Identification of functional receptors for ciliary neurotrophic factor on chick ciliary ganglion neurons

Neuroscience

Volumn 72, Issue 3, 1996, Pages 821-832

  Koshlukova, S ^a   Finn, T P ^b   Nishi, R ^b   Halvorsen, S W ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

CNTF; cytokines; glycosylphosphatidylinositol linked protein; growth promoting activity; receptor binding; tyrosine phosphorylation

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CYTOKINE; INTERLEUKIN 11; INTERLEUKIN 6; ONCOSTATIN; PHOSPHOLIPASE C; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHICKEN; CILIARY GANGLION; CONTROLLED STUDY; EMBRYO; NERVE GROWTH; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 0029865768     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(95)00560-9     Document Type: Article

References (48)

1. Adler R., Landa K., Manthorpe M. and Varon S. (1979) Cholinergic neurotrophic factors: intraocular distribution of soluble trophic activity for ciliary neurons. Science 204, 1434-1436.
2. Akira S., Nishio Y., Inoue M., Wang X., Wei S., Matsusaka T., Yoshida K., Sudo T., Narubto M. and Kishimoto T. (1994) Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp 130-mediated signaling pathway. Cell 76, 63-71.
3. Bazan F. J. (1991) Neuropoietic cytokines in the hematopoietic fold. Neuron 7, 197-208.
4. Bothwell M. (1991) Keeping track of neurotrophin receptors. Cell 65, 915-918.
5. Boulton T. G., Stahl N. and Yancopoulos G. D. (1994) Ciliary neurotrophic factor, leukemia inhibitory factor, interleukin-6, oncostatin-M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors. J. biol. Chem. 269, 11,648-11,655.
6. Davis S., Aldrich T., Stahl N., Ip N. and Yancopoulos G. (1993) LIFRβ and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. Science 260, 1805-1808.
7. Davis S., Aldrich T., Valenzuela D., Wong V., Furth M., Squinto S. and Yancopoulos G. (1991) The receptor for ciliary neurotrophic factor. Science 253, 59-63.
8. Eckenstein F. P., Esch F., Holbert T., Blacher R. W. and Nishi R. (1990) Purification and characterization of a trophic factor for embryonic peripheral neurons: comparison with fibroblast growth factors. Neuron 4, 623-631.
9. Fann M. J. and Patterson P. H. (1994) Neuropoietic cytokines and activin-a differentially regulate the phenotype of cultured sympathetic neurons. Proc. natn. Acad. Sci. U.S.A. 91, 43-47.
10. Gearing D. P., Comeau M. R., Friend D. J., Gimpel S. D., Thut C. J., McGourty J., Brasher K. K., King J. A., Gillis S., Mosley B., Ziegler S. F. and Cosman D. (1992) The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor. Science 255, 1434-1437.
11. Halvorsen S. W. and Berg D. K. (1986) Identification of a nicotinic acetylcholine receptor on neurons using an α-neurotoxin that blocks receptor function. J. Neurosci. 6, 3405-3412.
12. Halvorsen S. W. and Berg D. K. (1987) Affinity labeling of neuronal acetylcholine receptor subunits with an α-neurotoxin that blocks receptor function. J. Neurosci. 7, 2547-2555.
13. Halvorsen S. W. and Berg D. K. (1989) Specific down-regulation of the α-bungarotoxin binding site on chick autonomic neurons by ciliary neuronotrophic factor. J. Neurosci. 9, 3673-3680.
14. Halvorsen S. W., Malek R., Wang X. and Jiang N. (1996) Ciliary neurotrophic factor regulates nicotinic acetylcholine receptors on human neuroblastoma cells. Neuropharmacology (in press).
15. Halvorsen S. W., McEachern A. E., Schmid H. A. and Berg D. K. (1991) Regulation of acetylcholine receptors on chick ciliary ganglion neurons by components from the synaptic target tissue. J. Neurosci. 11, 2177-2186.
16. Halvorsen S. W. and Nathanson N. M. (1981) In vivo regulation of muscarinic acetylcholine receptor number and function in embryonic chick heart. J. biol. Chem. 256, 7941-7948.
17. Heller S., Finn T. P., Huber J., Nishi R., Geiben M., Püschel A. and Rohrer H. (1995) Analysis of function and expression of the chick GPA receptor (GPARα) suggests multiple roles in neuronal development. Development 121, 2681-2693.
18. Heller S., Huber J., Finn T. P., Nishi R. and Rohrer H. (1993) GPA and CNTF produce similar effects in sympathetic neurones but differ in receptor binding. NeuroReport 5, 357-360.
19. Hilton D. J., Hilton A. A., Raicevic A., Rakar S., Harrisonsmith M., Gough N. M., Begley C. G., Metcalf D., Nicola N. A. and Willson T. A. (1994) Cloning of a murine IL-11 receptor alpha-chain - requirement for gp130 for high affinity binding and signal transduction. Eur. molec. Biol. Org. J. 13, 4765-4775.
20. Hofmann H.-D. (1988) Ciliary neuronotrophic factor stimulates choline acetyltransferase activity in cultured chicken retina neurons. J. Neurochem. 51, 109-113.
21. Huber J., Dittrich F. and Phelan P. (1993) Characterization of high-affinity and low-affinity receptors for ciliary neurotrophic factor. Eur. J. Biochem. 218, 1031-1039.
22. Ip N. Y., McClain J., Barrezueta N., Aldrich T., Pan L., Li Y., Wiegand S., Friedman B., Davis S. and Yancopoulos G. (1993) The a component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development. Neuron 10, 89-102.
23. Jacob M. J. and Berg D. K. (1983) The ultrastructural localization of α-bungarotoxin binding sites in relation to synapses on chick ciliary ganglion neurons. J. Neurosci. 3, 260-271.
24. Kishimoto T., Akira S. and Taga T. (1992) Interleukin-6 and its receptor: a paradigm for cytokines. Science 258, 593-597.
25. Kishimoto T., Taga T. and Akira S. (1994) Cytokine signal transduction. Cell 76, 253-262.
26. Landmesser L. and Pilar G. (1972) The onset and development of transmission in the chick ciliary ganglion. J. Physiol., Lond. 222, 691-713.
27. Landmesser L. and Pilar G. (1974) Synaptic transmission and cell death during development. J. Physiol., Lond. 241, 737-749.
28. Leung D. W., Parent A. S., Cachianes G., Esch F., Coulombe J. N., Nikolich K., Eckenstein F. P. and Nishi R. (1992) Cloning, expression during development, and evidence for release of a trophic factor for ciliary ganglion neurons. Neuron 8, 1045-1053.
29. Lin L.-F., Armes L., Sommer A., Smith D. and Collins F. (1990) Isolation and characterization of ciliary neurotrophic factor from rabbit sciatic nerves. J. biol. Chem. 265, 8942-8947.
30. Lo D. (1993) A central role for ciliary neurotrophic factor? Proc. natn. Acad. Sci. U.S.A. 90, 2557-2558.
31. Manthorpe M., Fagnani R., Skaper S. and Varon S. (1986) An automated colorimetric microassay for neuronotrophic factors. Devl Brain Res. 25, 191-198.
32. Margiotta J. F. and Berg D. K. (1982) Functional synapses are established between ciliary ganglion neurones in dissociated cell culture. Nature 296, 152-154.
33. Nishi R. (1994) Target-derived molecules that influence the development of neurons in the avian ciliary ganglion. J. Neurobiol. 25, 612-619.
34. + concentrations on the growth and development of ciliary ganglion neurons in cell culture. Devl Biol. 87, 301-307.
35. Nishi R. and Berg D. K. (1981) Two components from eye tissue that differentially stimulate growth and development of ciliary ganglion neurons in culture. J. Neurosci. 1, 505-513.
36. Panayotatos N., Everdeen D., Liten A., Somogyi R. and Acheson A. (1994) Recombinant human CNTF receptor alpha - production, binding stoichiometry, and characterization of its activity as a diffusible factor. Biochemistry 1933, 5813-5818.
37. Panayotatos N., Radziejewski E., Acheson A., Pearsall D., Thadani A. and Wong V. (1993) Exchange of a single amino acid interconverts the specific activity and gel mobility of human and rat ciliary neurotrophic factors. J. biol. Chem. 258, 19,000-19,003.
38. Pang D., Sharma B. and Shafer J. (1985) Purification of the catalytically active phosphorylated form of insulin receptor kinase by affinity chromatography with phosphotyrosyl-binding antibodies. Archs Biochem. Biophys. 242, 176-186.
39. Pilar G., Landmesser L. and Burstein L. (1980) Competition for survival among developing ciliary ganglion cells. Neurophysiology 63, 233-254.
40. Rao M. S., Tyrrell S., Landis S., C. and Patterson P. H. (1992) Effects of ciliary neurotrophic factor (CNTF) and depolarization on neuropeptide expression in cultured sympathetic neurons. Devl Biol. 150, 281-293.
41. Sendtner M., Kreutzberg G. and Thoenen H. (1990) Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345, 440-441.
42. Stahl N., Boulton T., Farruggella T., Ip N., Davis S., Witthuhn B., Quelle F., Silvennoinen O., Barberi G., Pellegrini S., Ihle J. and Yancopoulos G. (1994) Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL6 β receptor components. Science 263, 92-95.
43. Stahl N., Davis S., Taga T., Kishimoto T., Ip N. and Yancopoulos G. (1993) Cross-linking identifies leukemia inhibitory factor-binding protein as a ciliary neurotrophic factor receptor component. J. biol. Chem. 268, 7628-7631.
44. Stahl N., Farruggella T., Boulton T., Zhong Z., Darnell J. Jr and Yancopoulos G. (1995) Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science 267, 1349-1353.
45. Stahl N. and Yancopoulos G. (1993) The alphas, betas, and kinases of cytokine receptor complexes. Cell 74, 587-590.
46. Taga T., Hibi M., Hirata Y., Yamasaki K., Yasukawa K., Matsuda T., Hirano T. and Kishimoto T. (1989) Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell 58, 573-581.
47. Wong V. V., Pearsall D., Arriaga R., Ip N. Y., Stahl N. and Lindsay R. M. (1995) Binding characteristics of ciliary neurotrophic factor to sympathetic neurons and neuronal cell lines. J. biol. Chem. 270, 313-318.
48. Zhang Z.-W., Vijayarhagavan S. and Berg D. K. (1994) Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels. Neuron 12, 167-177.