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Volumn 493, Issue 1, 2001, Pages 45-49
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Tyrosine-1290 of tetanus neurotoxin plays a key role in its binding to gangliosides and functional binding to neurones
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Author keywords
Botulinum; Ganglioside; Motoneuron; Neurotoxin; Receptor; Tetanus
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Indexed keywords
GANGLIOSIDE;
GLYCINE;
MUTANT PROTEIN;
NEUROTOXIN;
NEUROTRANSMITTER;
POLYSIALOGANGLIOSIDE DERIVATIVE;
TETANUS TOXIN;
TREFOIL PEPTIDE;
TYROSINE;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ARTICLE;
BRAIN SYNAPTOSOME;
CARBOXY TERMINAL SEQUENCE;
CONTROLLED STUDY;
EMBRYO;
INHIBITION KINETICS;
MEMBRANE BINDING;
NERVE CELL;
NEUROMUSCULAR SYNAPSE;
NEUROTRANSMITTER RELEASE;
NONHUMAN;
PRIORITY JOURNAL;
PROTEIN DOMAIN;
RAT;
SITE DIRECTED MUTAGENESIS;
SPINAL CORD;
STRUCTURE ACTIVITY RELATION;
SYNAPTIC MEMBRANE;
ANIMALS;
BINDING, COMPETITIVE;
BRAIN;
GANGLIOSIDES;
KINETICS;
LIGANDS;
MODELS, MOLECULAR;
MUTAGENESIS, SITE-DIRECTED;
MUTATION;
NEURONS;
POTASSIUM;
PROTEIN BINDING;
PROTEIN STRUCTURE, TERTIARY;
RATS;
SPINAL CORD;
TETANUS TOXIN;
TYROSINE;
LOTUS;
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EID: 0035937477
PISSN: 00145793
EISSN: None
Source Type: Journal
DOI: 10.1016/S0014-5793(01)02273-6 Document Type: Article |
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Times cited : (27)
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References (23)
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