Environmental toxicants inhibit neuronal Jak tyrosine kinase by mitochondrial disruption

NeuroToxicology

Volumn 30, Issue 4, 2009, Pages 589-598

  Monroe, Richard K ^a   Halvorsen, Stanley W ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Cadmium toxicity; Ciliary neurotrophic factor; Interferon ; Oxidative stress; Rotenone; Tyrosine nitration

Indexed keywords

2,6 DICHLOROPHENOLINDOPHENOL; CADMIUM CHLORIDE; CILIARY NEUROTROPHIC FACTOR; GAMMA INTERFERON; INTERLEUKIN 6; JANUS KINASE; JANUS KINASE 1; JANUS KINASE 2; MERCURY CHLORIDE; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; STAT PROTEIN; SUPEROXIDE; THIOCTIC ACID; TYROSINE; UBIQUINOL CYTOCHROME C REDUCTASE;

ARTICLE; AUTOPHOSPHORYLATION; CELL STRAIN HEPG2; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE DEGENERATION; NEUROBLASTOMA CELL; NEUROTOXICITY; NITRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

2,6-DICHLOROINDOPHENOL; ANTIOXIDANTS; CADMIUM CHLORIDE; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CILIARY NEUROTROPHIC FACTOR; DRUG INTERACTIONS; ENVIRONMENTAL POLLUTANTS; HUMANS; IMMUNOPRECIPITATION; JANUS KINASES; LIVER NEOPLASMS; MERCURY COMPOUNDS; MITOCHONDRIA; NEUROBLASTOMA; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY, ATOMIC; STAT TRANSCRIPTION FACTORS; SUPEROXIDES; THIOCTIC ACID; TRANSFECTION;

EID: 67651083454     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2009.03.007     Document Type: Article

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