ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent

Cancer Cell

Volumn 7, Issue 3, 2005, Pages 275-286

  Gumireddy, Kiranmai ^a   Reddy, M V Ramana ^a   Cosenza, Stephen C ^a   Nathan, R Boomi ^a   Baker, Stacey J ^a   Papathi, Nabisa ^a   Jiang, Jiandong ^b   Holland, James ^b   Reddy, E Premkumar ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; BLEOMYCIN; CAMPTOTHECIN; DACTINOMYCIN; DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; GEMCITABINE; MITOXANTRONE; ON 01910; OXALIPLATIN; PACLITAXEL; POLO LIKE KINASE 1; SMALL MOLECULE TRANSPORT AGENT; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD TOXICITY; BONE MARROW TOXICITY; BREAST ADENOCARCINOMA; CARDIOTOXICITY; CONTROLLED STUDY; DOG; DRUG POTENCY; DRUG POTENTIATION; DRUG SAFETY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; FEMALE; FLATULENCE; GASTROINTESTINAL SYMPTOM; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LIVER INJURY; MALE; MITOSIS INHIBITION; NEUROPATHY; NEUROTOXICITY; NONHUMAN; NUDE MOUSE; PANCREAS CANCER; PRIORITY JOURNAL; RAT; SPINDLE CELL; TUMOR CELL; TUMOR GROWTH; TUMOR REGRESSION; XENOGRAFT;

MUS MUSCULUS;

EID: 17644368237     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2005.02.009     Document Type: Article

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