Mitotic drivers-inhibitors of the Aurora B Kinase

Cancer and Metastasis Reviews

Volumn 28, Issue 1-2, 2009, Pages 185-195

  Keen, Nicholas ^a   Taylor, Stephen ^b  

^a ASTRAZENECA   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Anti mitotic; Aurora Kinase; Cancer; Cell cycle; Mitosis; Therapeutic

Indexed keywords

2 [[3 [4 [5 [2 (3 FLUOROANILINO) 2 OXOETHYL] 1H PYRAZOL 3 YLAMINO] 7 QUINAZOLINYLOXY]PROPYL](ETHYL)AMINO]ETHYL DIHYDROGEN PHOSPHATE; 4 [[9 CHLORO 7 (2,6 DIFLUOROPHENYL) 5H PYRIMIDO[5,4 D][2]BENZAZEPIN 2 YL]AMINO]BENZOIC ACID; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; AS 703569; AT 9283; AURORA A KINASE INHIBITOR; AURORA B KINASE INHIBITOR; AURORA KINASE INHIBITOR; BI 2536; CK 0106023; CYC 116; CYCLOPROPANECARBOXYLIC ACID [4 [4 (4 METHYL 1 PIPERAZINYL) 6 (5 METHYL 2H PYRAZOL 3 YLAMINO) 2 PYRIMIDINYLTHIO]PHENYL]AMIDE; HESPERADIN; IMATINIB; ISPINESIB; KINESIN; KINESIN SPINDLE PROTEIN; KINESIN SPINDLE PROTEIN INHIBITOR; KW 2449; MK 0731; MONASTROL; N [4 [6 METHOXY 7 (3 MORPHOLINOPROPOXY) 4 QUINAZOLINYLAMINO]PHENYL]BENZAMIDE; ON 01910; PACLITAXEL; PHA 739358; POLO LIKE KINASE 1 INHIBITOR; R 763; SB 743921; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG; XL 228; AURORA KINASE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE;

ACUTE GRANULOCYTIC LEUKEMIA; ANOREXIA; ANTINEOPLASTIC ACTIVITY; BONE MARROW SUPPRESSION; BREAST CARCINOMA; CANCER CELL; CANCER INHIBITION; CANCER RESISTANCE; CELL CYCLE ARREST; CHEMOTHERAPY INDUCED EMESIS; CLINICAL TRIAL; COLON ADENOCARCINOMA; COLON CANCER; CONTINUOUS INFUSION; DIARRHEA; DOSE CALCULATION; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG MECHANISM; DRUG TARGETING; DRUG WITHDRAWAL; DYSPNEA; FATIGUE; HAIR LOSS; HEART ATRIUM FIBRILLATION; HEART MUSCLE ISCHEMIA; HEART VENTRICLE ARRHYTHMIA; HEMATOLOGIC MALIGNANCY; HUMAN; IC 50; INJECTION SITE REACTION; LIVER CELL CARCINOMA; MELANOMA; METASTASIS; MICROTUBULE; MITOSIS INHIBITION; MITOSIS SPINDLE; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUROPATHY; NEUTROPENIA; NONHUMAN; OVARY CANCER; PANCREAS CANCER; PERIPHERAL NEUROPATHY; PLEURA EFFUSION; PNEUMONIA; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROSTATE CANCER; QT PROLONGATION; RECURRENT CANCER; REVIEW; SOLID TUMOR; SOMNOLENCE; SQUAMOUS CELL CARCINOMA; TREATMENT DURATION; TREATMENT RESPONSE; WEIGHT REDUCTION; ANIMAL; BIOLOGICAL MODEL; CELL CYCLE; CHEMISTRY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; DRUG RESISTANCE; METABOLISM; METHODOLOGY; MITOSIS; NEOPLASM; ONCOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, NEOPLASM; HUMANS; MEDICAL ONCOLOGY; MICROTUBULES; MITOSIS; MITOTIC SPINDLE APPARATUS; MODELS, BIOLOGICAL; NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES;

EID: 68549120912     PISSN: 01677659     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10555-009-9184-9     Document Type: Review

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