메뉴 건너뛰기




Volumn 2, Issue 5, 2009, Pages 383-392

Natural killer T cells and the regulation of asthma

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; ALPHA GALACTOSYLCERAMIDE; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 25; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 9; OVALBUMIN; OZONE; T LYMPHOCYTE RECEPTOR;

EID: 69249114907     PISSN: 19330219     EISSN: None     Source Type: Journal    
DOI: 10.1038/mi.2009.96     Document Type: Review
Times cited : (62)

References (147)
  • 4
    • 58149119493 scopus 로고    scopus 로고
    • Gene-environment interactions in asthma
    • quiz 2-3
    • von Mutius, E. Gene-environment interactions in asthma. J. Allergy Clin. Immunol. 123, 3-11; quiz 2-3 (2009).
    • (2009) J. Allergy Clin. Immunol , vol.123 , pp. 3-11
    • von Mutius, E.1
  • 5
    • 40049100646 scopus 로고    scopus 로고
    • Discovering susceptibility genes for asthma and allergy
    • Vercelli, D. Discovering susceptibility genes for asthma and allergy. Nat. Rev. Immunol. 8, 169-182 (2008).
    • (2008) Nat. Rev. Immunol , vol.8 , pp. 169-182
    • Vercelli, D.1
  • 6
    • 52049087356 scopus 로고    scopus 로고
    • Endotyping asthma: New insights into key pathogenic mechanisms in a complex, heterogeneous disease
    • Anderson, G.P. Endotyping asthma: New insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet 372, 1107-1119 (2008).
    • (2008) Lancet , vol.372 , pp. 1107-1119
    • Anderson, G.P.1
  • 7
    • 85185149631 scopus 로고    scopus 로고
    • National Heart Lung and Blood Institute. Title: Expert Panel Report 3 (EPR3): Guidelines for the Diagnosis and Management of Asthma. 2007, Contract no.: Document no item no. 08-4051.
    • National Heart Lung and Blood Institute. Title: Expert Panel Report 3 (EPR3): Guidelines for the Diagnosis and Management of Asthma. 2007, Contract no.: Document no item no. 08-4051.
  • 8
    • 0024491638 scopus 로고
    • Association of asthma with serum IgE levels and skin-test reactivity to allergens
    • Burrows, B., Martinez, F.D., Halonen, M., Barbee, R.A. & Cline, M.G. Association of asthma with serum IgE levels and skin-test reactivity to allergens. N. Engl. J. Med. 320, 271-277 (1989).
    • (1989) N. Engl. J. Med , vol.320 , pp. 271-277
    • Burrows, B.1    Martinez, F.D.2    Halonen, M.3    Barbee, R.A.4    Cline, M.G.5
  • 9
    • 0032968706 scopus 로고    scopus 로고
    • Immunologic basis of antigen-induced airway hyperresponsiveness
    • Wills-Karp, M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu. Rev. Immunol. 17, 255-281 (1999).
    • (1999) Annu. Rev. Immunol , vol.17 , pp. 255-281
    • Wills-Karp, M.1
  • 10
    • 0026610142 scopus 로고
    • Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
    • Robinson, D.S. et al. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326 298-304 (1992).
    • (1992) N. Engl. J. Med , vol.326 , pp. 298-304
    • Robinson, D.S.1
  • 11
    • 0030854183 scopus 로고    scopus 로고
    • The genetics of allergen-induced airway hyperresponsiveness in mice
    • Wills-Karp, M. & Ewart, S.L. The genetics of allergen-induced airway hyperresponsiveness in mice. Am. J. Respir. Crit. Care Med. 156 (4 Part 2), S89-S96 (1997).
    • (1997) Am. J. Respir. Crit. Care Med , vol.156 , Issue.4 PART 2
    • Wills-Karp, M.1    Ewart, S.L.2
  • 12
    • 0028870592 scopus 로고
    • Asthma and wheezing in the first six years of life
    • Martinez, F.D. et al. Asthma and wheezing in the first six years of life. N. Engl. J. Med. 332, 133-138 (1995).
    • (1995) N. Engl. J. Med , vol.332 , pp. 133-138
    • Martinez, F.D.1
  • 13
    • 0028455633 scopus 로고
    • Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia
    • Gavett, S.H., Chen, X., Finkelman, F. & Wills-Karp, M. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am. J. Respir. Cell Mol. Biol. 10, 587-593 (1994).
    • (1994) Am. J. Respir. Cell Mol. Biol , vol.10 , pp. 587-593
    • Gavett, S.H.1    Chen, X.2    Finkelman, F.3    Wills-Karp, M.4
  • 14
    • 2542486456 scopus 로고    scopus 로고
    • Asthma: Mechanisms of disease persistence and progression
    • Cohn, L., Elias, J.A. & Chupp, G.L. Asthma: Mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22, 789-815 (2004).
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 789-815
    • Cohn, L.1    Elias, J.A.2    Chupp, G.L.3
  • 15
    • 35348909044 scopus 로고    scopus 로고
    • Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: Results of two phase 2a studies
    • Wenzel, S., Wilbraham, D., Fuller, R., Getz, E.B. & Longphre, M. Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: Results of two phase 2a studies Lancet 370, 1422-1431 (2007).
    • (2007) Lancet , vol.370 , pp. 1422-1431
    • Wenzel, S.1    Wilbraham, D.2    Fuller, R.3    Getz, E.B.4    Longphre, M.5
  • 16
    • 6644229440 scopus 로고    scopus 로고
    • Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
    • Leckie, M.J. et al. Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 356, 2144-2148 (2000).
    • (2000) Lancet , vol.356 , pp. 2144-2148
    • Leckie, M.J.1
  • 17
    • 0031042155 scopus 로고    scopus 로고
    • Allergic rhinitis and asthma: How important is the link?
    • Corren, J. Allergic rhinitis and asthma: How important is the link? J. Allergy Clin. Immunol. 99, S781-S786 (1997).
    • (1997) J. Allergy Clin. Immunol , vol.99
    • Corren, J.1
  • 18
    • 12744262855 scopus 로고    scopus 로고
    • Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma
    • Cho, S.H., Stanciu, L.A., Holgate, S.T. & Johnston, S.L. Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma. Am. J. Respir. Crit. Care Med. 171, 224-230 (2005).
    • (2005) Am. J. Respir. Crit. Care Med , vol.171 , pp. 224-230
    • Cho, S.H.1    Stanciu, L.A.2    Holgate, S.T.3    Johnston, S.L.4
  • 19
    • 0035090628 scopus 로고    scopus 로고
    • Association of IFN-gamma and IFN regulatory factor 1 polymorphisms with childhood atopic asthma
    • Nakao, F. et al. Association of IFN-gamma and IFN regulatory factor 1 polymorphisms with childhood atopic asthma. J. Allergy Clin. Immunol. 107, 499-504 (2001).
    • (2001) J. Allergy Clin. Immunol , vol.107 , pp. 499-504
    • Nakao, F.1
  • 20
    • 33751180809 scopus 로고    scopus 로고
    • IL-17 mRNA in sputum of asthmatic patients: Linking T cell driven inflammation and granulocytic influx?
    • Bullens, D.M. et al. IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir. Res. 7, 135 (2006).
    • (2006) Respir. Res , vol.7 , pp. 135
    • Bullens, D.M.1
  • 22
    • 39549106479 scopus 로고    scopus 로고
    • Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17
    • Pichavant, M. et al. Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17. J. Exp. Med. 205, 385-393 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 385-393
    • Pichavant, M.1
  • 23
    • 34247485053 scopus 로고    scopus 로고
    • Noneosinophilic asthma: A distinct clinical and pathologic phenotype
    • quiz 1053-1054
    • Haldar, P. & Pavord, I.D. Noneosinophilic asthma: A distinct clinical and pathologic phenotype. J. Allergy Clin. Immunol. 119, 1043-1052; quiz 1053-1054 (2007).
    • (2007) J. Allergy Clin. Immunol , vol.119 , pp. 1043-1052
    • Haldar, P.1    Pavord, I.D.2
  • 24
    • 0024840168 scopus 로고
    • Inflammatory cells in bronchial asthma
    • Kay, A.B. Inflammatory cells in bronchial asthma. J. Asthma 26 335-344 (1989).
    • (1989) J. Asthma , vol.26 , pp. 335-344
    • Kay, A.B.1
  • 26
    • 34249912039 scopus 로고    scopus 로고
    • Severe asthma in adults: What are the important questions?
    • Chanez, P. et al. Severe asthma in adults: What are the important questions? J. Allergy Clin. Immunol. 119, 1337-1348 (2007).
    • (2007) J. Allergy Clin. Immunol , vol.119 , pp. 1337-1348
    • Chanez, P.1
  • 27
    • 0036795111 scopus 로고    scopus 로고
    • Analysis of induced sputum in adults with asthma: Identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids
    • Green, R.H., Brightling, C.E., Woltmann, G., Parker, D., Wardlaw, A.J. & Pavord, I.D. Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax 57, 875-879 (2002).
    • (2002) Thorax , vol.57 , pp. 875-879
    • Green, R.H.1    Brightling, C.E.2    Woltmann, G.3    Parker, D.4    Wardlaw, A.J.5    Pavord, I.D.6
  • 28
    • 62749086297 scopus 로고    scopus 로고
    • Functional CD1d and/or NKT cell invariant chain transcript in horse, pig, African elephant and guinea pig, but not in ruminants
    • Looringh van Beeck, F.A. et al. Functional CD1d and/or NKT cell invariant chain transcript in horse, pig, African elephant and guinea pig, but not in ruminants. Mol. Immunol. 46, 1424-1431 (2009).
    • (2009) Mol. Immunol , vol.46 , pp. 1424-1431
    • Looringh van Beeck, F.A.1
  • 29
    • 33645772964 scopus 로고    scopus 로고
    • The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d
    • Van Rhijn, I. et al. The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d. J. Immunol. 176, 4888-4893 (2006).
    • (2006) J. Immunol , vol.176 , pp. 4888-4893
    • Van Rhijn, I.1
  • 30
    • 0030696696 scopus 로고    scopus 로고
    • CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides
    • Kawano, T. et al. CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science 278, 1626-1629 (1997).
    • (1997) Science , vol.278 , pp. 1626-1629
    • Kawano, T.1
  • 31
    • 85185122826 scopus 로고    scopus 로고
    • Spada, F.M., Koezuka, Y. & Porcelli, S.A. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells. J. Exp. Med. 188, 1529-1534 (1998).
    • Spada, F.M., Koezuka, Y. & Porcelli, S.A. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells. J. Exp. Med. 188, 1529-1534 (1998).
  • 32
    • 34548745246 scopus 로고    scopus 로고
    • Germline-encoded recognition of diverse glycolipids by natural killer T cells
    • Scott-Browne, J.P. et al. Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nat. Immunol. 8, 1105-1113 (2007).
    • (2007) Nat. Immunol , vol.8 , pp. 1105-1113
    • Scott-Browne, J.P.1
  • 34
    • 0034353121 scopus 로고    scopus 로고
    • Recognition and function of Valpha14 NKT cells
    • Taniguchi, M. & Nakayama, T. Recognition and function of Valpha14 NKT cells. Semin. Immunol. 12, 543-550 (2000).
    • (2000) Semin. Immunol , vol.12 , pp. 543-550
    • Taniguchi, M.1    Nakayama, T.2
  • 35
    • 0032698211 scopus 로고    scopus 로고
    • Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells
    • Kawano, T. et al. Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells. Cancer Res. 59, 5102-5105 (1999).
    • (1999) Cancer Res , vol.59 , pp. 5102-5105
    • Kawano, T.1
  • 36
    • 0035884974 scopus 로고    scopus 로고
    • Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells
    • Metelitsa, L.S. et al. Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells. J. Immunol. 167, 3114-3122 (2001).
    • (2001) J. Immunol , vol.167 , pp. 3114-3122
    • Metelitsa, L.S.1
  • 37
    • 29444439664 scopus 로고    scopus 로고
    • Valpha14i NKT cells are innate lymphocytes that participate in the immune response to diverse microbes
    • Kinjo, Y. & Kronenberg, M. Valpha14i NKT cells are innate lymphocytes that participate in the immune response to diverse microbes. J. Clin. Immunol. 25, 522-533 (2005).
    • (2005) J. Clin. Immunol , vol.25 , pp. 522-533
    • Kinjo, Y.1    Kronenberg, M.2
  • 38
    • 0141446179 scopus 로고    scopus 로고
    • Role of CD1d-restricted NKT cells in microbial immunity
    • Skold, M. & Behar, S.M. Role of CD1d-restricted NKT cells in microbial immunity. Infect. Immun. 71, 5447-5455 (2003).
    • (2003) Infect. Immun , vol.71 , pp. 5447-5455
    • Skold, M.1    Behar, S.M.2
  • 39
    • 56849090964 scopus 로고    scopus 로고
    • The role of NKT cells in tumor immunity
    • Terabe, M. & Berzofsky, J.A. The role of NKT cells in tumor immunity. Adv. Cancer Res. 101, 277-348 (2008).
    • (2008) Adv. Cancer Res , vol.101 , pp. 277-348
    • Terabe, M.1    Berzofsky, J.A.2
  • 40
    • 42649142005 scopus 로고    scopus 로고
    • Immune regulation by invariant NKT cells in autoimmunity
    • Ronchi, F. & Falcone, M. Immune regulation by invariant NKT cells in autoimmunity. Front. Biosci. 13, 4827-4837 (2008).
    • (2008) Front. Biosci , vol.13 , pp. 4827-4837
    • Ronchi, F.1    Falcone, M.2
  • 41
    • 0035956942 scopus 로고    scopus 로고
    • Requirement for natural killer T (NKT) cells in the induction of allograft tolerance
    • Seino, K.I. et al. Requirement for natural killer T (NKT) cells in the induction of allograft tolerance. Proc. Natl. Acad. Sci. USA 98, 2577-2581 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2577-2581
    • Seino, K.I.1
  • 42
    • 1342321659 scopus 로고    scopus 로고
    • CD1d-dependent activation of NKT cells aggravates atherosclerosis
    • Tupin, E. et al. CD1d-dependent activation of NKT cells aggravates atherosclerosis. J. Exp. Med. 199, 417-422 (2004).
    • (2004) J. Exp. Med , vol.199 , pp. 417-422
    • Tupin, E.1
  • 43
    • 33845211133 scopus 로고    scopus 로고
    • A role for natural killer T cells in asthma
    • Umetsu, D.T. & DeKruyff, R.H. A role for natural killer T cells in asthma. Nat. Rev. Immunol. 6, 953-958 (2006).
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 953-958
    • Umetsu, D.T.1    DeKruyff, R.H.2
  • 44
    • 0037911660 scopus 로고    scopus 로고
    • Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
    • Akbari, O. et al. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat. Med. 9, 582-588 (2003).
    • (2003) Nat. Med , vol.9 , pp. 582-588
    • Akbari, O.1
  • 45
    • 0042090563 scopus 로고    scopus 로고
    • Cutting edge: Invariant V alpha 14 NKT cells are required for allergen-induced airway inflammation and hyperreactivity in an experimental asthma model
    • Lisbonne, M. et al. Cutting edge: Invariant V alpha 14 NKT cells are required for allergen-induced airway inflammation and hyperreactivity in an experimental asthma model. J. Immunol. 171, 1637-1641 (2003).
    • (2003) J. Immunol , vol.171 , pp. 1637-1641
    • Lisbonne, M.1
  • 46
    • 85185097919 scopus 로고    scopus 로고
    • Natural killer T cells and CD8+ T cells are dispensable for T cell-dependent allergic airway inflammation, author reply 7
    • Das, J. et al. Natural killer T cells and CD8+ T cells are dispensable for T cell-dependent allergic airway inflammation. Nat. Med. 12, 1345-1346; author reply 7 (2006).
    • (2006) Nat. Med , vol.12 , pp. 1345-1346
    • Das, J.1
  • 47
    • 0033081761 scopus 로고    scopus 로고
    • Natural killer cells determine development of allergen-induced eosinophilic airway inflammation in mice
    • Korsgren, M. et al. Natural killer cells determine development of allergen-induced eosinophilic airway inflammation in mice. J. Exp. Med. 189, 553-562 (1999).
    • (1999) J. Exp. Med , vol.189 , pp. 553-562
    • Korsgren, M.1
  • 48
    • 1642288509 scopus 로고    scopus 로고
    • Natural killer T cells contribute to airway eosinophilic inflammation induced by ragweed through enhanced IL-4 and eotaxin production
    • Bilenki, L., Yang, J., Fan, Y., Wang, S. & Yang, X. Natural killer T cells contribute to airway eosinophilic inflammation induced by ragweed through enhanced IL-4 and eotaxin production. Eur. J. Immunol. 34, 345-354 (2004).
    • (2004) Eur. J. Immunol , vol.34 , pp. 345-354
    • Bilenki, L.1    Yang, J.2    Fan, Y.3    Wang, S.4    Yang, X.5
  • 49
    • 0031028170 scopus 로고    scopus 로고
    • Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells
    • Smiley, S.T., Kaplan, M.H. & Grusby, M.J. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells. Science 275, 977-979 (1997).
    • (1997) Science , vol.275 , pp. 977-979
    • Smiley, S.T.1    Kaplan, M.H.2    Grusby, M.J.3
  • 50
    • 0027331625 scopus 로고
    • Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy
    • Aris, R.M., Christian, D., Hearne, P. Q., Kerr, K., Finkbeiner, W.E. & Balmes, JR. Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy. Am. Rev. Respir. Dis. 148, 1363-1372 (1993).
    • (1993) Am. Rev. Respir. Dis , vol.148 , pp. 1363-1372
    • Aris, R.M.1    Christian, D.2    Hearne, P.Q.3    Kerr, K.4    Finkbeiner, W.E.5    Balmes, J.R.6
  • 51
    • 0141957222 scopus 로고    scopus 로고
    • Association of low-level ozone and fine particles with respiratory symptoms in children with asthma
    • Gent, J.F. et al. Association of low-level ozone and fine particles with respiratory symptoms in children with asthma. JAMA 290, 1859-1867 (2003).
    • (2003) JAMA , vol.290 , pp. 1859-1867
    • Gent, J.F.1
  • 52
    • 42649110747 scopus 로고    scopus 로고
    • Cutting edge: NKT cells constitutively express IL-23 receptor and RORgammat and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion
    • Rachitskaya, A.V. et al. Cutting edge: NKT cells constitutively express IL-23 receptor and RORgammat and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion. J. Immunol. 180, 5167-5171 (2008).
    • (2008) J. Immunol , vol.180 , pp. 5167-5171
    • Rachitskaya, A.V.1
  • 53
    • 34249059942 scopus 로고    scopus 로고
    • Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia
    • Michel, M.L. et al. Identification of an IL-17-producing NK1.1(neg) iNKT cell population involved in airway neutrophilia. J. Exp. Med. 204, 995-1001 (2007).
    • (2007) J. Exp. Med , vol.204 , pp. 995-1001
    • Michel, M.L.1
  • 54
    • 44549084970 scopus 로고    scopus 로고
    • A distinct subset of natural killer T cells produces IL-17, contributing to airway infiltration of neutrophils but not to airway hyperreactivity
    • Lee, K.A. et al. A distinct subset of natural killer T cells produces IL-17, contributing to airway infiltration of neutrophils but not to airway hyperreactivity. Cell Immunol. 251, 50-55 (2008).
    • (2008) Cell Immunol , vol.251 , pp. 50-55
    • Lee, K.A.1
  • 55
    • 49649123906 scopus 로고    scopus 로고
    • Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4 - NK1.1 - NKT cell population
    • Coquet, J.M. et al. Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4 - NK1.1 - NKT cell population. Proc. Natl. Acad. Sci. USA 105, 11287-11292 (2008).
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 11287-11292
    • Coquet, J.M.1
  • 56
    • 57249096982 scopus 로고    scopus 로고
    • Murine NKT cells produce Th17 cytokine interleukin-22
    • Goto, M. et al. Murine NKT cells produce Th17 cytokine interleukin-22. Cell Immunol. 254, 81-84 (2009).
    • (2009) Cell Immunol , vol.254 , pp. 81-84
    • Goto, M.1
  • 57
    • 0033836306 scopus 로고    scopus 로고
    • The role of viral infections in the natural history of asthma
    • Gern, J.E. & Busse, W.W. The role of viral infections in the natural history of asthma. J. Allergy Clin. Immunol. 106, 201-212 (2000).
    • (2000) J. Allergy Clin. Immunol , vol.106 , pp. 201-212
    • Gern, J.E.1    Busse, W.W.2
  • 58
    • 12144272208 scopus 로고    scopus 로고
    • Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13
    • Sigurs, N. et al. Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am. J. Respir. Crit. Care Med. 171, 137-141 (2005).
    • (2005) Am. J. Respir. Crit. Care Med , vol.171 , pp. 137-141
    • Sigurs, N.1
  • 59
    • 33744820545 scopus 로고    scopus 로고
    • Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice
    • Hamelin, M.E., Prince, G.A., Gomez, A. M., Kinkead, R. & Boivin, G. Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice. J. Infect. Dis. 193, 1634-1642 (2006).
    • (2006) J. Infect. Dis , vol.193 , pp. 1634-1642
    • Hamelin, M.E.1    Prince, G.A.2    Gomez, A.M.3    Kinkead, R.4    Boivin, G.5
  • 60
    • 44949257271 scopus 로고    scopus 로고
    • Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease
    • Kim, E.Y. et al. Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease. Nat. Med. 14, 633-640 (2008).
    • (2008) Nat. Med , vol.14 , pp. 633-640
    • Kim, E.Y.1
  • 61
    • 0029959243 scopus 로고    scopus 로고
    • Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses
    • Brown, D.R. et al. Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses. J. Exp. Med. 184, 1295-1304 (1996).
    • (1996) J. Exp. Med , vol.184 , pp. 1295-1304
    • Brown, D.R.1
  • 62
    • 0029854521 scopus 로고    scopus 로고
    • Beta 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses
    • Zhang, Y., Rogers, K.H. & Lewis, D.B. Beta 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses. J. Exp. Med. 184, 1507-1512 (1996).
    • (1996) J. Exp. Med , vol.184 , pp. 1507-1512
    • Zhang, Y.1    Rogers, K.H.2    Lewis, D.B.3
  • 63
    • 0032529211 scopus 로고    scopus 로고
    • CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: Beta 2-microglobulin-dependent and independent forms
    • Amano, M. et al. CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: Beta 2-microglobulin-dependent and independent forms. J. Immunol. 161, 1710-1717 (1998).
    • (1998) J. Immunol , vol.161 , pp. 1710-1717
    • Amano, M.1
  • 64
    • 0028170270 scopus 로고
    • Beta 2-microglobulin-independent MHC class Ib molecule expressed by human intestinal epithelium
    • Balk, S.P. et al. Beta 2-microglobulin-independent MHC class Ib molecule expressed by human intestinal epithelium. Science 265 259-262 (1994).
    • (1994) Science , vol.265 , pp. 259-262
    • Balk, S.P.1
  • 65
    • 0000901959 scopus 로고    scopus 로고
    • Biochemical characterization of CD1d expression in the absence of beta2-microglobulin
    • Kim, H.S., Garcia, J., Exley, M., Johnson, K. W., Balk, S.P. & Blumberg, R.S. Biochemical characterization of CD1d expression in the absence of beta2-microglobulin. J. Biol. Chem. 274, 9289-9295 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 9289-9295
    • Kim, H.S.1    Garcia, J.2    Exley, M.3    Johnson, K.W.4    Balk, S.P.5    Blumberg, R.S.6
  • 66
    • 33845978450 scopus 로고    scopus 로고
    • An N-linked glycan modulates the interaction between the CD1d heavy chain and beta 2-microglobulin
    • Paduraru, C. et al. An N-linked glycan modulates the interaction between the CD1d heavy chain and beta 2-microglobulin. J. Biol. Chem. 281, 40369-40378 (2006).
    • (2006) J. Biol. Chem , vol.281 , pp. 40369-40378
    • Paduraru, C.1
  • 67
    • 85185099955 scopus 로고    scopus 로고
    • Maeda, M., Shadeo, A., MacFadyen, A.M. & Takei, F. CD1d-independent NKT cells in beta 2-microglobulin-deficient mice have hybrid phenotype and function of NK and T cells. J. Immunol. 172, 6115-6122 (2004).
    • Maeda, M., Shadeo, A., MacFadyen, A.M. & Takei, F. CD1d-independent NKT cells in beta 2-microglobulin-deficient mice have hybrid phenotype and function of NK and T cells. J. Immunol. 172, 6115-6122 (2004).
  • 68
    • 58149314590 scopus 로고    scopus 로고
    • Activation of nonclassical CD1d-restricted NK T cells induces airway hyperreactivity in beta 2-microglobulin-deficient mice
    • Koh, Y.I. et al. Activation of nonclassical CD1d-restricted NK T cells induces airway hyperreactivity in beta 2-microglobulin-deficient mice. J. Immunol. 181, 4560-4569 (2008).
    • (2008) J. Immunol , vol.181 , pp. 4560-4569
    • Koh, Y.I.1
  • 69
    • 0037059509 scopus 로고    scopus 로고
    • Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet
    • Finotto, S. et al. Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet. Science 295 336-338 (2002).
    • (2002) Science , vol.295 , pp. 336-338
    • Finotto, S.1
  • 71
    • 0037059462 scopus 로고    scopus 로고
    • Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells
    • Szabo, S.J., Sullivan, B.M., Stemmann, C., Satoskar, A. R., Sleckman, B.P. & Glimcher, L.H. Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells. Science 295, 338-342 (2002).
    • (2002) Science , vol.295 , pp. 338-342
    • Szabo, S.J.1    Sullivan, B.M.2    Stemmann, C.3    Satoskar, A.R.4    Sleckman, B.P.5    Glimcher, L.H.6
  • 72
    • 1842785209 scopus 로고    scopus 로고
    • T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells
    • Townsend, M.J. et al. T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity 20, 477-494 (2004).
    • (2004) Immunity , vol.20 , pp. 477-494
    • Townsend, M.J.1
  • 73
    • 64849101129 scopus 로고    scopus 로고
    • The development of airway hyperreactivity in T-bet-deficient mice requires CD1d-restricted NKT cells
    • Kim, H.Y. et al. The development of airway hyperreactivity in T-bet-deficient mice requires CD1d-restricted NKT cells. J. Immunol. 182, 3252-3261 (2009).
    • (2009) J. Immunol , vol.182 , pp. 3252-3261
    • Kim, H.Y.1
  • 74
    • 33644986351 scopus 로고    scopus 로고
    • CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma
    • Akbari, O. et al. CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma. N. Engl. J. Med. 354, 1117-1129 (2006).
    • (2006) N. Engl. J. Med , vol.354 , pp. 1117-1129
    • Akbari, O.1
  • 75
    • 26844537217 scopus 로고    scopus 로고
    • V alpha 24-invariant NKT cells from patients with allergic asthma express CCR9 at high frequency and induce Th2 bias of CD3+ T cells upon CD226 engagement
    • Sen, Y. et al. V alpha 24-invariant NKT cells from patients with allergic asthma express CCR9 at high frequency and induce Th2 bias of CD3+ T cells upon CD226 engagement. J. Immunol. 175, 4914-4926 (2005).
    • (2005) J. Immunol , vol.175 , pp. 4914-4926
    • Sen, Y.1
  • 77
    • 33645549265 scopus 로고    scopus 로고
    • NKT cells in the induced sputum of severe asthmatics
    • Hamzaoui, A. et al. NKT cells in the induced sputum of severe asthmatics. Mediators Inflamm. 2006, 71214 (2006).
    • (2006) Mediators Inflamm , vol.2006 , pp. 71214
    • Hamzaoui, A.1
  • 78
    • 35748979975 scopus 로고    scopus 로고
    • Detection of natural killer T cells in the sinus mucosa from asthmatics with chronic sinusitis
    • Yamamoto, H., Okamoto, Y., Horiguchi, S., Kunii, N., Yonekura, S. & Nakayama, T. Detection of natural killer T cells in the sinus mucosa from asthmatics with chronic sinusitis. Allergy 62, 1451-1455 (2007).
    • (2007) Allergy , vol.62 , pp. 1451-1455
    • Yamamoto, H.1    Okamoto, Y.2    Horiguchi, S.3    Kunii, N.4    Yonekura, S.5    Nakayama, T.6
  • 79
    • 53849121626 scopus 로고    scopus 로고
    • Complementary roles for lipid and protein allergens in triggering innate and adaptive immune systems
    • Russano, A.M., Agea, E., Casciari, C., de Benedictis, F.M. & Spinozzi, F. Complementary roles for lipid and protein allergens in triggering innate and adaptive immune systems. Allergy 63, 1428-1437 (2008).
    • (2008) Allergy , vol.63 , pp. 1428-1437
    • Russano, A.M.1    Agea, E.2    Casciari, C.3    de Benedictis, F.M.4    Spinozzi, F.5
  • 80
    • 85185109639 scopus 로고    scopus 로고
    • Fujiki, R., Yokoyama, T., Watson, R., Gauvreau, G. & O'Byrne, P. NKT cells in sputum and peripheral blood from subjects with allergen-induced late asthmatic responses. J. Resp. Crit. Care Med. 2007; ATS abstracts: A680 (2007).
    • Fujiki, R., Yokoyama, T., Watson, R., Gauvreau, G. & O'Byrne, P. NKT cells in sputum and peripheral blood from subjects with allergen-induced late asthmatic responses. J. Resp. Crit. Care Med. 2007; ATS abstracts: A680 (2007).
  • 81
    • 67349188780 scopus 로고    scopus 로고
    • Natural killer T cells in the lungs of patients with asthma
    • Matangkasombut, P. et al. Natural killer T cells in the lungs of patients with asthma. J. Allergy Clin. Immunol. (2009).
    • (2009) J. Allergy Clin. Immunol
    • Matangkasombut, P.1
  • 82
    • 34247468102 scopus 로고    scopus 로고
    • Bronchoalveolar lavage invariant natural killer T cells are not increased in asthma
    • Mutalithas, K. et al. Bronchoalveolar lavage invariant natural killer T cells are not increased in asthma. J. Allergy Clin. Immunol. 119, 1274-1276 (2007).
    • (2007) J. Allergy Clin. Immunol , vol.119 , pp. 1274-1276
    • Mutalithas, K.1
  • 83
    • 34047261246 scopus 로고    scopus 로고
    • Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease
    • Vijayanand, P. et al. Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease. N. Engl. J. Med. 356 1410-1422 (2007).
    • (2007) N. Engl. J. Med , vol.356 , pp. 1410-1422
    • Vijayanand, P.1
  • 84
    • 85185143302 scopus 로고    scopus 로고
    • Thomas, S.Y., Lilly, C.M. & Luster, A.D. Invariant natural killer T cells in bronchial asthma. N. Engl. J. Med. 354, 2613-2616; author reply: 2613-2616 (2006).
    • Thomas, S.Y., Lilly, C.M. & Luster, A.D. Invariant natural killer T cells in bronchial asthma. N. Engl. J. Med. 354, 2613-2616; author reply: 2613-2616 (2006).
  • 85
    • 85185130084 scopus 로고    scopus 로고
    • Bratke, K., Julius, P. & Virchow, J.C. Invariant natural killer T cells in obstructive pulmonary diseases. N. Engl. J. Med. 357, 194; author reply: 194-145 (2007).
    • Bratke, K., Julius, P. & Virchow, J.C. Invariant natural killer T cells in obstructive pulmonary diseases. N. Engl. J. Med. 357, 194; author reply: 194-145 (2007).
  • 86
    • 50549092067 scopus 로고    scopus 로고
    • Increased cytotoxicity of CD4+ invariant NKT cells against CD4+CD25hiCD127lo/-regulatory T cells in allergic asthma
    • Nguyen, K.D., Vanichsarn, C. & Nadeau, K.C. Increased cytotoxicity of CD4+ invariant NKT cells against CD4+CD25hiCD127lo/-regulatory T cells in allergic asthma. Eur. J. Immunol. 38, 2034-2045 (2008).
    • (2008) Eur. J. Immunol , vol.38 , pp. 2034-2045
    • Nguyen, K.D.1    Vanichsarn, C.2    Nadeau, K.C.3
  • 87
    • 43049088082 scopus 로고    scopus 로고
    • Direct activation of natural killer T cells induces airway hyperreactivity in nonhuman primates
    • Matangkasombut, P. et al. Direct activation of natural killer T cells induces airway hyperreactivity in nonhuman primates. J. Allergy Clin. Immunol. 121, 1287-1289 (2008).
    • (2008) J. Allergy Clin. Immunol , vol.121 , pp. 1287-1289
    • Matangkasombut, P.1
  • 88
    • 22344434436 scopus 로고    scopus 로고
    • Nonhuman primate models of asthma
    • Coffman, R.L. & Hessel, E.M. Nonhuman primate models of asthma. J. Exp. Med. 201, 1875-1879 (2005).
    • (2005) J. Exp. Med , vol.201 , pp. 1875-1879
    • Coffman, R.L.1    Hessel, E.M.2
  • 89
    • 42149167724 scopus 로고    scopus 로고
    • iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity
    • Meyer, E.H. et al. iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity. J. Immunol. 179 4661-4671 (2007).
    • (2007) J. Immunol , vol.179 , pp. 4661-4671
    • Meyer, E.H.1
  • 90
    • 10044280324 scopus 로고    scopus 로고
    • Lysosomal glycosphingolipid recognition by NKT cells
    • Zhou, D. et al. Lysosomal glycosphingolipid recognition by NKT cells. Science 306, 1786-1789 (2004).
    • (2004) Science , vol.306 , pp. 1786-1789
    • Zhou, D.1
  • 91
    • 23244459501 scopus 로고    scopus 로고
    • Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: A molecular basis for NKT cell activation
    • Giabbai, B. et al. Crystal structure of mouse CD1d bound to the self ligand phosphatidylcholine: A molecular basis for NKT cell activation. J. Immunol. 175, 977-984 (2005).
    • (2005) J. Immunol , vol.175 , pp. 977-984
    • Giabbai, B.1
  • 92
    • 0034143918 scopus 로고    scopus 로고
    • Murine CD1d-restricted T cell recognition of cellular lipids
    • Gumperz, J.E. et al. Murine CD1d-restricted T cell recognition of cellular lipids. Immunity 12, 211-221 (2000).
    • (2000) Immunity , vol.12 , pp. 211-221
    • Gumperz, J.E.1
  • 93
    • 10744227951 scopus 로고    scopus 로고
    • Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cell
    • Rauch, J. et al. Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cell. J. Biol. Chem. 278, 47508-47515 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 47508-47515
    • Rauch, J.1
  • 94
    • 0038152830 scopus 로고    scopus 로고
    • Cross-presentation of disialoganglioside GD3 to natural killer T cells
    • Wu, D.Y., Segal, N.H., Sidobre, S., Kronenberg, M. & Chapman, P.B. Cross-presentation of disialoganglioside GD3 to natural killer T cells. J. Exp. Med. 198, 173-181 (2003).
    • (2003) J. Exp. Med , vol.198 , pp. 173-181
    • Wu, D.Y.1    Segal, N.H.2    Sidobre, S.3    Kronenberg, M.4    Chapman, P.B.5
  • 95
    • 23944448650 scopus 로고    scopus 로고
    • Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor
    • Zajonc, D.M. et al. Structure and function of a potent agonist for the semi-invariant natural killer T cell receptor. Nat. Immunol. 6, 810-818 (2005).
    • (2005) Nat. Immunol , vol.6 , pp. 810-818
    • Zajonc, D.M.1
  • 96
    • 33644504477 scopus 로고    scopus 로고
    • Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells
    • Meyer, E.H. et al. Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells. Proc. Natl. Acad. Sci. USA 103, 2782-2787 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2782-2787
    • Meyer, E.H.1
  • 97
    • 15844421595 scopus 로고    scopus 로고
    • Recognition of bacterial glycosphingolipids by natural killer T cells
    • Kinjo, Y. et al. Recognition of bacterial glycosphingolipids by natural killer T cells. Nature 434, 520-525 (2005).
    • (2005) Nature , vol.434 , pp. 520-525
    • Kinjo, Y.1
  • 98
    • 20144389877 scopus 로고    scopus 로고
    • Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
    • Mattner, J. et al. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 434, 525-529 (2005).
    • (2005) Nature , vol.434 , pp. 525-529
    • Mattner, J.1
  • 99
    • 33747226069 scopus 로고    scopus 로고
    • Glycolipids and phospholipids as natural CD1d-binding NKT cell ligands
    • Tsuji, M. Glycolipids and phospholipids as natural CD1d-binding NKT cell ligands. Cell. Mol. Life Sci. 63, 1889-1898 (2006).
    • (2006) Cell. Mol. Life Sci , vol.63 , pp. 1889-1898
    • Tsuji, M.1
  • 100
    • 33747607029 scopus 로고    scopus 로고
    • Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria
    • Kinjo, Y. et al. Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat. Immunol. 7, 978-986 (2006).
    • (2006) Nat. Immunol , vol.7 , pp. 978-986
    • Kinjo, Y.1
  • 101
    • 3242709268 scopus 로고    scopus 로고
    • Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells
    • Fischer, K. et al. Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells. Proc. Natl. Acad. Sci. USA 101, 10685-10690 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 10685-10690
    • Fischer, K.1
  • 102
    • 0035860824 scopus 로고    scopus 로고
    • Acylation state of the phosphatidylinositol mannosides from Mycobacterium bovis bacillus Calmette Guerin and ability to induce granuloma and recruit natural killer T cells
    • Gilleron, M., Ronet, C., Mempel, M., Monsarrat, B., Gachelin, G. & Puzo, G. Acylation state of the phosphatidylinositol mannosides from Mycobacterium bovis bacillus Calmette Guerin and ability to induce granuloma and recruit natural killer T cells. J. Biol. Chem. 276, 34896-34904 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 34896-34904
    • Gilleron, M.1    Ronet, C.2    Mempel, M.3    Monsarrat, B.4    Gachelin, G.5    Puzo, G.6
  • 103
    • 5444259450 scopus 로고    scopus 로고
    • A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan
    • Amprey, J.L. et al. A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan. J. Exp. Med. 200, 895-904 (2004).
    • (2004) J. Exp. Med , vol.200 , pp. 895-904
    • Amprey, J.L.1
  • 104
    • 0347776209 scopus 로고    scopus 로고
    • Mechanism of CD1d-restricted natural killer T cell activation during microbial infection
    • Brigl, M., Bry, L., Kent, S.C., Gumperz, J.E. & Brenner, M.B. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat. Immunol. 4, 1230-1237 (2003).
    • (2003) Nat. Immunol , vol.4 , pp. 1230-1237
    • Brigl, M.1    Bry, L.2    Kent, S.C.3    Gumperz, J.E.4    Brenner, M.B.5
  • 105
    • 35448936431 scopus 로고    scopus 로고
    • Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids
    • Paget, C. et al. Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids. Immunity 27, 597-609 (2007).
    • (2007) Immunity , vol.27 , pp. 597-609
    • Paget, C.1
  • 106
    • 45749092102 scopus 로고    scopus 로고
    • Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice
    • Kim, S., Lalani, S., Parekh, V.V., Vincent, T.L., Wu, L. & Van Kaer, L. Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice. J. Clin. Invest. 118 2301-2315 (2008).
    • (2008) J. Clin. Invest , vol.118 , pp. 2301-2315
    • Kim, S.1    Lalani, S.2    Parekh, V.V.3    Vincent, T.L.4    Wu, L.5    Van Kaer, L.6
  • 107
    • 58149277749 scopus 로고    scopus 로고
    • Cutting edge: The mechanism of invariant NKT cell responses to viral danger signals
    • Tyznik, A.J., Tupin, E., Nagarajan, N.A., Her, M.J., Benedict, C.A. & Kronenberg, M. Cutting edge: The mechanism of invariant NKT cell responses to viral danger signals. J. Immunol. 181, 4452-4456 (2008).
    • (2008) J. Immunol , vol.181 , pp. 4452-4456
    • Tyznik, A.J.1    Tupin, E.2    Nagarajan, N.A.3    Her, M.J.4    Benedict, C.A.5    Kronenberg, M.6
  • 108
    • 33847361128 scopus 로고    scopus 로고
    • Invariant NKT cells amplify the innate immune response to lipopolysaccharide
    • Nagarajan, N.A. & Kronenberg, M. Invariant NKT cells amplify the innate immune response to lipopolysaccharide. J. Immunol. 178, 2706-2713 (2007).
    • (2007) J. Immunol , vol.178 , pp. 2706-2713
    • Nagarajan, N.A.1    Kronenberg, M.2
  • 109
    • 22944439737 scopus 로고    scopus 로고
    • Human CD1-restricted T cell recognition of lipids from pollens
    • Agea, E. et al. Human CD1-restricted T cell recognition of lipids from pollens. J. Exp. Med. 202, 295-308 (2005).
    • (2005) J. Exp. Med , vol.202 , pp. 295-308
    • Agea, E.1
  • 110
    • 33644751206 scopus 로고    scopus 로고
    • IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts
    • Letuve, S. et al. IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts. J. Allergy Clin. Immunol. 117, 590-596 (2006).
    • (2006) J. Allergy Clin. Immunol , vol.117 , pp. 590-596
    • Letuve, S.1
  • 111
    • 33645896155 scopus 로고    scopus 로고
    • Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract
    • Owyang, A.M. et al. Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. J. Exp. Med. 203, 843-849 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 843-849
    • Owyang, A.M.1
  • 112
    • 18244405108 scopus 로고    scopus 로고
    • IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo
    • Fort, M.M. et al. IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity 15, 985-995 (2001).
    • (2001) Immunity , vol.15 , pp. 985-995
    • Fort, M.M.1
  • 113
    • 34447281733 scopus 로고    scopus 로고
    • Interleukin 25 promotes the initiation of proallergic type 2 responses
    • Angkasekwinai, P. et al. Interleukin 25 promotes the initiation of proallergic type 2 responses. J. Exp. Med. 204, 1509-1517 (2007).
    • (2007) J. Exp. Med , vol.204 , pp. 1509-1517
    • Angkasekwinai, P.1
  • 114
    • 33748064320 scopus 로고    scopus 로고
    • IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice
    • Tamachi, T. et al. IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice. J. Allergy Clin. Immunol. 118, 606-614 (2006).
    • (2006) J. Allergy Clin. Immunol , vol.118 , pp. 606-614
    • Tamachi, T.1
  • 115
    • 36749051929 scopus 로고    scopus 로고
    • Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma
    • Ballantyne, S.J. et al. Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma. J. Allergy Clin. Immunol. 120, 1324-1331 (2007).
    • (2007) J. Allergy Clin. Immunol , vol.120 , pp. 1324-1331
    • Ballantyne, S.J.1
  • 116
    • 58149289887 scopus 로고    scopus 로고
    • A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity
    • Terashima, A. et al. A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity. J. Exp. Med. 205, 2727-2733 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 2727-2733
    • Terashima, A.1
  • 117
    • 65249164230 scopus 로고    scopus 로고
    • Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB
    • Stock, P., Lombardi, V., Kohlrautz, V. & Akbari, O. Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB. J. Immunol. 182, 5116-5122 (2009).
    • (2009) J. Immunol , vol.182 , pp. 5116-5122
    • Stock, P.1    Lombardi, V.2    Kohlrautz, V.3    Akbari, O.4
  • 118
    • 27744446058 scopus 로고    scopus 로고
    • IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
    • Schmitz, J. et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23, 479-490 (2005).
    • (2005) Immunity , vol.23 , pp. 479-490
    • Schmitz, J.1
  • 119
    • 0037631696 scopus 로고    scopus 로고
    • Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules
    • Baekkevold, E.S. et al. Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules. Am. J. Pathol. 163, 69-79 (2003).
    • (2003) Am. J. Pathol , vol.163 , pp. 69-79
    • Baekkevold, E.S.1
  • 120
    • 44849117539 scopus 로고    scopus 로고
    • Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
    • Kondo, Y. et al. Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int. Immunol. 20, 791-800 (2008).
    • (2008) Int. Immunol , vol.20 , pp. 791-800
    • Kondo, Y.1
  • 121
    • 65449146468 scopus 로고    scopus 로고
    • The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production
    • Bourgeois, E. et al. The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production. Eur. J. Immunol. 39, 1046-1055 (2009).
    • (2009) Eur. J. Immunol , vol.39 , pp. 1046-1055
    • Bourgeois, E.1
  • 122
    • 85185105863 scopus 로고    scopus 로고
    • Smithgall, M.D., Comeau, M.R., Yoon, B.R., Kaufman, D., Armitage, R. & Smith, D.E. IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells. Int. Immunol. 20, 1019-1030 (2008).
    • Smithgall, M.D., Comeau, M.R., Yoon, B.R., Kaufman, D., Armitage, R. & Smith, D.E. IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells. Int. Immunol. 20, 1019-1030 (2008).
  • 123
    • 60449084238 scopus 로고    scopus 로고
    • TSLP in epithelial cell and dendritic cell cross talk
    • Liu, Y.J. TSLP in epithelial cell and dendritic cell cross talk. Adv. Immunol. 101, 1-25 (2009).
    • (2009) Adv. Immunol , vol.101 , pp. 1-25
    • Liu, Y.J.1
  • 124
    • 34247891512 scopus 로고    scopus 로고
    • TSLP: An epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation
    • Liu, Y.J. et al. TSLP: An epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation. Annu. Rev. Immunol. 25, 193-219 (2007).
    • (2007) Annu. Rev. Immunol , vol.25 , pp. 193-219
    • Liu, Y.J.1
  • 125
    • 20444415309 scopus 로고    scopus 로고
    • Human TSLP promotes CD40 ligand-induced IL-12 production by myeloid dendritic cells but maintains their Th2 priming potential
    • Watanabe, N., Hanabuchi, S., Marloie-Provost, M. A., Antonenko, S., Liu, Y.J. & Soumelis, V. Human TSLP promotes CD40 ligand-induced IL-12 production by myeloid dendritic cells but maintains their Th2 priming potential. Blood 105, 4749-4751 (2005).
    • (2005) Blood , vol.105 , pp. 4749-4751
    • Watanabe, N.1    Hanabuchi, S.2    Marloie-Provost, M.A.3    Antonenko, S.4    Liu, Y.J.5    Soumelis, V.6
  • 126
    • 36249027661 scopus 로고    scopus 로고
    • Differential role of thymic stromal lymphopoietin in the induction of airway hyperreactivity and Th2 immune response in antigen-induced asthma with respect to natural killer T cell function
    • Nagata, Y., Kamijuku, H., Taniguchi, M., Ziegler, S. & Seino, K. Differential role of thymic stromal lymphopoietin in the induction of airway hyperreactivity and Th2 immune response in antigen-induced asthma with respect to natural killer T cell function. Int. Arch. Allergy Immunol. 144, 305-314 (2007).
    • (2007) Int. Arch. Allergy Immunol , vol.144 , pp. 305-314
    • Nagata, Y.1    Kamijuku, H.2    Taniguchi, M.3    Ziegler, S.4    Seino, K.5
  • 127
    • 46749097474 scopus 로고    scopus 로고
    • The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases
    • Meylan, F. et al. The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases. Immunity 29, 79-89 (2008).
    • (2008) Immunity , vol.29 , pp. 79-89
    • Meylan, F.1
  • 128
    • 43549110073 scopus 로고    scopus 로고
    • Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation
    • Fang, L., Adkins, B., Deyev, V. & Podack, E.R. Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation. J. Exp. Med. 205, 1037-1048 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 1037-1048
    • Fang, L.1    Adkins, B.2    Deyev, V.3    Podack, E.R.4
  • 129
    • 45949091620 scopus 로고    scopus 로고
    • ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival
    • Akbari, O. et al. ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival. J. Immunol. 180, 5448-5456 (2008).
    • (2008) J. Immunol , vol.180 , pp. 5448-5456
    • Akbari, O.1
  • 130
    • 0242516124 scopus 로고    scopus 로고
    • Nonredundant roles for CD1d-restricted natural killer T cells and conventional CD4+ T cells in the induction of immunoglobulin E antibodies in response to interleukin 18 treatment of mice
    • Yoshimoto, T. et al. Nonredundant roles for CD1d-restricted natural killer T cells and conventional CD4+ T cells in the induction of immunoglobulin E antibodies in response to interleukin 18 treatment of mice. J. Exp. Med. 197, 997-1005 (2003).
    • (2003) J. Exp. Med , vol.197 , pp. 997-1005
    • Yoshimoto, T.1
  • 131
    • 55449129909 scopus 로고    scopus 로고
    • Interleukin-18-deficient mice exhibit diminished chronic inflammation and airway remodelling in ovalbumin-induced asthma model
    • Yamagata, S., Tomita, K., Sato, R., Niwa, A., Higashino, H. & Tohda, Y. Interleukin-18-deficient mice exhibit diminished chronic inflammation and airway remodelling in ovalbumin-induced asthma model. Clin. Exp. Immunol. 154, 295-304 (2008).
    • (2008) Clin. Exp. Immunol , vol.154 , pp. 295-304
    • Yamagata, S.1    Tomita, K.2    Sato, R.3    Niwa, A.4    Higashino, H.5    Tohda, Y.6
  • 132
    • 27644586260 scopus 로고    scopus 로고
    • Alpha-galactosylceramide-induced iNKT cells suppress experimental allergic asthma in sensitized mice: Role of IFN-gamma
    • Hachem, P. et al. Alpha-galactosylceramide-induced iNKT cells suppress experimental allergic asthma in sensitized mice: Role of IFN-gamma. Eur. J. Immunol. 35, 2793-2802 (2005).
    • (2005) Eur. J. Immunol , vol.35 , pp. 2793-2802
    • Hachem, P.1
  • 133
    • 21844476225 scopus 로고    scopus 로고
    • alpha-Galactosylceramide, a ligand of natural killer T cells, inhibits allergic airway inflammation
    • Matsuda, H. et al. alpha-Galactosylceramide, a ligand of natural killer T cells, inhibits allergic airway inflammation. Am. J. Respir. Cell Mol. Biol. 33, 22-31 (2005).
    • (2005) Am. J. Respir. Cell Mol. Biol , vol.33 , pp. 22-31
    • Matsuda, H.1
  • 134
    • 27644504027 scopus 로고    scopus 로고
    • Suppression of eosinophilic airway inflammation by treatment with alpha-galactosylceramide
    • Morishima, Y. et al. Suppression of eosinophilic airway inflammation by treatment with alpha-galactosylceramide. Eur. J. Immunol. 35, 2803-2814 (2005).
    • (2005) Eur. J. Immunol , vol.35 , pp. 2803-2814
    • Morishima, Y.1
  • 135
    • 27644474947 scopus 로고    scopus 로고
    • Exploiting the innate immune system to control allergic asthma
    • Dombrowicz, D. Exploiting the innate immune system to control allergic asthma. Eur. J. Immunol. 35, 2786-2788 (2005).
    • (2005) Eur. J. Immunol , vol.35 , pp. 2786-2788
    • Dombrowicz, D.1
  • 136
    • 13144249230 scopus 로고    scopus 로고
    • Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells
    • Kawano, T. et al. Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells. Proc. Natl. Acad. Sci. USA 95, 5690-5693 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5690-5693
    • Kawano, T.1
  • 137
    • 0033197917 scopus 로고    scopus 로고
    • Cutting edge: Inhibition of experimental tumor metastasis by dendritic cells pulsed with alpha-galactosylceramide
    • Toura, I., Kawano, T., Akutsu, Y., Nakayama, T., Ochiai, T. & Taniguchi, M. Cutting edge: Inhibition of experimental tumor metastasis by dendritic cells pulsed with alpha-galactosylceramide. J. Immunol. 163, 2387-2391 (1999).
    • (1999) J. Immunol , vol.163 , pp. 2387-2391
    • Toura, I.1    Kawano, T.2    Akutsu, Y.3    Nakayama, T.4    Ochiai, T.5    Taniguchi, M.6
  • 138
    • 33748474186 scopus 로고    scopus 로고
    • Dendritic cells pulsed with alpha-galactosylceramide induce anti-tumor immunity against pancreatic cancer in vivo
    • Nagaraj, S., Ziske, C., Strehl, J., Messmer, D., Sauerbruch, T. & Schmidt-Wolf, I.G. Dendritic cells pulsed with alpha-galactosylceramide induce anti-tumor immunity against pancreatic cancer in vivo. Int. Immunol. 18, 1279-1283 (2006).
    • (2006) Int. Immunol , vol.18 , pp. 1279-1283
    • Nagaraj, S.1    Ziske, C.2    Strehl, J.3    Messmer, D.4    Sauerbruch, T.5    Schmidt-Wolf, I.G.6
  • 139
    • 0041422186 scopus 로고    scopus 로고
    • Alpha-galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis
    • Hayakawa, Y., Rovero, S., Forni, G. & Smyth, M.J. Alpha-galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis. Proc. Natl. Acad. Sci. USA 100, 9464-9469 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9464-9469
    • Hayakawa, Y.1    Rovero, S.2    Forni, G.3    Smyth, M.J.4
  • 140
    • 0036735859 scopus 로고    scopus 로고
    • Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs
    • Fujii, S., Shimizu, K., Kronenberg, M. & Steinman, R.M. Prolonged IFN-gamma-producing NKT response induced with alpha-galactosylceramide-loaded DCs. Nat. Immunol. 3, 867-874 (2002).
    • (2002) Nat. Immunol , vol.3 , pp. 867-874
    • Fujii, S.1    Shimizu, K.2    Kronenberg, M.3    Steinman, R.M.4
  • 141
    • 20144388064 scopus 로고    scopus 로고
    • A phase I study of alpha-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer
    • Ishikawa, A. et al. A phase I study of alpha-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer. Clin. Cancer Res. 11, 1910-1917 (2005).
    • (2005) Clin. Cancer Res , vol.11 , pp. 1910-1917
    • Ishikawa, A.1
  • 142
    • 0038052875 scopus 로고    scopus 로고
    • Human peripheral blood Valpha24+ Vbeta11+ NKT cells expand following administration of alpha-galactosylceramide-pulsed dendritic cells
    • Okai, M. et al. Human peripheral blood Valpha24+ Vbeta11+ NKT cells expand following administration of alpha-galactosylceramide-pulsed dendritic cells. Vox. Sang. 83, 250-253 (2002).
    • (2002) Vox. Sang , vol.83 , pp. 250-253
    • Okai, M.1
  • 143
    • 37349014075 scopus 로고    scopus 로고
    • Phase I study of alpha-galactosylceramide-pulsed antigen presenting cells administration to the nasal submucosa in unresectable or recurrent head and neck cancer
    • Uchida, T. et al. Phase I study of alpha-galactosylceramide-pulsed antigen presenting cells administration to the nasal submucosa in unresectable or recurrent head and neck cancer. Cancer Immunol. Immunother. 57, 337-345 (2008).
    • (2008) Cancer Immunol. Immunother , vol.57 , pp. 337-345
    • Uchida, T.1
  • 144
    • 85185118794 scopus 로고    scopus 로고
    • Fujii, S. et al. Glycolipid alpha-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice. Proc. Natl. Acad. Sci. USA (2006)## 103, 11252-11257.
    • Fujii, S. et al. Glycolipid alpha-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice. Proc. Natl. Acad. Sci. USA (2006)## 103, 11252-11257.
  • 145
    • 0345167831 scopus 로고    scopus 로고
    • Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-galactosylceramide
    • Schmieg, J., Yang, G., Franck, R.W. & Tsuji, M. Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-galactosylceramide. J. Exp. Med. 198, 1631-1641 (2003).
    • (2003) J. Exp. Med , vol.198 , pp. 1631-1641
    • Schmieg, J.1    Yang, G.2    Franck, R.W.3    Tsuji, M.4
  • 146
    • 0035807302 scopus 로고    scopus 로고
    • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
    • Miyamoto, K., Miyake, S. & Yamamura, T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 413, 531-534 (2001).
    • (2001) Nature , vol.413 , pp. 531-534
    • Miyamoto, K.1    Miyake, S.2    Yamamura, T.3
  • 147
    • 2942739333 scopus 로고    scopus 로고
    • The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells
    • Oki, S., Chiba, A., Yamamura, T. & Miyake, S. The clinical implication and molecular mechanism of preferential IL-4 production by modified glycolipid-stimulated NKT cells. J. Clin. Invest. 113, 1631-1640 (2004).
    • (2004) J. Clin. Invest , vol.113 , pp. 1631-1640
    • Oki, S.1    Chiba, A.2    Yamamura, T.3    Miyake, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.