Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin-neuron interaction

PLoS Pathogens

Volumn 4, Issue 8, 2008, Pages

  Stenmark, Pål ^a   Dupuy, Jérôme ^a   Imamura, Akihiro ^b   Kiso, Makoto ^b   Stevens, Raymond C ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BOTULINUM TOXIN A; BOTULINUM TOXIN B; CELL SURFACE RECEPTOR; GANGLIOSIDE GT 1B; TRYPTOPHAN; GANGLIOSIDE; TRISIALOGANGLIOSIDE GT1;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; CELL INTERACTION; CELL SURFACE; CRYSTAL STRUCTURE; HYDROGEN BOND; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; TOXIN STRUCTURE; ANIMAL; CHEMISTRY; HUMAN; METABOLISM; NERVE CELL; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; BOTULINUM TOXIN TYPE A; CRYSTALLOGRAPHY, X-RAY; GANGLIOSIDES; HUMANS; NEURONS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 50849107858     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000129     Document Type: Article

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