1    Watt, C.2    Spike, R.C.3    Sieghart, W.4
  • 47
    • 0011735442 scopus 로고    scopus 로고
    • The central neuron
    • Graham DI, Lantos PL, eds. London: Arnold
    • Triller A, Sotelo C (1997) The central neuron. In: Grenfield's Neuropathology, Ed. 6 (Graham DI, Lantos PL, eds), pp 3-31. London: Arnold.
    • (1997) Grenfield's Neuropathology, Ed. 6 , pp. 3-31
    • Triller, A.1    Sotelo, C.2
  • 48
    • 0022415961 scopus 로고
    • Distribution of glycine receptors at central synapses: An immunoelectron microscopy study
    • Triller A, Cluzeaud F, Pfeiffer F, Betz H, Korn H (1985) Distribution of glycine receptors at central synapses: An immunoelectron microscopy study. J Cell Biol 101:683-688.
    • (1985) J Cell Biol , vol.101 , pp. 683-688
    • Triller, A.1    Cluzeaud, F.2    Pfeiffer, F.3    Betz, H.4    Korn, H.5
  • 49
    • 0023245759 scopus 로고
    • Gamma-aminobutyric acid-containing terminals can be apposed to glycine receptors at central synapses
    • Triller A, Cluzeaud F, Korn H (1987) Gamma-aminobutyric acid-containing terminals can be apposed to glycine receptors at central synapses. J Cell Biol 104:947-956.
    • (1987) J Cell Biol , vol.104 , pp. 947-956
    • Triller, A.1    Cluzeaud, F.2    Korn, H.3
  • 52
    • 0034880831 scopus 로고    scopus 로고
    • The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin
    • Xiang S, Nichols J, Rajagopalan KV, Schindelin H (2001) The crystal structure of Escherichia coli MoeA and its relationship to the multifunctional protein gephyrin. Structure 9:299-310.
    • (2001) Structure , vol.9 , pp. 299-310
    • Xiang, S.1    Nichols, J.2    Rajagopalan, K.V.3    Schindelin, H.4
  • 53
    • 0031442806 scopus 로고    scopus 로고
    • Enlightening the postsynaptic density
    • Ziff EB (1997) Enlightening the postsynaptic density. Neuron 19:1163-1174.
    • (1997) Neuron , vol.19 , pp. 1163-1174
    • Ziff, E.B.1


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