Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27Kip1 and p57Kip2 during mouse development

Anatomy and Embryology

Volumn 203, Issue 2, 2001, Pages 77-87

  Nagahama, H ^a,b,c   Hatakeyama, S ^a,b   Nakayama, K ^a,b   Nagata, M ^d   Tomita, K ^c   Nakayama, K I ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Cell cycle; Embryogenesis; Immunohistochemistry; Knockout mice; Proliferation

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; PROTEIN P27; PROTEIN P57;

ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; CELL CYCLE; CELL PROLIFERATION; EMBRYO; EMBRYO DEVELOPMENT; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADRENAL CORTEX; ADRENAL MEDULLA; AGING; ANIMALS; ANTIBODY SPECIFICITY; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASE INHIBITOR P57; EMBRYONIC AND FETAL DEVELOPMENT; FLUORESCENT ANTIBODY TECHNIQUE; GROWTH; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; NUCLEAR PROTEINS; ORGAN SPECIFICITY; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 0035091852     PISSN: 03402061     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004290000146     Document Type: Article

References (44)

1. Ontogenesis of the glomerular C3b receptor (CR1) in fetal human kidney
2. Radiation-induced cell cycle arrest compromised by p21 deficiency
3. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
4. Kip1 protein: Prognostic implications in primary breast cancer
5. Requirement for a functional Rb-1 gene in murine development
6. CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
7. WAF1/CIP1 expression in normal and neoplastic tissues
8. Kip1 is haplo-insufficient for tumour suppression
9. Kip1-deficient mice
10. Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme
11. Waf1/Cip1 expression in normal human tissues
12. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD
13. Kip2, a cyclin-dependent kinase inhibitor, in mouse
14. Kip2 is mutated in Beckwith-Wiedemann syndrome
15. Multiple genetic loci within 11p15 defined by Beckwith-Wiedemann syndrome rearrangement breakpoints and subchromosomal transferable fragments
16. Effects of an Rb mutation in the mouse
17. Kip1
18. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
19. KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
20. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
21. Kip1 allows cell proliferation in the postnatal and adult organ of corti
22. CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene
23. KIP2, on chromosome 11p15
24. Principles of CDK regulation
25. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
26. p27 expression and gastric carcinoma
27. Synaptopodin: An actin-associated protein in telencephalic dendrites and renal podocytes
28. Cell cycle regulation and differentiation in the human podocyte lineage
29. Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
30. Kip1, polyploidy, and centrosome overduplication
31. Cip/Kip cyclin-dependent kinase inhibitors: Brakes of the cell cycle engine during development
32. Cip1 in muscle and other terminally differentiating cells
33. Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
34. Cancer cell cycles
35. CDK inhibitors: Positive and negative regulators of G1-phase progression
36. Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase
37. Kip1 degradation and induces S phase in quiescent cells
38. Kip2, exhibit skeletal abnormalities and growth retardation
39. KIP2 defines a new imprinted domain on chromosome 11p but is not a tumour suppressor gene in Wilms tumour
40. Skp2 complex through phosphorylated Thr187 in p27
41. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
42. Kip2 results in increased apoptosis and delayed differentiation during mouse development
43. KIP2 indicates a role in Beckwith-Wiedemann syndrome
44. KIP2 in the control of tissue growth and development