-
1
-
-
0028988158
-
Kip2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
-
Kip2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev 1995; 9:639-649
-
(1995)
Genes Dev
, vol.9
, pp. 639-649
-
-
Lee, M.H.1
Reynisdottir, I.2
Massague, J.3
-
2
-
-
0028988159
-
Cip1 CDK inhibitor family, is a candidate tumor suppressor gene
-
Cip1 CDK inhibitor family, is a candidate tumor suppressor gene. Genes Dev 1995; 9:650-662
-
(1995)
Genes Dev
, vol.9
, pp. 650-662
-
-
Matsuoka, S.1
Edwards, M.C.2
Bai, C.3
Parker, S.4
Zhang, P.5
Baldini, A.6
-
3
-
-
0028363519
-
1 cyclin-CDK protein kinase activity, is related to p21
-
1 cyclin-CDK protein kinase activity, is related to p21. Cell 1994; 78:67-74.
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Toyoshima, H.1
Hunter, T.2
-
4
-
-
0028176483
-
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
-
DOI 10.1016/0092-8674(94)90572-X
-
Polyak K, Lee MH, Erdjument-Bromage H, Koff A, Roberts JM, Tempst P, et al. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 1994; 78:59-66. (Pubitemid 2117026)
-
(1994)
Cell
, vol.78
, Issue.1
, pp. 59-66
-
-
Polyak, K.1
Lee Mong, H.2
Erdjument-Bromage, H.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
Massague, J.7
-
5
-
-
0346101745
-
Kip2 Regulates Actin Dynamics by Binding and Translocating LIM-kinase 1 to the Nucleus
-
DOI 10.1074/jbc.M309334200
-
Yokoo T, Toyoshima H, Miura M, Wang Y, Iida KT, Suzuki H, et al. p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus. J Biol Chem 2003; 278:52919-52923 (Pubitemid 38035893)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.52
, pp. 52919-52923
-
-
Yokoo, T.1
Toyoshima, H.2
Miura, M.3
Wang, Y.4
Iida, K.T.5
Suzuki, H.6
Sone, H.7
Shimano, H.8
Gotoda, T.9
Nishimori, S.10
Tanaka, K.11
Yamada, N.12
-
9
-
-
0030010591
-
Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia and pituitary tumors
-
Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia and pituitary tumors. Cell 1996; 85:707-720
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inomata, A.4
Inoue, T.5
Shishido, N.6
-
13
-
-
65249113847
-
Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model
-
Susaki E, Nakayama K, Yamasaki L, Nakayama KI. Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model. Proc Natl Acad Sci USA 2009; 106:5192-5197
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 5192-5197
-
-
Susaki, E.1
Nakayama, K.2
Yamasaki, L.3
Nakayama, K.I.4
-
16
-
-
24044555556
-
1 phase
-
DOI 10.1074/jbc.M500866200
-
Kotoshiba S, Kamura T, Hara T, Ishida N, Nakayama KI. Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase. J Biol Chem 2005; 280:17694-17700 (Pubitemid 41389006)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.18
, pp. 17694-17700
-
-
Kotoshibai, S.1
Kamura, T.2
Hara, T.3
Ishida, N.4
Nakayama, K.I.5
-
18
-
-
63049131393
-
Kip1 distinguish pituitary progenitor cell cycle exit from cell cycle reentry of differentiated cells
-
Kip1 distinguish pituitary progenitor cell cycle exit from cell cycle reentry of differentiated cells. Mol Cell Biol 2009; 29:1895-1908
-
(2009)
Mol Cell Biol
, vol.29
, pp. 1895-1908
-
-
Bilodeau, S.1
Roussel-Gervais, A.2
Drouin, J.3
-
19
-
-
34250012532
-
Kip2 in the intracellular timer that controls oligodendrocyte differentiation
-
Kip2 in the intracellular timer that controls oligodendrocyte differentiation. J Neurosci 2007; 27:6185-6196
-
(2007)
J Neurosci
, vol.27
, pp. 6185-6196
-
-
Dugas, J.C.1
Ibrahim, A.2
Barres, B.A.3
-
20
-
-
0033825384
-
Kip2 regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina
-
Kip2 regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina. Development 2000; 127:3593-3605
-
(2000)
Development
, vol.127
, pp. 3593-3605
-
-
Dyer, M.A.1
Cepko, C.L.2
-
21
-
-
33748776298
-
P57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors
-
DOI 10.1016/j.ydbio.2006.05.036, PII S001216060600875X
-
Georgia S, Soliz R, Li M, Zhang P, Bhushan A. p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors. Dev Biol 2006; 298:22-31. (Pubitemid 44414792)
-
(2006)
Developmental Biology
, vol.298
, Issue.1
, pp. 22-31
-
-
Georgia, S.1
Soliz, R.2
Li, M.3
Zhang, P.4
Bhushan, A.5
-
22
-
-
33845653116
-
A cell-autonomous requirement for Cip/Kip cyclin-kinase inhibitors in regulating neuronal cell cycle exit but not differentiation in the developing spinal cord
-
DOI 10.1016/j.ydbio.2006.10.035, PII S0012160606013285
-
Gui H, Li S, Matise MP. A cell-autonomous requirement for Cip/Kip cyclin-kinase inhibitors in regulating neuronal cell cycle exit but not differentiation in the developing spinal cord. Dev Biol 2007; 301:14-26. (Pubitemid 44958402)
-
(2007)
Developmental Biology
, vol.301
, Issue.1
, pp. 14-26
-
-
Gui, H.1
Li, S.2
Matise, M.P.3
-
24
-
-
9444242683
-
Shared role of the pRB-related p130 and p107 proteins in limb development
-
Cobrinik D, Lee MH, Hannon G, Mulligan G, Bronson RT, Dyson N, et al. Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev 1996; 10:1633-1644 (Pubitemid 26268868)
-
(1996)
Genes and Development
, vol.10
, Issue.13
, pp. 1633-1644
-
-
Cobrinik, D.1
Lee, M.-H.2
Hannon, G.3
Mulligan, G.4
Bronson, R.T.5
Dyson, N.6
Harlow, E.7
Beach, D.8
Weinberg, R.A.9
Jacks, T.10
-
25
-
-
0027934570
-
P53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
-
DOI 10.1038/371072a0
-
Morgenbesser SD, Williams BO, Jacks T, DePinho RA. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 1994; 371:72-74 (Pubitemid 24277466)
-
(1994)
Nature
, vol.371
, Issue.6492
, pp. 72-74
-
-
Morgenbesser, S.D.1
Williams, B.O.2
Jacks, T.3
Depinho, R.A.4
-
26
-
-
0029910628
-
Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system
-
Macleod KF, Hu Y, Jacks T. Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J 1996; 15:6178-6188 (Pubitemid 26397890)
-
(1996)
EMBO Journal
, vol.15
, Issue.22
, pp. 6178-6188
-
-
Macleod, K.F.1
Hu, Y.2
Jacks, T.3
-
27
-
-
0034619773
-
E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses
-
DOI 10.1038/sj.onc.1203996
-
Liu Y, Zacksenhaus E. E2F1 mediates ectopic proliferation and stage-specific p53- dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses. Oncogene 2000; 19:6065-6073 (Pubitemid 32039381)
-
(2000)
Oncogene
, vol.19
, Issue.52
, pp. 6065-6073
-
-
Liu, Y.1
Zacksenhaus, E.2
-
28
-
-
0032159103
-
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
-
Tsai KY, Hu Y, Macleod KF, Crowley D, Yamasaki L, Jacks T. Mutation of E2F1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos. Mol Cell 1998; 2:293-304. (Pubitemid 128379270)
-
(1998)
Molecular Cell
, vol.2
, Issue.3
, pp. 293-304
-
-
Tsai, K.Y.1
Hu, Y.2
Macleod, K.F.3
Crowley, D.4
Yamasaki, L.5
Jacks, T.6
-
29
-
-
0035997933
-
Specificity of E2F1, E2F2 and E2F3 in mediating phenotypes induced by loss of Rb
-
Saavedra HI, Wu L, de Bruin A, Timmers C, Rosol TJ, Weinstein M, et al. Specificity of E2F1, E2F2 and E2F3 in mediating phenotypes induced by loss of Rb. Cell Growth Differ 2002; 13:215-225
-
(2002)
Cell Growth Differ
, vol.13
, pp. 215-225
-
-
Saavedra, H.I.1
Wu, L.2
De Bruin, A.3
Timmers, C.4
Rosol, T.J.5
Weinstein, M.6
-
30
-
-
0032493350
-
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
-
DOI 10.1073/pnas.95.14.8292
-
Kamijo T, Weber JD, Zambetti G, Zindy F, Roussel MF, Sherr CJ. Functional and physical interactions of the ARF tumor suppressor with p53 and MDM2. Proc Natl Acad Sci USA 1998; 95:8292-8297 (Pubitemid 28326106)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.14
, pp. 8292-8297
-
-
Kamijo, T.1
Weber, J.D.2
Zambetti, G.3
Zindy, F.4
Roussel, M.F.5
Sherr, C.J.6
-
31
-
-
0032549704
-
ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 1998; 92:713-723
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
-
32
-
-
0032169516
-
ARF, participates in a regulatory feedback loop with p53 and MDM2
-
ARF, participates in a regulatory feedback loop with p53 and MDM2. EMBO J 1998; 17:5001-5014
-
(1998)
EMBO J
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
-
33
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
DOI 10.1016/S0092-8674(00)81401-4
-
Zhang Y, Xiong Y, Yarbrough WG. ARF promotes MDM2 degradation and stabilizes p53: ARF-Ink4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 1998; 92:725-734 (Pubitemid 28155312)
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
36
-
-
0036311177
-
E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis
-
Rogoff HA, Pickering MT, Debatis ME, Jones S, Kowalik TF. E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis. Mol Cell Biol 2002; 22:5308-5318
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5308-5318
-
-
Rogoff, H.A.1
Pickering, M.T.2
Debatis, M.E.3
Jones, S.4
Kowalik, T.F.5
-
37
-
-
0036168192
-
ARF differentially modulates apoptosis induced by E2F1 and Myc
-
Russell JL, Powers JT, Rounbehler RJ, Rogers PM, Conti CJ, Johnson DG. ARF differentially modulates apoptosis induced by E2F1 and Myc. Mol Cell Biol 2002; 22:1360-1368
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1360-1368
-
-
Russell, J.L.1
Powers, J.T.2
Rounbehler, R.J.3
Rogers, P.M.4
Conti, C.J.5
Johnson, D.G.6
-
38
-
-
0036132647
-
Novel function of the cyclin a binding site of E2F in regulating p53-induced apoptosis in response to DNA damage
-
Hsieh JK, Yap D, O'Connor DJ, Fogal V, Fallis L, Chan F, et al. Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage. Mol Cell Biol 2002; 22:78-93.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 78-93
-
-
Hsieh, J.K.1
Yap, D.2
O'Connor, D.J.3
Fogal, V.4
Fallis, L.5
Chan, F.6
-
39
-
-
3543144346
-
E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis
-
Powers JT, Hong S, Mayhew CN, Rogers PM, Knudsen ES, Johnson DG. E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis. Mol Cancer Res 2004; 2:203-214
-
(2004)
Mol Cancer Res
, vol.2
, pp. 203-214
-
-
Powers, J.T.1
Hong, S.2
Mayhew, C.N.3
Rogers, P.M.4
Knudsen, E.S.5
Johnson, D.G.6
-
40
-
-
0035921928
-
Archipelago regulates cyclin e levels in Drosophila and is mutated in human cancer cell lines
-
Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK. Archipelago regulates cyclin E levels in Drosophila and is mutated in human cancer cell lines. Nature 2001; 413:311-316
-
(2001)
Nature
, vol.413
, pp. 311-316
-
-
Moberg, K.H.1
Bell, D.W.2
Wahrer, D.C.3
Haber, D.A.4
Hariharan, I.K.5
-
41
-
-
0035921849
-
Human F-box protein hCDC4 targets cyclin e for proteolysis and is mutated in a breast cancer cell line
-
Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI. Human F-box protein hCDC4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line. Nature 2001; 413:316-322
-
(2001)
Nature
, vol.413
, pp. 316-322
-
-
Strohmaier, H.1
Spruck, C.H.2
Kaiser, P.3
Won, K.A.4
Sangfelt, O.5
Reed, S.I.6
-
43
-
-
2942614705
-
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7
-
Yada M, Hatakeyama S, Kamura T, Nishiyama M, Tsunematsu R, Imaki H, et al. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7. EMBO J 2004; 23:2116-2125
-
(2004)
EMBO J
, vol.23
, pp. 2116-2125
-
-
Yada, M.1
Hatakeyama, S.2
Kamura, T.3
Nishiyama, M.4
Tsunematsu, R.5
Imaki, H.6
-
44
-
-
2942650133
-
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
-
Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, et al. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation- dependent c-Myc protein degradation. Proc Natl Acad Sci USA 2004; 101:9085-9090
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9085-9090
-
-
Welcker, M.1
Orian, A.2
Jin, J.3
Grim, J.E.4
Harper, J.W.5
Eisenman, R.N.6
-
45
-
-
0030659821
-
Sel-10, a negative regulator of Lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
-
Hubbard EJ, Wu G, Kitajewski J, Greenwald I. Sel-10, a negative regulator of Lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. Genes Dev 1997; 11:3182-3193
-
(1997)
Genes Dev
, vol.11
, pp. 3182-3193
-
-
Hubbard, E.J.1
Wu, G.2
Kitajewski, J.3
Greenwald, I.4
-
46
-
-
0035860804
-
Functional interaction between Sel-10, an F-box protein, and the nuclear form of activated Notch1 receptor
-
Gupta-Rossi N, Le Bail O, Gonen H, Brou C, Logeat F, Six E, et al. Functional interaction between Sel-10, an F-box protein, and the nuclear form of activated Notch1 receptor. J Biol Chem 2001; 276:34371-34378
-
(2001)
J Biol Chem
, vol.276
, pp. 34371-34378
-
-
Gupta-Rossi, N.1
Le Bail, O.2
Gonen, H.3
Brou, C.4
Logeat, F.5
Six, E.6
-
47
-
-
0035929669
-
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
-
Oberg C, Li J, Pauley A, Wolf E, Gurney M, Lendahl U. The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog. J Biol Chem 2001; 276:35847-35853
-
(2001)
J Biol Chem
, vol.276
, pp. 35847-35853
-
-
Oberg, C.1
Li, J.2
Pauley, A.3
Wolf, E.4
Gurney, M.5
Lendahl, U.6
-
48
-
-
0034791336
-
Sel-10 is an inhibitor of Notch signaling that targets Notch for ubiquitin-mediated protein degradation
-
Wu G, Lyapina S, Das I, Li J, Gurney M, Pauley A, et al. Sel-10 is an inhibitor of Notch signaling that targets Notch for ubiquitin-mediated protein degradation. Mol Cell Biol 2001; 21:7403-7415
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7403-7415
-
-
Wu, G.1
Lyapina, S.2
Das, I.3
Li, J.4
Gurney, M.5
Pauley, A.6
-
50
-
-
36549071481
-
Conditional inactivation of Fbxw7 impairs cell cycle exit during T cell differentiation and results in lymphomatogenesis
-
Onoyama I, Tsunematsu R, Matsumoto A, Kimura T, De Alboran IM, Nakayama K, et al. Conditional inactivation of Fbxw7 impairs cell cycle exit during T cell differentiation and results in lymphomatogenesis. J Exp Med 2007; 204:2875-2888
-
(2007)
J Exp Med
, vol.204
, pp. 2875-2888
-
-
Onoyama, I.1
Tsunematsu, R.2
Matsumoto, A.3
Kimura, T.4
De Alboran, I.M.5
Nakayama, K.6
-
51
-
-
55849100682
-
Fbxw7 in cell cycle exit and stem cell maintenance: Insight from gene-targeted mice
-
Onoyama I, Nakayama KI. Fbxw7 in cell cycle exit and stem cell maintenance: insight from gene-targeted mice. Cell Cycle 2008; 7:3307-3313
-
(2008)
Cell Cycle
, vol.7
, pp. 3307-3313
-
-
Onoyama, I.1
Nakayama, K.I.2
-
52
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden KH, Prives C. Blinded by the light: the growing complexity of p53. Cell 2009; 137:413-431
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
53
-
-
65549120715
-
Modes of p53 regulation
-
Kruse JP, Gu W. Modes of p53 regulation. Cell 2009; 137:609-622
-
(2009)
Cell
, vol.137
, pp. 609-622
-
-
Kruse, J.P.1
Gu, W.2
-
54
-
-
59649116006
-
CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis
-
Nishiyama M, Oshikawa K, Tsukada Y, Nakagawa T, Iemura S, Natsume T, et al. CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis. Nat Cell Biol 2009; 11:172-182
-
(2009)
Nat Cell Biol
, vol.11
, pp. 172-182
-
-
Nishiyama, M.1
Oshikawa, K.2
Tsukada, Y.3
Nakagawa, T.4
Iemura, S.5
Natsume, T.6
-
56
-
-
66249136447
-
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
-
Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature 2009; 459:428-432
-
(2009)
Nature
, vol.459
, pp. 428-432
-
-
Spencer, S.L.1
Gaudet, S.2
Albeck, J.G.3
Burke, J.M.4
Sorger, P.K.5
-
57
-
-
53749085729
-
Cytokine-induced signaling networks prioritize dynamic range over signal strength
-
Janes KA, Reinhardt HC, Yaffe MB. Cytokine-induced signaling networks prioritize dynamic range over signal strength. Cell 2008; 135:343-354
-
(2008)
Cell
, vol.135
, pp. 343-354
-
-
Janes, K.A.1
Reinhardt, H.C.2
Yaffe, M.B.3
|