Complex gangliosides at the neuromuscular junction are membrane receptors for autoantibodies and botulinum neurotoxin but redundant for normal synaptic function

Journal of Neuroscience

Volumn 22, Issue 16, 2002, Pages 6876-6884

  Bullens, Roland W M ^a   O'Hanlon, Graham M ^b   Wagner, Eric ^b   Molenaar, Peter C ^a   Furukawa, Keiko ^c   Furukawa, Koichi ^c   Plomp, Jaap J ^a   Willison, Hugh J ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SOUTHERN GENERAL HOSPITAL   (United Kingdom)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Anti ganglioside antibodies; Botulinum neurotoxin; Complex gangliosides; Miller Fisher syndrome; Neuromuscular junction; Synaptic transmission; 1,4 GalNAc transferase

Indexed keywords

AUTOANTIBODY; BOTULINUM TOXIN; BOTULINUM TOXIN A; GANGLIOSIDE; GANGLIOSIDE ANTIBODY; GANGLIOSIDE GD2; GLYCOLIPID; MEMBRANE RECEPTOR; TRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME MECHANISM; MOLECULAR MIMICRY; MOUSE; NEUROMUSCULAR SYNAPSE; NEUROPATHY; NEUROTRANSMITTER RELEASE; NONHUMAN; PATHOPHYSIOLOGY; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; SYNTHESIS;

EID: 0037104801     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-16-06876.2002     Document Type: Article

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